MX2020008925A - Composicion oftalmica que comprende dicuafosol y polimero cationico. - Google Patents
Composicion oftalmica que comprende dicuafosol y polimero cationico.Info
- Publication number
- MX2020008925A MX2020008925A MX2020008925A MX2020008925A MX2020008925A MX 2020008925 A MX2020008925 A MX 2020008925A MX 2020008925 A MX2020008925 A MX 2020008925A MX 2020008925 A MX2020008925 A MX 2020008925A MX 2020008925 A MX2020008925 A MX 2020008925A
- Authority
- MX
- Mexico
- Prior art keywords
- cationic
- copolymers
- hydrolyzed
- diquafosol
- cationic polymer
- Prior art date
Links
- 229920006317 cationic polymer Polymers 0.000 title abstract 3
- NMLMACJWHPHKGR-NCOIDOBVSA-N P(1),P(4)-bis(uridin-5'-yl) tetraphosphate Chemical compound N1([C@@H]2O[C@@H]([C@H]([C@H]2O)O)COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@H]([C@@H](O2)N2C(NC(=O)C=C2)=O)O)O)C=CC(=O)NC1=O NMLMACJWHPHKGR-NCOIDOBVSA-N 0.000 title abstract 2
- 229950003529 diquafosol Drugs 0.000 title abstract 2
- 125000002091 cationic group Chemical group 0.000 abstract 8
- 229920001577 copolymer Polymers 0.000 abstract 5
- WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical compound OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 abstract 4
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 abstract 2
- 229920001661 Chitosan Polymers 0.000 abstract 2
- 235000011037 adipic acid Nutrition 0.000 abstract 2
- 239000001361 adipic acid Substances 0.000 abstract 2
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 abstract 1
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010035532 Collagen Proteins 0.000 abstract 1
- 239000004593 Epoxy Substances 0.000 abstract 1
- 102000011782 Keratins Human genes 0.000 abstract 1
- 108010076876 Keratins Proteins 0.000 abstract 1
- 108010073771 Soybean Proteins Proteins 0.000 abstract 1
- 229920006322 acrylamide copolymer Polymers 0.000 abstract 1
- 235000019270 ammonium chloride Nutrition 0.000 abstract 1
- 239000005018 casein Substances 0.000 abstract 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 abstract 1
- 235000021240 caseins Nutrition 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 125000004386 diacrylate group Chemical group 0.000 abstract 1
- -1 diallyl quaternary ammonium salt Chemical class 0.000 abstract 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229920001519 homopolymer Polymers 0.000 abstract 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920005573 silicon-containing polymer Polymers 0.000 abstract 1
- 235000019710 soybean protein Nutrition 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018035578 | 2018-02-28 | ||
| PCT/JP2019/007542 WO2019168023A1 (ja) | 2018-02-28 | 2019-02-27 | ジクアホソルおよびカチオン性ポリマーを含有する眼科用組成物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2020008925A true MX2020008925A (es) | 2020-10-01 |
Family
ID=67806273
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2020008925A MX2020008925A (es) | 2018-02-28 | 2019-02-27 | Composicion oftalmica que comprende dicuafosol y polimero cationico. |
| MX2022014791A MX2022014791A (es) | 2018-02-28 | 2020-08-26 | Composicion oftalmica que comprende dicuafosol y polimero cationico. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022014791A MX2022014791A (es) | 2018-02-28 | 2020-08-26 | Composicion oftalmica que comprende dicuafosol y polimero cationico. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20210000844A1 (https=) |
