MX2020011941A - Variantes de quimosina con propiedades de coagulacion de leche mejoradas. - Google Patents

Variantes de quimosina con propiedades de coagulacion de leche mejoradas.

Info

Publication number
MX2020011941A
MX2020011941A MX2020011941A MX2020011941A MX2020011941A MX 2020011941 A MX2020011941 A MX 2020011941A MX 2020011941 A MX2020011941 A MX 2020011941A MX 2020011941 A MX2020011941 A MX 2020011941A MX 2020011941 A MX2020011941 A MX 2020011941A
Authority
MX
Mexico
Prior art keywords
chymosin
variants
improved milk
clotting properties
clotting
Prior art date
Application number
MX2020011941A
Other languages
English (en)
Inventor
Martin Lund
Jonas Jacobsen
Sari Charlotte Hansen
Iben Jeppesen
Den Brink Johannes Maarten Van
Original Assignee
Chr Hansen As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48577692&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2020011941(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chr Hansen As filed Critical Chr Hansen As
Publication of MX2020011941A publication Critical patent/MX2020011941A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C11/00—Milk substitutes, e.g. coffee whitener compositions
    • A23C11/02—Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins
    • A23C11/10—Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins containing or not lactose but no other milk components as source of fats, carbohydrates or proteins
    • A23C11/103—Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins containing or not lactose but no other milk components as source of fats, carbohydrates or proteins containing only proteins from pulses, oilseeds or nuts, e.g. nut milk
    • A23C11/106—Addition of, or treatment with, microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C19/00—Cheese; Cheese preparations; Making thereof
    • A23C19/02—Making cheese curd
    • A23C19/032—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin
    • A23C19/0326—Rennet produced by fermentation, e.g. microbial rennet; Rennet produced by genetic engineering
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C20/00—Cheese substitutes
    • A23C20/02—Cheese substitutes containing neither milk components, nor caseinate, nor lactose, as sources of fats, proteins or carbohydrates
    • A23C20/025—Cheese substitutes containing neither milk components, nor caseinate, nor lactose, as sources of fats, proteins or carbohydrates mainly containing proteins from pulses or oilseeds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/1203—Addition of, or treatment with, enzymes or microorganisms other than lactobacteriaceae
    • A23C9/1209—Proteolytic or milk coagulating enzymes, e.g. trypsine
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L11/00—Pulses, i.e. fruits of leguminous plants, for production of food; Products from legumes; Preparation or treatment thereof
    • A23L11/40—Pulse curds
    • A23L11/45—Soy bean curds, e.g. tofu
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L11/00—Pulses, i.e. fruits of leguminous plants, for production of food; Products from legumes; Preparation or treatment thereof
    • A23L11/60—Drinks from legumes, e.g. lupine drinks
    • A23L11/65—Soy drinks
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • C12N9/6483—Chymosin (3.4.23.4), i.e. rennin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/23—Aspartic endopeptidases (3.4.23)
    • C12Y304/23004—Chymosin (3.4.23.4), i.e. rennin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2330/00—Production
    • C12N2330/50—Biochemical production, i.e. in a transformed host cell

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Botany (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Animal Husbandry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Dairy Products (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

Se describen variantes de quimosina con propiedades de coagulación de leche mejoradas.
MX2020011941A 2012-05-25 2014-11-24 Variantes de quimosina con propiedades de coagulacion de leche mejoradas. MX2020011941A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12169503 2012-05-25

Publications (1)

Publication Number Publication Date
MX2020011941A true MX2020011941A (es) 2021-01-15

Family

ID=48577692

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2014014300A MX366610B (es) 2012-05-25 2013-05-22 Variantes de quimosina con propiedades de coagulacion de leche mejoradas.
MX2020011941A MX2020011941A (es) 2012-05-25 2014-11-24 Variantes de quimosina con propiedades de coagulacion de leche mejoradas.
MX2019008255A MX2019008255A (es) 2012-05-25 2014-11-24 Variantes de quimosina con propiedades de coagulacion de leche mejoradas.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2014014300A MX366610B (es) 2012-05-25 2013-05-22 Variantes de quimosina con propiedades de coagulacion de leche mejoradas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2019008255A MX2019008255A (es) 2012-05-25 2014-11-24 Variantes de quimosina con propiedades de coagulacion de leche mejoradas.

