MX367430B - Parche no acuoso. - Google Patents

Parche no acuoso.

Info

Publication number
MX367430B
MX367430B MX2017015450A MX2017015450A MX367430B MX 367430 B MX367430 B MX 367430B MX 2017015450 A MX2017015450 A MX 2017015450A MX 2017015450 A MX2017015450 A MX 2017015450A MX 367430 B MX367430 B MX 367430B
Authority
MX
Mexico
Prior art keywords
lidocaine
solubilizing agent
patch
aqueous patch
adhesive force
Prior art date
Application number
MX2017015450A
Other languages
English (en)
Inventor
Saida Naoyuki
Mori Tatsuya
Original Assignee
Itochu Chemical Frontier Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Itochu Chemical Frontier Corp filed Critical Itochu Chemical Frontier Corp
Publication of MX367430B publication Critical patent/MX367430B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics

Abstract

Problema Si la lidocaína se incorpora al parche no acuoso, la fuerza adhesiva de la preparación tiende a disminuir, ya que la cantidad de composición de lidocaína es mayor. Es popular disolver la lidocaína en agente de disolución para incorporar la lidocaína en el parche y liberar una cantidad efectiva de lidocaína en la piel. Sin embargo, si la cantidad de agente de disolución aumenta, la fuerza adhesiva disminuye extremadamente, de modo que es difícil una unión de largo tiempo. Solución Un parche no acuoso que comprende lidocaína y/o su reactivo, y un agente de disolución que está contenido en una base de emplaste, el emplaste se mantiene por un respaldo, del cual la resistencia del 50% de estiramiento en dirección longitudinal es menor de 2,000g/50mm y de rela estirable biaxialmente orientada.
MX2017015450A 2011-09-27 2011-09-27 Parche no acuoso. MX367430B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2011/072072 WO2013046335A1 (ja) 2011-09-27 2011-09-27 非水性貼付剤

Publications (1)

Publication Number Publication Date
MX367430B true MX367430B (es) 2019-07-11

Family

ID=47994448

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2017015450A MX367430B (es) 2011-09-27 2011-09-27 Parche no acuoso.
MX2014003688A MX352752B (es) 2011-09-27 2011-09-27 Parche no acuoso.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2014003688A MX352752B (es) 2011-09-27 2011-09-27 Parche no acuoso.

Country Status (19)

Country Link
US (2) US10765640B2 (es)
EP (2) EP2823815B1 (es)
JP (1) JP6021269B2 (es)
BR (1) BR112014006719B1 (es)
CA (1) CA2850024C (es)
CY (1) CY1120754T1 (es)
DK (1) DK2823815T3 (es)
ES (2) ES2683006T3 (es)
HR (1) HRP20181230T1 (es)
HU (1) HUE039266T2 (es)
LT (1) LT2823815T (es)
MX (2) MX367430B (es)
PL (1) PL2823815T3 (es)
PT (1) PT2823815T (es)
RS (1) RS57451B1 (es)
SI (1) SI2823815T1 (es)
TR (1) TR201810942T4 (es)
TW (1) TW201318652A (es)
WO (1) WO2013046335A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9925264B2 (en) 2011-05-10 2018-03-27 Itochu Chemical Frontier Corporation Non-aqueous patch
EP2708229B1 (en) 2011-05-10 2019-07-31 Itochu Chemical Frontier Corporation Non-aqueous patch
US11786455B2 (en) 2011-05-10 2023-10-17 Itochu Chemical Frontier Corporation Non-aqueous patch
CA2850024C (en) 2011-09-27 2020-07-07 Itochu Chemical Frontier Corporation Non-aqueous patch comprising lidocaine
CN113893231A (zh) * 2015-08-24 2022-01-07 伊藤忠富隆达化工株式会社 包含利多卡因的非水性贴剂
JP6290521B1 (ja) * 2016-09-16 2018-03-07 ニチバン株式会社 貼付剤
TW201813635A (zh) 2016-09-16 2018-04-16 日商日絆股份有限公司 貼附劑
JPWO2020218249A1 (es) * 2019-04-24 2020-10-29
JP7179212B1 (ja) 2022-05-02 2022-11-28 久光製薬株式会社 リドカイン含有貼付剤
WO2023225143A1 (en) * 2022-05-19 2023-11-23 Tpc-Api Llc Highly elastic patches and masks for delivery of therapeutic agents

