MX377340B - Composiciones en solución sólida y uso en el tratamiento de enfermedades cardiovasculares. - Google Patents
Composiciones en solución sólida y uso en el tratamiento de enfermedades cardiovasculares.Info
- Publication number
- MX377340B MX377340B MX2015009104A MX2015009104A MX377340B MX 377340 B MX377340 B MX 377340B MX 2015009104 A MX2015009104 A MX 2015009104A MX 2015009104 A MX2015009104 A MX 2015009104A MX 377340 B MX377340 B MX 377340B
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- solid solution
- cardiovascular diseases
- solution compositions
- pharmaceutical compositions
- Prior art date
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
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Abstract
La presente especificación describe composiciones farmacéuticas, métodos de preparación de tales composiciones farmacéuticas y métodos y usos para el tratamiento de la inflamación crónica y/o de una enfermedad inflamatoria en un individuo que utilice tales composiciones farmacéuticas.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361752356P | 2013-01-14 | 2013-01-14 | |
| US201361752309P | 2013-02-04 | 2013-02-04 | |
| PCT/EP2014/050636 WO2014108572A1 (en) | 2013-01-14 | 2014-01-14 | Solid solution compositions and use in cardiovascular disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015009104A MX2015009104A (es) | 2016-07-26 |
| MX377340B true MX377340B (es) | 2025-03-06 |
Family
ID=50030251
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015009104A MX377340B (es) | 2013-01-14 | 2014-01-14 | Composiciones en solución sólida y uso en el tratamiento de enfermedades cardiovasculares. |
| MX2015009105A MX379193B (es) | 2013-01-14 | 2014-01-14 | Composiciones en solucion solida y su uso en inflamacion cronica. |
| MX2015009106A MX377877B (es) | 2013-01-14 | 2014-01-14 | Composiciones de solución sólida y su uso en el tratamiento del dolor intenso. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015009105A MX379193B (es) | 2013-01-14 | 2014-01-14 | Composiciones en solucion solida y su uso en inflamacion cronica. |
| MX2015009106A MX377877B (es) | 2013-01-14 | 2014-01-14 | Composiciones de solución sólida y su uso en el tratamiento del dolor intenso. |
Country Status (16)
| Country | Link |
|---|---|
| EP (6) | EP2943223B1 (es) |
| JP (6) | JP6378694B2 (es) |
| KR (6) | KR102252574B1 (es) |
| CN (4) | CN104981253B (es) |
| AU (4) | AU2014204735B2 (es) |
| BR (3) | BR112015015898B1 (es) |
| CA (3) | CA2898000A1 (es) |
| ES (5) | ES2829904T3 (es) |
| IL (5) | IL295091B2 (es) |
| MX (3) | MX377340B (es) |
| NZ (1) | NZ709486A (es) |
| PL (1) | PL3795141T3 (es) |
| RU (3) | RU2675241C2 (es) |
| SG (4) | SG11201505241WA (es) |
| WO (3) | WO2014108573A1 (es) |
| ZA (3) | ZA201505002B (es) |
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| US8895536B2 (en) | 2010-10-29 | 2014-11-25 | Infirst Healthcare Ltd. | Compositions and methods for treating chronic inflammation and inflammatory diseases |
| US11730709B2 (en) | 2010-10-29 | 2023-08-22 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
| US10695432B2 (en) | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
| US9308213B2 (en) | 2010-10-29 | 2016-04-12 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
| US11202831B2 (en) | 2010-10-29 | 2021-12-21 | Infirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
| US9744132B2 (en) | 2010-10-29 | 2017-08-29 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
| US10695431B2 (en) | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
| US11224659B2 (en) | 2010-10-29 | 2022-01-18 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
