MX354089B - Metodos y aparato para la deteccion de sensibilidad al gluten y su diferenciacion de la enfermedad celiaca. - Google Patents

Metodos y aparato para la deteccion de sensibilidad al gluten y su diferenciacion de la enfermedad celiaca.

Info

Publication number
MX354089B
MX354089B MX2013008471A MX2013008471A MX354089B MX 354089 B MX354089 B MX 354089B MX 2013008471 A MX2013008471 A MX 2013008471A MX 2013008471 A MX2013008471 A MX 2013008471A MX 354089 B MX354089 B MX 354089B
Authority
MX
Mexico
Prior art keywords
gliadin
mer
transglutaminase
glutenin
antigen
Prior art date
Application number
MX2013008471A
Other languages
English (en)
Other versions
MX2013008471A (es
Inventor
Aristo Vojdani
Original Assignee
Cyrex Laboratories Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cyrex Laboratories Llc filed Critical Cyrex Laboratories Llc
Publication of MX2013008471A publication Critical patent/MX2013008471A/es
Publication of MX354089B publication Critical patent/MX354089B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/24—Immunology or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La presente invención se refiere a un método in vitro de caracterización de una composición de anticuerpo de una muestra de un animal caracterizado porque comprende: medir una primera señal derivada de una unión de un primer anticuerpo de la muestra a un antígeno de trigo entero que se puede obtener al combinar proteínas solubles en agua y proteínas solubles en alcohol extraídas del trigo; medir una segunda señal derivada de una unión de un segundo anticuerpo de la muestra a un antígeno de gliadina; y medir una tercera señal derivada de una unión de un tercer anticuerpo de la muestra a un antígeno seleccionado del grupo que consiste de: (1) una aglutinina de germen de trigo; (2) glutaomorfina; (3) una glutenia; (4) una glutenina desamidada; (5) una prodinorfina; y (6) una dinorfina.
MX2013008471A 2011-01-20 2012-01-19 Metodos y aparato para la deteccion de sensibilidad al gluten y su diferenciacion de la enfermedad celiaca. MX354089B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161434501P 2011-01-20 2011-01-20
PCT/US2012/021892 WO2012100070A2 (en) 2011-01-20 2012-01-19 Methods and apparatus for detection of gluten sensitivity, and its differentiation from celiac disease

Publications (2)

Publication Number Publication Date
MX2013008471A MX2013008471A (es) 2014-03-27
MX354089B true MX354089B (es) 2018-02-09

Family

ID=46516373

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013008471A MX354089B (es) 2011-01-20 2012-01-19 Metodos y aparato para la deteccion de sensibilidad al gluten y su diferenciacion de la enfermedad celiaca.

Country Status (12)

Country Link
US (3) US20120190571A1 (es)
EP (1) EP2666017B1 (es)
JP (4) JP5937106B2 (es)
KR (2) KR102047141B1 (es)
CN (2) CN107831318B (es)
AU (2) AU2012207267C1 (es)
BR (1) BR112013018696A2 (es)
CA (2) CA2827669C (es)
IL (2) IL227569B (es)
MX (1) MX354089B (es)
RU (2) RU2017137415A (es)
WO (1) WO2012100070A2 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2017137415A (ru) * 2011-01-20 2019-02-11 Иммьюносайнсиз Лаб, Инк. Способы и устройство для обнаружения глютеновой чувствительности и ее дифференцирования с целиакией
FR3004184B1 (fr) * 2013-02-26 2016-03-18 Agronomique Inst Nat Rech Anticorps anti-gluten desamide et utilisations.
FR3004183A1 (fr) * 2013-02-26 2014-10-10 Agronomique Inst Nat Rech Anticorps anti-gluten desamide et utilisations.
KR20150003059A (ko) * 2013-06-28 2015-01-08 김종배 뇨 중 글리아돌핀(Gliadorphin) 농도 측정을 위한 면역분석법
WO2017147378A1 (en) * 2016-02-25 2017-08-31 The Trustees Of Columbia University In The City Of New York Systemic immune activation and biomarkers of nonceliac wheat/gluten sensitivity
CN109313186A (zh) * 2016-04-26 2019-02-05 拜尔梅里科有限公司 克罗恩病敏感测试的组合物、设备以及方法
TW201832726A (zh) * 2016-11-01 2018-09-16 美商海科生醫有限責任公司 可基於輸入數據建議檢測之免疫檢測系統
CN108676863B (zh) * 2017-05-18 2022-05-03 四川出入境检验检疫局检验检疫技术中心 高通量测序技术鉴定小麦面粉中乳糜泻致敏原的方法
CN107176974B (zh) * 2017-06-06 2021-04-13 中国医学科学院北京协和医院 ω-5-醇溶蛋白特异的CD4+T细胞表位及其应用
CN110174513A (zh) * 2019-04-15 2019-08-27 中山大学附属第一医院 Tgm2在制备监测克罗恩病疾病活动的生物标志物中的应用
CN110055235A (zh) * 2019-05-14 2019-07-26 深圳市亚辉龙生物科技股份有限公司 用于转谷氨酰胺酶抗体检测的抗原及其制备方法、试剂盒及检测方法
JP2021084880A (ja) * 2019-11-28 2021-06-03 国立大学法人京都大学 ペプチド

