ATE212356T1 - Carbamoylmethylharnstoffderivate - Google Patents
CarbamoylmethylharnstoffderivateInfo
- Publication number
- ATE212356T1 ATE212356T1 AT95907849T AT95907849T ATE212356T1 AT E212356 T1 ATE212356 T1 AT E212356T1 AT 95907849 T AT95907849 T AT 95907849T AT 95907849 T AT95907849 T AT 95907849T AT E212356 T1 ATE212356 T1 AT E212356T1
- Authority
- AT
- Austria
- Prior art keywords
- optionally substituted
- receptors
- cck
- substituted phenyl
- heterocyclic group
- Prior art date
Links
- NFODSNOCEFVBRY-UHFFFAOYSA-N 2-(carbamoylamino)acetamide Chemical class NC(=O)CNC(N)=O NFODSNOCEFVBRY-UHFFFAOYSA-N 0.000 title 1
- 108010089448 Cholecystokinin B Receptor Proteins 0.000 abstract 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 108010089335 Cholecystokinin A Receptor Proteins 0.000 abstract 2
- 102100034927 Cholecystokinin receptor type A Human genes 0.000 abstract 2
- 102000052874 Gastrin receptors Human genes 0.000 abstract 2
- 102100036016 Gastrin/cholecystokinin type B receptor Human genes 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
- 125000005346 substituted cycloalkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Paints Or Removers (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1518994 | 1994-02-09 | ||
| JP24155594 | 1994-10-05 | ||
| PCT/JP1995/000161 WO1995021856A1 (fr) | 1994-02-09 | 1995-02-07 | Derives du carbamoylmethyluree |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE212356T1 true ATE212356T1 (de) | 2002-02-15 |
Family
ID=26351304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95907849T ATE212356T1 (de) | 1994-02-09 | 1995-02-07 | Carbamoylmethylharnstoffderivate |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5739162A (de) |
| EP (1) | EP0739903B1 (de) |
| CN (1) | CN1145074A (de) |
| AT (1) | ATE212356T1 (de) |
| AU (1) | AU691565B2 (de) |
| BR (1) | BR9506763A (de) |
| CA (1) | CA2181986A1 (de) |
| DE (1) | DE69525145T2 (de) |
| ES (1) | ES2171531T3 (de) |
| FI (1) | FI963122A (de) |
| HU (1) | HU219913B (de) |
| MX (1) | MX9603171A (de) |
| NO (1) | NO963307L (de) |
| PT (1) | PT739903E (de) |
| RU (1) | RU2134684C1 (de) |
| TW (1) | TW294653B (de) |
| WO (1) | WO1995021856A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5804560A (en) * | 1995-01-06 | 1998-09-08 | Sibia Neurosciences, Inc. | Peptide and peptide analog protease inhibitors |
| CN1197451A (zh) * | 1995-08-07 | 1998-10-28 | 盐野义制药株式会社 | 氨基甲酰基甲基脲衍生物的制备方法 |
| US9428549B2 (en) * | 2013-07-16 | 2016-08-30 | Allegran, Inc. | Derivatives of N-urea substituted amino acids as formyl peptide receptor modulators |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0166355A2 (de) * | 1984-06-26 | 1986-01-02 | Merck & Co. Inc. | Substituierte Aminophenyl- und Acylaminophenyl-Verbindungen und deren pharmazeutische Zusammensetzungen |
| US5382590A (en) * | 1990-02-09 | 1995-01-17 | Rhone-Poulenc Rorer S.A. | N-phenyl-N-acetamidoglycinamides, their preparation and medicaments containing them |
| FR2667864B2 (fr) * | 1990-03-07 | 1994-08-05 | Rhone Poulenc Sante | Derives de n-phenyl glycinamides, leur preparation et les medicaments les contenant. |
| FR2659334B1 (fr) * | 1990-03-07 | 1992-05-15 | Rhone Poulenc Sante | Derives de n-phenyl glycinamide, leur preparation et les medicaments les contenant. |
| FR2659653B1 (fr) * | 1990-03-13 | 1992-05-22 | Rhone Poulenc Sante | Derives de l'uree, leur preparation et les medicaments les contenant. |
-
1995
- 1995-02-07 AU AU15905/95A patent/AU691565B2/en not_active Ceased
- 1995-02-07 RU RU96119576A patent/RU2134684C1/ru active
- 1995-02-07 PT PT95907849T patent/PT739903E/pt unknown
- 1995-02-07 WO PCT/JP1995/000161 patent/WO1995021856A1/ja active IP Right Grant
- 1995-02-07 US US08/687,433 patent/US5739162A/en not_active Expired - Fee Related
- 1995-02-07 ES ES95907849T patent/ES2171531T3/es not_active Expired - Lifetime
- 1995-02-07 CA CA002181986A patent/CA2181986A1/en not_active Abandoned
- 1995-02-07 MX MX9603171A patent/MX9603171A/es unknown
- 1995-02-07 AT AT95907849T patent/ATE212356T1/de not_active IP Right Cessation
- 1995-02-07 BR BR9506763A patent/BR9506763A/pt not_active IP Right Cessation
- 1995-02-07 DE DE69525145T patent/DE69525145T2/de not_active Expired - Fee Related
- 1995-02-07 HU HU9602187A patent/HU219913B/hu not_active IP Right Cessation
- 1995-02-07 CN CN95192442A patent/CN1145074A/zh active Pending
- 1995-02-07 EP EP95907849A patent/EP0739903B1/de not_active Expired - Lifetime
- 1995-02-08 TW TW084101068A patent/TW294653B/zh active
-
1996
- 1996-08-08 NO NO963307A patent/NO963307L/no not_active Application Discontinuation
- 1996-08-09 FI FI963122A patent/FI963122A/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR9506763A (pt) | 1997-10-07 |
| ES2171531T3 (es) | 2002-09-16 |
| HUT74950A (en) | 1997-03-28 |
| WO1995021856A1 (fr) | 1995-08-17 |
| FI963122A0 (fi) | 1996-08-09 |
| NO963307L (no) | 1996-10-09 |
| NO963307D0 (no) | 1996-08-08 |
| MX9603171A (es) | 1997-03-29 |
| RU2134684C1 (ru) | 1999-08-20 |
| CN1145074A (zh) | 1997-03-12 |
| CA2181986A1 (en) | 1995-08-17 |
| HU219913B (hu) | 2001-09-28 |
| DE69525145D1 (en) | 2002-03-14 |
| HU9602187D0 (en) | 1996-10-28 |
| AU691565B2 (en) | 1998-05-21 |
| TW294653B (de) | 1997-01-01 |
| US5739162A (en) | 1998-04-14 |
| FI963122A (fi) | 1996-08-09 |
| EP0739903B1 (de) | 2002-01-23 |
| DE69525145T2 (de) | 2002-08-29 |
| EP0739903A1 (de) | 1996-10-30 |
| PT739903E (pt) | 2002-05-31 |
| EP0739903A4 (de) | 1998-07-08 |
| AU1590595A (en) | 1995-08-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |