MX358134B - Antagonistas del receptor st2l y metodos de uso. - Google Patents
Antagonistas del receptor st2l y metodos de uso.Info
- Publication number
- MX358134B MX358134B MX2014013200A MX2014013200A MX358134B MX 358134 B MX358134 B MX 358134B MX 2014013200 A MX2014013200 A MX 2014013200A MX 2014013200 A MX2014013200 A MX 2014013200A MX 358134 B MX358134 B MX 358134B
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- antagonists
- st2l
- st2l antagonists
- fragments
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
- Y10S530/809—Fused cells, e.g. hybridoma
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Catching Or Destruction (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261640407P | 2012-04-30 | 2012-04-30 | |
| US201261640238P | 2012-04-30 | 2012-04-30 | |
| US13/798,226 US9212227B2 (en) | 2012-04-30 | 2013-03-13 | ST2L antibody antagonists for the treatment of ST2L-mediated inflammatory pulmonary conditions |
| US13/798,204 US9090694B2 (en) | 2012-04-30 | 2013-03-13 | ST2L antibody antagonists |
| PCT/US2013/038637 WO2013165894A2 (en) | 2012-04-30 | 2013-04-29 | St2l antagonists and methods of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014013200A MX2014013200A (es) | 2014-12-08 |
| MX358134B true MX358134B (es) | 2018-08-06 |
Family
ID=49477497
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014013200A MX358134B (es) | 2012-04-30 | 2013-04-29 | Antagonistas del receptor st2l y metodos de uso. |
| MX2018009430A MX2018009430A (es) | 2012-04-30 | 2014-10-30 | Antagonistas del receptor st2l y metodos de uso. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018009430A MX2018009430A (es) | 2012-04-30 | 2014-10-30 | Antagonistas del receptor st2l y metodos de uso. |
Country Status (37)
Families Citing this family (43)
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| CN102711810B (zh) | 2009-11-30 | 2015-04-22 | č©¹ę£®ēē©ē§ęå ¬åø | ęåŗååč½å·²ę¶é¤ēęä½FcåŗēŖåä½ |
| US10053513B2 (en) | 2009-11-30 | 2018-08-21 | Janssen Biotech, Inc. | Antibody Fc mutants with ablated effector functions |
| US9212227B2 (en) * | 2012-04-30 | 2015-12-15 | Janssen Biotech, Inc. | ST2L antibody antagonists for the treatment of ST2L-mediated inflammatory pulmonary conditions |
| AR091069A1 (es) * | 2012-05-18 | 2014-12-30 | Amgen Inc | Proteinas de union a antigeno dirigidas contra el receptor st2 |
| JO3532B1 (ar) | 2013-03-13 | 2020-07-05 | Regeneron Pharma | Ų§ŁŲ£Ų¬Ų³Ų§Ł Ų§ŁŁ Ų¶Ų§ŲÆŲ© ŁŁ Ų¶Ų§ŲÆ Ų§ŁŲŖŲ±ŁŁŁŁŁ-33 ŁŲ§Ų³ŲŖŲ¹Ł Ų§ŁŲ§ŲŖŁŲ§ |