Country Status (19)

Country Link
US (2) US9930899B2 (es)
EP (3) EP2855674B2 (es)
JP (3) JP2015518718A (es)
KR (2) KR102245756B1 (es)
CN (2) CN104487572B (es)
AU (3) AU2013265343B2 (es)
BR (2) BR112014029012B1 (es)
CA (3) CA3201812A1 (es)
DK (2) DK2855674T4 (es)
ES (1) ES2741723T5 (es)
FI (1) FI2855674T4 (es)
HK (1) HK1202894A1 (es)
MX (3) MX366610B (es)
NZ (4) NZ742660A (es)
PL (2) PL2855674T5 (es)
RU (2) RU2019108268A (es)
TR (1) TR201910420T4 (es)
UA (2) UA118956C2 (es)
WO (1) WO2013174840A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX366610B (es) 2012-05-25 2019-07-16 Chr Hansen As Variantes de quimosina con propiedades de coagulacion de leche mejoradas.
UA121380C2 (uk) * 2014-02-26 2020-05-25 Кр. Гансен А/С Поліпептид хімозину з удосконаленими властивостями щодо згортання молока
KR20170115614A (ko) 2015-02-10 2017-10-17 시에이치알. 한센 에이/에스 개선된 응유 특성을 갖는 키모신 배합물
EP4079849A1 (en) 2015-06-22 2022-10-26 Chr. Hansen A/S Variants of chymosin with improved properties
CN108135193A (zh) * 2015-08-31 2018-06-08 科.汉森有限公司 具有改善性质的凝乳酶的变体
CA3024210C (en) * 2016-05-19 2024-03-19 Chr. Hansen A/S Variants of chymosin with improved milk-clotting properties
AR108526A1 (es) 2016-05-19 2018-08-29 Chr Hansen As Variantes de quimosina con propiedades mejoradas de coagulación de la leche
CN106754840B (zh) * 2016-12-22 2019-06-21 江南大学 一种酶活及热稳定性改善的凝乳酶突变体
BR112020013771A2 (pt) 2018-01-15 2020-12-01 Chr. Hansen A/S produto de leite fermentado e preparação deste utilizando fosfolipase
CN111172139B (zh) * 2020-02-27 2021-11-30 武汉轻工大学 一种小牛皱胃凝乳酶及基因与菌株和应用
CN113801867B (zh) * 2021-11-18 2022-03-18 中国农业科学院生物技术研究所 骆驼凝乳酶原突变蛋白及其编码基因和应用
WO2023194285A2 (en) 2022-04-06 2023-10-12 Chr. Hansen A/S Aspartic protease, methods and uses thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI841288A (fi) 1983-03-31 1984-10-01 Codon Genetic Eng Lab Rekombinant-dna-kod foer uttryckning av polypeptid.
US7390936B1 (en) 1999-08-23 2008-06-24 Sembiosys Genetics Inc. Commercial production of chymosin in plants
RU2192137C2 (ru) * 2000-08-07 2002-11-10 Открытое акционерное общество "Уфамолагропром" Способ производства сыра
WO2002036752A2 (en) 2000-11-06 2002-05-10 Chr. Hansen A/S Method of producing non-bovine chymosin and use thereof
EP1608947A4 (en) 2002-10-02 2009-06-17 Catalyst Biosciences Inc PROCESS FOR PRODUCING AND TESTING FOR PROTEASES WITH CHANGED SPECIFICITY
EP1660655B1 (en) 2003-06-27 2016-11-02 Bioren, LLC Look-through mutagenesis
US7482148B2 (en) 2004-03-30 2009-01-27 Sudershan Biotech Ltd. Recombinant calf-chymosin and a process for producing the same
US20110008492A1 (en) 2007-02-13 2011-01-13 Chr. Hansen A/S Coagulation of milk
JP2010046034A (ja) 2008-08-22 2010-03-04 Toyota Central R&D Labs Inc 変異体のスクリーニング方法
WO2010110464A1 (en) 2009-03-24 2010-09-30 Meito Sangyo Co., Ltd. Improved type milk-clotting protease derived from a microorganism
CA2872309C (en) † 2012-05-03 2021-03-02 Dsm Ip Assets B.V. Improved chymosine enzyme variants
MX366610B (es) 2012-05-25 2019-07-16 Chr Hansen As Variantes de quimosina con propiedades de coagulacion de leche mejoradas.
UA121380C2 (uk) 2014-02-26 2020-05-25 Кр. Гансен А/С Поліпептид хімозину з удосконаленими властивостями щодо згортання молока
KR20170115614A (ko) 2015-02-10 2017-10-17 시에이치알. 한센 에이/에스 개선된 응유 특성을 갖는 키모신 배합물
EP4079849A1 (en) 2015-06-22 2022-10-26 Chr. Hansen A/S Variants of chymosin with improved properties
CN108135193A (zh) 2015-08-31 2018-06-08 科.汉森有限公司 具有改善性质的凝乳酶的变体
CA3024210C (en) 2016-05-19 2024-03-19 Chr. Hansen A/S Variants of chymosin with improved milk-clotting properties
AR108526A1 (es) 2016-05-19 2018-08-29 Chr Hansen As Variantes de quimosina con propiedades mejoradas de coagulación de la leche