| EP (1) | EP3760207A4 (https=) |
| JP (5) | JP6716800B2 (https=) |
| KR (3) | KR102796051B1 (https=) |
| CN (2) | CN117137866A (https=) |
| BR (1) | BR112020017661A2 (https=) |
| CA (1) | CA3091700A1 (https=) |
| EA (1) | EA202092030A1 (https=) |
| MX (2) | MX2020008925A (https=) |
| PH (1) | PH12020551313B1 (https=) |
| SG (1) | SG11202007977RA (https=) |
| TW (4) | TWI898399B (https=) |
| UA (1) | UA129517C2 (https=) |
| WO (1) | WO2019168023A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117137866A (zh) * | 2018-02-28 | 2023-12-01 | 参天制药株式会社 | 含有地夸磷索及阳离子性聚合物的眼科用组合物 |
| ES2994624T3 (en) * | 2019-02-27 | 2025-01-27 | Santen Pharmaceutical Co Ltd | Ophthalmic composition containing diquafosol or salt thereof, vinyl-based polymer and cellulose-based polymer |
| JP6966667B2 (ja) * | 2019-08-27 | 2021-11-17 | 参天製薬株式会社 | ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物 |
| KR102365008B1 (ko) * | 2020-06-23 | 2022-02-23 | 주식회사태준제약 | 디쿠아포솔을 포함하는 점안 조성물 |
| JP7230169B2 (ja) * | 2020-12-25 | 2023-02-28 | 参天製薬株式会社 | ジクアホソルまたはその塩、銀塩およびイオン性等張化剤を含有する水性点眼液 |
| CN113712910A (zh) * | 2021-08-05 | 2021-11-30 | 广州市桐晖药业有限公司 | 一种滴眼液及其制备方法 |
| JPWO2023054669A1 (https=) * | 2021-09-30 | 2023-04-06 | ||
| KR102794468B1 (ko) | 2022-04-04 | 2025-04-14 | 서울대학교산학협력단 | 감미 억제용 조성물 및 식품의 감미 억제 방법 |
| KR20250038935A (ko) * | 2023-09-13 | 2025-03-20 | 루다큐어 주식회사 | 8-옥소-2'-데옥시구아노신 또는 이의 약학적으로 허용가능한 염을 포함하는 수용액 형태의 점안제 |
| KR20250160050A (ko) | 2024-05-03 | 2025-11-11 | 삼천당제약주식회사 | 물리화학적 특성이 개선된 안구건조증 예방 또는 치료용 약학 조성물 |
| CN119970633A (zh) * | 2025-03-26 | 2025-05-13 | 苏州乐珠制药有限公司 | 一种地夸磷索钠滴眼液及其制备方法 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01294620A (ja) | 1988-05-19 | 1989-11-28 | Kissei Pharmaceut Co Ltd | 水溶液製剤およびその製造方法 |
| US5358706A (en) * | 1992-09-30 | 1994-10-25 | Union Carbide Chemicals & Plastics Technology Corporation | Muco-adhesive polymers |
| US5422116A (en) * | 1994-02-18 | 1995-06-06 | Ciba-Geigy Corporation | Liquid ophthalmic sustained release delivery system |
| JP3155689B2 (ja) * | 1995-08-10 | 2001-04-16 | 昭和薬品化工株式会社 | 消炎点眼剤 |
| US5900407A (en) * | 1997-02-06 | 1999-05-04 | Inspire Pharmaceuticals, Inc. | Method of treating dry eye disease with uridine triphosphates and related compounds |
| WO1999005155A2 (en) | 1997-07-25 | 1999-02-04 | Inspire Pharmaceuticals, Inc. | Salts of di(uridine 5'-tetraphosphate), method for preparation and uses thereof |
| JP2001294620A (ja) | 2000-04-11 | 2001-10-23 | Showa Denko Kk | プラスチックレンズ材料、該材料の製造方法、プラスチックレンズ用組成物、該組成物を硬化してなるプラスチックレンズ、及び該プラスチックレンズの製造方法 |
| AU2001260643B9 (en) * | 2000-05-30 | 2006-10-19 | Merck Sharp & Dohme Corp. | Ectocornea extension promoters |
| KR20070114130A (ko) * | 2005-02-14 | 2007-11-29 | 존슨 앤드 존슨 비젼 케어, 인코포레이티드 | 착용감이 편안한 안용 장치 및 이의 제조방법 |
| JP4515960B2 (ja) | 2005-05-19 | 2010-08-04 | 株式会社資生堂 | 整髪料洗浄剤及びその使用方法 |
| KR100870104B1 (ko) * | 2005-11-28 | 2008-11-26 | 주식회사 머젠스 | 안구건조증 치료 및 예방용 조성물 |
| JP5421272B2 (ja) * | 2007-10-12 | 2014-02-19 | リゾルヴィクス・ファーマシューティカルズ・インコーポレイテッド | 眼病治療のための組成物及び方法 |
| BRPI0909797A2 (pt) * | 2008-03-07 | 2017-08-22 | Sun Pharma Advanced Res Co Ltd | Composição oftálmica |
| UA113839C2 (xx) * | 2010-12-28 | 2017-03-27 | Очний розчин, який містить диквафозол, спосіб його отримання і спосіб інгібування утворення нерозчинного осаду | |
| KR101536885B1 (ko) * | 2012-03-26 | 2015-07-14 | 산텐 세이야꾸 가부시키가이샤 | 디쿠아포솔 함유 점안액 |