| JP6404314B2 (ja) | 2013-03-15 | 2018-10-10 | ćŖćøć§ććć³ć»ćć”ć¼ćć·ć„ć¼ćć£ć«ć«ćŗć»ć¤ć³ć³ć¼ćć¬ć¤ćććļ¼²ļ½ ļ½ļ½ ļ½ļ½ ļ½ļ½ļ½ ļ¼°ļ½ļ½ļ½ļ½ļ½ļ½ļ½ ļ½ļ½ļ½ļ½ļ½ļ½ļ½ļ¼ ļ¼©ļ½ļ½ļ¼ | ļ¼©ļ½āļ¼ļ¼ę®ęč¬ćØćć®ä½æēØę³ |
| SG11201605580RA (en) | 2014-01-10 | 2016-10-28 | Anaptysbio Inc | Antibodies directed against interleukin-33 (il-33) |
| CA2946511C (en) | 2014-04-21 | 2023-08-22 | The Childen's Hospital Of Philadelphia | Compositions and methods for treating cytokine-related disorders |
| US9631024B2 (en) | 2014-06-23 | 2017-04-25 | Bionomics, Inc. | Antibodies that bind LGR4, their use in inhibiting neoplastic cells and in treating tumors |
| US11708608B2 (en) | 2014-11-10 | 2023-07-25 | Genentech, Inc. | Therapeutic and diagnostic methods for IL-33-mediated disorders |
| JP6929771B2 (ja) | 2014-11-10 | 2021-09-01 | ćøć§ćć³ćććÆļ¼ ć¤ć³ć³ć¼ćć¬ć¤ććć | ęć¤ć³ćæć¼ćć¤ćć³āļ¼ļ¼ęä½åć³ćć®ä½æēØ |
| WO2016140921A1 (en) * | 2015-03-02 | 2016-09-09 | 180 Therapeutics Lp | Method of treating a localized fibrotic disorder using an il-33 antagonist |
| CN108026172B (zh) | 2015-06-26 | 2022-04-29 | čµčÆŗč²ēē©ęęÆå ¬åø | åå éęil-1racpęä½ |
| AU2017208099A1 (en) * | 2016-01-14 | 2018-08-09 | Anaptysbio, Inc. | Inhibition of allergic reaction using an IL-33 inhibitor |
| EP3241845A1 (en) | 2016-05-06 | 2017-11-08 | MAB Discovery GmbH | Humanized anti-il-1r3 antibodies |
| US20190225682A1 (en) * | 2016-09-02 | 2019-07-25 | 180 Therapeutics Lp | Method of treating localized fibrotic disorders using an il-33/tnf bispecific antibody |
| WO2018045213A1 (en) * | 2016-09-02 | 2018-03-08 | 180 Therapeutics Lp | Method of treating systemic fibrotic disorders using an il-33/tnf bispecific antibody |
| JOP20190093A1 (ar) | 2016-10-28 | 2019-04-25 | Lilly Co Eli | Ų£Ų¬Ų³Ų§Ł Ł Ų¶Ų§ŲÆŲ© ŁŁ il-33 ŁŲ§Ų³ŲŖŲ®ŲÆŲ§Ł Ų§ŲŖŁŲ§ |
| TWI784988B (zh) | 2016-12-01 | 2022-12-01 | ē¾ååēå é«č„å ¬åø | ę²»ēē¼ēēēēę¹ę³ |
| CN116715775A (zh) | 2017-02-10 | 2023-09-08 | č±Ŗ夫čæĀ·ē½ę°ęéå ¬åø | ęē±»č°čē½é ¶ęä½ćå ¶ē»åē©åå ¶ēØé |
| WO2018178076A1 (en) * | 2017-03-29 | 2018-10-04 | F. Hoffmann-La Roche Ag | Bispecific antigen binding molecule for a costimulatory tnf receptor |
| MX2019012171A (es) | 2017-04-13 | 2019-11-25 | Regeneron Pharma | Tratamiento e inhibicion de enfermedades pulmonares inflamatorias en pacientes que tienen alelos de riesgo en los genes que codifican la il33 e il1rl1. |
