MX2022006692A - Variantes de quimosina con propiedades mejoradas de coagulacion de la leche. - Google Patents

Variantes de quimosina con propiedades mejoradas de coagulacion de la leche.

Info

Publication number
MX2022006692A
MX2022006692A MX2022006692A MX2022006692A MX2022006692A MX 2022006692 A MX2022006692 A MX 2022006692A MX 2022006692 A MX2022006692 A MX 2022006692A MX 2022006692 A MX2022006692 A MX 2022006692A MX 2022006692 A MX2022006692 A MX 2022006692A
Authority
MX
Mexico
Prior art keywords
chymosin
variants
improved milk
clotting properties
clotting
Prior art date
Application number
MX2022006692A
Other languages
English (en)
Inventor
Martin Lund
Jonas Jacobsen
Iben Jeppesen
Den Brink Johannes Maarten Van
Jesper Langholm Jensen
Christian Jaeckel
Original Assignee
Chr Hansen As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chr Hansen As filed Critical Chr Hansen As
Publication of MX2022006692A publication Critical patent/MX2022006692A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C19/00—Cheese; Cheese preparations; Making thereof
    • A23C19/02—Making cheese curd
    • A23C19/04—Making cheese curd characterised by the use of specific enzymes of vegetable or animal origin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • C12N9/6483—Chymosin (3.4.23.4), i.e. rennin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C19/00—Cheese; Cheese preparations; Making thereof
    • A23C19/02—Making cheese curd
    • A23C19/04—Making cheese curd characterised by the use of specific enzymes of vegetable or animal origin
    • A23C19/041—Proteolytic or milk clotting enzymes from plants or vegetables, e.g. papain, ficin, bromelain
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/1203—Addition of, or treatment with, enzymes or microorganisms other than lactobacteriaceae
    • A23C9/1209—Proteolytic or milk coagulating enzymes, e.g. trypsine
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A23K20/147—Polymeric derivatives, e.g. peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/23—Aspartic endopeptidases (3.4.23)
    • C12Y304/23004—Chymosin (3.4.23.4), i.e. rennin

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Husbandry (AREA)
  • Botany (AREA)
  • Peptides Or Proteins (AREA)
  • Dairy Products (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Fodder In General (AREA)
  • Beans For Foods Or Fodder (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Se describen las variantes de quimosina con propiedades mejoradas de coagulación de leche.
MX2022006692A 2014-02-26 2016-07-29 Variantes de quimosina con propiedades mejoradas de coagulacion de la leche. MX2022006692A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14156707 2014-02-26
EP14176664 2014-07-11

Publications (1)

Publication Number Publication Date
MX2022006692A true MX2022006692A (es) 2022-07-11

Family

ID=52596486

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016009937A MX2016009937A (es) 2014-02-26 2015-02-26 Variantes de quimosina con propiedades mejoradas de coagulacion de la leche.
MX2022006692A MX2022006692A (es) 2014-02-26 2016-07-29 Variantes de quimosina con propiedades mejoradas de coagulacion de la leche.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2016009937A MX2016009937A (es) 2014-02-26 2015-02-26 Variantes de quimosina con propiedades mejoradas de coagulacion de la leche.

Country Status (13)

Country Link
US (4) US10982204B2 (es)
EP (1) EP3110948A1 (es)
JP (3) JP7098270B2 (es)
KR (2) KR102494645B1 (es)
CN (2) CN106062187B (es)
AU (2) AU2015222149B2 (es)
BR (1) BR112016017502B1 (es)
CA (1) CA2938015A1 (es)
MX (2) MX2016009937A (es)
NZ (1) NZ722003A (es)
RU (2) RU2739004C1 (es)
UA (1) UA121380C2 (es)
WO (1) WO2015128417A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3929288A1 (en) 2012-05-25 2021-12-29 Chr. Hansen A/S Variants of chymosin with improved milk-clotting properties
KR102494645B1 (ko) 2014-02-26 2023-02-06 시에이치알. 한센 에이/에스 개선된 응유 특성을 갖는 키모신 변이체
DK3310914T3 (da) * 2015-06-22 2022-06-20 Chr Hansen As Chymosinvarianter med forbedrede egenskaber
CA2995755A1 (en) * 2015-08-31 2017-03-09 Chr. Hansen A/S Variants of chymosin with improved properties
EP3143879A1 (en) * 2015-09-18 2017-03-22 DSM IP Assets B.V. Yogurt with reduced ripening
WO2017198810A1 (en) 2016-05-19 2017-11-23 Chr. Hansen A/S Variants of chymosin with improved milk-clotting properties
US10961524B2 (en) 2016-05-19 2021-03-30 Chr. Hansen A/S Variants of chymosin with improved milk-clotting properties
CN106754840B (zh) * 2016-12-22 2019-06-21 江南大学 一种酶活及热稳定性改善的凝乳酶突变体
JP7455062B2 (ja) 2018-01-15 2024-03-25 セーホーエル．ハンセン アクティーゼルスカブ ホスホリパーゼを用いた発酵乳製品及びその調製物
CN113801867B (zh) * 2021-11-18 2022-03-18 中国农业科学院生物技术研究所 骆驼凝乳酶原突变蛋白及其编码基因和应用
AU2023249315A1 (en) 2022-04-06 2024-09-26 Chr. Hansen A/S Aspartic protease, methods and uses thereof
WO2024189187A1 (en) 2023-03-15 2024-09-19 Dsm Ip Assets B.V. Novel process for producing a fermented milk product and new fermented milk product so produced

