MX383544B - Lisinas de bacteriofago de streptococcus para la deteccion y tratamiento de bacterias gram positivas - Google Patents
Lisinas de bacteriofago de streptococcus para la deteccion y tratamiento de bacterias gram positivasInfo
- Publication number
- MX383544B MX383544B MX2019015029A MX2019015029A MX383544B MX 383544 B MX383544 B MX 383544B MX 2019015029 A MX2019015029 A MX 2019015029A MX 2019015029 A MX2019015029 A MX 2019015029A MX 383544 B MX383544 B MX 383544B
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- positive bacteria
- streptococcus
- detection
- gram positive
- Prior art date
Links
- 241000194017 Streptococcus Species 0.000 title abstract 3
- 241000192125 Firmicutes Species 0.000 title abstract 2
- 241001515965 unidentified phage Species 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 241000191940 Staphylococcus Species 0.000 abstract 1
- 230000002101 lytic effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2462—Lysozyme (3.2.1.17)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/50—Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01017—Lysozyme (3.2.1.17)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161477836P | 2011-04-21 | 2011-04-21 | |
| PCT/US2012/034456 WO2012145630A2 (en) | 2011-04-21 | 2012-04-20 | Streptococcus bacteriophage lysins for detection and treatment of gram positive bacteria |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX383544B true MX383544B (es) | 2025-03-14 |
Family
ID=47042182
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019015029A MX383544B (es) | 2011-04-21 | 2012-04-20 | Lisinas de bacteriofago de streptococcus para la deteccion y tratamiento de bacterias gram positivas |
| MX2016000588A MX370442B (es) | 2011-04-21 | 2012-04-20 | Proteínas quiméricas de una lisina de bacteriófago de streptococcus para la detección y tratamiento de bacterias gram positivas. |
| MX2013012241A MX336427B (es) | 2011-04-21 | 2012-04-20 | Lisinas de bacteriofago de estreptococcus para la deteccion y tratamiento de bacterias gram positivas. |
| MX2021007008A MX2021007008A (es) | 2011-04-21 | 2013-10-18 | Lisinas de bacteriófago de streptococcus para la detección y tratamiento de bacterias gram positivas. |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016000588A MX370442B (es) | 2011-04-21 | 2012-04-20 | Proteínas quiméricas de una lisina de bacteriófago de streptococcus para la detección y tratamiento de bacterias gram positivas. |
| MX2013012241A MX336427B (es) | 2011-04-21 | 2012-04-20 | Lisinas de bacteriofago de estreptococcus para la deteccion y tratamiento de bacterias gram positivas. |
| MX2021007008A MX2021007008A (es) | 2011-04-21 | 2013-10-18 | Lisinas de bacteriófago de streptococcus para la detección y tratamiento de bacterias gram positivas. |
Country Status (12)
| Country | Link |
|---|---|
| US (7) | US9034322B2 (enExample) |
| EP (2) | EP3252155A1 (enExample) |
| JP (4) | JP6139509B2 (enExample) |
| CN (4) | CN103857410A (enExample) |
| AU (3) | AU2012245357B2 (enExample) |
| CA (1) | CA2833409A1 (enExample) |