| US9271950B2 (en) | 2010-10-29 | 2016-03-01 | Infirst Healthcare Limited | Compositions for treating chronic inflammation and inflammatory diseases |
| US9504664B2 (en) | 2010-10-29 | 2016-11-29 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
| EP2943223B1 (en) * | 2013-01-14 | 2020-08-19 | InFirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
| PL3331568T3 (pl) * | 2015-08-07 | 2022-02-28 | Infirst Healthcare Limited | Kompozycje stałego roztworu dla nlpz |
| US10307388B2 (en) * | 2016-12-29 | 2019-06-04 | The United States Of America As Represented By The Secretary Of The Navy | Compositions and methods for diagnosis and treatment of inflammation |
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| JP7492459B2 (ja) * | 2018-05-16 | 2024-05-29 | エピトラッカー インコーポレイテッド | 加齢に関連する状態の診断及び治療のための組成物及び方法 |
| AU2019274431B2 (en) | 2018-05-23 | 2025-03-13 | Epitracker, Inc. | Compositions and methods for diagnosis and treatment of conditions related to the quality of aging and longevity |
| CN108653273A (zh) * | 2018-07-13 | 2018-10-16 | 昆明医科大学第附属医院 | 青蒿素类化合物作为制备治疗贝赫切特病药物的应用 |
| BR112021010847A2 (pt) | 2018-12-07 | 2021-09-08 | Neurocrine Biosciences Inc. | Antagonista de receptor de crf1, formulações farmacêuticas e formas sólidas das mesmas para o tratamento de hiperplasia adrenal congênita |
| WO2020146263A1 (en) | 2019-01-09 | 2020-07-16 | Epitracker, Inc. | Compositions and methods for diagnosis and treatment of neurodegenerative diseases |
| JP7404382B2 (ja) | 2019-03-04 | 2023-12-25 | エピトラッカー インコーポレイテッド | 脂肪酸アナログ、ならびに認知機能障害、行動症状および慢性疼痛の処置におけるそれらの使用 |
| CN110251549B (zh) * | 2019-06-24 | 2021-12-03 | 浙江省肿瘤医院 | 淫羊藿总黄酮提取物在制备防治桥本甲状腺炎的药物中的应用 |
| EP3991722A4 (en) * | 2019-06-28 | 2022-10-05 | Jiangsu Hengrui Medicine Co., Ltd. | LIPID COMPOSITION WITH DELAYED RELEASE AND THEIR PROCESS OF PRODUCTION |
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| AU2022248850A1 (en) | 2021-03-27 | 2023-11-09 | TRx Biosciences Limited | Compositions having improved bioavailability of therapeutics |
| US12370166B2 (en) | 2021-11-03 | 2025-07-29 | Epitracker, Inc. | Pentadecanoylcarnitine for treatment of conditions related to the quality of aging and longevity |
| CN114601843A (zh) * | 2022-03-22 | 2022-06-10 | 重庆医科大学附属第一医院 | 淫羊藿苷在制备治疗自身免疫性葡萄膜炎药物中的用途 |
| GB202208911D0 (en) * | 2022-06-17 | 2022-08-10 | Ravan Bio Limtied | Treatments |
| EP4568702A1 (en) | 2022-08-12 | 2025-06-18 | Jazz Pharmaceuticals Research UK Limited | Oral solid dosage forms comprising cannabinoids |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3800038A (en) * | 1972-04-21 | 1974-03-26 | Biolog Concepts Inc | Uterine administraton of eutectic solid solutions of steroid hormones in a steroidal lipid carrier |
| US5143934A (en) * | 1990-11-21 | 1992-09-01 | A/S Dumex (Dumex Ltd.) | Method and composition for controlled delivery of biologically active agents |
| GB9613858D0 (en) * | 1996-07-02 | 1996-09-04 | Cortecs Ltd | Hydrophobic preparations |
| SK284511B6 (sk) * | 1997-07-29 | 2005-05-05 | Pharmacia & Upjohn Company | Samoemulgujúce formulácie pre lipofilné zlúčeniny |
| US6063768A (en) | 1997-09-04 | 2000-05-16 | First; Eric R. | Application of botulinum toxin to the management of neurogenic inflammatory disorders |
| GB2331458B (en) * | 1997-11-21 | 2002-07-31 | Gursharan Singh Moonga | Solubilising systems for difficult pharmaceutical actives for preparing concentrated stable solutions for encapsulation into soft gelatine |
| US7374779B2 (en) * | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| AU4917900A (en) * | 1999-05-07 | 2000-11-21 | Pharmasol Gmbh | Lipid particles on the basis of mixtures of liquid and solid lipids and method for producing same |
