MX380149B - Metodo para la inactivación continua de un virus en un microreactor - Google Patents

Metodo para la inactivación continua de un virus en un microreactor

Info

Publication number
MX380149B
MX380149B MX2017013893A MX2017013893A MX380149B MX 380149 B MX380149 B MX 380149B MX 2017013893 A MX2017013893 A MX 2017013893A MX 2017013893 A MX2017013893 A MX 2017013893A MX 380149 B MX380149 B MX 380149B
Authority
MX
Mexico
Prior art keywords
virus
microreactor
product stream
segmented
continuous
Prior art date
Application number
MX2017013893A
Other languages
English (en)
Spanish (es)
Other versions
MX2017013893A (es
Inventor
Andrea Vester
Martin Lobedann
Peter Schwan
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MX2017013893A publication Critical patent/MX2017013893A/es
Publication of MX380149B publication Critical patent/MX380149B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0035—Gamma radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0094—Gaseous substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/04—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08—Radiation
    • A61L2/10—Ultraviolet radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20—Targets to be treated
    • A61L2202/21—Pharmaceuticals, e.g. medicaments, artificial body parts

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
MX2017013893A 2015-04-28 2016-04-25 Metodo para la inactivación continua de un virus en un microreactor MX380149B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15165505.7A EP3088006A1 (de) 2015-04-28 2015-04-28 Verfahren zur kontinuierlichen virusinaktivierung in einem mikroreaktor
PCT/EP2016/059169 WO2016173982A1 (de) 2015-04-28 2016-04-25 Verfahren zur kontinuierlichen virusinaktivierung in einem mikroreaktor

Publications (2)

Publication Number Publication Date
MX2017013893A MX2017013893A (es) 2018-03-15
MX380149B true MX380149B (es) 2025-03-12

Family

ID=53016520

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017013893A MX380149B (es) 2015-04-28 2016-04-25 Metodo para la inactivación continua de un virus en un microreactor

Country Status (20)