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208479A (en) * 1977-07-14 1980-06-17 Syva Company Label modified immunoassays
US6596476B1 (en) * 1989-12-22 2003-07-22 Abbott Laboratories Hepatitis C assay
AU3596199A (en) * 1998-05-06 1999-11-23 Kobenhavns Universitet Treatment of celiac disease
US6103480A (en) * 1999-01-14 2000-08-15 Immunosciences Lab, Inc. Single blood test for detection of food allergy, candidiasis, microflora imbalance, intestinal barrier dysfunction and humoral immunodeficiencies
DE60011622T2 (de) * 1999-06-28 2005-09-08 Immundiagnostik Ag Diagnose der glutensensibilitätsenteropathie und anderer autoimmunerkrangungen
GB9919452D0 (en) * 1999-08-17 1999-10-20 Osteometer Biotech As Specific autoimmune reactions against isomerised/optically inverted epitopes:application for diagnosis of autoimmune diseases
GB9923306D0 (en) * 1999-10-01 1999-12-08 Isis Innovation Diagnostic and therapeutic epitope, and transgenic plant
CA2387359A1 (en) * 1999-10-20 2001-04-26 Immco Diagnostics Immunological assay for detection of antibodies in celiac disease
US6703208B1 (en) * 1999-10-20 2004-03-09 Immco Diagnostics Immunological assay for detection of antibodies in celiac disease
CU22968A1 (es) * 2000-06-07 2004-07-14 Ct Ingenieria Genetica Biotech Procedimiento para la detección de anticuerpos anti transglutaminasa con utilidad en el diagnóstico de la enfermedad celíaca
ATE439588T1 (de) * 2001-05-04 2009-08-15 Biosite Inc Diagnostische marker für akute herzerkrankungen und verfahren des gebrauchs
JP4958369B2 (ja) * 2001-09-05 2012-06-20 日本ハム株式会社 食物アレルゲン、食物アレルゲンの検出方法及び食物アレルギー誘発性食品の検出方法
US7320788B2 (en) * 2002-02-14 2008-01-22 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for Celiac Sprue
US7462688B2 (en) * 2002-05-14 2008-12-09 The Board Of Trustees Of The Leland Stanford Junior University Peptides for diagnostic and therapeutic methods for celiac sprue
US7252957B2 (en) * 2004-02-03 2007-08-07 Immunosciences Lab., Inc. Identification of etiology of autism
US7563864B2 (en) * 2004-04-26 2009-07-21 Celiac Sprue Research Foundation Prolyl endopeptidase mediated destruction of T cell epitopes in whole gluten
JP4157947B2 (ja) * 2004-10-29 2008-10-01 国立大学法人島根大学 小麦依存性運動誘発アナフィラキシーの判定方法
EP2594591B1 (en) * 2005-08-11 2018-06-06 Arpi Matossian-Rogers Tcr-v-beta related peptides for treatment and diagnosis of autoimmune disease
US8071101B2 (en) * 2005-11-03 2011-12-06 Avaxia Biologics, Inc. Antibody therapy for treatment of diseases associated with gluten intolerance
US20090176251A1 (en) * 2008-01-08 2009-07-09 Binder Walter L Methods for Diagnosing Celiac Disease Based on the Level of Anti-Gliadin and Anti-tTG IgA and IgG Antibodies
US20090253154A1 (en) * 2008-04-02 2009-10-08 Immunosciences Lab., Inc. Blood and saliva test for detection of delayed food allergy and intolerance against modified foods
CA3042826A1 (en) * 2008-11-30 2010-06-03 Immusant, Inc. Compositions and methods for treatment of celiac disease
HU0900199D0 (en) * 2009-04-01 2009-06-29 Debreceni Egyetem Diagnosis of gluten-induced autoimmune diseases
RU2017137415A (ru) * 2011-01-20 2019-02-11 Иммьюносайнсиз Лаб, Инк. Способы и устройство для обнаружения глютеновой чувствительности и ее дифференцирования с целиакией