| US8663692B1 (en) * | 1999-05-07 | 2014-03-04 | Pharmasol Gmbh | Lipid particles on the basis of mixtures of liquid and solid lipids and method for producing same |
| WO2000076478A1 (en) * | 1999-06-14 | 2000-12-21 | Cosmo S.P.A. | Controlled release and taste masking oral pharmaceutical compositions |
| DE60020382T2 (de) * | 1999-09-21 | 2006-01-26 | Skyepharma Canada Inc., Verdun | Oberflächenmodifizierte teilchenförmige zusammensetzungen biologisch aktiver stoffe |
| US6264981B1 (en) * | 1999-10-27 | 2001-07-24 | Anesta Corporation | Oral transmucosal drug dosage using solid solution |
| US20060034937A1 (en) * | 1999-11-23 | 2006-02-16 | Mahesh Patel | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| FR2805761B1 (fr) * | 2000-03-02 | 2002-08-30 | Mainelab | Nanocapsules lipidiques, procede de preparation et utilisation comme medicament |
| US6455067B1 (en) * | 2000-05-24 | 2002-09-24 | Sang-A Pharmaceutical Co., Ltd. | Transdermal patch for nonsteroidal antiinflammatory drug(s) |
| JP3763567B2 (ja) * | 2001-01-19 | 2006-04-05 | 株式会社資生堂 | 化粧料 |
| US20030105141A1 (en) * | 2001-04-17 | 2003-06-05 | Ping Gao | Finely self-emulsifiable pharmaceutical composition |
| CN1829510A (zh) * | 2003-07-31 | 2006-09-06 | 法马西亚和厄普乔恩公司 | 抗炎剂的可分散性制剂 |
| KR20060085686A (ko) * | 2003-10-10 | 2006-07-27 | 라이프사이클 파마 에이/에스 | 피브레이트를 포함하는 고형 제제 |
| SG148186A1 (en) * | 2003-11-13 | 2008-12-31 | Combinatorx Inc | Methods and reagents for the treatment of inflammatory disorders |
| DE04801160T1 (de) * | 2003-12-01 | 2007-08-09 | Lifecycle Pharma A/S | Pharmazeutische zusammensetzungen mit lercanidipin |
| EP1750717B1 (en) * | 2004-02-11 | 2017-07-19 | Rubicon Research Private Limited | Controlled release pharmaceutical compositions with improved bioavailability |
| DE602005009677D1 (de) * | 2004-03-22 | 2008-10-23 | Solvay Pharm Gmbh | Orale pharmazeutische zusammensetzungen von produkten mit lipase, insbesondere von pankreatin, mit tensiden |
| RU2007123366A (ru) * | 2004-11-24 | 2008-12-27 | Мерк Энд Ко. | Жидкие и полутвердые фармацевтические препаративные формы для перорального введения замещенного амида |
| US20060138059A1 (en) | 2004-12-28 | 2006-06-29 | Vair Larry L Jr | Corona-treated polypropylene liquid filtration media |
| EA012882B1 (ru) * | 2005-04-28 | 2009-12-30 | ДСМ АйПи ЭССЕТС Б.В. | Фармацевтические лекарственные формы, содержащие липидную фазу |
| GB0610867D0 (en) * | 2006-06-01 | 2006-07-12 | Syntaxin Ltd | Treatment of pain |
| GB0704846D0 (en) * | 2007-03-13 | 2007-04-18 | Futura Medical Dev Ltd | Topical pharmaceutical formulation |
| RU2353349C2 (ru) * | 2007-04-18 | 2009-04-27 | Общество с ограниченной ответственностью "Фармацевтические технологии" | Средство для лечения болезней суставов |
| CN101129335B (zh) * | 2007-07-17 | 2010-09-22 | 浙江大学 | 一种纳米结构脂质载体给药系统的用途 |
| EP2310371B1 (fr) | 2008-05-26 | 2013-05-15 | Genfit | Composés agonistes ppar, préparation et utilisations pour le traitement du diabète et/ou des dyslipidémies |
| GB201018289D0 (en) * | 2010-10-29 | 2010-12-15 | Biocopea Ltd | Treatment of respiratory disorders |
| CA2826506C (en) * | 2011-02-04 | 2017-07-25 | Biocopea Limited | Compositions and methods for treating chronic inflammation and inflammatory diseases |
| US20140079785A1 (en) * | 2011-03-24 | 2014-03-20 | Leo Pharma A/S | Composition comprising lipid nanoparticles and a corticosteroid or vitamin d derivative |
| CN102793628B (zh) * | 2012-08-23 | 2014-07-02 | 东华大学 | 用于化妆品的液-固混合脂质纳米缓释系统及其制备方法 |
| EP2943223B1 (en) * | 2013-01-14 | 2020-08-19 | InFirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
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