WO2012102527A3 - 조절자 Ｔ 세포에 특이적으로 존재하는 새로운 표면단백질 Ｌｒｉｇ-1의 용도 - Google Patents

조절자 Ｔ 세포에 특이적으로 존재하는 새로운 표면단백질 Ｌｒｉｇ-1의 용도 Download PDF

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Publication number
WO2012102527A3
WO2012102527A3 PCT/KR2012/000532 KR2012000532W WO2012102527A3 WO 2012102527 A3 WO2012102527 A3 WO 2012102527A3 KR 2012000532 W KR2012000532 W KR 2012000532W WO 2012102527 A3 WO2012102527 A3 WO 2012102527A3
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WIPO (PCT)
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surface protein
regulatory
cell
specific surface
novel use
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PCT/KR2012/000532
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English (en)
French (fr)
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WO2012102527A2 (ko
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이상규
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Lee Sang-Kyou
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Priority to US14/427,421 priority Critical patent/US11655287B2/en
Publication of WO2012102527A2 publication Critical patent/WO2012102527A2/ko
Publication of WO2012102527A3 publication Critical patent/WO2012102527A3/ko
Priority to US16/233,738 priority patent/US11091538B2/en
Priority to US16/591,023 priority patent/US20200048335A1/en
Priority to US17/374,224 priority patent/US11932686B2/en
Priority to US17/575,039 priority patent/US20220135662A1/en

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Abstract

본 발명은 조절자 T 세포에 특이적으로 존재하는 표면단백질 Lrig-1의 새로운 용도에 관한 것이다. 보다 자세하게는 표면단백질 Lrig-1의 발현을 억제하는 siRNA를 포함하는 면역억제제에 관한 것이다. 또한, Lrig1의 단백질 또는 이 단백질을 코딩하는 유전자를 억제하는 면역억제제를 스크리닝하는 방법에 관한 것이다. 이를 통하여, 부작용이 적고 특이성이 높은 면역억제제를 개발할 수 있다.
PCT/KR2012/000532 2011-01-24 2012-01-20 조절자 Ｔ 세포에 특이적으로 존재하는 새로운 표면단백질 Ｌｒｉｇ-1의 용도 WO2012102527A2 (ko)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US14/427,421 US11655287B2 (en) 2011-01-24 2012-01-20 Use of regulatory T cell-specific surface protein LRIG-1
US16/233,738 US11091538B2 (en) 2011-01-24 2018-12-27 Use of regulatory T cell-specific surface protein LRIG-1
US16/591,023 US20200048335A1 (en) 2011-01-24 2019-10-02 Novel use of regulatory t cell-specific surface protein lrig-1
US17/374,224 US11932686B2 (en) 2011-01-24 2021-07-13 Use of regulatory T cell-specific surface protein LRIG-1
US17/575,039 US20220135662A1 (en) 2011-01-24 2022-01-13 Novel use of regulatory t cell-specific surface protein lrig-1

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2011-0007022 2011-01-24
KR1020110007022A KR101847523B1 (ko) 2011-01-24 2011-01-24 조절자 Ｔ 세포에 특이적으로 존재하는 새로운 표면단백질 Ｌｒｉｇ-1의 용도

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US14/427,421 A-371-Of-International US11655287B2 (en) 2011-01-24 2012-01-20 Use of regulatory T cell-specific surface protein LRIG-1
US16/233,738 Continuation US11091538B2 (en) 2011-01-24 2018-12-27 Use of regulatory T cell-specific surface protein LRIG-1
US16/591,023 Division US20200048335A1 (en) 2011-01-24 2019-10-02 Novel use of regulatory t cell-specific surface protein lrig-1

Publications (2)

Publication Number Publication Date
WO2012102527A2 WO2012102527A2 (ko) 2012-08-02
WO2012102527A3 true WO2012102527A3 (ko) 2012-12-20

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US (5) US11655287B2 (ko)
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WO (1) WO2012102527A2 (ko)

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KR101847523B1 (ko) * 2011-01-24 2018-05-28 연세대학교 산학협력단 조절자 Ｔ 세포에 특이적으로 존재하는 새로운 표면단백질 Ｌｒｉｇ-1의 용도
EP3613772A4 (en) * 2017-04-18 2020-12-30 Good T Cells, Inc. SPECIFIC BINDING MOLECULE FOR LRIG-1 PROTEIN AND ITS USE
US20210085785A1 (en) * 2018-02-23 2021-03-25 Truebinding, Inc. Treating cancer by blocking the interaction of vista and its binding partner
CN112041333A (zh) * 2018-04-26 2020-12-04 古德T细胞有限公司 新型融合蛋白和用于预防或治疗癌症的包含该融合蛋白的药物组合物
WO2019216675A1 (ko) * 2018-05-09 2019-11-14 주식회사 굳티셀 조절 t 세포 표면 항원의 에피토프 및 이에 특이적으로 결합하는 항체
US20210347849A1 (en) * 2018-07-24 2021-11-11 Good T Cells, Inc. Composition for Preventing or Treating Immune-Related Diseases
CN112912402A (zh) * 2018-10-17 2021-06-04 古德T细胞有限公司 Lrig-1蛋白的特异性结合分子及其用途
JP2022528045A (ja) * 2019-03-20 2022-06-08 グッド ティー セルズ、 インコーポレイテッド 脳神経系疾患の予防または治療用組成物
KR20210007916A (ko) * 2019-07-11 2021-01-20 주식회사 굳티셀 면역체크포인트 억제제 저항성 암의 예방, 개선 또는 치료용 조성물
US20220281973A1 (en) * 2019-08-29 2022-09-08 Truebinding, Inc. Antibodies and blocking the interaction of vista and its binding partner
KR20220053723A (ko) * 2020-10-22 2022-05-02 주식회사 굳티셀 활성화된 면역 세포의 세포 표면 항원 및 이의 다양한 용도

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US20210340235A1 (en) 2021-11-04
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US11655287B2 (en) 2023-05-23
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