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0123928A3 (en) 1983-03-31 1986-02-05 Codon Genetic Engineering Laboratories Recombinant dna coding for a polypeptide displaying milk clotting activity
US7390936B1 (en) * 1999-08-23 2008-06-24 Sembiosys Genetics Inc. Commercial production of chymosin in plants
RU2192137C2 (ru) 2000-08-07 2002-11-10 Открытое акционерное общество "Уфамолагропром" Способ производства сыра
DK2365069T3 (en) 2000-11-06 2018-04-23 Eidgenoessisch Technische Hochschule Zuerich Process for the preparation of non-bovine chymosin and its use
KR20100109969A (ko) 2002-10-02 2010-10-11 카탈리스트 바이오사이언시즈, 인코포레이티드 변경된 특이성을 갖는 프로테아제의 제조 및 선별 방법
WO2004072225A2 (en) 2003-02-12 2004-08-26 Ramot At Tel Aviv University Ltd. Transgenic fungi expressing bcl-2 and methods of using bcl-2 or portions thereof for improving biomass production, survival, longevity, stress resistance and pathogenicity of fungi
ES2609102T3 (es) 2003-06-27 2017-04-18 Bioren, LLC Mutagénesis por revisión
WO2005094185A2 (en) * 2004-03-30 2005-10-13 Sudershan Biotech Limited Recombinant calf-chymosin and a process for producing the same
WO2008098973A1 (en) 2007-02-13 2008-08-21 Chr. Hansen A/S Coagulation of milk
JP2010046034A (ja) 2008-08-22 2010-03-04 Toyota Central R&D Labs Inc 変異体のスクリーニング方法
ES2445710T3 (es) * 2009-03-24 2014-03-04 Meito Sangyo Co., Ltd. Proteasa coagulante de la leche de tipo mejorado derivada de un microorganismo
EP2599863B1 (en) * 2009-11-20 2017-08-02 Danisco US Inc. Beta-glucosidase variants with improved properties
AU2011289833C1 (en) * 2010-07-12 2017-06-15 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Histidyl-tRNA synthetases
WO2013164481A1 (en) * 2012-05-03 2013-11-07 Dsm Ip Assets B.V. Improved enzyme variants
EP3929288A1 (en) 2012-05-25 2021-12-29 Chr. Hansen A/S Variants of chymosin with improved milk-clotting properties
CN103484488B (zh) * 2013-09-16 2015-07-15 中国农业科学院生物技术研究所 优化的牛凝乳酶原基因及其分泌表达方法和应用
KR102494645B1 (ko) 2014-02-26 2023-02-06 시에이치알. 한센 에이/에스 개선된 응유 특성을 갖는 키모신 변이체
WO2016128476A1 (en) 2015-02-10 2016-08-18 Chr. Hansen A/S Blends of chymosins with improved milk-clotting properties
DK3310914T3 (da) 2015-06-22 2022-06-20 Chr Hansen As Chymosinvarianter med forbedrede egenskaber
CA2995755A1 (en) 2015-08-31 2017-03-09 Chr. Hansen A/S Variants of chymosin with improved properties
WO2017198810A1 (en) 2016-05-19 2017-11-23 Chr. Hansen A/S Variants of chymosin with improved milk-clotting properties
US10961524B2 (en) 2016-05-19 2021-03-30 Chr. Hansen A/S Variants of chymosin with improved milk-clotting properties

Also Published As

Publication number Publication date
BR112016017502A2 (es) 2017-08-08
US20170067041A1 (en) 2017-03-09
AU2021286442A1 (en) 2022-01-20
JP2017512059A (ja) 2017-05-18
EP3110948A1 (en) 2017-01-04
RU2739004C1 (ru) 2020-12-21
US11629343B2 (en) 2023-04-18
BR112016017502B1 (pt) 2023-10-24
KR102344861B1 (ko) 2021-12-29
KR102494645B1 (ko) 2023-02-06
CN111944791A (zh) 2020-11-17
RU2717770C2 (ru) 2020-03-25
AU2015222149B2 (en) 2021-09-23
US20220154162A1 (en) 2022-05-19
CA2938015A1 (en) 2015-09-03
AU2015222149A1 (en) 2016-07-28
US11827913B2 (en) 2023-11-28
KR20220002714A (ko) 2022-01-06
MX2016009937A (es) 2016-10-31
US20240084281A1 (en) 2024-03-14
US10982204B2 (en) 2021-04-20
JP2020141667A (ja) 2020-09-10
CN106062187B (zh) 2020-09-15
WO2015128417A1 (en) 2015-09-03
CN106062187A (zh) 2016-10-26
RU2016132974A (ru) 2018-03-27
JP7098270B2 (ja) 2022-07-11
US20210230571A1 (en) 2021-07-29
JP2022122926A (ja) 2022-08-23
JP7144470B2 (ja) 2022-09-29
UA121380C2 (uk) 2020-05-25
KR20160125459A (ko) 2016-10-31
RU2016132974A3 (es) 2018-09-18
NZ722003A (en) 2023-06-30

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