Family Cites Families (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE451669C (sv) 1984-02-17 1989-04-07 Moelnlycke Ab Kompress innehaallande zinkoxid
IL86170A (en) 1987-05-01 1992-12-01 Elan Transdermal Ltd Preparations and compositions comprising nicotine for percutaneous administration
US5656286A (en) 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5234957A (en) 1991-02-27 1993-08-10 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
DE69009540T2 (de) 1989-03-15 1994-09-29 Nitto Denko Corp Arzneimittel enthaltendes Heftpflaster.
CA1338779C (en) 1989-03-17 1996-12-10 Harry Hind Method for treating pain associated with herpes-zoster and post-herpetic neuralgia by topical application of local anesthetics
US5411738A (en) 1989-03-17 1995-05-02 Hind Health Care, Inc. Method for treating nerve injury pain associated with shingles (herpes-zoster and post-herpetic neuralgia) by topical application of lidocaine
US5098417A (en) 1990-04-12 1992-03-24 Ricoh Kyosan, Inc. Cellulosic wound dressing with an active agent ionically absorbed thereon
JP3115625B2 (ja) 1991-03-30 2000-12-11 帝國製薬株式会社 リドカイン含有外用貼付剤
EP0607434B1 (en) 1991-08-30 1999-01-27 Hisamitsu Pharmaceutical Co., Inc. Anti-inflammatory analgesic plaster
US5804213A (en) 1991-10-09 1998-09-08 Lectec Corporation Biologically active aqueous gel wound dressing
DE4224325C1 (de) 1992-07-23 1994-02-10 Sanol Arznei Schwarz Gmbh Wirkstoffpflaster für niedrigschmelzende und/oder flüchtige Wirkstoffe und Verfahren zu seiner Herstellung
US6056738A (en) 1997-01-31 2000-05-02 Transmedica International, Inc. Interstitial fluid monitoring
JPH07215850A (ja) 1994-02-04 1995-08-15 Sekisui Chem Co Ltd 局所麻酔用経皮吸収テープ
US5536263A (en) 1994-03-30 1996-07-16 Lectec Corporation Non-occulusive adhesive patch for applying medication to the skin
IL113034A (en) 1994-04-05 2000-02-17 Astra Ab Topical dressing
US5618274A (en) 1994-04-08 1997-04-08 Rosenthal; Kenneth J. Method and device for deep pressurized topical, fornix applied "nerve block" anesthesia
SE9401620L (sv) 1994-05-10 1996-01-10 Alpharma Ab Kombinerad användning av lokalbedövningsmedel och täckande förband
US5601839A (en) 1995-04-26 1997-02-11 Theratech, Inc. Triacetin as a penetration enhancer for transdermal delivery of a basic drug
US6245347B1 (en) 1995-07-28 2001-06-12 Zars, Inc. Methods and apparatus for improved administration of pharmaceutically active compounds
US6461644B1 (en) 1996-03-25 2002-10-08 Richard R. Jackson Anesthetizing plastics, drug delivery plastics, and related medical products, systems and methods
FR2748207B1 (fr) 1996-05-06 1998-06-12 Cird Galderma Composition a base d'un compose modulant la reactivite des fibres nerveuses
JPH09315964A (ja) 1996-05-27 1997-12-09 Chinhin Boku 肩こり・五十肩治療用貼付剤
CA2259418A1 (en) 1996-07-11 1998-01-22 Farmarc Nederland B.V. Pharmaceutical composition containing acid addition salt of basic drug
US5985317A (en) 1996-09-06 1999-11-16 Theratech, Inc. Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents
US6365178B1 (en) 1996-09-06 2002-04-02 Watson Pharmaceuticals, Inc. Method of making pressure sensitive adhesive matrix patches for transdermal drug delivery using hydrophilic salts of drugs and hydrophobic pressure sensitive adhesive dispersions
JPH10147521A (ja) 1996-09-18 1998-06-02 Yuutoku Yakuhin Kogyo Kk 持続性疼痛緩和用貼付剤
CN1232389A (zh) 1996-10-04 1999-10-20 崎玉第一制药株式会社 贴剂
JPH1149670A (ja) 1997-08-04 1999-02-23 Nichiban Co Ltd 局所麻酔用経皮吸収型製剤
US5891919A (en) 1997-09-19 1999-04-06 Burlington Bio-Medical & Scientific Corp. Denatonium capsaicinate and methods of producing the same
DE69833000T2 (de) 1997-09-26 2006-09-07 Noven Pharmaceuticals, Inc., Miami Bio-klebemittelzusammensetzungen
