MX2010004563A - Composiciones y métodos para modular la transducción de la señal intracelular mediada por la membrana celular. - Google Patents
Composiciones y métodos para modular la transducción de la señal intracelular mediada por la membrana celular.Info
- Publication number
- MX2010004563A MX2010004563A MX2010004563A MX2010004563A MX2010004563A MX 2010004563 A MX2010004563 A MX 2010004563A MX 2010004563 A MX2010004563 A MX 2010004563A MX 2010004563 A MX2010004563 A MX 2010004563A MX 2010004563 A MX2010004563 A MX 2010004563A
- Authority
- MX
- Mexico
- Prior art keywords
- membrane
- compositions
- methods
- signal transduction
- receptors
- Prior art date
Links
- 239000012528 membrane Substances 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 5
- 230000001413 cellular effect Effects 0.000 title abstract 2
- 230000031146 intracellular signal transduction Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000001404 mediated effect Effects 0.000 title 1
- 108090000045 G-Protein-Coupled Receptors Proteins 0.000 abstract 2
- 102000003688 G-Protein-Coupled Receptors Human genes 0.000 abstract 2
- 108010052285 Membrane Proteins Proteins 0.000 abstract 2
- 108020004084 membrane receptors Proteins 0.000 abstract 2
- 102000005962 receptors Human genes 0.000 abstract 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- 108091006027 G proteins Proteins 0.000 abstract 1
- 102000030782 GTP binding Human genes 0.000 abstract 1
- 108091000058 GTP-Binding Proteins 0.000 abstract 1
- 102000004310 Ion Channels Human genes 0.000 abstract 1
- 108090000862 Ion Channels Proteins 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 238000011284 combination treatment Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000003834 intracellular effect Effects 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
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Abstract
Aspectos particulares de la presente invención proporcionan composiciones y métodos para modular la transducción de la señal intracelular, incluyendo la modulación de al menos uno de la estructura de la membrana, el potencial de la membrana o la conductividad de la membrana, los receptores o las proteínas de la membrana, los canales de iones, y los sistemas de envío de mensajes celulares dependientes del calcio, que comprenden el uso de las soluciones inventivas, electrocinéticamente generadas, para impartir cambios electroquímicos y/o de conformación en las estructuras membranosas (por ejemplo, la membrana y/o las proteínas de la membrana, los receptores u otros componentes) incluyendo pero no limitado a receptores acoplados a la proteína G (GPCRs) y/o proteínas G, y uniones intracelulares. En las modalidades particulares, las soluciones o composiciones electrocinéticamente generadas son enriquecidas en gas y/o comprenden otros agentes terapéuticos. Otras modalidades incluyen métodos terapéuticos particulares que comprenden la administración o las formulaciones de las composiciones terapéuticas, y en varios tratamientos de combinación.
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98271907P | 2007-10-25 | 2007-10-25 | |
US98272007P | 2007-10-25 | 2007-10-25 | |
PCT/US2007/082578 WO2008052143A2 (en) | 2006-10-25 | 2007-10-25 | Mixing device and output fluids of same |
PCT/US2007/082581 WO2008115290A2 (en) | 2006-10-25 | 2007-10-25 | Methods of wound care and treatment |
PCT/US2007/082580 WO2008052145A2 (en) | 2006-10-25 | 2007-10-25 | Methods of therapeutic treatment of eyes and other human tissues using an oxygen-enriched solution |
US4834008P | 2008-04-28 | 2008-04-28 | |
US4834708P | 2008-04-28 | 2008-04-28 | |
US4833208P | 2008-04-28 | 2008-04-28 | |
US4840408P | 2008-04-28 | 2008-04-28 | |
PCT/US2008/081021 WO2009055614A1 (en) | 2007-10-25 | 2008-10-23 | Compositions and methods for modulating cellular membrane-mediated intracellular signal transduction |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010004563A true MX2010004563A (es) | 2010-07-28 |
Family
ID=42261767
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010004563A MX2010004563A (es) | 2007-10-25 | 2008-10-23 | Composiciones y métodos para modular la transducción de la señal intracelular mediada por la membrana celular. |
MX2010004554A MX2010004554A (es) | 2007-10-25 | 2008-10-24 | Composiciones y métodos para el tratamiento de inflamación. |
MX2010004564A MX2010004564A (es) | 2007-10-25 | 2008-10-24 | Composiciones y métodos para tratamiento de fibrosis quística. |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010004554A MX2010004554A (es) | 2007-10-25 | 2008-10-24 | Composiciones y métodos para el tratamiento de inflamación. |
MX2010004564A MX2010004564A (es) | 2007-10-25 | 2008-10-24 | Composiciones y métodos para tratamiento de fibrosis quística. |
Country Status (8)
Country | Link |
---|---|
EP (3) | EP2215260A4 (es) |
JP (6) | JP5613565B2 (es) |
CN (5) | CN101910412B (es) |
AU (3) | AU2008316794B2 (es) |
CA (3) | CA2703672A1 (es) |
IL (3) | IL205318A (es) |
MX (3) | MX2010004563A (es) |
WO (1) | WO2009055614A1 (es) |
Families Citing this family (27)
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US6702949B2 (en) | 1997-10-24 | 2004-03-09 | Microdiffusion, Inc. | Diffuser/emulsifier for aquaculture applications |
JP5595041B2 (ja) | 2006-10-25 | 2014-09-24 | リバルシオ コーポレイション | 酸素富化溶液を用いる、眼および他のヒト組織の治療処置の方法 |
US8445546B2 (en) | 2006-10-25 | 2013-05-21 | Revalesio Corporation | Electrokinetically-altered fluids comprising charge-stabilized gas-containing nanostructures |
EP3170401B1 (en) | 2006-10-25 | 2019-06-05 | Revalesio Corporation | Ionic aqueous fluid composition containing oxygen microbubbles |
US9523090B2 (en) | 2007-10-25 | 2016-12-20 | Revalesio Corporation | Compositions and methods for treating inflammation |
CN101910412B (zh) * | 2007-10-25 | 2013-08-21 | 利发利希奥公司 | 调节细胞膜介导的细胞内信号转导的组合物和方法 |
US10125359B2 (en) | 2007-10-25 | 2018-11-13 | Revalesio Corporation | Compositions and methods for treating inflammation |
MX2010004549A (es) * | 2007-10-25 | 2010-07-28 | Revalesio Corp | Composiciones y métodos bacteriostáticos o bactericidas. |
US9745567B2 (en) | 2008-04-28 | 2017-08-29 | Revalesio Corporation | Compositions and methods for treating multiple sclerosis |
CA2722658C (en) * | 2008-04-28 | 2018-09-18 | Richard L. Watson | Compositions and methods for treating multiple sclerosis |
EP2285347A4 (en) | 2008-05-01 | 2011-09-21 | Revalesio Corp | COMPOSITIONS AND METHODS OF TREATING DISORDERS OF THE DIGESTION SYSTEM |
BRPI0920430A2 (pt) * | 2008-10-22 | 2019-09-24 | Revalesio Corp | composições e métodos para tratar condições mediadas por metaloproteinase matriz 9 (mmp9) |
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