MX382776B - Uso de levocetirizina y montelukast en el tratamiento de lesion traumatica. - Google Patents
Uso de levocetirizina y montelukast en el tratamiento de lesion traumatica.Info
- Publication number
- MX382776B MX382776B MX2015012315A MX2015012315A MX382776B MX 382776 B MX382776 B MX 382776B MX 2015012315 A MX2015012315 A MX 2015012315A MX 2015012315 A MX2015012315 A MX 2015012315A MX 382776 B MX382776 B MX 382776B
- Authority
- MX
- Mexico
- Prior art keywords
- levocetirizine
- montelukast
- formulations
- methods
- treatment
- Prior art date
Links
- ZKLPARSLTMPFCP-OAQYLSRUSA-N 2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]-1-piperazinyl]ethoxy]acetic acid Chemical compound C1CN(CCOCC(=O)O)CCN1[C@@H](C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 ZKLPARSLTMPFCP-OAQYLSRUSA-N 0.000 title abstract 2
- UCHDWCPVSPXUMX-TZIWLTJVSA-N Montelukast Chemical compound CC(C)(O)C1=CC=CC=C1CC[C@H](C=1C=C(\C=C\C=2N=C3C=C(Cl)C=CC3=CC=2)C=CC=1)SCC1(CC(O)=O)CC1 UCHDWCPVSPXUMX-TZIWLTJVSA-N 0.000 title abstract 2
- 229960001508 levocetirizine Drugs 0.000 title abstract 2
- 229960005127 montelukast Drugs 0.000 title abstract 2
- 208000014674 injury Diseases 0.000 title 1
- 230000008736 traumatic injury Effects 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- 208000004852 Lung Injury Diseases 0.000 abstract 1
- 206010069363 Traumatic lung injury Diseases 0.000 abstract 1
- 208000029028 brain injury Diseases 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 210000004072 lung Anatomy 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- A—HUMAN NECESSITIES
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
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- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/5375—1,4-Oxazines, e.g. morpholine
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- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
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- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
Abstract
Las modalidades descritas en la presente incluyen métodos y formulaciones para tratar lesión pulmonar y cerebral. Los métodos y formulaciones incluyen, pero no se limitan a, método y formulaciones para administrar concentraciones efectivas de levocetirizina y montelukast a un paciente en necesidad. Los métodos y formulaciones pueden comprender elementos convencionales y/o de liberación modificada, proporcionando la administración del fármaco al paciente.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361780336P | 2013-03-13 | 2013-03-13 | |
| PCT/US2014/021706 WO2014164282A1 (en) | 2013-03-13 | 2014-03-07 | Use of levocetirizine and montelukast in the treatment of traumatic injury |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015012315A MX2015012315A (es) | 2015-12-16 |
| MX382776B true MX382776B (es) | 2025-03-13 |
Family
ID=51658846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015012315A MX382776B (es) | 2013-03-13 | 2014-03-07 | Uso de levocetirizina y montelukast en el tratamiento de lesion traumatica. |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US9522148B2 (es) |
| EP (2) | EP2969002B8 (es) |
| JP (1) | JP6313414B2 (es) |
| KR (1) | KR20150135339A (es) |
| CN (1) | CN105517631A (es) |
| AU (1) | AU2014249531B2 (es) |
| CA (1) | CA2901410C (es) |
| ES (2) | ES2770760T3 (es) |
| HK (1) | HK1222818A1 (es) |
| MX (1) | MX382776B (es) |
| RU (1) | RU2672871C2 (es) |
| WO (1) | WO2014164282A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9044479B2 (en) | 2010-06-16 | 2015-06-02 | Bruce Chandler May | Use of levocetirizine and montelukast in the treatment of influenza, common cold and inflammation |
| AU2014249531B2 (en) * | 2013-03-13 | 2018-11-29 | IRR, Inc. | Use of levocetirizine and montelukast in the treatment of traumatic injury |
| JP2016512262A (ja) | 2013-03-13 | 2016-04-25 | インフラマトリー・レスポンス・リサーチ・インコーポレイテッド | 血管炎の処置におけるレボセチリジン及びモンテルカストの使用 |
| ES2745041T3 (es) | 2013-03-13 | 2020-02-27 | Inflammatory Response Res Inc | Uso de levocetirizina y montelukast en el tratamiento de trastornos autoinmunitarios |
| JP2017526728A (ja) | 2014-09-15 | 2017-09-14 | インフラマトリー・レスポンス・リサーチ・インコーポレイテッド | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