FR2770843B1 (fr) 1997-11-13 2000-01-14 Lavipharm Lab Association prolamines-lipides polaires vegetaux, son procede de preparation et ses applications
US6120792A (en) 1998-04-29 2000-09-19 Juni; Jack E. Medicated skin patch and method for its use
US6264927B1 (en) 1998-08-27 2001-07-24 Elmer P. Monahan Topical solution and method for the treatment of nail fungus
JP3159688B2 (ja) 1998-10-05 2001-04-23 祐徳薬品工業株式会社 経皮吸収テープ剤
US6953590B1 (en) 1998-10-05 2005-10-11 Yutoku Pharmaceutical Ind. Co., Ltd. Tape material for transcutaneous absorption
US7127285B2 (en) 1999-03-12 2006-10-24 Transport Pharmaceuticals Inc. Systems and methods for electrokinetic delivery of a substance
US6689380B1 (en) 1999-05-17 2004-02-10 Kevin S. Marchitto Remote and local controlled delivery of pharmaceutical compounds using electromagnetic energy
US6299902B1 (en) 1999-05-19 2001-10-09 The University Of Georgia Research Foundation, Inc. Enhanced transdermal anesthesia of local anesthetic agents
DE19923906A1 (de) 1999-05-26 2000-11-30 Basf Ag Optisch transparenter polymerer Festelektrolyt
US6580011B1 (en) 1999-07-29 2003-06-17 Barbara Jennings-Spring Circumcision/penile dressing
US6528086B2 (en) 1999-09-28 2003-03-04 Zars, Inc. Methods and apparatus for drug delivery involving phase changing formulations
US6383511B1 (en) 1999-10-25 2002-05-07 Epicept Corporation Local prevention or amelioration of pain from surgically closed wounds
US6264981B1 (en) 1999-10-27 2001-07-24 Anesta Corporation Oral transmucosal drug dosage using solid solution
AU4842100A (en) 1999-12-10 2001-06-18 Teri Buseman Anti pruritic patch
PT1238664E (pt) * 1999-12-15 2007-04-30 Hisamitsu Pharmaceutical Co Preparações de adesivo
US6455066B1 (en) 2000-03-10 2002-09-24 Epicept Corporation Intradermal-penetration agents for topical local anesthetic administration
JP2001302501A (ja) 2000-04-17 2001-10-31 Oishi Koseido:Kk 肩こり・膝関節痛・五十肩等の治療用貼付剤
KR20030060771A (ko) 2000-04-28 2003-07-16 메모리얼 슬로안-케터링 캔서 센터 국소용 마취제/아편양약물 제제 및 이들의 용도
WO2001095889A1 (fr) 2000-06-13 2001-12-20 Hisamitsu Pharmaceutical Co., Inc. Platre
GB0015617D0 (en) 2000-06-26 2000-08-16 Vectura Ltd Improved preparations for dermal delivery of active substances
JP4787397B2 (ja) * 2000-08-28 2011-10-05 日東電工株式会社 粘着剤組成物および粘着テープもしくはシート
US7288265B1 (en) 2000-10-16 2007-10-30 Lectec Corporation Treating viral infection at smallpox vaccination site
TWI287455B (en) * 2000-12-05 2007-10-01 Noven Pharma Crystallization inhibition of drugs in transdermal drug delivery systems and methods of use
US6830758B2 (en) 2001-04-02 2004-12-14 Lectec Corporation Psoriasis patch
US7094228B2 (en) 2001-07-31 2006-08-22 Zars, Inc. Methods and formulations for photodynamic therapy
US20030124174A1 (en) * 2001-10-25 2003-07-03 Endo Pharmaceuticals, Inc Method for treating non-neuropathic pain
JP2003137773A (ja) * 2001-10-31 2003-05-14 Hisamitsu Pharmaceut Co Inc 積層支持体を有する貼付剤
TWI312885B (en) 2001-12-06 2009-08-01 Nec Lcd Technologies Ltd Semi-transmissive liquid crystal display device
GB2382778B (en) 2001-12-07 2005-02-16 Blatchford & Sons Ltd An orthotic strut component
US7921999B1 (en) 2001-12-20 2011-04-12 Watson Laboratories, Inc. Peelable pouch for transdermal patch and method for packaging
JP2003191659A (ja) 2001-12-25 2003-07-09 Fuji Photo Film Co Ltd 平版印刷版用アルミニウム支持体とその製造方法、および平版印刷原版
JP4206342B2 (ja) 2002-02-19 2009-01-07 久光製薬株式会社 経皮吸収型貼付剤
JP4792193B2 (ja) * 2002-08-28 2011-10-12 久光製薬株式会社 貼付剤
US7166641B2 (en) 2002-10-02 2007-01-23 Yung Shin Pharmaceutical Industrial Co., Ltd. Pharmaceutically acceptable salts containing local anesthetic and anti-inflammatory activities and methods for preparing the same
US20040076671A1 (en) 2002-10-21 2004-04-22 Aletha Tippett Methods and compositions for topical wound treatment
US7993654B2 (en) 2002-12-23 2011-08-09 Beiersdorf Ag Self-adhesive polymer matrix containing sea algae extract
DE10260873A1 (de) 2002-12-23 2004-07-15 Beiersdorf Ag Selbstklebende Polymermatrix mit einem Gehalt an Meeresalgenextrakt und Glycerin
WO2004075943A1 (en) 2003-02-28 2004-09-10 Biointeractions Ltd. Polymeric network system for medical devices and methods of use
US7179477B2 (en) 2003-08-15 2007-02-20 Shyam K Gupta Cosmetic dermabrasion treatment system
US6998109B1 (en) 2004-01-07 2006-02-14 Pearson Research & Development Limited Emu-based formulations with lidocaine for wound treatment by inhibiting microbial activity
ES2372959T3 (es) 2004-01-29 2012-01-30 Medrx Co., Ltd. Analgésico anti-inflamatorio para uso externo.
US8741332B2 (en) * 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for dermally treating neuropathic pain
WO2006017632A1 (en) * 2004-08-04 2006-02-16 Cassel Douglas R An analgesic patch for sports injury and rehabilitation medicine and method to alleviate pain
MX2007004315A (es) 2004-10-08 2008-03-11 Noven Pharma Dispositivo para suministro transdermico de farmaco que incluye un respaldo oclusivo.
WO2007070679A2 (en) 2005-12-14 2007-06-21 Zars, Inc. Compositions and methods for dermally treating pain
JP5037831B2 (ja) * 2006-02-15 2012-10-03 久光製薬株式会社 凝集力向上及び徐放化の外用貼付剤
US7695733B2 (en) 2006-02-17 2010-04-13 Zasler Nathan D Application of topical anesthetics for modulation of neurogenic tremor
US7910135B2 (en) 2006-10-13 2011-03-22 Uluru Inc. Hydrogel wound dressing and biomaterials formed in situ and their uses
US20100003313A1 (en) 2006-10-27 2010-01-07 Hisamitsu Pharmaceutical Co.,Inc. Adhesive skin patch
US7904146B2 (en) 2006-11-13 2011-03-08 Travanti Pharma Inc. Transdermal systems for the delivery of ionic agents directly to open wounds and surgically repaired incisions
EP2093594B1 (en) * 2006-12-01 2013-01-09 Kuraray Co., Ltd. Pressure-sensitive adhesive for optical films
WO2008093686A1 (ja) 2007-01-29 2008-08-07 Medrx Co., Ltd. 非ステロイド系抗炎症薬と有機アミン化合物との塩とその用途
CN101861148B (zh) 2007-11-11 2013-04-03 美德阿利克斯株式会社 利多卡因胶带制剂
JP5130026B2 (ja) * 2007-11-16 2013-01-30 日東電工株式会社 貼付剤および貼付製剤
WO2009133610A1 (ja) * 2008-04-30 2009-11-05 株式会社 総健美 疼痛処置用皮膚貼付具
US20090297591A1 (en) 2008-05-30 2009-12-03 Orient Pharma Co., Ltd. Compositions And Methods For The Transdermal Delivery Of Pharmaceutical Compounds
US8231906B2 (en) 2008-07-10 2012-07-31 Noven Pharmaceuticals, Inc. Transdermal estrogen device and delivery
JP5544544B2 (ja) 2008-08-05 2014-07-09 株式会社 メドレックス 塩基性薬効成分の脂肪酸塩、安息香酸塩を含有する外用剤とその製造方法
US20100092544A1 (en) 2008-10-14 2010-04-15 Katsuhiro Okada Adhesive composition for patch and use thereof
US8815261B2 (en) 2009-06-19 2014-08-26 Medrx Co., Ltd. Composition for external application comprising aripiprazole and organic acid as active ingredients
AU2010274374B2 (en) 2009-07-24 2014-08-14 Teikoku Seiyaku Co., Ltd. Fentanyl-containing adhesive preparation for external use
KR101070864B1 (ko) 2009-12-11 2011-10-10 김성한 광학식 터치스크린
TWI482645B (zh) 2010-01-07 2015-05-01 Teikoku Seiyaku Kk 含有待克菲那(diclofenac)羥乙基吡咯啶之外用油性敷貼劑
US9925264B2 (en) 2011-05-10 2018-03-27 Itochu Chemical Frontier Corporation Non-aqueous patch
EP2708229B1 (en) 2011-05-10 2019-07-31 Itochu Chemical Frontier Corporation Non-aqueous patch
US11786455B2 (en) 2011-05-10 2023-10-17 Itochu Chemical Frontier Corporation Non-aqueous patch
CA2850024C (en) 2011-09-27 2020-07-07 Itochu Chemical Frontier Corporation Non-aqueous patch comprising lidocaine
CN113893231A (zh) 2015-08-24 2022-01-07 伊藤忠富隆达化工株式会社 包含利多卡因的非水性贴剂
WO2019220420A1 (en) 2018-05-18 2019-11-21 Pedranti William Non-aqueous patch with superior adhesion characteristics

