AU2013337651B2 - Methods and products for expressing proteins in cells - Google Patents

Methods and products for expressing proteins in cells Download PDF

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Publication number
AU2013337651B2
AU2013337651B2 AU2013337651A AU2013337651A AU2013337651B2 AU 2013337651 B2 AU2013337651 B2 AU 2013337651B2 AU 2013337651 A AU2013337651 A AU 2013337651A AU 2013337651 A AU2013337651 A AU 2013337651A AU 2013337651 B2 AU2013337651 B2 AU 2013337651B2
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gene
composition
protein
cell
seq
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AU2013337651A1 (en
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Matthew Angel
Christopher Rohde
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Factor Bioscience Inc
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Factor Bioscience Inc
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    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • A61K31/7115Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
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    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
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    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102Mutagenizing nucleic acids
    • C12N15/1024In vivo mutagenesis using high mutation rate "mutator" host strains by inserting genetic material, e.g. encoding an error prone polymerase, disrupting a gene for mismatch repair
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    • C12N15/90Stable introduction of foreign DNA into chromosome
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
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AU2013337651A 2012-11-01 2013-11-01 Methods and products for expressing proteins in cells Active AU2013337651B2 (en)

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AU2018264115A AU2018264115B2 (en) 2012-11-01 2018-11-16 Methods and products for expressing proteins in cells
AU2021250972A AU2021250972A1 (en) 2012-11-01 2021-10-15 Methods and products for expressing proteins in cells

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US201261721302P 2012-11-01 2012-11-01
US61/721,302 2012-11-01
US201361785404P 2013-03-14 2013-03-14
US61/785,404 2013-03-14
US201361842874P 2013-07-03 2013-07-03
US61/842,874 2013-07-03
PCT/US2013/068118 WO2014071219A1 (en) 2012-11-01 2013-11-01 Methods and products for expressing proteins in cells

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AU2013337651B2 true AU2013337651B2 (en) 2018-12-13

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US (19) US9447395B2 (enExample)
EP (2) EP3786298A1 (enExample)
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BR (2) BR122019025681B1 (enExample)
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