RU2015134421A - Применение левоцетиризина и монтелукаста при лечении травматических повреждений - Google Patents

Применение левоцетиризина и монтелукаста при лечении травматических повреждений Download PDF

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RU2015134421A
RU2015134421A RU2015134421A RU2015134421A RU2015134421A RU 2015134421 A RU2015134421 A RU 2015134421A RU 2015134421 A RU2015134421 A RU 2015134421A RU 2015134421 A RU2015134421 A RU 2015134421A RU 2015134421 A RU2015134421 A RU 2015134421A
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traumatic injury
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RU2015134421A
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Брюс Чендлер МЭЙ
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Инфламматори Респонс Ресёрч, Инк.
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
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Claims (14)

1. Способ лечения травматического повреждения или симптома травматического повреждения у нуждающегося в этом пациента, включающий введение эффективного количества комбинации левоцетиризина и монтелукаста.
2. Способ по п. 1, отличающийся тем, что травматическое повреждение представляет собой повреждение легкого.
3. Способ по п. 1, отличающийся тем, что симптом травматического повреждения представляет собой симптом повреждения легкого.
4. Способ по п. 1, отличающийся тем, что травматическое повреждение представляет собой повреждение мозга.
5. Способ по п. 1, отличающийся тем, что симптом травматического повреждения представляет собой симптом повреждения мозга.
6. Способ по любому из пп. 1-5, отличающийся тем, что указанную комбинацию вводят при возникновении симптомов.
7. Способ по любому из пп. 1-5, отличающийся тем, что указанную комбинацию вводят при постановке диагноза.
8. Способ по любому из пп. 1-5, отличающийся тем, что указанную комбинацию вводят последовательным образом.
9. Способ по любому из пп. 1-5, отличающийся тем, что указанную комбинацию вводятся по существу одновременно.
10. Способ по любому из пп. 1-5, дополнительно включающий введение дополнительного активного агента.
11. Способ по п. 10, отличающийся тем, что указанный дополнительный активный агент выбран из группы, состоящей из антибиотика, противовирусного, противопаразитарного, противогрибкового, вазопрессорного, диуретического агентов, антикоагулянта, противосудорожного лекарственного средства, ингибитора протонного насоса, антагониста H2-рецепторов, антипиретического агента, противовоспалительного лекарственного средства, антинеопластического лекарственного средства и их комбинаций.
12. Способ по п. 11, отличающийся тем, что указанный антибиотик включает ванкомицин, меропенем, амоксициллин/бета клаувулановую кислоту, левофлоксацин, пирперациллин/тазобактам, цефтриаксон, клиндамицин, азитромицин, триметоприм/сульфаметоксазол, доксициклин или их комбинации.
13. Способ по любому из пп. 1-5, отличающийся тем, что указанную комбинацию вводят пациенту одним или более путей из группы, состоящей из энтерального, внутривенного, внутрибрюшинного, ингаляционного, внутримышечного, подкожного и перорального путей.
14. Способ по любому из пп. 1-5, отличающийся тем, что левоцитиризин и монтелукаст вводят одинаковым путем.
RU2015134421A 2013-03-13 2014-03-07 Применение левоцетиризина и монтелукаста при лечении травматических повреждений RU2672871C2 (ru)

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US201361780336P 2013-03-13 2013-03-13
US61/780,336 2013-03-13
PCT/US2014/021706 WO2014164282A1 (en) 2013-03-13 2014-03-07 Use of levocetirizine and montelukast in the treatment of traumatic injury

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RU2015134421A3 RU2015134421A3 (ru) 2018-03-19
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JP (1) JP6313414B2 (ru)
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