MX260952B - - Google Patents

Info

Publication number
MX260952B
MX260952B MXPA05001024A MX260952B MX 260952 B MX260952 B MX 260952B MX PA05001024 A MXPA05001024 A MX PA05001024A MX 260952 B MX260952 B MX 260952B
Authority
MX
Mexico
Application number
Other languages
Spanish (es)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10233723A external-priority patent/DE10233723A1/de
Application filed filed Critical
Publication of MXPA05001024A publication Critical patent/MXPA05001024A/es
Publication of MX260952B publication Critical patent/MX260952B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J11/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/06—Hydroxylating
    • C12P33/08—Hydroxylating at 11 position
    • C12P33/10—Hydroxylating at 11 position at 11 alpha-position
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/12—Acting on D ring
    • C12P33/16—Acting at 17 position

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Reproductive Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MXPA05001024A 2002-07-24 2003-07-24 Metodo microbiologico para la produccion de 11 alfa-hdiroxiesteroides sustituidos en la posicion 7 alfa. MXPA05001024A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10233723A DE10233723A1 (de) 2002-07-24 2002-07-24 Mikrobiologische Verfahren zur Herstellung von 7α-substituierten 11α-Hydroxysteroiden, daraus herstellbare 7α,17α-substituierte 11β-Halogensteroide, deren Herstellungsverfahren und Verwendung sowie pharmazeutische Präparate, die diese Verbindungen enthalten, sowie daraus herstellbare 7α-substituierte Estra-1,3,5(10)-triene
US40295302P 2002-08-14 2002-08-14
PCT/EP2003/008111 WO2004011663A2 (de) 2002-07-24 2003-07-24 Mikrobiologische verfahren zur herstellung von 7alpha-substituierten 11alpha-hydroxysteroiden

Publications (2)

Publication Number Publication Date
MXPA05001024A MXPA05001024A (es) 2005-05-16
MX260952B true MX260952B (de) 2008-10-01

Family

ID=31189296

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05001024A MXPA05001024A (es) 2002-07-24 2003-07-24 Metodo microbiologico para la produccion de 11 alfa-hdiroxiesteroides sustituidos en la posicion 7 alfa.

Country Status (19)

Country Link
EP (1) EP1523568A2 (de)
JP (1) JP4417838B2 (de)
KR (1) KR101041328B1 (de)
CN (1) CN100339486C (de)
BR (1) BR0313210A (de)
CA (1) CA2492079C (de)
CO (1) CO5690563A2 (de)
CR (1) CR7672A (de)
EA (2) EA010572B1 (de)
EC (1) ECSP055630A (de)
HR (1) HRP20050172A2 (de)
IL (1) IL166358A0 (de)
MX (1) MXPA05001024A (de)
NO (1) NO20050980L (de)
NZ (2) NZ549529A (de)
PH (1) PH12005500143B1 (de)
PL (1) PL373808A1 (de)
RS (1) RS51855B (de)
WO (1) WO2004011663A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101296936B (zh) * 2005-10-27 2011-06-22 大鹏药品工业株式会社 生产甾族化合物的方法
RU2377309C1 (ru) * 2008-04-22 2009-12-27 Валентина Александровна Андрюшина МИКРОБИОЛОГИЧЕСКИЙ СПОСОБ ПОЛУЧЕНИЯ 7α-ГИДРОКСИАНДРОСТЕНОВ
CN103834712B (zh) * 2012-11-26 2016-03-30 复旦大学 去氧孕烯中间体纳米脂质体生物转化的优化方法
CN103214543B (zh) * 2012-12-25 2015-09-02 中国人民解放军海军医学研究所 新山楂酸衍生物、其制备方法及其在抗肿瘤药物中的应用
CN104862323B (zh) * 2015-06-02 2018-01-16 中国农业科学院生物技术研究所 修饰苯二酚类化合物的羟化酶基因
PL246071B1 (pl) * 2022-08-26 2024-11-25 Wrocław University Of Environmental And Life Sciences Sposób wytwarzania 11α-hydroksy-19-nortestosteronu

