ATE181549T1 - Verfahren zur herstellung von (s)-3-amino-1- substituiert-pirrolidine - Google Patents

Verfahren zur herstellung von (s)-3-amino-1- substituiert-pirrolidine

Info

Publication number
ATE181549T1
ATE181549T1 AT93912301T AT93912301T ATE181549T1 AT E181549 T1 ATE181549 T1 AT E181549T1 AT 93912301 T AT93912301 T AT 93912301T AT 93912301 T AT93912301 T AT 93912301T AT E181549 T1 ATE181549 T1 AT E181549T1
Authority
AT
Austria
Prior art keywords
pirrolidine
amino
substituted
producing
propionylaminoü
Prior art date
Application number
AT93912301T
Other languages
English (en)
Inventor
Tung Van Le
F Gregory Spence
James Norton Wemple
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of ATE181549T1 publication Critical patent/ATE181549T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/22—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT93912301T 1992-04-27 1993-04-16 Verfahren zur herstellung von (s)-3-amino-1- substituiert-pirrolidine ATE181549T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/874,657 US5177217A (en) 1992-04-27 1992-04-27 Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines

Publications (1)

Publication Number Publication Date
ATE181549T1 true ATE181549T1 (de) 1999-07-15

Family

ID=25364272

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93912301T ATE181549T1 (de) 1992-04-27 1993-04-16 Verfahren zur herstellung von (s)-3-amino-1- substituiert-pirrolidine

Country Status (20)

Country Link
US (1) US5177217A (de)
EP (2) EP0638068B1 (de)
JP (1) JP3264928B2 (de)
KR (1) KR950701316A (de)
AT (1) ATE181549T1 (de)
AU (1) AU666736B2 (de)
CA (1) CA2133091C (de)
CZ (1) CZ285593B6 (de)
DE (1) DE69325452T2 (de)
DK (1) DK0638068T3 (de)
ES (1) ES2135477T3 (de)
FI (1) FI106122B (de)
GR (1) GR3031149T3 (de)
HU (1) HU220603B1 (de)
MX (1) MX9302414A (de)
NO (1) NO300969B1 (de)
NZ (1) NZ252850A (de)
RU (1) RU2101279C1 (de)
SK (1) SK281195B6 (de)
WO (1) WO1993022283A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5177217A (en) * 1992-04-27 1993-01-05 Warner-Lambert Company Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines
EP1138672A1 (de) * 1998-01-12 2001-10-04 Basilea Pharmaceutica AG Verfahren zur Herstellung von 3-Aminopyrrolidinderivaten
US5977381A (en) * 1998-01-12 1999-11-02 Hoffmann-La Roche Inc. Process for making 3-amino-pyrolidine derivatives
CN1332726A (zh) 1998-11-02 2002-01-23 卫福有限公司 吡咯烷化合物及其药物用途
US6531594B2 (en) 2000-08-24 2003-03-11 Mitsubishi Chemical Corporation Process for producing 1H-3-aminopyrrolidine and derivatives thereof
WO2003082815A1 (fr) 2002-03-29 2003-10-09 Kaneka Corporation Procede d'amelioration de la purete optique de 1-benzyl-3- aminopyrrolidine et sel utilise dans ce procede
JPWO2005035493A1 (ja) * 2003-10-08 2006-12-21 帝人ファーマ株式会社 アミノピロリジン誘導体の製造方法および中間体化合物
TW200630337A (en) 2004-10-14 2006-09-01 Euro Celtique Sa Piperidinyl compounds and the use thereof
WO2007110449A1 (en) * 2006-03-29 2007-10-04 Euro-Celtique S.A. Benzenesulfonamide compounds and their use
US8791264B2 (en) 2006-04-13 2014-07-29 Purdue Pharma L.P. Benzenesulfonamide compounds and their use as blockers of calcium channels
US8937181B2 (en) 2006-04-13 2015-01-20 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
US8399486B2 (en) 2007-04-09 2013-03-19 Purdue Pharma L.P. Benzenesulfonyl compounds and the use thereof
US8765736B2 (en) 2007-09-28 2014-07-01 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
CN111620802A (zh) * 2020-06-18 2020-09-04 山西千岫制药有限公司 一种头孢托罗中间体(r)-1-苄基-3-氨基吡咯烷的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4785119A (en) * 1985-10-11 1988-11-15 Tokyo Kasei Kogyo Co., Ltd. 3-aminopyrrolidine compound and process for preparation thereof
US4851418A (en) * 1987-08-21 1989-07-25 Warner-Lambert Company Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent
US4859776A (en) * 1988-03-11 1989-08-22 Abbott Laboratories (S)-7-(3-aminopyrrolidin-1-yl)-1-(ortho, para-difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid and method for its preparation
JP2995704B2 (ja) * 1989-02-17 1999-12-27 東京化成工業株式会社 光学活性な１ｈ−３−アミノピロリジン化合物の製造法
US4916141A (en) * 1989-03-28 1990-04-10 Warner-Lambert Company (S)-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
HU208005B (en) * 1990-02-19 1993-07-28 Kyorin Seiyaku Kk Process for producing optically active 8-methoxy-quinolone-carboxylic acid derivatives and pharmaceutical compositions containing them
US5177217A (en) * 1992-04-27 1993-01-05 Warner-Lambert Company Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines

Also Published As

Publication number Publication date
NO944075L (no) 1994-12-27
GR3031149T3 (en) 1999-12-31
JP3264928B2 (ja) 2002-03-11
NO944075D0 (no) 1994-10-26
SK281195B6 (sk) 2001-01-18
US5177217A (en) 1993-01-05
DE69325452D1 (de) 1999-07-29
CA2133091C (en) 2005-01-04
HU220603B1 (hu) 2002-03-28
AU666736B2 (en) 1996-02-22
NO300969B1 (no) 1997-08-25
SK129894A3 (en) 1995-05-10
DE69325452T2 (de) 2000-05-18
RU94046013A (ru) 1996-10-10
FI106122B (fi) 2000-11-30
AU4289993A (en) 1993-11-29
ES2135477T3 (es) 1999-11-01
EP0638068A1 (de) 1995-02-15
CZ285593B6 (cs) 1999-09-15
EP0638068B1 (de) 1999-06-23
MX9302414A (es) 1993-10-01
DK0638068T3 (da) 1999-11-22
NZ252850A (en) 1996-10-28
WO1993022283A1 (en) 1993-11-11
FI945000A0 (fi) 1994-10-24
FI945000A (fi) 1994-10-24
JPH07506110A (ja) 1995-07-06
EP0911322A3 (de) 2001-06-13
EP0911322A2 (de) 1999-04-28
CZ257694A3 (en) 1995-10-18
CA2133091A1 (en) 1993-11-11
KR950701316A (ko) 1995-03-23
RU2101279C1 (ru) 1998-01-10
HUT70218A (en) 1995-09-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee