MX9302414A - Proceso para la fabricacion de pirrolidinas (s)-3-amino-1- substituidas. - Google Patents

Proceso para la fabricacion de pirrolidinas (s)-3-amino-1- substituidas.

Info

Publication number
MX9302414A
MX9302414A MX9302414A MX9302414A MX9302414A MX 9302414 A MX9302414 A MX 9302414A MX 9302414 A MX9302414 A MX 9302414A MX 9302414 A MX9302414 A MX 9302414A MX 9302414 A MX9302414 A MX 9302414A
Authority
MX
Mexico
Prior art keywords
pyrrolidines
amino
substituted
manufacture
propionylaminoü
Prior art date
Application number
MX9302414A
Other languages
English (en)
Inventor
Tung Van Le
F Gregory Spence
James Norton Wemple
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of MX9302414A publication Critical patent/MX9302414A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/22—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

Es descrito un novedoso proceso para preparar una pirrolidina (s)-3-amino-1-substituída empleada como un intermediario clave en la preparación de agentes antibacterianos de quinolona y naftiridona, donde la posición 7 está ocupada por una cadena lateral de 3-amino-pirrolidina estereoespecífica, a partir de ácido L-aspártico. El ácido L- aspártico es convertido en la (s)-3-aminopirrolidina deseada por vía de una novedosa transformación, de alto rendimiento, de una aziridina substituída.
MX9302414A 1992-04-27 1993-04-26 Proceso para la fabricacion de pirrolidinas (s)-3-amino-1- substituidas. MX9302414A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/874,657 US5177217A (en) 1992-04-27 1992-04-27 Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines

Publications (1)

Publication Number Publication Date
MX9302414A true MX9302414A (es) 1993-10-01

Family

ID=25364272

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9302414A MX9302414A (es) 1992-04-27 1993-04-26 Proceso para la fabricacion de pirrolidinas (s)-3-amino-1- substituidas.

Country Status (20)

Country Link
US (1) US5177217A (es)
EP (2) EP0638068B1 (es)
JP (1) JP3264928B2 (es)
KR (1) KR950701316A (es)
AT (1) ATE181549T1 (es)
AU (1) AU666736B2 (es)
CA (1) CA2133091C (es)
CZ (1) CZ285593B6 (es)
DE (1) DE69325452T2 (es)
DK (1) DK0638068T3 (es)
ES (1) ES2135477T3 (es)
FI (1) FI106122B (es)
GR (1) GR3031149T3 (es)
HU (1) HU220603B1 (es)
MX (1) MX9302414A (es)
NO (1) NO300969B1 (es)
NZ (1) NZ252850A (es)
RU (1) RU2101279C1 (es)
SK (1) SK281195B6 (es)
WO (1) WO1993022283A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5177217A (en) * 1992-04-27 1993-01-05 Warner-Lambert Company Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines
EP1138672A1 (en) * 1998-01-12 2001-10-04 Basilea Pharmaceutica AG Process for the preparation of 3-amino-pyrrolidine derivatives
US5977381A (en) * 1998-01-12 1999-11-02 Hoffmann-La Roche Inc. Process for making 3-amino-pyrolidine derivatives
AU6367399A (en) 1998-11-02 2000-05-22 Welfide Corporation Pyrrolidine compounds and medicinal utilization thereof
US6531594B2 (en) * 2000-08-24 2003-03-11 Mitsubishi Chemical Corporation Process for producing 1H-3-aminopyrrolidine and derivatives thereof
JP4481659B2 (ja) 2002-03-29 2010-06-16 株式会社カネカ １−ベンジル−３−アミノピロリジンの光学純度向上方法及びそれに用いられる塩
US20070073064A1 (en) * 2003-10-08 2007-03-29 Teijin Pharma Limited Method for producing aminopyrrolidine derivatives and intermediate compounds
TW200630337A (en) 2004-10-14 2006-09-01 Euro Celtique Sa Piperidinyl compounds and the use thereof
WO2007110449A1 (en) * 2006-03-29 2007-10-04 Euro-Celtique S.A. Benzenesulfonamide compounds and their use
US8937181B2 (en) 2006-04-13 2015-01-20 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
TW200815353A (en) 2006-04-13 2008-04-01 Euro Celtique Sa Benzenesulfonamide compounds and their use
US8399486B2 (en) 2007-04-09 2013-03-19 Purdue Pharma L.P. Benzenesulfonyl compounds and the use thereof
US8765736B2 (en) 2007-09-28 2014-07-01 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
CN111620802A (zh) * 2020-06-18 2020-09-04 山西千岫制药有限公司 一种头孢托罗中间体(r)-1-苄基-3-氨基吡咯烷的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4785119A (en) * 1985-10-11 1988-11-15 Tokyo Kasei Kogyo Co., Ltd. 3-aminopyrrolidine compound and process for preparation thereof
US4851418A (en) * 1987-08-21 1989-07-25 Warner-Lambert Company Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent
US4859776A (en) * 1988-03-11 1989-08-22 Abbott Laboratories (S)-7-(3-aminopyrrolidin-1-yl)-1-(ortho, para-difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid and method for its preparation
JP2995704B2 (ja) * 1989-02-17 1999-12-27 東京化成工業株式会社 光学活性な１ｈ−３−アミノピロリジン化合物の製造法
US4916141A (en) * 1989-03-28 1990-04-10 Warner-Lambert Company (S)-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
CA2036516A1 (en) * 1990-02-19 1991-08-20 Yoshikazu Asahina Optically active 8-methoxyouinolonecarboxylic acid derivatives, their preparative processes and their intermediates
US5177217A (en) * 1992-04-27 1993-01-05 Warner-Lambert Company Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines

