MX343604B - Disminuir nivel de lactato e incrementar producción de polipéptidos por regulación a la baja de la expresión de lactato dehidrogenasa y piruvato dehidrogenasa quinasa. - Google Patents

Disminuir nivel de lactato e incrementar producción de polipéptidos por regulación a la baja de la expresión de lactato dehidrogenasa y piruvato dehidrogenasa quinasa.

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Publication number
MX343604B
MX343604B MX2012013579A MX2012013579A MX343604B MX 343604 B MX343604 B MX 343604B MX 2012013579 A MX2012013579 A MX 2012013579A MX 2012013579 A MX2012013579 A MX 2012013579A MX 343604 B MX343604 B MX 343604B
Authority
MX
Mexico
Prior art keywords
ldh
pdhk
downregulating
polypeptide production
increasing polypeptide
Prior art date
Application number
MX2012013579A
Other languages
English (en)
Spanish (es)
Other versions
MX2012013579A (es
Inventor
Meixia Zhou
Bradley Richard Snedecor
Chi Kin Domingos Ng
Amy Shen
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45004831&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX343604(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2012013579A publication Critical patent/MX2012013579A/es
Publication of MX343604B publication Critical patent/MX343604B/es

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    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01027—L-Lactate dehydrogenase (1.1.1.27)
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MX2012013579A 2010-05-28 2011-05-26 Disminuir nivel de lactato e incrementar producción de polipéptidos por regulación a la baja de la expresión de lactato dehidrogenasa y piruvato dehidrogenasa quinasa. MX343604B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34972710P 2010-05-28 2010-05-28
PCT/US2011/038191 WO2011150241A2 (en) 2010-05-28 2011-05-26 Decreasing lactate level and increasing polypeptide production by downregulating the expression of lactate dehydrogenase and pyruvate dehydrogenase kinase

Publications (2)

Publication Number Publication Date
MX2012013579A MX2012013579A (es) 2013-01-24
MX343604B true MX343604B (es) 2016-11-11

Family

ID=45004831

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2012013579A MX343604B (es) 2010-05-28 2011-05-26 Disminuir nivel de lactato e incrementar producción de polipéptidos por regulación a la baja de la expresión de lactato dehidrogenasa y piruvato dehidrogenasa quinasa.
MX2016014767A MX374851B (es) 2010-05-28 2011-05-26 Disminuir nivel de lactato e incrementar produccion de polipeptidos por regulacion a la baja de la expresion de lactato dehidrogenasa y piruvato dehidrogenasa quinasa
MX2020009460A MX2020009460A (es) 2010-05-28 2012-11-22 Disminuir nivel de lactato e incrementar produccion de polipeptidos por regulacion a la baja de la expresion de lactato dehidrogenasa y piruvato dehidrogenasa quinasa.

Family Applications After (2)

Application Number Title Priority Date Filing Date
MX2016014767A MX374851B (es) 2010-05-28 2011-05-26 Disminuir nivel de lactato e incrementar produccion de polipeptidos por regulacion a la baja de la expresion de lactato dehidrogenasa y piruvato dehidrogenasa quinasa
MX2020009460A MX2020009460A (es) 2010-05-28 2012-11-22 Disminuir nivel de lactato e incrementar produccion de polipeptidos por regulacion a la baja de la expresion de lactato dehidrogenasa y piruvato dehidrogenasa quinasa.

Country Status (15)

Country Link
US (4) US9487809B2 (https=)
EP (1) EP2576580B1 (https=)
JP (3) JP6050226B2 (https=)
KR (3) KR101869987B1 (https=)
CN (1) CN102985437B (https=)
BR (1) BR112012030197A2 (https=)
CA (1) CA2800728C (https=)
DK (1) DK2576580T3 (https=)
ES (1) ES2599412T3 (https=)
HU (1) HUE030820T2 (https=)
MX (3) MX343604B (https=)
PL (1) PL2576580T3 (https=)
RU (1) RU2614125C2 (https=)
SI (1) SI2576580T1 (https=)
WO (1) WO2011150241A2 (https=)

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