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL75841C (de) 1949-06-11
US2658023A (en) * 1953-04-21 1953-11-03 Pfizer & Co C Oxygenation of steroids
US2985563A (en) * 1958-11-13 1961-05-23 Schering Corp 11alpha-hydroxylation of steroids by glomerella
US3004047A (en) * 1959-03-13 1961-10-10 Olin Mathieson 6alpha-halo-11alpha-hydroxy steroids of the pregnane series and esters thereof
US3341557A (en) 1961-06-05 1967-09-12 Upjohn Co 7-methyltestosterones
US3203869A (en) * 1962-10-11 1965-08-31 Syntex Corp 11alpha-hydroxylation of 6-substituted-11-desoxy steroids with microorganisms of thegenus fusarium, liseola section
US5342834A (en) 1989-04-07 1994-08-30 The Population Council, Inc. Method for androgen supplementation
EP1167380A3 (de) * 1995-12-11 2004-12-08 G.D. Searle & Co. 11.alpha.-Hydroxy-Steroid-4,6-dien-3-on Verbindungen und ein Verfahren zu ihrer Herstellung
PL185223B1 (pl) * 1995-12-12 2003-04-30 Akzo Nobel Nv Mikrobiologiczny sposób in vitro transformacji steroidów w ich 11alfa-hydroksyanalogi
GB9525194D0 (en) 1995-12-12 1996-02-07 Zeneca Ltd Pharmaceutical composition
US20020012694A1 (en) * 1997-09-17 2002-01-31 Alfred J. Moo-Young Transdermal administration of ment
US6767902B2 (en) 1997-09-17 2004-07-27 The Population Council, Inc. Androgen as a male contraceptive and non-contraceptive androgen replacement
US5952319A (en) 1997-11-26 1999-09-14 Research Triangle Institute Androgenic steroid compounds and a method of making and using the same
RU2002124602A (ru) 2000-02-15 2004-03-10 Шеринг Акциенгезелльшафт (De) Композиция для мужской контрацепции, включающая норэтистерон
DE10104327A1 (de) * 2001-01-24 2002-07-25 Schering Ag 11beta-Halogensteroide, deren Herstellung und Verwendung zur Herstellung von Arzneimitteln sowie 11beta-Halogensteroide enthaltende pharmazeutische Präparate
EP1524983B1 (de) * 2002-07-25 2008-01-02 Bayer Schering Pharma Aktiengesellschaft Zusammensetzung, enthaltend ein androgenes 11-b-halogensteroid und ein gestagen sowie m nnliches kontrazeptivum auf basis dieser zusammensetzung

Also Published As

Publication number Publication date
ECSP055630A (es) 2005-04-18
BR0313210A (pt) 2005-06-28
EA010572B1 (ru) 2008-10-30
NZ537871A (en) 2006-10-27
JP2006503813A (ja) 2006-02-02
EA200500224A1 (ru) 2005-08-25
JP4417838B2 (ja) 2010-02-17
RS51855B (sr) 2012-02-29
CO5690563A2 (es) 2006-10-31
PL373808A1 (en) 2005-09-19
NO20050980L (no) 2005-02-23
AU2003281677A1 (en) 2004-02-16
WO2004011663A3 (de) 2004-07-15
CN100339486C (zh) 2007-09-26
MXPA05001024A (es) 2005-05-16
EA008147B1 (ru) 2007-04-27
WO2004011663A9 (de) 2004-05-06
KR101041328B1 (ko) 2011-06-14
EP1523568A2 (de) 2005-04-20
PH12005500143B1 (en) 2011-03-25
EA200601030A1 (ru) 2006-10-27
NZ549529A (en) 2008-04-30
RS20050045A (sr) 2007-06-04
KR20050026507A (ko) 2005-03-15
HK1081999A1 (zh) 2006-05-26
WO2004011663A2 (de) 2004-02-05
CA2492079A1 (en) 2004-02-05
CR7672A (es) 2006-05-29
IL166358A0 (en) 2006-01-16
CA2492079C (en) 2012-01-10
HRP20050172A2 (en) 2005-04-30
CN1671858A (zh) 2005-09-21

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GD Licence granted
FG Grant or registration
HC Change of company name or juridical status