MX365931B - Derivados de acidos carboxilicos con un anillo de oxazolo[5,4-b]piridina. - Google Patents

Derivados de acidos carboxilicos con un anillo de oxazolo[5,4-b]piridina.

Info

Publication number
MX365931B
MX365931B MX2014000024A MX2014000024A MX365931B MX 365931 B MX365931 B MX 365931B MX 2014000024 A MX2014000024 A MX 2014000024A MX 2014000024 A MX2014000024 A MX 2014000024A MX 365931 B MX365931 B MX 365931B
Authority
MX
Mexico
Prior art keywords
oxazolo
carboxylic acid
acid derivatives
pyridine ring
compounds
Prior art date
Application number
MX2014000024A
Other languages
English (en)
Other versions
MX2014000024A (es
Inventor
Schäfer Matthias
Kadereit Dieter
Huebschle Thomas
Hiss Katrin
Hachtel Stephanie
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of MX2014000024A publication Critical patent/MX2014000024A/es
Publication of MX365931B publication Critical patent/MX365931B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La invención se refiere por lo tanto a compuestos de la fórmula I (ver Fórmula) en donde X, Y, R1, R2 y R3 tienen los significados indicados. Los compuestos de la fórmula I son adecuados; por ejemplo, para la curación de heridas.
MX2014000024A 2011-07-07 2012-07-06 Derivados de acidos carboxilicos con un anillo de oxazolo[5,4-b]piridina. MX365931B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11305877 2011-07-07
EP12305525 2012-05-11
PCT/EP2012/063297 WO2013004826A1 (de) 2011-07-07 2012-07-06 Carbonsäurederivate mit einem oxazolo[5,4-b]pyridinring

Publications (2)

Publication Number Publication Date
MX2014000024A MX2014000024A (es) 2014-02-27
MX365931B true MX365931B (es) 2019-06-20

Family

ID=46466551

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014000024A MX365931B (es) 2011-07-07 2012-07-06 Derivados de acidos carboxilicos con un anillo de oxazolo[5,4-b]piridina.

Country Status (21)

Country Link
US (1) US8580816B2 (es)
EP (1) EP2729473B1 (es)
JP (1) JP5984925B2 (es)
KR (1) KR20140061384A (es)
CN (1) CN103781790B (es)
AU (1) AU2012280206B2 (es)
BR (1) BR112014000100A2 (es)
CA (1) CA2841220C (es)
CY (1) CY1117390T1 (es)
DK (1) DK2729473T3 (es)
ES (1) ES2562852T3 (es)
HK (1) HK1192239A1 (es)
HR (1) HRP20160167T1 (es)
HU (1) HUE026432T2 (es)
MX (1) MX365931B (es)
MY (1) MY164133A (es)
PL (1) PL2729473T3 (es)
PT (1) PT2729473E (es)
RU (1) RU2609002C2 (es)
SI (1) SI2729473T1 (es)
WO (1) WO2013004826A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9321787B2 (en) 2011-07-07 2016-04-26 Sanofi Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring
US8907093B2 (en) * 2011-07-07 2014-12-09 Sanofi Carboxylic acid derivatives having an oxazolo[4,5-c]pyridine ring

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO143535C (no) * 1972-06-14 1981-03-04 Merck & Co Inc Analogifremgangsmaate ved fremstilling av terapeutisk aktive oxazolopyridiner
ES2259707T3 (es) * 2001-05-14 2006-10-16 Novartis Ag Oxazolo y furopirimidinas y su uso en medicamentos contra tumores.
US7060697B2 (en) * 2003-05-19 2006-06-13 Irm Llc Immunosuppressant compounds and compositions
WO2007061458A2 (en) * 2005-11-23 2007-05-31 Epix Delaware, Inc. S1p receptor modulating compounds and use thereof
EP1900729A1 (en) * 2006-09-15 2008-03-19 Novartis AG Benzoxazoles and oxazolopyridines being useful as Janus kinases inhibitors
EP2121648A2 (en) 2007-03-21 2009-11-25 EPIX Pharmaceuticals, Inc. S1p receptor modulating compounds and use thereof
US8530483B2 (en) 2008-05-30 2013-09-10 Merck Sharp & Dohme Corp. Substituted azabenzoxazoles
TW201000099A (en) * 2008-06-20 2010-01-01 Amgen Inc S1P1 receptor agonists and use thereof
NZ590377A (en) 2008-07-15 2011-11-25 Sanofi Aventis Oxazolopyrimidines as edg-1 receptor agonists
US8907093B2 (en) * 2011-07-07 2014-12-09 Sanofi Carboxylic acid derivatives having an oxazolo[4,5-c]pyridine ring

Also Published As

Publication number Publication date
HUE026432T2 (en) 2016-05-30
AU2012280206A1 (en) 2014-01-23
EP2729473A1 (de) 2014-05-14
KR20140061384A (ko) 2014-05-21
AU2012280206B2 (en) 2016-07-28
DK2729473T3 (en) 2016-02-29
CA2841220A1 (en) 2013-01-10
HRP20160167T1 (hr) 2016-03-11
RU2014104232A (ru) 2015-08-20
RU2609002C2 (ru) 2017-01-30
MY164133A (en) 2017-11-30
JP5984925B2 (ja) 2016-09-06
CA2841220C (en) 2019-07-30
US20130023557A1 (en) 2013-01-24
CN103781790A (zh) 2014-05-07
HK1192239A1 (zh) 2014-08-15
CY1117390T1 (el) 2017-04-26
EP2729473B1 (de) 2015-11-25
WO2013004826A1 (de) 2013-01-10
JP2014518247A (ja) 2014-07-28
SI2729473T1 (sl) 2016-03-31
US8580816B2 (en) 2013-11-12
CN103781790B (zh) 2016-04-27
PT2729473E (pt) 2016-03-22
ES2562852T3 (es) 2016-03-08
MX2014000024A (es) 2014-02-27
PL2729473T3 (pl) 2016-05-31
BR112014000100A2 (pt) 2017-01-10

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