Also Published As

Publication number Publication date
PL2823815T3 (pl) 2018-10-31
SI2823815T1 (sl) 2018-09-28
CA2850024A1 (en) 2013-04-04
CA2850024C (en) 2020-07-07
HUE039266T2 (hu) 2018-12-28
TR201810942T4 (tr) 2018-09-21
JPWO2013046335A1 (ja) 2015-03-26
EP2823815B1 (en) 2018-07-04
EP2823815A1 (en) 2015-01-14
BR112014006719A2 (pt) 2017-06-13
PT2823815T (pt) 2018-10-22
EP3363432A1 (en) 2018-08-22
JP6021269B2 (ja) 2016-11-09
ES2845524T3 (es) 2021-07-27
ES2683006T3 (es) 2018-09-24
MX2014003688A (es) 2014-07-28
EP3363432B1 (en) 2020-12-23
EP2823815A4 (en) 2015-10-14
TW201318652A (zh) 2013-05-16
US10765640B2 (en) 2020-09-08
DK2823815T3 (en) 2018-08-06
US20140356412A1 (en) 2014-12-04
WO2013046335A1 (ja) 2013-04-04
RS57451B1 (sr) 2018-09-28
US11793766B2 (en) 2023-10-24
US20210038531A1 (en) 2021-02-11
BR112014006719B1 (pt) 2021-09-14
HRP20181230T1 (hr) 2018-10-05
MX352752B (es) 2017-12-06
LT2823815T (lt) 2018-08-27
CY1120754T1 (el) 2019-12-11

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