MX382902B - Inhibidor de la vía noth en combinación con un agente inmunoterapéutico para usarse en el tratamiento de cáncer. - Google Patents

Inhibidor de la vía noth en combinación con un agente inmunoterapéutico para usarse en el tratamiento de cáncer.

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Publication number
MX382902B
MX382902B MX2017005258A MX2017005258A MX382902B MX 382902 B MX382902 B MX 382902B MX 2017005258 A MX2017005258 A MX 2017005258A MX 2017005258 A MX2017005258 A MX 2017005258A MX 382902 B MX382902 B MX 382902B
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MX
Mexico
Prior art keywords
cancer
combination
treatment
noth
pathway inhibitor
Prior art date
Application number
MX2017005258A
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English (en)
Other versions
MX2017005258A (es
Inventor
Autisn L Gurney
Christopher Lamond Murriel
Inkyung Park
Jakob Dupont
Julie Michelle Roda
Minu K Srivastava
Timothy Charles Hoey
Original Assignee
Oncomed Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncomed Pharm Inc filed Critical Oncomed Pharm Inc
Publication of MX2017005258A publication Critical patent/MX2017005258A/es
Publication of MX382902B publication Critical patent/MX382902B/es

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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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Abstract

La presente invención proporciona métodos que comprenden terapia combinada para la modulación de respuestas inmunitarias, para inhibir el crecimiento del tumor, y/o para tratar cáncer. En particular, la presente invención proporcionar inhibidores de trayectoria Notch en combinación con agentes inmunoterapéuticos para el tratamiento de cáncer y otras enfermedades.
MX2017005258A 2014-10-31 2015-10-30 Inhibidor de la vía noth en combinación con un agente inmunoterapéutico para usarse en el tratamiento de cáncer. MX382902B (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462073634P 2014-10-31 2014-10-31
US201562127172P 2015-03-02 2015-03-02
US201562192133P 2015-07-14 2015-07-14
US201562242567P 2015-10-16 2015-10-16
PCT/US2015/058327 WO2016070051A2 (en) 2014-10-31 2015-10-30 Combination therapy for treatment of disease

Publications (2)

Publication Number Publication Date
MX2017005258A MX2017005258A (es) 2017-07-26
MX382902B true MX382902B (es) 2025-03-13

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Application Number Title Priority Date Filing Date
MX2017005258A MX382902B (es) 2014-10-31 2015-10-30 Inhibidor de la vía noth en combinación con un agente inmunoterapéutico para usarse en el tratamiento de cáncer.

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US (4) US20160176962A1 (es)
EP (1) EP3212233B1 (es)
JP (1) JP6827415B2 (es)
CN (1) CN107530419B (es)
AU (1) AU2015338974B2 (es)
CA (1) CA2966042A1 (es)
DK (1) DK3212233T3 (es)
ES (1) ES2808153T3 (es)
MX (1) MX382902B (es)
PT (1) PT3212233T (es)
WO (1) WO2016070051A2 (es)

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