MX351014B - Metodo para la prueba de disolucion de composiciones solidas que contienen enzimas digestivas. - Google Patents

Metodo para la prueba de disolucion de composiciones solidas que contienen enzimas digestivas.

Info

Publication number
MX351014B
MX351014B MX2014001492A MX2014001492A MX351014B MX 351014 B MX351014 B MX 351014B MX 2014001492 A MX2014001492 A MX 2014001492A MX 2014001492 A MX2014001492 A MX 2014001492A MX 351014 B MX351014 B MX 351014B
Authority
MX
Mexico
Prior art keywords
digestive enzymes
solid compositions
compositions containing
dissolution testing
containing digestive
Prior art date
Application number
MX2014001492A
Other languages
English (en)
Other versions
MX2014001492A (es
Inventor
Ortenzi Giovanni
Latino Massimo
Ghidorsi Luigi
Original Assignee
Aptalis Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aptalis Pharma Ltd filed Critical Aptalis Pharma Ltd
Publication of MX2014001492A publication Critical patent/MX2014001492A/es
Publication of MX351014B publication Critical patent/MX351014B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2545/00—Reactions characterised by their quantitative nature
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a un proceso para medir una cantidad de enzimas digestivas liberadas de una composición sólida de pancrelipasa en un medio de disolución que comprende utilizar espectroscopía de fluroescencia para medir la cantidad de enzimas digestivas liberadas de la composición en el medio de disolución.
MX2014001492A 2011-08-08 2012-08-08 Metodo para la prueba de disolucion de composiciones solidas que contienen enzimas digestivas. MX351014B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161521227P 2011-08-08 2011-08-08
PCT/IB2012/054050 WO2013021359A1 (en) 2011-08-08 2012-08-08 Method for dissolution testing of solid compositions containing digestive enzymes

Publications (2)

Publication Number Publication Date
MX2014001492A MX2014001492A (es) 2015-01-12
MX351014B true MX351014B (es) 2017-09-28

Family

ID=46970363

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014001492A MX351014B (es) 2011-08-08 2012-08-08 Metodo para la prueba de disolucion de composiciones solidas que contienen enzimas digestivas.

Country Status (18)

Country Link
US (1) US9976171B2 (es)
EP (2) EP2741766B1 (es)
JP (1) JP6004549B2 (es)
KR (1) KR101953413B1 (es)
CN (1) CN103732245B (es)
AU (2) AU2012293325B2 (es)
BR (1) BR112014002823A2 (es)
CA (1) CA2843556A1 (es)
CL (1) CL2014000315A1 (es)
CO (1) CO6890096A2 (es)
DK (1) DK2741766T3 (es)
ES (2) ES2558756T3 (es)
HU (1) HUE026560T2 (es)
IL (1) IL230616B (es)
MX (1) MX351014B (es)
RU (2) RU2602183C2 (es)
WO (1) WO2013021359A1 (es)
ZA (1) ZA201401650B (es)

Families Citing this family (10)

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ES2558756T3 (es) 2011-08-08 2016-02-08 Aptalis Pharma Limited Método para la prueba de disolución de composiciones sólidas que contienen enzimas digestivas
US10184121B2 (en) 2013-06-28 2019-01-22 Allergan Pharmaceuticals International Limited Methods for removing viral contaminants from pancreatic extracts
CA2919114A1 (en) * 2013-07-22 2015-02-12 Aptalis Pharma Ltd. High potency pancreatin pharmaceutical compositions
RU2679832C2 (ru) 2013-08-09 2019-02-13 Аллерган Фармасьютикалз Интернэйшнл Лимитед Композиция пищеварительных ферментов, подходящая для энтерального введения
CN110455932B (zh) * 2018-05-08 2022-04-22 人福普克药业（武汉）有限公司 一种测定贝莎罗汀软胶囊加酶溶出的方法
CA3241218A1 (en) * 2021-12-16 2023-06-22 Dinesh SRINIVASAN Stable lipase formulations and methods thereof

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AU2012293325B2 (en) 2015-05-07
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US9976171B2 (en) 2018-05-22
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HUE026560T2 (hu) 2016-06-28
US20140295474A1 (en) 2014-10-02
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EP2987499B1 (en) 2019-05-08
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RU2014104591A (ru) 2015-09-20
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CN103732245A (zh) 2014-04-16
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