WO2012102535A3 - 티로신 산화물이 결합된 바이오 물질을 포함하는 단백질 검출용 조성물 - Google Patents

티로신 산화물이 결합된 바이오 물질을 포함하는 단백질 검출용 조성물 Download PDF

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Publication number
WO2012102535A3
WO2012102535A3 PCT/KR2012/000560 KR2012000560W WO2012102535A3 WO 2012102535 A3 WO2012102535 A3 WO 2012102535A3 KR 2012000560 W KR2012000560 W KR 2012000560W WO 2012102535 A3 WO2012102535 A3 WO 2012102535A3
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WIPO (PCT)
Prior art keywords
composition
coupled
biomaterial
detecting proteins
proteins containing
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PCT/KR2012/000560
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English (en)
French (fr)
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WO2012102535A9 (ko
WO2012102535A2 (ko
Inventor
임국진
임진익
김범준
유경화
박수정
Original Assignee
(주)프로테옴텍
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Publication date
Application filed by (주)프로테옴텍 filed Critical (주)프로테옴텍
Priority to US13/981,037 priority Critical patent/US10041952B2/en
Priority to AU2012209627A priority patent/AU2012209627B2/en
Priority to CN2012800064680A priority patent/CN103339510A/zh
Publication of WO2012102535A2 publication Critical patent/WO2012102535A2/ko
Publication of WO2012102535A9 publication Critical patent/WO2012102535A9/ko
Publication of WO2012102535A3 publication Critical patent/WO2012102535A3/ko

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/583—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with non-fluorescent dye label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)

Abstract

본 발명은 티로신 산화물이 결합된 바이오 물질을 포함하는 단백질 검출용 조성물에 관한 것이다. 본 발명에 따른 티로신 산화물이 결합된 바이오 물질을 포함하는 단백질 검출용 조성물은 생체 내에 존재하는 천연 색소인 티로신 산화물을 바이오 물질에 결합하고, 상기 티로신 산화물이 결합된 바이오 물질을 단백질과 결합하여 단백질의 색상을 육안 또는 광학현미경으로 쉽게 확인함으로써, 다양한 질병을 간편하고 빠르게 진단할 수 있다. 따라서, 본 발명의 단백질 검출용 조성물은 수술장 내에서도 간편하고 빠르게 실시간으로 각종 질병을 진단할 수 있으며, 2차 항체 반응 및 최종 발색 단계가 필요 없어 기존의 조직검사법을 유용하게 대체할 수 있다.
PCT/KR2012/000560 2011-01-26 2012-01-20 티로신 산화물이 결합된 바이오 물질을 포함하는 단백질 검출용 조성물 WO2012102535A2 (ko)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US13/981,037 US10041952B2 (en) 2011-01-26 2012-01-20 Composition for detecting proteins containing tyrosine oxide-coupled biomaterial
AU2012209627A AU2012209627B2 (en) 2011-01-26 2012-01-20 Composition for detecting proteins containing tyrosine oxide-coupled biomaterial
CN2012800064680A CN103339510A (zh) 2011-01-26 2012-01-20 含有酪氨酸氧化物偶联的生物材料的用于检测蛋白质的组合物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2011-0007969 2011-01-26
KR1020110007969A KR101309789B1 (ko) 2011-01-26 2011-01-26 티로신 산화물이 결합된 바이오 물질을 포함하는 단백질 검출용 조성물

Publications (3)

Publication Number Publication Date
WO2012102535A2 WO2012102535A2 (ko) 2012-08-02
WO2012102535A9 WO2012102535A9 (ko) 2012-11-08
WO2012102535A3 true WO2012102535A3 (ko) 2012-12-27

Family

ID=46581274

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/000560 WO2012102535A2 (ko) 2011-01-26 2012-01-20 티로신 산화물이 결합된 바이오 물질을 포함하는 단백질 검출용 조성물

Country Status (5)

Country Link
US (1) US10041952B2 (ko)
KR (1) KR101309789B1 (ko)
CN (1) CN103339510A (ko)
AU (1) AU2012209627B2 (ko)
WO (1) WO2012102535A2 (ko)

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AR095399A1 (es) 2013-03-13 2015-10-14 Genentech Inc Formulaciones con oxidación reducida, método
US20140314778A1 (en) * 2013-03-13 2014-10-23 Genentech, Inc. Formulations with reduced oxidation
KR101696754B1 (ko) * 2016-05-02 2017-01-23 (주)큐브바이오 암 여부 및 암 종류의 측정이 가능한 티로신 검출 효소 이용 암 진단 장치
KR101685085B1 (ko) * 2016-05-03 2016-12-12 (주)큐브바이오 암 진단 키트
KR101696757B1 (ko) * 2016-05-13 2017-01-16 (주)큐브바이오 소변량 정밀 채취가 가능한 티로신 검출 효소 이용 멀티 암 진단 장치
KR101685091B1 (ko) * 2016-05-17 2016-12-12 (주)큐브바이오 고선명 윈도우를 갖는 암 진단 키트
KR101685089B1 (ko) * 2016-05-18 2016-12-12 (주)큐브바이오 휴대형 암 진단 키트
KR101707123B1 (ko) * 2016-05-18 2017-02-15 (주)큐브바이오 변기투입용 암 진단 도구 및 그것을 포함하는 자가 암 진단 시스템
KR101685086B1 (ko) * 2016-05-20 2016-12-12 (주)큐브바이오 암 마커 검출에 의한 암 진단 일괄 시스템
KR101694344B1 (ko) * 2016-05-23 2017-01-09 (주)큐브바이오 색상 왜곡 방지 구조의 윈도우를 갖는 암 진단 키트

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Also Published As

Publication number Publication date
US10041952B2 (en) 2018-08-07
WO2012102535A9 (ko) 2012-11-08
KR101309789B1 (ko) 2013-09-23
US20130302911A1 (en) 2013-11-14
CN103339510A (zh) 2013-10-02
KR20120086616A (ko) 2012-08-03
WO2012102535A2 (ko) 2012-08-02
AU2012209627B2 (en) 2016-04-14

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