MX338151B - Composiciones de anticuerpo recombinante anti-receptor de factor de crecimiento epidermico. - Google Patents
Composiciones de anticuerpo recombinante anti-receptor de factor de crecimiento epidermico.Info
- Publication number
- MX338151B MX338151B MX2011011163A MX2011011163A MX338151B MX 338151 B MX338151 B MX 338151B MX 2011011163 A MX2011011163 A MX 2011011163A MX 2011011163 A MX2011011163 A MX 2011011163A MX 338151 B MX338151 B MX 338151B
- Authority
- MX
- Mexico
- Prior art keywords
- antibodies
- antibody compositions
- growth factor
- factor receptor
- epidermal growth
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 102000009465 Growth Factor Receptors Human genes 0.000 title 1
- 108010009202 Growth Factor Receptors Proteins 0.000 title 1
- 229940116977 epidermal growth factor Drugs 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 101000851181 Homo sapiens Epidermal growth factor receptor Proteins 0.000 abstract 1
- 238000010171 animal model Methods 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000011712 cell development Effects 0.000 abstract 1
- 230000008029 eradication Effects 0.000 abstract 1
- 102000045108 human EGFR Human genes 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 238000011275 oncology therapy Methods 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/54—F(ab')2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200700317 | 2007-03-01 | ||
| US90477307P | 2007-03-05 | 2007-03-05 | |
| DKPA200701016 | 2007-07-10 | ||
| US92972707P | 2007-07-11 | 2007-07-11 | |
| PCT/DK2008/050047 WO2008104183A2 (en) | 2007-03-01 | 2008-02-27 | Recombinant anti-epidermal growth factor receptor antibody compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX338151B true MX338151B (es) | 2016-04-05 |
Family
ID=39495833
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009008909A MX2009008909A (es) | 2007-03-01 | 2008-02-27 | Composiciones de anticuerpo recombinante anti-receptor de factor de crecimiento epidermico. |
| MX2011011163A MX338151B (es) | 2007-03-01 | 2008-02-27 | Composiciones de anticuerpo recombinante anti-receptor de factor de crecimiento epidermico. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009008909A MX2009008909A (es) | 2007-03-01 | 2008-02-27 | Composiciones de anticuerpo recombinante anti-receptor de factor de crecimiento epidermico. |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US7887805B2 (OSRAM) |
| EP (2) | EP2132229B1 (OSRAM) |
| JP (1) | JP5726417B2 (OSRAM) |
| KR (2) | KR101805140B1 (OSRAM) |
| CN (2) | CN101675075B (OSRAM) |
| AU (1) | AU2008221118B2 (OSRAM) |
| BR (1) | BRPI0808551B1 (OSRAM) |
| CA (1) | CA2676049C (OSRAM) |
| DK (1) | DK2132229T3 (OSRAM) |
| ES (1) | ES2582386T3 (OSRAM) |
| HK (1) | HK1197252A1 (OSRAM) |
| IL (2) | IL199725A (OSRAM) |
| MX (2) | MX2009008909A (OSRAM) |
| NZ (2) | NZ597466A (OSRAM) |
| PL (1) | PL2132229T3 (OSRAM) |
| RU (1) | RU2013119724A (OSRAM) |
| TW (1) | TWI426083B (OSRAM) |
| WO (1) | WO2008104183A2 (OSRAM) |
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| US7612181B2 (en) | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
| ATE521704T1 (de) * | 2007-03-01 | 2011-09-15 | Symphogen As | Verfahren zur klonierung verwandter antikörper |
| KR101805140B1 (ko) | 2007-03-01 | 2017-12-05 | 심포젠 에이/에스 | 재조합 항-표피 성장 인자 수용체 항체 조성물 |
| JP2008289483A (ja) * | 2007-05-25 | 2008-12-04 | Symphogen As | 真核生物系において発現可能な形質転換体のスクリーニング |
| WO2009030239A1 (en) * | 2007-09-06 | 2009-03-12 | Genmab A/S | Novel methods and antibodies for treating cancer |
| US20090203038A1 (en) * | 2007-12-27 | 2009-08-13 | Abbott Laboratories | Negative Mimic Antibody For Use as a Blocking Reagent In BNP Immunoassays |
