MX2014004735A - Adicion de hierro para mejorar cultivo celular. - Google Patents

Adicion de hierro para mejorar cultivo celular.

Info

Publication number
MX2014004735A
MX2014004735A MX2014004735A MX2014004735A MX2014004735A MX 2014004735 A MX2014004735 A MX 2014004735A MX 2014004735 A MX2014004735 A MX 2014004735A MX 2014004735 A MX2014004735 A MX 2014004735A MX 2014004735 A MX2014004735 A MX 2014004735A
Authority
MX
Mexico
Prior art keywords
cell culture
iron
addition
improve cell
titer
Prior art date
Application number
MX2014004735A
Other languages
English (en)
Other versions
MX351991B (es
Inventor
Wenge Wang
Yen-Tung Luan
Denis Drapeau
Ryan P Nolan
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47324213&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2014004735(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of MX2014004735A publication Critical patent/MX2014004735A/es
Publication of MX351991B publication Critical patent/MX351991B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2511/00—Cells for large scale production

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención proporciona, entre otras cosas, métodos para incrementar la densidad celular, viabilidad y/o titulación en un cultivo celular que incluye las etapas de adicionar una composición que comprende hierro al cultivo celular.
MX2014004735A 2011-10-21 2012-10-09 Adicion de hierro para mejorar cultivo celular. MX351991B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161550058P 2011-10-21 2011-10-21
PCT/IB2012/055457 WO2013057628A1 (en) 2011-10-21 2012-10-09 Addition of iron to improve cell culture

Publications (2)

Publication Number Publication Date
MX2014004735A true MX2014004735A (es) 2014-07-28
MX351991B MX351991B (es) 2017-11-03

Family

ID=47324213

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014004735A MX351991B (es) 2011-10-21 2012-10-09 Adicion de hierro para mejorar cultivo celular.

Country Status (17)

Country Link
US (1) US20140322758A1 (es)
EP (1) EP2768944B2 (es)
JP (1) JP6400473B2 (es)
KR (2) KR20140077977A (es)
CN (1) CN103890166A (es)
AU (1) AU2012324495B2 (es)
BR (1) BR112014009379A2 (es)
CA (1) CA2852021C (es)
DK (1) DK2768944T3 (es)
ES (1) ES2784146T5 (es)
HK (1) HK1198657A1 (es)
IL (1) IL232171B (es)
MX (1) MX351991B (es)
RU (1) RU2663794C2 (es)
SG (2) SG10201702454YA (es)
WO (1) WO2013057628A1 (es)
ZA (1) ZA201402490B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200377918A1 (en) * 2017-03-31 2020-12-03 Boehringer Ingelheim International Gmbh Perfusion medium
EP4368698A1 (en) * 2022-11-09 2024-05-15 Sciperio, Inc. Optimized cell culture medium utilizing iron (iii) citrate as an iron delivery method for the in vitro, bioreactor-centric production of manufactured blood

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US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
AU2353384A (en) 1983-01-19 1984-07-26 Genentech Inc. Amplification in eukaryotic host cells
US4713339A (en) 1983-01-19 1987-12-15 Genentech, Inc. Polycistronic expression vector construction
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
JPS6147500A (ja) 1984-08-15 1986-03-07 Res Dev Corp Of Japan キメラモノクロ−ナル抗体及びその製造法
EP0173494A3 (en) 1984-08-27 1987-11-25 The Board Of Trustees Of The Leland Stanford Junior University Chimeric receptors by dna splicing and expression
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5166320A (en) 1987-04-22 1992-11-24 University Of Connecticut Carrier system and method for the introduction of genes into mammalian cells
US6291159B1 (en) 1989-05-16 2001-09-18 Scripps Research Institute Method for producing polymers having a preselected activity
JPH0396383A (ja) 1989-09-08 1991-04-22 Riso Kagaku Corp 画像形成装置
ATE236249T1 (de) 1989-09-12 2003-04-15 Hoffmann La Roche Tfn-bindende proteine
DE69032483T2 (de) 1989-10-05 1998-11-26 Optein Inc Zellfreie synthese und isolierung von genen und polypeptiden
US6657103B1 (en) 1990-01-12 2003-12-02 Abgenix, Inc. Human antibodies derived from immunized xenomice
GB9021679D0 (en) 1990-10-05 1990-11-21 Gorman Scott David Antibody preparation
GB9022545D0 (en) 1990-10-17 1990-11-28 Wellcome Found Culture medium
DE4115722A1 (de) * 1991-05-14 1992-11-19 Boehringer Mannheim Gmbh Serumfreies medium zur kultivierung von saeugerzellen
WO1993000423A1 (en) * 1991-06-21 1993-01-07 Novo Nordisk A/S Iron chelate culture medium additive
GB9215834D0 (en) 1992-07-24 1992-09-09 Celltech Ltd Cell culture
US6310185B1 (en) 1994-03-08 2001-10-30 Memorial Sloan Kettering Cancer Center Recombinant human anti-Lewis Y antibodies
EP2218775B1 (en) * 1996-08-30 2015-01-28 Life Technologies Corporation Method for producing a polypeptide in vitro in mammalian cells in a protein-free and serum-free culture medium
TWI329129B (en) 2001-02-08 2010-08-21 Wyeth Corp Modified and stabilized gdf propeptides and uses thereof
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EA011749B1 (ru) * 2004-11-02 2009-06-30 Арес Трейдинг С.А. Способ продуцирования гормона роста человека и применение среды, не содержащей сыворотки, для культивирования клеток млекопитающих, экспрессирующих гормон роста человека
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Also Published As

Publication number Publication date
EP2768944B2 (en) 2023-11-22
RU2014115731A (ru) 2015-11-27
ES2784146T5 (es) 2024-06-04
RU2663794C2 (ru) 2018-08-09
CA2852021C (en) 2018-08-28
CA2852021A1 (en) 2013-04-25
ZA201402490B (en) 2015-11-25
KR20170021919A (ko) 2017-02-28
HK1198657A1 (en) 2015-05-22
IL232171B (en) 2018-07-31
AU2012324495B2 (en) 2016-04-21
AU2012324495A1 (en) 2014-04-24
JP6400473B2 (ja) 2018-10-03
BR112014009379A2 (pt) 2017-04-18
CN103890166A (zh) 2014-06-25
EP2768944B1 (en) 2020-02-26
SG11201401220SA (en) 2014-07-30
JP2014530620A (ja) 2014-11-20
KR20140077977A (ko) 2014-06-24
EP2768944A1 (en) 2014-08-27
ES2784146T3 (es) 2020-09-22
WO2013057628A1 (en) 2013-04-25
IL232171A0 (en) 2014-06-30
SG10201702454YA (en) 2017-05-30
US20140322758A1 (en) 2014-10-30
DK2768944T3 (da) 2020-04-20
MX351991B (es) 2017-11-03

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