MX349910B - Microorganismos modificados y métodos para elaborar butadieno utilizando los mismos. - Google Patents

Microorganismos modificados y métodos para elaborar butadieno utilizando los mismos.

Info

Publication number
MX349910B
MX349910B MX2014007235A MX2014007235A MX349910B MX 349910 B MX349910 B MX 349910B MX 2014007235 A MX2014007235 A MX 2014007235A MX 2014007235 A MX2014007235 A MX 2014007235A MX 349910 B MX349910 B MX 349910B
Authority
MX
Mexico
Prior art keywords
methods
same
butadiene
modified microorganisms
microorganisms
Prior art date
Application number
MX2014007235A
Other languages
English (en)
Other versions
MX2014007235A (es
Inventor
Schreiner Garcez Lopez Mateus
Michael Slovic Avram
Estrada Gouvea Iuri
Rincones Perez Johana
Penderson Parizzi Lucas
Original Assignee
Braskem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Braskem Sa filed Critical Braskem Sa
Publication of MX2014007235A publication Critical patent/MX2014007235A/es
Publication of MX349910B publication Critical patent/MX349910B/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01001—Alcohol dehydrogenase (1.1.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01127—Linalool dehydratase (4.2.1.127)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

La presente invención se refiere a microorganismos que comprenden uno o más polinucleótidos que codifican para enzimas en una o más trayectorias que catalizan una conversión de una fuente de carbono fermentable a butadieno. También se proporcionan métodos de uso de microorganismos en procesos industriales, que se incluyen, para uso en la producción de butadieno y productos derivados de los mismos. Un microorganismo genéticamente modificado, caracterizado porque comprende uno o más polinucleótidos que codifican para enzimas en una trayectoria que cataliza un conversión de una fuente de carbono fermentable a uno o más intermediarios en una trayectoria para la producción de butadieno y uno o más polinucleótidos que codifican para enzimas en una trayectoria que cataliza una conversión de uno o más intermediarios a butadieno, en donde uno o más intermediarios en la trayectoria para la producción de butadieno es crotonil-CoA, y en donde todas la enzimas se requieren ya sea de (i) crotonil-CoA reductasa (bifuncional) (E.C. 1.1.1), y deshidratasa de alcohol crotonílico (E.C. 4.2.1, 4.2.1.127) o (ii) crotonaldehído deshidrogenasa (E.C.1.2.1), deshidrogenasa de alcohol crotonílico (E.C.1.1.1, 1.1.1.1), y deshidratasa de alcohol crotonílico (E.C. 4.2.1, 4.2.1.127).
MX2014007235A 2011-12-16 2012-12-17 Microorganismos modificados y métodos para elaborar butadieno utilizando los mismos. MX349910B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161576788P 2011-12-16 2011-12-16
US201261606035P 2012-03-02 2012-03-02
PCT/US2012/070161 WO2013090915A1 (en) 2011-12-16 2012-12-17 Modified microorganisms and methods of making butadiene using same

Publications (2)

Publication Number Publication Date
MX2014007235A MX2014007235A (es) 2015-04-13
MX349910B true MX349910B (es) 2017-08-17

Family

ID=48613275

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014007235A MX349910B (es) 2011-12-16 2012-12-17 Microorganismos modificados y métodos para elaborar butadieno utilizando los mismos.

Country Status (14)

Country Link
US (3) US9518273B2 (es)
EP (1) EP2791342B1 (es)
JP (2) JP6415326B2 (es)
KR (1) KR20150068925A (es)
CN (2) CN104471068A (es)
AU (1) AU2012353654B2 (es)
BR (1) BR112014014652B1 (es)
CA (1) CA2859556C (es)
EC (1) ECSP14007092A (es)
MX (1) MX349910B (es)
PH (1) PH12014501364A1 (es)
RU (1) RU2639564C2 (es)
SG (1) SG11201403276TA (es)
WO (1) WO2013090915A1 (es)

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KR101929631B1 (ko) 2016-12-20 2018-12-14 서강대학교산학협력단 미생물 발효를 이용한 1,3-부타디엔의 제조 방법
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Also Published As

Publication number Publication date
JP2018134113A (ja) 2018-08-30
SG11201403276TA (en) 2014-10-30
AU2012353654B2 (en) 2016-09-29
CA2859556A1 (en) 2013-06-20
RU2014129026A (ru) 2016-02-10
CN104471068A (zh) 2015-03-25
US9518273B2 (en) 2016-12-13
US10273505B2 (en) 2019-04-30
BR112014014652B1 (pt) 2021-07-13
US10059963B2 (en) 2018-08-28
US20150152439A2 (en) 2015-06-04
ECSP14007092A (es) 2015-06-30
CN112877370A (zh) 2021-06-01
WO2013090915A1 (en) 2013-06-20
KR20150068925A (ko) 2015-06-22
US20160032325A1 (en) 2016-02-04
US20180346936A1 (en) 2018-12-06
CA2859556C (en) 2022-01-11
MX2014007235A (es) 2015-04-13
AU2012353654A8 (en) 2014-07-17
EP2791342A4 (en) 2016-04-13
US20140370564A1 (en) 2014-12-18
BR112014014652A2 (pt) 2017-06-13
JP2015501659A (ja) 2015-01-19
PH12014501364A1 (en) 2014-09-22
EP2791342A1 (en) 2014-10-22
AU2012353654A1 (en) 2014-07-10
EP2791342B1 (en) 2020-04-29
JP6415326B2 (ja) 2018-10-31
RU2639564C2 (ru) 2017-12-21

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