GR3036989T3 - Ocular tension depressant - Google Patents

Ocular tension depressant

Info

Publication number
GR3036989T3
GR3036989T3 GR20010401862T GR20010401862T GR3036989T3 GR 3036989 T3 GR3036989 T3 GR 3036989T3 GR 20010401862 T GR20010401862 T GR 20010401862T GR 20010401862 T GR20010401862 T GR 20010401862T GR 3036989 T3 GR3036989 T3 GR 3036989T3
Authority
GR
Greece
Prior art keywords
group
alkyl
formula
alkenyl
carboxyl
Prior art date
Application number
GR20010401862T
Other languages
English (en)
Inventor
Tomihisa Yokoyama
Tsunemichi Hosokawa
Hiroaki Yanagisawa
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of GR3036989T3 publication Critical patent/GR3036989T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
GR20010401862T 1994-03-16 2001-10-24 Ocular tension depressant GR3036989T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4540494 1994-03-16
PCT/JP1995/000444 WO1995024902A1 (fr) 1994-03-16 1995-03-16 Reducteur de tension oculaire

Publications (1)

Publication Number Publication Date
GR3036989T3 true GR3036989T3 (en) 2002-01-31

Family

ID=12718322

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20010401862T GR3036989T3 (en) 1994-03-16 2001-10-24 Ocular tension depressant

Country Status (20)

Country Link
US (1) US5925664A (el)
EP (2) EP0795326B1 (el)
KR (1) KR100211446B1 (el)
CN (2) CN1104898C (el)
AT (2) ATE266402T1 (el)
AU (1) AU684916B2 (el)
CZ (1) CZ284395B6 (el)
DE (2) DE69533045T2 (el)
DK (2) DK0795326T3 (el)
ES (2) ES2163501T3 (el)
FI (2) FI114897B (el)
GR (1) GR3036989T3 (el)
HK (1) HK1000551A1 (el)
HU (1) HUT74734A (el)
MX (1) MX9604109A (el)
NO (1) NO311068B1 (el)
NZ (1) NZ282485A (el)
PT (2) PT1110551E (el)
RU (1) RU2123847C1 (el)
WO (1) WO1995024902A1 (el)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000076543A1 (fr) * 1999-06-11 2000-12-21 Sankyo Company, Limited Composition permettant de reduire la tension oculaire et destinee a l'administration topique
TWI290470B (en) 1999-12-01 2007-12-01 Sankyo Co The composition for treating glaucoma
GR20000100281A (el) * 2000-08-17 2002-05-24 Ιωαννης Ματσουκας Ανταγωνιστες του υποδοχεα της αγγεοτενσινης ιι και συνθετικες μεθοδοι για την θεραπεια της υπερτασης και καρδιοαγγειακων ασθενειων
AU2002218527A1 (en) * 2000-12-05 2002-06-18 Sankyo Company Limited Ocular tension-lowering compositions for topical administration
TWI349549B (en) * 2003-04-15 2011-10-01 Sankyo Co Medicament for treatment of intraocular angiopoietic disease

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5138069A (en) * 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
JPS6323868A (ja) * 1986-07-11 1988-02-01 イー・アイ・デュポン・ドゥ・ヌムール・アンド・カンパニー アンギオテンシン２受容体遮断性イミダゾ−ル
US4820843A (en) * 1987-05-22 1989-04-11 E. I. Du Pont De Nemours And Company Tetrazole intermediates to antihypertensive compounds
CA1338238C (en) * 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
WO1991000277A1 (en) * 1989-06-30 1991-01-10 E.I. Du Pont De Nemours And Company Substituted imidazoles
WO1991015206A1 (en) * 1990-04-05 1991-10-17 E.I. Du Pont De Nemours And Company Treatment of glaucoma and ocular hypertension with imidazole angiotensin-ii receptor antagonists
US5196444A (en) * 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
US5126342A (en) * 1990-10-01 1992-06-30 Merck & Co., Inc. Imidazole angiotensin ii antagonists incorporating acidic functional groups
CA2229000C (en) * 1991-02-21 2002-04-09 Sankyo Company, Limited 1-biphenylimidazole derivatives, their preparation and their therapeutic use
US5616599A (en) * 1991-02-21 1997-04-01 Sankyo Company, Limited Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use
US5219856A (en) * 1992-04-06 1993-06-15 E. I. Du Pont De Nemours And Company Angiotensin-II receptor blocking, heterocycle substituted imidazoles
DE69329982T2 (de) * 1992-06-02 2001-09-27 Sankyo Co., Ltd. 4-Carboxyimidazolderivate als Angiotensin-II-Antagonisten und ihre therapeutische Verwendung
US5310929A (en) * 1992-08-06 1994-05-10 E. I. Du Pont De Nemours And Company Prodrugs of imidazole carboxylic acids as angiotensin II receptor antagonists
JP3501484B2 (ja) * 1992-12-17 2004-03-02 三共株式会社 ビフェニル誘導体
CZ154994A3 (en) * 1993-07-02 1995-09-13 Senju Pharma Co Visual hypotensive agent
EP0743852B1 (en) * 1994-02-08 2005-07-27 Novartis AG Treatment of normotensive glaucoma with valsartan