| EP3139903B1 (en) * | 2014-05-07 | 2019-07-03 | Croma-Pharma Gesellschaft m.b.H. | Aqueous ophthalmic solution and method for treating dry eye syndrome |
| WO2015190483A1 (ja) * | 2014-06-10 | 2015-12-17 | ロート製薬株式会社 | 眼科用水性組成物 |
| KR102330736B1 (ko) * | 2014-12-25 | 2021-11-23 | 산텐 세이야꾸 가부시키가이샤 | 수성 점안액 |
| KR101587385B1 (ko) * | 2015-07-29 | 2016-01-21 | 국제약품공업주식회사 | 사이클로스포린 함유 무자극성의 안약조성물 및 편리한 제조방법 |
| WO2017033967A1 (ja) * | 2015-08-24 | 2017-03-02 | 参天製薬株式会社 | 眼科用フィルム製剤 |
| PT3266446T (pt) * | 2016-07-07 | 2019-01-30 | Salvat Lab Sa | Composição oftálmica compreendendo óleo de rícino e triglicérido de cadeia média |
| CN106772747B (zh) * | 2016-12-26 | 2022-10-18 | 深圳市光科全息技术有限公司 | 一种光学膜及其制作方法 |
| RU2710366C1 (ru) * | 2017-04-25 | 2019-12-26 | Вакамото Фармасьютикал Ко., Лтд. | Термочувствительная гелеобразующая искусственная слеза |
| JP6582029B2 (ja) * | 2017-10-03 | 2019-09-25 | 株式会社メニコン | 眼科用組成液及びその使用方法 |
| CN117137866A (zh) * | 2018-02-28 | 2023-12-01 | 参天制药株式会社 | 含有地夸磷索及阳离子性聚合物的眼科用组合物 |
| CN108853016A (zh) * | 2018-09-26 | 2018-11-23 | 广州大光制药有限公司 | 一种地夸磷索钠滴眼液及其制备方法 |
| ES2994624T3 (en) * | 2019-02-27 | 2025-01-27 | Santen Pharmaceutical Co Ltd | Ophthalmic composition containing diquafosol or salt thereof, vinyl-based polymer and cellulose-based polymer |
| JP6966667B2 (ja) | 2019-08-27 | 2021-11-17 | 参天製薬株式会社 | ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物 |
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2019
- 2019-02-27 CN CN202311151214.4A patent/CN117137866A/zh active Pending
- 2019-02-27 BR BR112020017661-3A patent/BR112020017661A2/pt not_active IP Right Cessation
- 2019-02-27 CN CN201980015357.8A patent/CN111757742B/zh active Active
- 2019-02-27 TW TW113102160A patent/TWI898399B/zh active
- 2019-02-27 KR KR1020227041383A patent/KR102796051B1/ko active Active
- 2019-02-27 JP JP2020503563A patent/JP6716800B2/ja active Active
- 2019-02-27 TW TW114131509A patent/TW202600146A/zh unknown
- 2019-02-27 US US16/976,504 patent/US20210000844A1/en not_active Abandoned
- 2019-02-27 TW TW108106730A patent/TWI781296B/zh active
- 2019-02-27 UA UAA202006163A patent/UA129517C2/uk unknown
- 2019-02-27 KR KR1020207027473A patent/KR102472773B1/ko active Active
- 2019-02-27 EP EP19759990.5A patent/EP3760207A4/en active Pending
- 2019-02-27 PH PH1/2020/551313A patent/PH12020551313B1/en unknown
- 2019-02-27 CA CA3091700A patent/CA3091700A1/en active Pending
- 2019-02-27 SG SG11202007977RA patent/SG11202007977RA/en unknown
- 2019-02-27 EA EA202092030A patent/EA202092030A1/ru unknown
- 2019-02-27 WO PCT/JP2019/007542 patent/WO2019168023A1/ja not_active Ceased
- 2019-02-27 MX MX2020008925A patent/MX2020008925A/es unknown
- 2019-02-27 TW TW111140996A patent/TWI833406B/zh active
- 2019-02-27 KR KR1020257011738A patent/KR20250053220A/ko active Pending
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2020
- 2020-06-10 JP JP2020100953A patent/JP7297718B2/ja active Active
- 2020-08-26 MX MX2022014791A patent/MX2022014791A/es unknown
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2022
- 2022-07-21 JP JP2022116528A patent/JP7472202B2/ja active Active
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2024
- 2024-02-13 JP JP2024019332A patent/JP7796782B2/ja active Active
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2025
- 2025-12-18 JP JP2025264248A patent/JP2026034664A/ja active Pending
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