FI963645A0 - Silmänpainetta alentava aine - Google Patents
Silmänpainetta alentava aineInfo
- Publication number
- FI963645A0 FI963645A0 FI963645A FI963645A FI963645A0 FI 963645 A0 FI963645 A0 FI 963645A0 FI 963645 A FI963645 A FI 963645A FI 963645 A FI963645 A FI 963645A FI 963645 A0 FI963645 A0 FI 963645A0
- Authority
- FI
- Finland
- Prior art keywords
- group
- alkyl
- formula
- alkenyl
- carboxyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4540494 | 1994-03-16 | ||
JP4540494 | 1994-03-16 | ||
JP9500444 | 1995-03-16 | ||
PCT/JP1995/000444 WO1995024902A1 (fr) | 1994-03-16 | 1995-03-16 | Reducteur de tension oculaire |
Publications (3)
Publication Number | Publication Date |
---|---|
FI963645A0 true FI963645A0 (fi) | 1996-09-16 |
FI963645A FI963645A (fi) | 1996-11-14 |
FI114897B FI114897B (fi) | 2005-01-31 |
Family
ID=12718322
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI963645A FI114897B (fi) | 1994-03-16 | 1996-09-16 | Silmän sisäistä painetta alentavan aineen käyttö ja silmätipoiksi tehty lääke |
FI20041236A FI115197B (fi) | 1994-03-16 | 2004-09-24 | Yhdisteen käyttö silmälääkkeen valmistamiseksi yhdistelmänä beta-salpaajan kanssa ja silmätipoiksi tehty, silmissä paikallisesti käytettävä lääke |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI20041236A FI115197B (fi) | 1994-03-16 | 2004-09-24 | Yhdisteen käyttö silmälääkkeen valmistamiseksi yhdistelmänä beta-salpaajan kanssa ja silmätipoiksi tehty, silmissä paikallisesti käytettävä lääke |
Country Status (20)
Country | Link |
---|---|
US (1) | US5925664A (fi) |
EP (2) | EP0795326B1 (fi) |
KR (1) | KR100211446B1 (fi) |
CN (2) | CN1104898C (fi) |
AT (2) | ATE206050T1 (fi) |
AU (1) | AU684916B2 (fi) |
CZ (1) | CZ284395B6 (fi) |
DE (2) | DE69522955T2 (fi) |
DK (2) | DK1110551T3 (fi) |
ES (2) | ES2221872T3 (fi) |
FI (2) | FI114897B (fi) |
GR (1) | GR3036989T3 (fi) |
HK (1) | HK1000551A1 (fi) |
HU (1) | HUT74734A (fi) |
MX (1) | MX9604109A (fi) |
NO (1) | NO311068B1 (fi) |
NZ (1) | NZ282485A (fi) |
PT (2) | PT795326E (fi) |
RU (1) | RU2123847C1 (fi) |
WO (1) | WO1995024902A1 (fi) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL200009B1 (pl) * | 1999-06-11 | 2008-11-28 | Sankyo Co | Kompozycja obniżająca ciśnienie wewnątrzgałkowe oraz zastosowanie antagonisty angiotensyny II do obniżania ciśnienia wewnątrzgałkowego |
TWI290470B (en) * | 1999-12-01 | 2007-12-01 | Sankyo Co | The composition for treating glaucoma |
GR20000100281A (el) * | 2000-08-17 | 2002-05-24 | Ιωαννης Ματσουκας | Ανταγωνιστες του υποδοχεα της αγγεοτενσινης ιι και συνθετικες μεθοδοι για την θεραπεια της υπερτασης και καρδιοαγγειακων ασθενειων |
WO2002045748A1 (fr) * | 2000-12-05 | 2002-06-13 | Sankyo Company, Limited | Compositions d'abaissement de la tension oculaire pour administration topique |
KR101087519B1 (ko) * | 2003-04-15 | 2011-11-28 | 상꾜 가부시키가이샤 | 안구 내 혈관 신생성 질환의 예방 또는 치료를 위한 의약 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5138069A (en) * | 1986-07-11 | 1992-08-11 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking imidazoles |
JPS6323868A (ja) * | 1986-07-11 | 1988-02-01 | イー・アイ・デュポン・ドゥ・ヌムール・アンド・カンパニー | アンギオテンシン2受容体遮断性イミダゾ−ル |
CA1334092C (en) * | 1986-07-11 | 1995-01-24 | David John Carini | Angiotensin ii receptor blocking imidazoles |
US4820843A (en) * | 1987-05-22 | 1989-04-11 | E. I. Du Pont De Nemours And Company | Tetrazole intermediates to antihypertensive compounds |
CA1338238C (en) * | 1988-01-07 | 1996-04-09 | David John Carini | Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids |
WO1991000277A1 (en) * | 1989-06-30 | 1991-01-10 | E.I. Du Pont De Nemours And Company | Substituted imidazoles |
WO1991015206A1 (en) * | 1990-04-05 | 1991-10-17 | E.I. Du Pont De Nemours And Company | Treatment of glaucoma and ocular hypertension with imidazole angiotensin-ii receptor antagonists |
US5196444A (en) * | 1990-04-27 | 1993-03-23 | Takeda Chemical Industries, Ltd. | 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof |
US5126342A (en) * | 1990-10-01 | 1992-06-30 | Merck & Co., Inc. | Imidazole angiotensin ii antagonists incorporating acidic functional groups |
IE920540A1 (en) * | 1991-02-21 | 1992-08-26 | Sankyo Co | 1-biphenylmethylimidazole derivatives, their preparation and¹their therapetuic use |
US5616599A (en) * | 1991-02-21 | 1997-04-01 | Sankyo Company, Limited | Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use |
US5219856A (en) * | 1992-04-06 | 1993-06-15 | E. I. Du Pont De Nemours And Company | Angiotensin-II receptor blocking, heterocycle substituted imidazoles |
EP0573218B1 (en) * | 1992-06-02 | 2001-03-07 | Sankyo Company Limited | 4-Carboxyimidazoles as angiotensin II antagonists and their thrapeutic use |
US5310929A (en) * | 1992-08-06 | 1994-05-10 | E. I. Du Pont De Nemours And Company | Prodrugs of imidazole carboxylic acids as angiotensin II receptor antagonists |
CA2111662C (en) * | 1992-12-17 | 2004-11-23 | Hiroaki Yanagisawa | Biphenyl derivatives, their preparation and their use for the treatment of hypertension and cardiac disease |
CZ154994A3 (en) * | 1993-07-02 | 1995-09-13 | Senju Pharma Co | Visual hypotensive agent |
MX9603259A (es) * | 1994-02-08 | 1997-03-29 | Novartis Ag | Tratamiento de glaucoma normotensivo con antagonistas de angiotensina ii. |
-
1995
- 1995-03-16 HU HU9602534A patent/HUT74734A/hu unknown
- 1995-03-16 MX MX9604109A patent/MX9604109A/es not_active IP Right Cessation
- 1995-03-16 AU AU19602/95A patent/AU684916B2/en not_active Ceased
- 1995-03-16 EP EP95912428A patent/EP0795326B1/en not_active Expired - Lifetime
- 1995-03-16 AT AT95912428T patent/ATE206050T1/de not_active IP Right Cessation
- 1995-03-16 KR KR1019960705082A patent/KR100211446B1/ko not_active IP Right Cessation
- 1995-03-16 DE DE69522955T patent/DE69522955T2/de not_active Expired - Fee Related
- 1995-03-16 CN CN95193132A patent/CN1104898C/zh not_active Expired - Fee Related
- 1995-03-16 DK DK01102527T patent/DK1110551T3/da active
- 1995-03-16 ES ES01102527T patent/ES2221872T3/es not_active Expired - Lifetime
- 1995-03-16 NZ NZ282485A patent/NZ282485A/en not_active IP Right Cessation
- 1995-03-16 RU RU96121253A patent/RU2123847C1/ru active
- 1995-03-16 DE DE69533045T patent/DE69533045T2/de not_active Expired - Fee Related
- 1995-03-16 CZ CZ962694A patent/CZ284395B6/cs not_active IP Right Cessation
- 1995-03-16 DK DK95912428T patent/DK0795326T3/da active
- 1995-03-16 PT PT95912428T patent/PT795326E/pt unknown
- 1995-03-16 WO PCT/JP1995/000444 patent/WO1995024902A1/ja active IP Right Grant
- 1995-03-16 PT PT01102527T patent/PT1110551E/pt unknown
- 1995-03-16 EP EP01102527A patent/EP1110551B1/en not_active Expired - Lifetime
- 1995-03-16 ES ES95912428T patent/ES2163501T3/es not_active Expired - Lifetime
- 1995-03-16 AT AT01102527T patent/ATE266402T1/de not_active IP Right Cessation
-
1996
- 1996-09-13 NO NO19963854A patent/NO311068B1/no not_active IP Right Cessation
- 1996-09-16 US US08/725,197 patent/US5925664A/en not_active Expired - Fee Related
- 1996-09-16 FI FI963645A patent/FI114897B/fi active IP Right Grant
-
1997
- 1997-10-23 HK HK97102015A patent/HK1000551A1/xx not_active IP Right Cessation
-
2001
- 2001-10-24 GR GR20010401862T patent/GR3036989T3/el not_active IP Right Cessation
-
2002
- 2002-05-11 CN CNB021199396A patent/CN1202819C/zh not_active Expired - Fee Related
-
2004
- 2004-09-24 FI FI20041236A patent/FI115197B/fi active IP Right Grant
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Patent granted |
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