Also Published As

Publication number Publication date
DK3604509T3 (da) 2021-05-25
AU2022200663A1 (en) 2022-02-24
MX2019008255A (es) 2020-01-15
HK1202894A1 (en) 2015-10-09
KR102245756B1 (ko) 2021-04-29
RU2683385C2 (ru) 2019-03-28
ES2741723T5 (es) 2023-01-23
DK2855674T3 (da) 2019-06-24
CA2874214C (en) 2021-02-16
KR102419515B1 (ko) 2022-07-11
EP2855674B1 (en) 2019-05-15
CN110714001A (zh) 2020-01-21
FI2855674T4 (fi) 2023-01-13
JP2018148926A (ja) 2018-09-27
EP3604509A1 (en) 2020-02-05
EP3604509B1 (en) 2021-03-31
MX366610B (es) 2019-07-16
CA2874214A1 (en) 2013-11-28
NZ702030A (en) 2016-11-25
CN104487572B (zh) 2019-12-13
DK2855674T4 (da) 2022-11-21
AU2019203589B2 (en) 2021-11-04
ES2741723T3 (es) 2020-02-12
UA118956C2 (uk) 2019-04-10
KR20210048580A (ko) 2021-05-03
AU2019203589A1 (en) 2019-06-13
JP2020058367A (ja) 2020-04-16
RU2014152723A (ru) 2016-07-20
EP3929288A1 (en) 2021-12-29
RU2019108268A (ru) 2019-04-23
CA3100606A1 (en) 2013-11-28
JP2015518718A (ja) 2015-07-06
US20180317510A1 (en) 2018-11-08
PL2855674T3 (pl) 2019-11-29
PL3604509T3 (pl) 2021-09-13
EP2855674B2 (en) 2022-11-02
AU2013265343A1 (en) 2014-12-04
BR112014029012B1 (pt) 2022-05-03
CA3100606C (en) 2023-08-01
MX2014014300A (es) 2015-02-12
PL2855674T5 (pl) 2023-03-27
KR20150015014A (ko) 2015-02-09
TR201910420T4 (tr) 2019-08-21
EP2855674A1 (en) 2015-04-08
US10806157B2 (en) 2020-10-20
BR112014029012A2 (pt) 2017-06-27
US9930899B2 (en) 2018-04-03
AU2013265343B2 (en) 2019-02-21
UA126330C2 (uk) 2022-09-21
NZ742745A (en) 2019-12-20
US20150173383A1 (en) 2015-06-25
CA3201812A1 (en) 2013-11-28
NZ725398A (en) 2018-05-25
NZ742660A (en) 2019-12-20
BR122021019895B1 (pt) 2022-10-25
CN104487572A (zh) 2015-04-01
RU2019108268A3 (es) 2021-11-29
WO2013174840A1 (en) 2013-11-28

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