Country Link
US (1) US10434201B2 (enExample)
EP (2) EP3088006A1 (enExample)
JP (1) JP6851981B2 (enExample)
KR (1) KR20170140219A (enExample)
CN (1) CN107624073B (enExample)
AR (1) AR104440A1 (enExample)
AU (1) AU2016254582C1 (enExample)
BR (1) BR112017023246B1 (enExample)
CA (1) CA2983884A1 (enExample)
DK (1) DK3288596T3 (enExample)
ES (1) ES2720034T3 (enExample)
IL (1) IL255137B (enExample)
MX (1) MX380149B (enExample)
RU (1) RU2719363C2 (enExample)
SA (1) SA517390240B1 (enExample)
SG (1) SG11201708749WA (enExample)
TR (1) TR201904906T4 (enExample)
TW (1) TWI695070B (enExample)
WO (1) WO2016173982A1 (enExample)
ZA (1) ZA201708043B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102286411B1 (ko) * 2017-05-11 2021-08-05 이엠디 밀리포어 코포레이션 연속 유동 시스템에서 좁은 체류 시간 분포를 유지하기 위한 방법
US11732003B2 (en) 2017-05-11 2023-08-22 Emd Millipore Corporation Mechanical method of maintaining narrow residence time distributions in continuous flow systems
EP3651811A1 (en) 2017-07-10 2020-05-20 Baxalta Incorporated Method for incubating liquids and inactivating viruses
CA3115253A1 (en) * 2018-10-08 2020-04-16 Boehringer Ingelheim International Gmbh A novel continuous flow reactor for low ph viral inactivation
DE102018009597A1 (de) 2018-12-07 2020-06-10 Sartorius Stedim Biotech Gmbh Vorrichtung und Verfahren zur mehrfachen Änderung der Zusammensetzung eines Fluids
CN114247395B (zh) * 2020-09-23 2023-04-25 中国科学院大连化学物理研究所 一种中空纤维膜式微通道反应器及应用
GB2631765A (en) 2023-07-13 2025-01-15 Univ Cranfield Viral inactivation reactor and method
CN117298304B (zh) * 2023-09-18 2025-08-22 浙江大学 一种组装式连续病毒灭活装置及其设计方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4260877B2 (ja) * 1992-03-02 2009-04-30 バイオエング・インコーポレーテッド ウイルスの不活性化方法
EP0912238B1 (en) 1996-07-15 2001-10-10 CalCiTech Ltd. Production of powders
GB2359765B (en) * 2000-03-02 2003-03-05 Univ Newcastle Capillary reactor distribution device and method
DE10056096A1 (de) 2000-11-13 2002-06-13 Bayer Ag Vorrichtung zur Bestrahlung von Flüssigkeiten
EP1337280B1 (en) 2000-11-13 2013-09-04 Bayer Intellectual Property GmbH Method of inactivating microorganisms in a fluid using ultraviolet radiation
DE10312765A1 (de) * 2003-03-21 2004-09-30 Bayer Technology Services Gmbh Vorrichtung und Verfahren zur Sterilisation flüssiger Medien mittels UV-Bestrahlung und Kurzzeiterhitzung
WO2004103539A2 (en) * 2003-05-16 2004-12-02 Velocys Inc. Process for forming an emulsion using microchannel process technology
US7485671B2 (en) * 2003-05-16 2009-02-03 Velocys, Inc. Process for forming an emulsion using microchannel process technology
US7993580B2 (en) * 2004-08-24 2011-08-09 Baxter International Inc. Methods for the inactivation of microorganisms in biological fluids, flow through reactors and methods of controlling the light sum dose to effectively inactivate microorganisms in batch reactors
CN102513170B (zh) * 2004-09-09 2015-03-25 居里研究所 用于在微容器特别是微通道中操纵小包的装置
US7622509B2 (en) * 2004-10-01 2009-11-24 Velocys, Inc. Multiphase mixing process using microchannel process technology
CN1786018B (zh) * 2005-12-12 2011-06-22 天津协和生物科技发展有限公司 高纯度血红蛋白的分离纯化与病毒灭活工艺
DE102006019242A1 (de) 2006-04-21 2007-10-25 Bayer Technology Services Gmbh Prozessanalysensystem mit steriler Probenahme von mechanisch empfindlichem Material aus einem Bioreaktor
KR20100057597A (ko) * 2007-08-10 2010-05-31 가부시키가이샤 니혼포토사이언스 단파장 자외선 방전등과 자외선 조사 처리 장치
US8187554B2 (en) * 2008-04-23 2012-05-29 Microfluidics International Corporation Apparatus and methods for nanoparticle generation and process intensification of transport and reaction systems
NZ592097A (en) * 2008-10-20 2013-01-25 Abbott Lab Viral inactivation during purification of il-12 and il-18 antibodies
US8956566B2 (en) * 2012-03-12 2015-02-17 Pure Biosolutions, Llc System and method for virus inactivation
EP2918294A1 (de) * 2014-03-11 2015-09-16 Bayer Technology Services GmbH Vorrichtung und Verfahren zur kontinuierlichen Virusinaktivierung

Also Published As

Publication number Publication date
AU2016254582A1 (en) 2017-11-09
AU2016254582C1 (en) 2020-04-30
DK3288596T3 (da) 2019-05-06
TWI695070B (zh) 2020-06-01
US10434201B2 (en) 2019-10-08
TR201904906T4 (tr) 2019-05-21
TW201702377A (zh) 2017-01-16
EP3288596B1 (de) 2019-03-20
EP3288596A1 (de) 2018-03-07
EP3088006A1 (de) 2016-11-02
ES2720034T3 (es) 2019-07-17
SG11201708749WA (en) 2017-11-29
CA2983884A1 (en) 2016-11-03
RU2719363C2 (ru) 2020-04-17
HK1249867A1 (zh) 2018-11-16
MX2017013893A (es) 2018-03-15
IL255137A0 (en) 2017-12-31
WO2016173982A1 (de) 2016-11-03
US20190117803A1 (en) 2019-04-25
AR104440A1 (es) 2017-07-19
RU2017141168A (ru) 2019-05-28
CN107624073B (zh) 2020-05-22
SA517390240B1 (ar) 2021-03-01
JP6851981B2 (ja) 2021-03-31
ZA201708043B (en) 2020-01-29
CN107624073A (zh) 2018-01-23
BR112017023246B1 (pt) 2021-09-08
BR112017023246A2 (pt) 2020-05-19
IL255137B (en) 2020-10-29
JP2018517455A (ja) 2018-07-05
KR20170140219A (ko) 2017-12-20
AU2016254582B2 (en) 2020-01-30
RU2017141168A3 (enExample) 2019-11-14

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