MX2013008471A - Metodos y aparatos para la deteccion de sensibilidad al gluten y su diferenciacion de la enfermedad celiaca. - Google Patents

Metodos y aparatos para la deteccion de sensibilidad al gluten y su diferenciacion de la enfermedad celiaca.

Info

Publication number
MX2013008471A
MX2013008471A MX2013008471A MX2013008471A MX2013008471A MX 2013008471 A MX2013008471 A MX 2013008471A MX 2013008471 A MX2013008471 A MX 2013008471A MX 2013008471 A MX2013008471 A MX 2013008471A MX 2013008471 A MX2013008471 A MX 2013008471A
Authority
MX
Mexico
Prior art keywords
gliadin
mer
transglutaminase
glutenin
antigen
Prior art date
Application number
MX2013008471A
Other languages
English (en)
Other versions
MX354089B (es
Inventor
Aristo Vojdani
Original Assignee
Inmunosciences Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inmunosciences Lab Inc filed Critical Inmunosciences Lab Inc
Publication of MX2013008471A publication Critical patent/MX2013008471A/es
Publication of MX354089B publication Critical patent/MX354089B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/24—Immunology or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Los anticuerpos son utilizados como biomarcadores para ayudar a distinguir la reactividad y sensibilidad inmune al gluten, enfermedad celíaca silenciosa, enfermedad de Crohn y otras patologías relacionadas con el instinto de enfermedad celíaca clásica. En una clase de modalidades, sueros, saliva u otras muestras de un humano u otro animal son probados para los anticuerpos para (a) un antígeno de trigo; (b) un antígeno de gliadina; y (c) uno o más de una aglutinina de germen de trigo, una gluteomorfina, una glutenina, una glutenina des-amidada, una prodinorfina y una dinorfina. Los resultados de la prueba se consideran particularmente interesantes cuando el antígeno del trigo y el antígeno de la gliadina son ambos seleccionados del grupo que consiste de una a-gliadina-33-mer, una a-gliadina-17-mer, una ?-gliadina-15-mer, una ?-gliadina-17-mer, y una glutenina-21-mer. Las placas de prueba y kits pueden probarse ventajosamente para antígenos a por lo menos tres, cinco, siete o todas de a-gliadina, ?-gliadina, ?-gliadina, glutenina, aglutinina de germen de trigo, gluteomorfina, prodinorfinas, transglutaminasa-2, transglutaminasa-3, transglutaminasa-6 y transglutaminasa gliadina-unida.
MX2013008471A 2011-01-20 2012-01-19 Metodos y aparato para la deteccion de sensibilidad al gluten y su diferenciacion de la enfermedad celiaca. MX354089B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161434501P 2011-01-20 2011-01-20
PCT/US2012/021892 WO2012100070A2 (en) 2011-01-20 2012-01-19 Methods and apparatus for detection of gluten sensitivity, and its differentiation from celiac disease

Publications (2)

Publication Number Publication Date
MX2013008471A true MX2013008471A (es) 2014-03-27
MX354089B MX354089B (es) 2018-02-09

Family

ID=46516373

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013008471A MX354089B (es) 2011-01-20 2012-01-19 Metodos y aparato para la deteccion de sensibilidad al gluten y su diferenciacion de la enfermedad celiaca.

Country Status (12)

Country Link
US (3) US20120190571A1 (es)
EP (1) EP2666017B1 (es)
JP (4) JP5937106B2 (es)
KR (2) KR102047141B1 (es)
CN (2) CN107831318B (es)
AU (2) AU2012207267C1 (es)
BR (1) BR112013018696A2 (es)
CA (2) CA2827669C (es)
IL (2) IL227569B (es)
MX (1) MX354089B (es)
RU (2) RU2635516C2 (es)
WO (1) WO2012100070A2 (es)

