ES2135477T3 - Proceso de produccion de (s)-3-amino-1-pirrolidinas sustituidas. - Google Patents

Proceso de produccion de (s)-3-amino-1-pirrolidinas sustituidas.

Info

Publication number
ES2135477T3
ES2135477T3 ES93912301T ES93912301T ES2135477T3 ES 2135477 T3 ES2135477 T3 ES 2135477T3 ES 93912301 T ES93912301 T ES 93912301T ES 93912301 T ES93912301 T ES 93912301T ES 2135477 T3 ES2135477 T3 ES 2135477T3
Authority
ES
Spain
Prior art keywords
pirrolidinas
amino
substituted
production process
propionylaminoü
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93912301T
Other languages
English (en)
Inventor
Tung Van Le
F Gregory Spence
James Norton Wemple
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Application granted granted Critical
Publication of ES2135477T3 publication Critical patent/ES2135477T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/22—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

SE DESCRIBE UN NUEVO PROCESO PARA PREPARAR UNA PIRROLIDINA (S) 3 DIO ESENCIAL PREPARANDO QUINOLONA Y AGENTES ANTIBACTERIANOS DE NAFTIRIDONA DONDE LA POSICION 7ERAL ESTEREOESPECIFICA DE 3 ACIDO L-ASPARTICO INEXPANSIVO. EL ACIDO L-ASPARTICO ES CONVERTIDO AL DESEADO (S) TRANSFORMACION DE ALTO RENDIMIENTO DE UNA AZIRIDINA SUSTITUIDA.
ES93912301T 1992-04-27 1993-04-16 Proceso de produccion de (s)-3-amino-1-pirrolidinas sustituidas. Expired - Lifetime ES2135477T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/874,657 US5177217A (en) 1992-04-27 1992-04-27 Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines

Publications (1)

Publication Number Publication Date
ES2135477T3 true ES2135477T3 (es) 1999-11-01

Family

ID=25364272

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93912301T Expired - Lifetime ES2135477T3 (es) 1992-04-27 1993-04-16 Proceso de produccion de (s)-3-amino-1-pirrolidinas sustituidas.

Country Status (20)

Country Link
US (1) US5177217A (es)
EP (2) EP0911322A3 (es)
JP (1) JP3264928B2 (es)
KR (1) KR950701316A (es)
AT (1) ATE181549T1 (es)
AU (1) AU666736B2 (es)
CA (1) CA2133091C (es)
CZ (1) CZ285593B6 (es)
DE (1) DE69325452T2 (es)
DK (1) DK0638068T3 (es)
ES (1) ES2135477T3 (es)
FI (1) FI106122B (es)
GR (1) GR3031149T3 (es)
HU (1) HU220603B1 (es)
MX (1) MX9302414A (es)
NO (1) NO300969B1 (es)
NZ (1) NZ252850A (es)
RU (1) RU2101279C1 (es)
SK (1) SK281195B6 (es)
WO (1) WO1993022283A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5177217A (en) * 1992-04-27 1993-01-05 Warner-Lambert Company Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines
US5977381A (en) * 1998-01-12 1999-11-02 Hoffmann-La Roche Inc. Process for making 3-amino-pyrolidine derivatives
EP1138672A1 (en) * 1998-01-12 2001-10-04 Basilea Pharmaceutica AG Process for the preparation of 3-amino-pyrrolidine derivatives
AU6367399A (en) 1998-11-02 2000-05-22 Welfide Corporation Pyrrolidine compounds and medicinal utilization thereof
US6531594B2 (en) 2000-08-24 2003-03-11 Mitsubishi Chemical Corporation Process for producing 1H-3-aminopyrrolidine and derivatives thereof
JP4481659B2 (ja) 2002-03-29 2010-06-16 株式会社カネカ １−ベンジル−３−アミノピロリジンの光学純度向上方法及びそれに用いられる塩
WO2005035493A1 (ja) * 2003-10-08 2005-04-21 Teijin Pharma Limited アミノピロリジン誘導体の製造方法および中間体化合物
TW200630337A (en) 2004-10-14 2006-09-01 Euro Celtique Sa Piperidinyl compounds and the use thereof
US8247442B2 (en) 2006-03-29 2012-08-21 Purdue Pharma L.P. Benzenesulfonamide compounds and their use
TW200815353A (en) 2006-04-13 2008-04-01 Euro Celtique Sa Benzenesulfonamide compounds and their use
TW200812963A (en) 2006-04-13 2008-03-16 Euro Celtique Sa Benzenesulfonamide compounds and the use thereof
US8399486B2 (en) 2007-04-09 2013-03-19 Purdue Pharma L.P. Benzenesulfonyl compounds and the use thereof
WO2009040659A2 (en) 2007-09-28 2009-04-02 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
CN111620802A (zh) * 2020-06-18 2020-09-04 山西千岫制药有限公司 一种头孢托罗中间体(r)-1-苄基-3-氨基吡咯烷的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4785119A (en) * 1985-10-11 1988-11-15 Tokyo Kasei Kogyo Co., Ltd. 3-aminopyrrolidine compound and process for preparation thereof
US4851418A (en) * 1987-08-21 1989-07-25 Warner-Lambert Company Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent
US4859776A (en) * 1988-03-11 1989-08-22 Abbott Laboratories (S)-7-(3-aminopyrrolidin-1-yl)-1-(ortho, para-difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid and method for its preparation
JP2995704B2 (ja) * 1989-02-17 1999-12-27 東京化成工業株式会社 光学活性な１ｈ−３−アミノピロリジン化合物の製造法
US4916141A (en) * 1989-03-28 1990-04-10 Warner-Lambert Company (S)-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
HU208005B (en) * 1990-02-19 1993-07-28 Kyorin Seiyaku Kk Process for producing optically active 8-methoxy-quinolone-carboxylic acid derivatives and pharmaceutical compositions containing them
US5177217A (en) * 1992-04-27 1993-01-05 Warner-Lambert Company Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines

Also Published As

Publication number Publication date
AU4289993A (en) 1993-11-29
SK129894A3 (en) 1995-05-10
AU666736B2 (en) 1996-02-22
EP0911322A2 (en) 1999-04-28
NO300969B1 (no) 1997-08-25
HUT70218A (en) 1995-09-28
DE69325452T2 (de) 2000-05-18
KR950701316A (ko) 1995-03-23
EP0638068B1 (en) 1999-06-23
US5177217A (en) 1993-01-05
NZ252850A (en) 1996-10-28
RU94046013A (ru) 1996-10-10
CA2133091C (en) 2005-01-04
FI945000A (fi) 1994-10-24
DE69325452D1 (de) 1999-07-29
EP0638068A1 (en) 1995-02-15
CA2133091A1 (en) 1993-11-11
SK281195B6 (sk) 2001-01-18
ATE181549T1 (de) 1999-07-15
JP3264928B2 (ja) 2002-03-11
HU220603B1 (hu) 2002-03-28
FI106122B (fi) 2000-11-30
CZ257694A3 (en) 1995-10-18
DK0638068T3 (da) 1999-11-22
NO944075D0 (no) 1994-10-26
WO1993022283A1 (en) 1993-11-11
NO944075L (no) 1994-12-27
GR3031149T3 (en) 1999-12-31
CZ285593B6 (cs) 1999-09-15
EP0911322A3 (en) 2001-06-13
FI945000A0 (fi) 1994-10-24
RU2101279C1 (ru) 1998-01-10
MX9302414A (es) 1993-10-01
JPH07506110A (ja) 1995-07-06

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