Also Published As

Publication number Publication date
HU9602534D0 (en) 1996-11-28
CN1202819C (zh) 2005-05-25
AU1960295A (en) 1995-10-03
ATE206050T1 (de) 2001-10-15
ES2221872T3 (es) 2005-01-16
EP1110551A2 (en) 2001-06-27
DE69533045D1 (de) 2004-06-17
FI963645A (fi) 1996-11-14
DE69522955D1 (de) 2001-10-31
NO963854D0 (no) 1996-09-13
ATE266402T1 (de) 2004-05-15
CZ269496A3 (en) 1996-12-11
NO963854L (no) 1996-11-14
ES2163501T3 (es) 2002-02-01
EP0795326A1 (en) 1997-09-17
CN1387846A (zh) 2003-01-01
MX9604109A (es) 1997-09-30
DK1110551T3 (da) 2004-06-07
NO311068B1 (no) 2001-10-08
PT795326E (pt) 2002-01-30
FI20041236A (fi) 2004-09-24
CN1104898C (zh) 2003-04-09
HK1000551A1 (en) 2002-04-12
PT1110551E (pt) 2004-07-30
DE69533045T2 (de) 2005-01-27
CZ284395B6 (cs) 1998-11-11
AU684916B2 (en) 1998-01-08
EP0795326B1 (en) 2001-09-26
FI114897B (fi) 2005-01-31
RU2123847C1 (ru) 1998-12-27
KR970701542A (ko) 1997-04-12
WO1995024902A1 (fr) 1995-09-21
FI963645A0 (fi) 1996-09-16
NZ282485A (en) 1997-06-24
DK0795326T3 (da) 2001-11-26
EP1110551A3 (en) 2001-08-16
KR100211446B1 (ko) 1999-08-02
EP0795326A4 (el) 1997-09-17
DE69522955T2 (de) 2002-05-29
HUT74734A (en) 1997-02-28
CN1148809A (zh) 1997-04-30
FI115197B (fi) 2005-03-31
EP1110551B1 (en) 2004-05-12
US5925664A (en) 1999-07-20

Similar Documents

Publication Publication Date Title
ATE194335T1 (de) 4,5-diaryloxazol-derivate
AU7372191A (en) 3,5-di-tertiarybutyl-4-hydroxyphenylemethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents
NO934792D0 (no) Xantinderivater
DE69728544D1 (de) Totalsynthese von acylfulvenen mit antitumorwirkung
ATE134366T1 (de) Amid derivate von vitamin d
DK0916651T3 (da) Phenylalkylcarboxylsyrederivater
ATE421524T1 (de) 5-ring-heterocyclen, ihre herstellung, ihre verwendung als inhibitoren der leukozytenadhäsion und sie enthaltende pharmazeutische präparate
ES2123756T3 (es) Derivados de piperazina.
AU684916B2 (en) Ocular tension depressant
ATE197297T1 (de) 3-oxo-1,4-benzothiazin-derivate
AU6599186A (en) N-(6-(4-0-hydrxyphenyl-1,3-dioxan-cis-5-yl)hexenoyl) suphonamide derivatives
NO893039L (no) Bruk av imidazopyrazol-derivater som analgesiske og antiinflammatoriske midler.
ATE212356T1 (de) Carbamoylmethylharnstoffderivate
EP0878475A3 (en) 5-(4-Piperidinyl)dibenzothiazepine derivatives and 5-(4-piperidinyl)dibenzoxazepine derivatives, and antiarrhythmic agents
AU653019B2 (en) New urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same
NO951798L (no) Terapeutiske midler

Legal Events

Date Code Title Description
ML Lapse due to non-payment of fees