| WO2017210417A1 (en) * | 2016-06-03 | 2017-12-07 | Inflammatory Response Research, Inc. | Levocetirizine and montelukast in the treatment of radiation-mediated conditions |
| CN110312513B (zh) * | 2017-07-05 | 2022-07-08 | 艾缇亚(上海)制药有限公司 | 包含孟鲁司特与贻贝粘附蛋白的组合的局部制剂 |
| WO2021236518A1 (en) * | 2020-05-19 | 2021-11-25 | IRR, Inc. | Levocetirizine and montelukast in the treatment of sepsis and symptoms thereof |
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| US4801612A (en) | 1986-07-03 | 1989-01-31 | Regents Of The University Of California | Method of inhibiting inflammatory response |
| US5211958A (en) | 1987-11-30 | 1993-05-18 | Gist-Brocades, N.V. | Pharmaceutical composition and process for its preparation |
| US5147637A (en) * | 1988-06-07 | 1992-09-15 | The Rockefeller University | Method of inhibiting the influx of leukocytes into organs during sepsis or other trauma |
| EP0808636A1 (en) * | 1991-11-14 | 1997-11-26 | Alliance Pharmaceutical Corporation | Method for partial liquid ventilation using fluorocarbons |
| WO1995009652A1 (en) | 1993-10-06 | 1995-04-13 | The Kennedy Institute For Rheumatology | Treatment of autoimmune and inflammatory disorders |
| HUP0001960A2 (hu) | 1997-01-24 | 2000-10-28 | Autoimmune, Inc. | Metotrexát kombináció autoimmun tünetek befolyásolására |
| PL193131B1 (pl) | 1997-12-23 | 2007-01-31 | Schering Corp | Kompozycja farmaceutyczna zawierająca kombinację składników aktywnych i jej zastosowanie |
| WO1999037155A1 (en) * | 1998-01-27 | 1999-07-29 | Nutramax Laboratories, Inc. | Combinations of tyrosine, methylating agents, phospholipids, fatty acids, and st. john's wort for the treatment of mental disturbances |
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| HU224941B1 (en) | 2001-08-10 | 2006-04-28 | Bgi Innovacios Kft | Phototerapy apparatus |
| WO2003101434A2 (en) | 2001-12-21 | 2003-12-11 | Sampad Bhattacharya | Intranasal pharmaceutical compositions comprising an antihistamine and a leukotriene inhibitor |
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-
2014
- 2014-03-07 AU AU2014249531A patent/AU2014249531B2/en active Active
- 2014-03-07 MX MX2015012315A patent/MX382776B/es unknown
- 2014-03-07 KR KR1020157027768A patent/KR20150135339A/ko not_active Ceased
- 2014-03-07 ES ES17205910T patent/ES2770760T3/es active Active
- 2014-03-07 ES ES14779507.4T patent/ES2660494T3/es active Active
- 2014-03-07 HK HK16111011.4A patent/HK1222818A1/zh unknown
- 2014-03-07 CN CN201480013699.3A patent/CN105517631A/zh active Pending
- 2014-03-07 EP EP14779507.4A patent/EP2969002B8/en active Active
- 2014-03-07 EP EP17205910.7A patent/EP3308835B1/en active Active
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- 2014-03-07 JP JP2016500815A patent/JP6313414B2/ja active Active
- 2014-03-07 RU RU2015134421A patent/RU2672871C2/ru active
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2015
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Also Published As
| Publication number | Publication date |
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| JP2016516033A (ja) | 2016-06-02 |
| EP3308835A1 (en) | 2018-04-18 |
| RU2015134421A (ru) | 2017-04-19 |
| WO2014164282A1 (en) | 2014-10-09 |
| RU2015134421A3 (es) | 2018-03-19 |
| CN105517631A (zh) | 2016-04-20 |
| US20170056395A1 (en) | 2017-03-02 |
| RU2672871C2 (ru) | 2018-11-20 |
| JP6313414B2 (ja) | 2018-04-18 |
| US9937166B2 (en) | 2018-04-10 |
| US11103500B2 (en) | 2021-08-31 |
| EP2969002B1 (en) | 2018-01-10 |
| CA2901410C (en) | 2023-09-12 |
| KR20150135339A (ko) | 2015-12-02 |
| AU2014249531A1 (en) | 2015-08-27 |
| EP2969002A4 (en) | 2016-08-31 |
| EP2969002A1 (en) | 2016-01-20 |
| EP3308835B1 (en) | 2020-01-01 |
| AU2014249531B2 (en) | 2018-11-29 |
| US20220096465A1 (en) | 2022-03-31 |
| ES2660494T8 (es) | 2018-04-19 |
| US20150352104A1 (en) | 2015-12-10 |
| ES2660494T3 (es) | 2018-03-22 |
| EP2969002B8 (en) | 2018-02-21 |
| CA2901410A1 (en) | 2014-10-09 |
| ES2770760T3 (es) | 2020-07-03 |
| US9522148B2 (en) | 2016-12-20 |
| HK1222818A1 (zh) | 2017-07-14 |
| US20180185357A1 (en) | 2018-07-05 |
| MX2015012315A (es) | 2015-12-16 |
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