Also Published As

Publication number Publication date
JP6426253B2 (ja) 2018-11-21
US20120190571A1 (en) 2012-07-26
CN107831318B (zh) 2021-06-18
AU2012207267A1 (en) 2013-09-12
CA3009238A1 (en) 2012-07-26
NZ614464A (en) 2015-04-24
KR20190087665A (ko) 2019-07-24
AU2017201908B2 (en) 2019-01-17
JP2018031793A (ja) 2018-03-01
CA2827669C (en) 2018-08-07
IL227569B (en) 2018-08-30
AU2012207267C1 (en) 2017-11-23
US20200057074A1 (en) 2020-02-20
EP2666017A2 (en) 2013-11-27
BR112013018696A2 (pt) 2016-10-18
JP6239685B2 (ja) 2017-11-29
CN103430025A (zh) 2013-12-04
WO2012100070A3 (en) 2012-12-06
IL227569A0 (en) 2013-09-30
RU2017137415A (ru) 2019-02-11
KR102047141B1 (ko) 2019-11-20
CN103430025B (zh) 2017-12-26
CN107831318A (zh) 2018-03-23
RU2635516C2 (ru) 2017-11-13
JP2019035761A (ja) 2019-03-07
RU2017137415A3 (es) 2019-02-11
AU2017201908A1 (en) 2017-04-13
KR20140032994A (ko) 2014-03-17
RU2013138482A (ru) 2015-02-27
US20160377629A1 (en) 2016-12-29
JP2014503079A (ja) 2014-02-06
CA3009238C (en) 2020-10-27
EP2666017A4 (en) 2014-11-19
EP2666017B1 (en) 2018-10-03
JP5937106B2 (ja) 2016-06-22
WO2012100070A2 (en) 2012-07-26
US10627408B2 (en) 2020-04-21
CA2827669A1 (en) 2012-07-26
AU2012207267B2 (en) 2016-12-22
JP2016176956A (ja) 2016-10-06
MX2013008471A (es) 2014-03-27
IL260991B (en) 2020-04-30

Similar Documents

Publication Publication Date Title
MX2013008471A (es) Metodos y aparatos para la deteccion de sensibilidad al gluten y su diferenciacion de la enfermedad celiaca.
Bodd et al. T-cell response to gluten in patients with HLA-DQ2. 2 reveals requirement of peptide-MHC stability in celiac disease
WO2007019411A3 (en) Peptides for diagnostic and therapeutic methods for celiac sprue
EA200971124A1 (ru) Множественный анализ образцов крови
IN2015DN03125A (es)
ATE554392T1 (de) Diagnoseverfahren für sprue/zöliakie
EA201070738A1 (ru) Композиции и способы детекции tiab
EP2566983A4 (en) SERIAL ANALYSIS OF BIOMARKERS FOR THE DIAGNOSIS OF A DISEASE
WO2010027903A3 (en) Lung cancer diagnosis
WO2012031122A3 (en) Methods and compositions for the diagnosis and treatment of cancer and autoimmune disorders
Slot et al. Immunochemical detection methods for gluten in food products: where do we go from here?
TW200801202A (en) Alpha-enolase specific antibody and method of use
NZ621733A (en) Lung cancer biomarkers and uses thereof
CA2855971C (en) Methods for detecting human papillomavirus and providing prognosis for head and neck squamous cell carcinoma
WO2012102535A3 (ko) 티로신 산화물이 결합된 바이오 물질을 포함하는 단백질 검출용 조성물
ATE514081T1 (de) T-zellen-testverfahren
WO2008073895A3 (en) Methods and devices for testing saliva
TW200622247A (en) Ileitis diagnostic assay
WO2015077382A3 (en) Combined cytology and molecular testing for early detection of esophageal adenocarcinoma
WO2012103337A3 (en) Assays and methods to sequence microbes directly from immune complexes
WO2009023331A3 (en) Antibodies and improved test sample handling methods for use in assays for myeloperoxidase
WO2011109112A3 (en) Method of detecting tau protein and tau fragments in serum
WO2006138324A3 (en) Treponema pallidum antigens for vaccine development and diagnostic tests
WO2012040264A3 (en) Diagnostic tests for immune reactivity with human endothelial cell growth factor
ATE412180T1 (de) Verfahren und mittel zum nachweis von durch gluten induzierten krankheiten

Legal Events

Date Code Title Description
GB Transfer or rights

Owner name: CYREX LABORATORIES, LLC

FG Grant or registration