| EP2331689A4 (en) * | 2008-08-29 | 2012-10-31 | Symphogen As | METHOD OF CLONING AVIAN ORIGIN ANTIBODIES |
| RU2540146C2 (ru) * | 2008-08-29 | 2015-02-10 | Симфоген А/С | Композиции рекомбинантных антител против рецептора эпидермального фактора роста |
| US20110224094A1 (en) * | 2008-10-06 | 2011-09-15 | Symphogen A/S | Method for identifying and selecting drug candidates for combinatorial drug products |
| FR2942928B1 (fr) | 2009-03-03 | 2011-04-01 | Alcatel Lucent | Procede et systeme de gestion multicriteres de notifications de presence |
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| CN102687020A (zh) * | 2009-10-09 | 2012-09-19 | 西福根有限公司 | 利用特征肽和质谱对混合物中的单个重组蛋白进行多重定量 |
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| US8609095B2 (en) | 2010-03-04 | 2013-12-17 | Symphogen A/S | Anti-HER2 antibodies and compositions |
| WO2011137114A1 (en) * | 2010-04-26 | 2011-11-03 | Abraxis Bioscience, Llc | Sparc binding antibodies and uses thereof |
| KR20130060223A (ko) * | 2010-05-04 | 2013-06-07 | 메리맥 파마슈티컬즈, 인크. | 상피세포 성장인자 수용체(egfr)에 대한 항체 및 이의 용도 |
| WO2011140151A1 (en) * | 2010-05-04 | 2011-11-10 | Dyax Corp. | Antibodies against epidermal growth factor receptor (egfr) |
| WO2012018260A1 (en) * | 2010-08-05 | 2012-02-09 | Universiteit Utrecht Holding B.V. | Epidermal growth factor receptor targeted immune therapy |
| AU2011320314B2 (en) | 2010-10-29 | 2015-08-06 | Immunogen, Inc. | Novel EGFR-binding molecules and immunoconjugates thereof |
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| KR101862832B1 (ko) * | 2010-11-01 | 2018-05-30 | 심포젠 에이/에스 | Pan―her 항체 조성물 |
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| WO2012097313A2 (en) | 2011-01-14 | 2012-07-19 | The Regents Of The University Of California | Therapeutic antibodies against ror-1 protein and methods for use of same |
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| KR20190107761A (ko) | 2011-03-09 | 2019-09-20 | 셀 시그널링 테크놀러지, 인크. | 모노클로날 항체를 생성하는 방법 및 시약 |
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| HK1202431A1 (en) | 2012-05-02 | 2015-10-02 | Symphogen A/S | Humanized pan-her antibody compositions |
| US20140065655A1 (en) * | 2012-09-05 | 2014-03-06 | Scivax Corporation | Screening method for substance acting on maintenance of epithelial properties of cell |
| US20150293105A1 (en) * | 2012-10-26 | 2015-10-15 | The University Of Queensland | Methods for classifying tumors and uses therefor |
| CN102993305B (zh) * | 2012-11-16 | 2015-05-13 | 上海赛伦生物技术有限公司 | 人源抗人表皮生长因子受体抗体及其编码基因与应用 |
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| WO2015112749A2 (en) * | 2014-01-22 | 2015-07-30 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for antibody and antibody-loaded dendritic cell mediated therapy |
| GB201402591D0 (en) * | 2014-02-14 | 2014-04-02 | Memo Therapeutics Ag | Method for recovering two or more genes, or gene products, encoding an immunoreceptor |
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| PL3253865T3 (pl) * | 2015-02-06 | 2022-10-10 | National University Of Singapore | Sposoby wzmacniania skuteczności terapeutycznych komórek odpornościowych |
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-
2008
- 2008-02-27 KR KR1020167031076A patent/KR101805140B1/ko not_active Expired - Fee Related
- 2008-02-27 EP EP08706941.5A patent/EP2132229B1/en active Active
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- 2008-02-27 CN CN200880006835.0A patent/CN101675075B/zh active Active
- 2008-02-27 WO PCT/DK2008/050047 patent/WO2008104183A2/en not_active Ceased
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