MX363017B - Métodos y productos para la expresión de proteínas en células. - Google Patents

Métodos y productos para la expresión de proteínas en células.

Info

Publication number
MX363017B
MX363017B MX2015005346A MX2015005346A MX363017B MX 363017 B MX363017 B MX 363017B MX 2015005346 A MX2015005346 A MX 2015005346A MX 2015005346 A MX2015005346 A MX 2015005346A MX 363017 B MX363017 B MX 363017B
Authority
MX
Mexico
Prior art keywords
methods
cells
products
proteins
nucleic acids
Prior art date
Application number
MX2015005346A
Other languages
English (en)
Spanish (es)
Other versions
MX2015005346A (es
Inventor
Angel Matthew
Rohde Christopher
Original Assignee
Factor Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Factor Bioscience Inc filed Critical Factor Bioscience Inc
Publication of MX2015005346A publication Critical patent/MX2015005346A/es
Publication of MX363017B publication Critical patent/MX363017B/es

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    • C—CHEMISTRY; METALLURGY
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
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    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
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    • C12N9/14—Hydrolases (3)
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    • C12Y—ENZYMES
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    • C12Y301/21—Endodeoxyribonucleases producing 5'-phosphomonoesters (3.1.21)
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
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MX2015005346A 2012-11-01 2013-11-01 Métodos y productos para la expresión de proteínas en células. MX363017B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261721302P 2012-11-01 2012-11-01
US201361785404P 2013-03-14 2013-03-14
US201361842874P 2013-07-03 2013-07-03
PCT/US2013/068118 WO2014071219A1 (en) 2012-11-01 2013-11-01 Methods and products for expressing proteins in cells

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MX2015005346A MX2015005346A (es) 2015-07-14
MX363017B true MX363017B (es) 2019-03-04

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MX2015005346A MX363017B (es) 2012-11-01 2013-11-01 Métodos y productos para la expresión de proteínas en células.
MX2019002498A MX2019002498A (es) 2012-11-01 2015-04-27 Metodos y productos para la expresion de proteinas en celulas.

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US (19) US9447395B2 (enExample)
EP (2) EP2914728B1 (enExample)
JP (5) JP6510416B2 (enExample)
KR (4) KR102121086B1 (enExample)
CN (1) CN104769112A (enExample)
AU (3) AU2013337651B2 (enExample)
BR (2) BR122019025681B1 (enExample)
CA (2) CA2890110C (enExample)
MX (2) MX363017B (enExample)
RU (2) RU2711249C2 (enExample)
WO (1) WO2014071219A1 (enExample)

Families Citing this family (126)

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Publication number Priority date Publication date Assignee Title
DE10347710B4 (de) 2003-10-14 2006-03-30 Johannes-Gutenberg-Universität Mainz Rekombinante Impfstoffe und deren Verwendung
DE102005046490A1 (de) 2005-09-28 2007-03-29 Johannes-Gutenberg-Universität Mainz Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
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