| EP3401332A1 (en) | 2017-05-08 | 2018-11-14 | MAB Discovery GmbH | Anti-il-1r3 antibodies for use in inflammatory conditions |
| PE20201149A1 (es) | 2017-12-21 | 2020-10-26 | Hoffmann La Roche | Anticuerpos de union a hla-a2/wt1 |
| KR20220098056A (ko) | 2018-02-09 | 2022-07-08 | ģ ėØķ ķ¬, ģøķ¬. | ė¹ė§ ģøķ¬ ė§¤ź° ģ¼ģ¦ģ± ģ§ķģ ėķ ģ¹ė£ ė° ģ§ėØ ė°©ė² |
| IL307286B2 (en) | 2018-04-11 | 2026-03-01 | Regeneron Pharma | Methods and compositions for quantifying il-33 |
| SG11202104120VA (en) * | 2018-10-31 | 2021-05-28 | Delinia Inc | Multivalent regulatory t cell modulators |
| KR102353568B1 (ko) * | 2018-11-14 | 2022-01-20 | ģ£¼ģķģ¬ ķ¬ė¦ģ¤ėÆøģ¤ | ģģ ģ±ģ“ ķ„ģė ķ c-Met ķģ²“ ėė ź·øģ ķģ ź²°ķ© ėØķø |
| CN110045131B (zh) * | 2019-06-14 | 2019-09-03 | čæåØ(äøęµ·)ēē©ē§ęęéå ¬åø | ēØäŗęµå®äŗŗil-33/st2éč·Æęå¶åēēē©å¦ę“»ę§ēę¹ę³ |
| JP7843701B2 (ja) | 2019-11-04 | 2026-04-10 | ć”ćć£ćć„ć¼ć³ ćŖćććć | ļ¼©ļ½ļ¼ļ¼ļ¼ć¢ć³ćæć“ćć¹ćć®ä½æēØę¹ę³ |
| KR20220092927A (ko) | 2019-11-04 | 2022-07-04 | ė©ėė®Ø ė¦¬ėÆøķ°ė | ģ ģ„ ģ„ģ ė„¼ ģ¹ė£ķźø° ģķ ķ il-33 ģ¹ė£ģ |
| EP4118114A1 (en) | 2020-03-13 | 2023-01-18 | Genentech, Inc. | Anti-interleukin-33 antibodies and uses thereof |
| JP2023516497A (ja) | 2020-03-13 | 2023-04-19 | ć”ćć¤ćć„ć¼ć³ć»ćŖćććć | ļ¼©ļ½ļ¼ļ¼ć«ćŖć¹ćÆć¢ć¬ć«ćęććåÆ¾č±”ćę²»ēććććć®ę²»ēę¹ę³ |
| CN115867575A (zh) | 2020-04-06 | 2023-03-28 | å ē«å»ēęéå ¬åø | ēØil-33č½“ē»åę®ęåę²»ēę„ę§å¼åøēŖčæ«ē»¼åå¾ |
| CN121914272A (zh) * | 2020-05-12 | 2026-04-24 | ę£å¤§å¤©ę“čÆäøéå¢č”份ęéå ¬åø | St2ęåē»åčē½ |
| CN113501878B (zh) * | 2021-02-03 | 2022-12-02 | åäŗ¬ęŗä»ē¾åēē©ē§ęęéå ¬åø | éåƹäŗŗtslpēå¤ē§ęä½åå ¶ēØé |
| CA3217279A1 (en) | 2021-05-04 | 2022-11-10 | Olga Ignatovich | Anti-tigit antibodies and methods of use thereof |
| AR125753A1 (es) | 2021-05-04 | 2023-08-09 | Agenus Inc | Anticuerpos anti-tigit, anticuerpos anti-cd96 y mƩtodos de uso de estos |
| WO2023086807A1 (en) | 2021-11-10 | 2023-05-19 | Genentech, Inc. | Anti-interleukin-33 antibodies and uses thereof |
| CN119183384A (zh) * | 2022-02-24 | 2024-12-24 | äøå½ęä½å¶čÆęéå ¬åø | éåƹč¦ę„ē“ ēåē¹å¼ę§ē»åčē½åå ¶ēØé |
| CN115838425B (zh) * | 2022-08-31 | 2024-06-18 | é¦é½å»ē§å¤§å¦ | äøē§é¶åč”ē®”ē“§å¼ ē“ ii 1ååä½ē»čå¤ē¬¬äŗēÆēęä½åå ¶åŗēØ |
| US12054552B2 (en) | 2022-09-21 | 2024-08-06 | Sanofi Biotechnology | Humanized anti-IL-1R3 antibody and methods of use |
| CN119841936B (zh) * | 2024-12-30 | 2025-09-30 | äøå½åäøē§å¦é¢å °å·å ½å»ē ē©¶ę(äøå½åØē©å«ēäøęµč”ē å¦äøåæå °å·åäøåæ) | ęéę“²ēŖēē ęÆp72čē½äøåę§åå éęä½5d2åå ¶åŗēØ |
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