MX355996B - Isoxazolinas como agentes terapeuticos. - Google Patents

Isoxazolinas como agentes terapeuticos.

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Publication number
MX355996B
MX355996B MX2013012686A MX2013012686A MX355996B MX 355996 B MX355996 B MX 355996B MX 2013012686 A MX2013012686 A MX 2013012686A MX 2013012686 A MX2013012686 A MX 2013012686A MX 355996 B MX355996 B MX 355996B
Authority
MX
Mexico
Prior art keywords
aromatic
isoxazolines
therapeutic agents
solvates
stereoisomers
Prior art date
Application number
MX2013012686A
Other languages
English (en)
Other versions
MX2013012686A (es
Inventor
C Breinlinger Eric
J Calderwood David
L Swann Steven
Mukherjee Subhendu
Srikanth Chitty Venkata
Sanjeeva Rao Thunuguntla Siva
Seetharama Shastry Hosahalli Subramanya
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47108012&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX355996(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of MX2013012686A publication Critical patent/MX2013012686A/es
Publication of MX355996B publication Critical patent/MX355996B/es

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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Abstract

La presente invención proporciona un compuesto de la Fórmula (I), metabolitos biológicamente activos, profármacos, isómeros, estereoisómeros, solvatos, hidratos y sales farmacéuticamente aceptables del mismo, donde las variables se han definido en la presente. Los compuestos de la invención son útiles para tratar condiciones inmunológicas. X es un sistema de anillo opcionalmente sustituido, el cual es aromático, parcialmente aromático o no aromático teniendo uno o más sistemas de anillos fusionados.
MX2013012686A 2011-04-30 2012-04-30 Isoxazolinas como agentes terapeuticos. MX355996B (es)

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PCT/US2012/035832 WO2012151158A1 (en) 2011-04-30 2012-04-30 Isoxazolines as therapeutic agents

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MY163870A (en) 2017-10-31
IL229081A0 (en) 2013-12-31
JP6101250B2 (ja) 2017-03-22
DOP2013000251A (es) 2014-02-28
US9029409B2 (en) 2015-05-12
TW201247657A (en) 2012-12-01
JP2014513122A (ja) 2014-05-29
CA2834237A1 (en) 2012-11-08
US20150297596A1 (en) 2015-10-22
PH12016500838A1 (en) 2016-09-26
UY34043A (es) 2012-10-31
MX2013012686A (es) 2013-12-02
EP2704712A4 (en) 2014-10-15
US20130023526A1 (en) 2013-01-24
WO2012151158A1 (en) 2012-11-08
AU2012250979A1 (en) 2013-04-18
SG194696A1 (en) 2013-12-30
CR20130597A (es) 2014-02-24
CL2013003125A1 (es) 2014-04-25
AU2012250979B2 (en) 2015-07-30
ECSP13013026A (es) 2014-01-31
CN103764145A (zh) 2014-04-30
PH12013502218A1 (en) 2019-06-03
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