| DK (1) | DK2699253T3 (enExample) |
| ES (1) | ES2682670T3 (enExample) |
| HK (2) | HK1244503A1 (enExample) |
| IL (4) | IL228869B (enExample) |
| MX (4) | MX383544B (enExample) |
| WO (1) | WO2012145630A2 (enExample) |
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| EP3252076B1 (en) | 2011-01-14 | 2019-09-04 | The Regents Of The University Of California | Diagnostic use of antibodies against ror-1 protein |
| JP2014519485A (ja) * | 2011-04-21 | 2014-08-14 | ユニベルシタイト ユトレヒト ホールディング ベーフェー | コンパニオン動物および家畜におけるグラム陽性細菌を処置するためのＳｔｒｅｐｔｏｃｏｃｃｕｓバクテリオファージリシン |
| NL2007038C2 (en) * | 2011-07-04 | 2013-01-07 | Vereniging Voor Christelijk Hoger Onderwijs | System and method for predicting the viability of a body tissue in a patient, and measuring device used therein. |
| US10813983B2 (en) | 2012-05-09 | 2020-10-27 | Contrafect Corporation | Bacteriophage lysin and antibiotic combinations against gram positive bacteria |
| KR20230135161A (ko) * | 2012-05-09 | 2023-09-22 | 콘트라펙트 코포레이션 | 박테리오파지 리신을 이용한 생물막의 예방, 붕괴 및 치료 |
| CN104073478A (zh) * | 2014-06-13 | 2014-10-01 | 上海交通大学 | 杀灭革兰氏阳性菌的酶抗生素及其制备、用途 |
| CN106659748B (zh) * | 2014-06-26 | 2021-08-31 | 洛克菲勒大学 | 不动杆菌属溶素 |
| CN104726439B (zh) * | 2015-04-13 | 2017-11-14 | 武汉菲吉乐科生物科技有限公司 | 一种广谱的链球菌裂解酶及其应用 |
| CN104805066B (zh) * | 2015-05-18 | 2018-04-24 | 武汉菲吉乐科生物科技有限公司 | 一种葡萄球菌裂解酶及其应用 |
| US20190008930A1 (en) * | 2015-07-31 | 2019-01-10 | The Regents Of The University Of California | Mycobacterium lysterase: a novel treatment for acne |
| EP3341013A4 (en) * | 2015-09-13 | 2018-07-18 | The Rockefeller University | Clostridium difficile BACTERIOPHAGE LYSINS FOR DETECTION AND TREATMENT OF Clostridium difficile BACTERIA INFECTION |
| CA2998484A1 (en) | 2015-09-17 | 2017-03-23 | Contrafect Corporation | Use of lysin to restore/augment antibacterial activity in the presence of pulmonary surfactant of antibiotics inhibited thereby |
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| EP3651739A4 (en) * | 2017-07-10 | 2021-04-07 | Contrafect Corporation | BLOOD COMPONENT POTENTIALIZATION OF LYTIC PROTEIN ANTIBACTERIAL ACTIVITY AND RELATED METHODS AND USES |
| MX2020006098A (es) | 2017-12-12 | 2020-08-24 | Contrafect Corp | Lisinas y sus derivados con actividad bactericida contra pseudomona aeruginosa, en la presencia de suero humano. |
| CN117866859A (zh) * | 2018-01-05 | 2024-04-12 | 阿兹特拉公司 | 葡萄球菌属细菌的营养缺陷型菌株 |
| CN112118861A (zh) * | 2018-02-26 | 2020-12-22 | 康特拉费克特公司 | 修饰的PlySs2溶素及其用途 |
| KR102073088B1 (ko) * | 2018-06-04 | 2020-02-04 | (주)인트론바이오테크놀로지 | 신규한 스트렙토코커스 수이스 박테리오파지 Str-SUP-2 및 이의 스트렙토코커스 수이스 균 증식 억제 용도 |
| KR102073086B1 (ko) * | 2018-06-04 | 2020-02-04 | (주)인트론바이오테크놀로지 | 신규한 스트렙토코커스 수이스 박테리오파지 Str-SUP-1 및 이의 스트렙토코커스 수이스 균 증식 억제 용도 |
| KR102073094B1 (ko) * | 2018-06-04 | 2020-02-04 | (주)인트론바이오테크놀로지 | 신규한 스트렙토코커스 수이스 박테리오파지 Str-SUP-3 및 이의 스트렙토코커스 수이스 균 증식 억제 용도 |
| CN112789350A (zh) * | 2018-08-17 | 2021-05-11 | 贝克顿·迪金森公司 | 利用微滴的抗微生物剂敏感性测试 |
| WO2020077286A1 (en) | 2018-10-12 | 2020-04-16 | Quidel Corporation | Extraction reagent for use in an assay for detection of group a streptococcus |
| WO2020198073A1 (en) * | 2019-03-22 | 2020-10-01 | Contrafect Corporation | Method of treating infective endocarditis |
| CN114040773A (zh) * | 2019-04-05 | 2022-02-11 | 康特拉费克特公司 | 在存在人血清的情况下对铜绿假单胞菌具有杀菌活性的溶素及其衍生物 |
| BR112021019884A2 (pt) * | 2019-04-11 | 2022-01-18 | Contrafect Corp | Método de tratamento e prevenção de infecções ósseas e articulares |
| JP2023526386A (ja) * | 2020-05-19 | 2023-06-21 | コントラフェクト コーポレイション | グラム陽性細菌に対して使用される修飾ＰｌｙＳｓ２溶解素及び抗生物質の組合せ |
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| CN114480299B (zh) * | 2020-10-27 | 2023-08-29 | 暨南大学 | 一种蜡样芽胞杆菌噬菌体及其应用 |
| MX2023006088A (es) * | 2020-11-25 | 2023-07-31 | Laboratory Corp America Holdings | Métodos y sistemas para la detección de microorganismos utilizando agentes infecciosos. |
| CN112760312B (zh) * | 2021-01-20 | 2022-06-17 | 华中农业大学 | 一种裂解革兰氏阳性菌的裂解酶plyssX609及其应用 |
| JP2024503809A (ja) * | 2021-01-25 | 2024-01-29 | アベイルズ メディカル，インコーポレイテッド | 曝気を用いて出力試料を準備する装置、システム、及び方法 |
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| KR102742550B1 (ko) * | 2022-07-26 | 2024-12-18 | 주식회사 인트론바이오테크놀로지 | 연쇄상구균에 대하여 용균 활성을 갖는 항균단백질 |
| EP4588068A1 (en) * | 2022-09-16 | 2025-07-23 | The Johns Hopkins University | Machine learning systems and related aspects for the detection of disease states |
| CN116640754B (zh) * | 2023-07-21 | 2023-10-10 | 临沂大学 | 一种链球菌前噬菌体裂解酶lys224及应用 |
| CN117965624B (zh) * | 2023-10-11 | 2024-12-17 | 圆因(北京)生物科技有限公司 | 一种用于编码耐甲氧西林金黄色葡萄球菌内溶素的线性dna、线性rna及其质粒表达载体 |
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| IE20060488A1 (en) * | 2006-06-29 | 2008-01-09 | Teagasc Agric Food Dev Authori | Recombinant staphylococcal phage lysin as an antibacterial agent |
| DE102006061002A1 (de) * | 2006-12-22 | 2008-06-26 | Profos Ag | Verfahren und Mittel zur Anreicherung, Entfernung und zum Nachweis von gram-positiven Bakterien |
| EP2225263A1 (en) | 2007-11-26 | 2010-09-08 | Plant Bioscience Limited | Novel polypeptides having endolysin activity and uses thereof |
| EP2103308A1 (de) * | 2008-03-20 | 2009-09-23 | PhytoLine GmbH | Verfahren zur Herstellung eines Gemisches von Bakteriophagen und deren Verwendung für die Therapie von Antibiotika-resistenten Staphylococcen |
| WO2010002959A2 (en) | 2008-07-03 | 2010-01-07 | The Rockefeller University | A chimeric bacteriophage lysin with activity against staphylococci bacteria |
| WO2010011960A2 (en) * | 2008-07-24 | 2010-01-28 | The United State Of America, As Represented By The Secretary Of Agriculture | Triple acting antimicrobials that are refractory to resistance development |
| GB0815484D0 (en) * | 2008-08-26 | 2008-10-01 | Univ Leuven Kath | Antibacterial agents |
| KR101016918B1 (ko) * | 2009-01-08 | 2011-02-25 | 주식회사 인트론바이오테크놀로지 | 박테리아 특이적 넓은 항균 활성을 갖는 신규한 리신 단백질 |
| EP2539446B1 (en) * | 2010-01-25 | 2017-11-01 | Alere Scarborough Inc. | A25 bacteriophage lysin |
| JP2014519485A (ja) * | 2011-04-21 | 2014-08-14 | ユニベルシタイト ユトレヒト ホールディング ベーフェー | コンパニオン動物および家畜におけるグラム陽性細菌を処置するためのＳｔｒｅｐｔｏｃｏｃｃｕｓバクテリオファージリシン |
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