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CN107831318B (zh) * 2011-01-20 2021-06-18 西瑞斯实验室有限公司 检测谷蛋白敏感性和其区分于乳糜泻的方法和装置
FR3004184B1 (fr) * 2013-02-26 2016-03-18 Agronomique Inst Nat Rech Anticorps anti-gluten desamide et utilisations.
FR3004183A1 (fr) * 2013-02-26 2014-10-10 Agronomique Inst Nat Rech Anticorps anti-gluten desamide et utilisations.
KR20150003059A (ko) * 2013-06-28 2015-01-08 김종배 뇨 중 글리아돌핀(Gliadorphin) 농도 측정을 위한 면역분석법
US11131676B2 (en) * 2016-02-25 2021-09-28 The Trustees Of Columbia University In The City Of New York Systemic immune activation and biomarkers of nonceliac wheat/gluten sensitivity
EP3449254B1 (en) * 2016-04-26 2024-08-28 Biomerica Inc. Compositions, devices, and methods of crohn's disease sensitivity testing
TW201832726A (zh) * 2016-11-01 2018-09-16 美商海科生醫有限責任公司 可基於輸入數據建議檢測之免疫檢測系統
CN108676863B (zh) * 2017-05-18 2022-05-03 四川出入境检验检疫局检验检疫技术中心 高通量测序技术鉴定小麦面粉中乳糜泻致敏原的方法
CN107176974B (zh) * 2017-06-06 2021-04-13 中国医学科学院北京协和医院 ω-5-醇溶蛋白特异的CD4+T细胞表位及其应用
CN110174513A (zh) * 2019-04-15 2019-08-27 中山大学附属第一医院 Tgm2在制备监测克罗恩病疾病活动的生物标志物中的应用
CN110055235A (zh) * 2019-05-14 2019-07-26 深圳市亚辉龙生物科技股份有限公司 用于转谷氨酰胺酶抗体检测的抗原及其制备方法、试剂盒及检测方法
JP2021084880A (ja) * 2019-11-28 2021-06-03 国立大学法人京都大学 ペプチド

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Also Published As

Publication number Publication date
WO2012100070A3 (en) 2012-12-06
JP5937106B2 (ja) 2016-06-22
CA3009238A1 (en) 2012-07-26
IL227569A0 (en) 2013-09-30
JP2019035761A (ja) 2019-03-07
JP2018031793A (ja) 2018-03-01
EP2666017A4 (en) 2014-11-19
NZ614464A (en) 2015-04-24
CA2827669C (en) 2018-08-07
US10627408B2 (en) 2020-04-21
US20200057074A1 (en) 2020-02-20
KR20140032994A (ko) 2014-03-17
RU2017137415A (ru) 2019-02-11
EP2666017B1 (en) 2018-10-03
CA3009238C (en) 2020-10-27
JP6426253B2 (ja) 2018-11-21
CN107831318B (zh) 2021-06-18
WO2012100070A2 (en) 2012-07-26
JP2014503079A (ja) 2014-02-06
US20120190571A1 (en) 2012-07-26
KR102047141B1 (ko) 2019-11-20
AU2012207267A1 (en) 2013-09-12
CA2827669A1 (en) 2012-07-26
RU2635516C2 (ru) 2017-11-13
IL260991B (en) 2020-04-30
RU2013138482A (ru) 2015-02-27
KR20190087665A (ko) 2019-07-24
CN103430025A (zh) 2013-12-04
AU2017201908A1 (en) 2017-04-13
JP2016176956A (ja) 2016-10-06
IL227569B (en) 2018-08-30
AU2012207267B2 (en) 2016-12-22
BR112013018696A2 (pt) 2016-10-18
JP6239685B2 (ja) 2017-11-29
EP2666017A2 (en) 2013-11-27
US20160377629A1 (en) 2016-12-29
AU2012207267C1 (en) 2017-11-23
RU2017137415A3 (es) 2019-02-11
CN107831318A (zh) 2018-03-23
AU2017201908B2 (en) 2019-01-17
MX354089B (es) 2018-02-09
CN103430025B (zh) 2017-12-26

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