Also Published As

Publication number Publication date
NO300969B1 (no) 1997-08-25
DK0638068T3 (da) 1999-11-22
SK129894A3 (en) 1995-05-10
NO944075D0 (no) 1994-10-26
EP0638068B1 (en) 1999-06-23
NZ252850A (en) 1996-10-28
EP0638068A1 (en) 1995-02-15
CZ285593B6 (cs) 1999-09-15
DE69325452D1 (de) 1999-07-29
RU94046013A (ru) 1996-10-10
SK281195B6 (sk) 2001-01-18
KR950701316A (ko) 1995-03-23
RU2101279C1 (ru) 1998-01-10
FI945000A0 (fi) 1994-10-24
WO1993022283A1 (en) 1993-11-11
CZ257694A3 (en) 1995-10-18
EP0911322A2 (en) 1999-04-28
CA2133091C (en) 2005-01-04
US5177217A (en) 1993-01-05
ES2135477T3 (es) 1999-11-01
HU220603B1 (hu) 2002-03-28
GR3031149T3 (en) 1999-12-31
AU4289993A (en) 1993-11-29
NO944075L (no) 1994-12-27
FI106122B (fi) 2000-11-30
JPH07506110A (ja) 1995-07-06
EP0911322A3 (en) 2001-06-13
FI945000A (fi) 1994-10-24
JP3264928B2 (ja) 2002-03-11
CA2133091A1 (en) 1993-11-11
HUT70218A (en) 1995-09-28
ATE181549T1 (de) 1999-07-15
AU666736B2 (en) 1996-02-22
DE69325452T2 (de) 2000-05-18

Similar Documents

Publication Publication Date Title
ID30373A (id) PARAHERKUAMIDA ANTIPARASIT (Pecahan P-962086)
NO881697D0 (no) Verktoeyenhet, verktoeydeler og fremgangsmaate for sammensetting av delene.
KR0145958B1 (en) Antibacterial agents
HU9301361D0 (en) Method for producing 4-aryl-piperazines and 4-aryl-piperidines
DE69333062D1 (de) 4-mercaptoacetylamino-[2]benzazepinon(3)- derivate, und verwendung als enkephalinase-inhibitoren
KR950702564A (ko) 비스-스타우로스포린 및 케이-252에이(K-25a)유도체(BIS-STAUROSPORINE AND K-252a DERIVATIVES)
DE69626660T2 (de) 2-alkylpyrrolidine
MX9302414A (es) Proceso para la fabricacion de pirrolidinas (s)-3-amino-1- substituidas.
DE69007695D1 (de) Fucosidase-Inhibitoren.
AU1097988A (en) Alkylmelatonins
ITRM930502A0 (it) Procedimento per la produzione di r amminocarnitina e s amminocarnitina.
NO903338D0 (no) Fremgangsmaate for mikrobiologisk fremstilling av l-carnitin.
ES2129053T3 (es) Nuevos derivados de fosfolipidos.
ES2061775T3 (es) Derivados de estrobirulina, su obtencion y empleo.
GR3005231T3 (es)
NO903599D0 (no) Minoxidilgel.
ES2040362T3 (es) Procedimiento para la preparacion de 2-(benzhidrilsulfonil)acetamida.
GB2266406B (en) High-power laser source
JO1770B1 (en) New formulations mainly composed of derivatives of sleepjestrol and the methods necessary to produce them
GR851013B (es)

Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees