MX2021007008A - Lisinas de bacteriófago de streptococcus para la detección y tratamiento de bacterias gram positivas. - Google Patents

Lisinas de bacteriófago de streptococcus para la detección y tratamiento de bacterias gram positivas.

Info

Publication number
MX2021007008A
MX2021007008A MX2021007008A MX2021007008A MX2021007008A MX 2021007008 A MX2021007008 A MX 2021007008A MX 2021007008 A MX2021007008 A MX 2021007008A MX 2021007008 A MX2021007008 A MX 2021007008A MX 2021007008 A MX2021007008 A MX 2021007008A
Authority
MX
Mexico
Prior art keywords
treatment
positive bacteria
detection
gram positive
streptococcus
Prior art date
Application number
MX2021007008A
Other languages
English (en)
Inventor
Vincent A Fischetti
Jonathan Schmitz
Daniel Gilmer
Chad Euler
Original Assignee
Univ Rockefeller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rockefeller filed Critical Univ Rockefeller
Publication of MX2021007008A publication Critical patent/MX2021007008A/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2462—Lysozyme (3.2.1.17)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/50—Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01017—Lysozyme (3.2.1.17)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención provee métodos, composiciones y artículos de fabricación útiles para el mejoramiento terapéutico y tratamiento de bacterias gram positivas, que incluyen Streptococcus y Staphylococcus, y afecciones relacionadas; la invención provee composiciones y métodos que incorporan y utilizan lisinas de bacteriófago derivadas de Streptococcus suis, particularmente las enzimas líticas PlySs2 y/o PlySs1, y variantes de las mismas que incluyen formas truncadas de las mismas. Se proveen métodos de tratamiento de humanos.
MX2021007008A 2011-04-21 2013-10-18 Lisinas de bacteriófago de streptococcus para la detección y tratamiento de bacterias gram positivas. MX2021007008A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161477836P 2011-04-21 2011-04-21

Publications (1)

Publication Number Publication Date
MX2021007008A true MX2021007008A (es) 2022-06-02

Family

ID=47042182

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2016000588A MX370442B (es) 2011-04-21 2012-04-20 Proteínas quiméricas de una lisina de bacteriófago de streptococcus para la detección y tratamiento de bacterias gram positivas.
MX2013012241A MX336427B (es) 2011-04-21 2012-04-20 Lisinas de bacteriofago de estreptococcus para la deteccion y tratamiento de bacterias gram positivas.
MX2021007008A MX2021007008A (es) 2011-04-21 2013-10-18 Lisinas de bacteriófago de streptococcus para la detección y tratamiento de bacterias gram positivas.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
MX2016000588A MX370442B (es) 2011-04-21 2012-04-20 Proteínas quiméricas de una lisina de bacteriófago de streptococcus para la detección y tratamiento de bacterias gram positivas.
MX2013012241A MX336427B (es) 2011-04-21 2012-04-20 Lisinas de bacteriofago de estreptococcus para la deteccion y tratamiento de bacterias gram positivas.

Country Status (12)

Country Link
US (7) US9034322B2 (es)
EP (2) EP2699253B1 (es)
JP (4) JP6139509B2 (es)
CN (4) CN103857410A (es)
AU (3) AU2012245357B2 (es)
CA (1) CA2833409A1 (es)
DK (1) DK2699253T3 (es)
ES (1) ES2682670T3 (es)
HK (2) HK1244503A1 (es)
IL (4) IL228869B (es)
MX (3) MX370442B (es)
WO (1) WO2012145630A2 (es)

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Also Published As

Publication number Publication date
US20230167427A9 (en) 2023-06-01
NZ731111A (en) 2019-06-28
US20220064615A1 (en) 2022-03-03
JP2019022504A (ja) 2019-02-14
IL287530A (en) 2021-12-01
CN103857410A (zh) 2014-06-11
JP6735796B2 (ja) 2020-08-05
US20200149025A1 (en) 2020-05-14
US20200002694A1 (en) 2020-01-02
EP3252155A1 (en) 2017-12-06
IL266476A (en) 2019-06-30
HK1247956A1 (zh) 2018-10-05
NZ616945A (en) 2015-11-27
WO2012145630A3 (en) 2014-05-01
WO2012145630A2 (en) 2012-10-26
IL266476B (en) 2020-01-30
US20140072549A1 (en) 2014-03-13
IL228869B (en) 2019-05-30
JP6139509B2 (ja) 2017-05-31
MX370442B (es) 2019-12-13
CN115887627A (zh) 2023-04-04
CA2833409A1 (en) 2012-10-26
AU2012245357A1 (en) 2013-11-14
IL228869A0 (en) 2013-12-31
US11155799B2 (en) 2021-10-26
US11111484B2 (en) 2021-09-07
JP6587655B2 (ja) 2019-10-09
AU2012245357B2 (en) 2017-06-08
IL271300A (en) 2020-01-30
AU2017202728B2 (en) 2019-04-04
US9034322B2 (en) 2015-05-19
NZ713076A (en) 2017-05-26
US20150267185A1 (en) 2015-09-24
EP2699253B1 (en) 2018-03-28
JP2014518849A (ja) 2014-08-07
CN107189997A (zh) 2017-09-22
AU2019204660B2 (en) 2021-01-28
DK2699253T3 (en) 2018-07-16
US20220127590A1 (en) 2022-04-28
IL271300B (en) 2021-12-01
JP2016147903A (ja) 2016-08-18
US9914915B2 (en) 2018-03-13
HK1244503A1 (zh) 2018-08-10
EP2699253A4 (en) 2015-07-01
MX336427B (es) 2016-01-18
MX2013012241A (es) 2014-05-07
US10544407B2 (en) 2020-01-28
AU2019204660A1 (en) 2019-07-18
CN108578685A (zh) 2018-09-28
ES2682670T3 (es) 2018-09-21
EP2699253A2 (en) 2014-02-26
US20170298334A1 (en) 2017-10-19
JP6284976B2 (ja) 2018-02-28
JP2017171686A (ja) 2017-09-28
AU2017202728A1 (en) 2017-05-18

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