MX2020008925A - Composicion oftalmica que comprende dicuafosol y polimero cationico. - Google Patents

Composicion oftalmica que comprende dicuafosol y polimero cationico.

Info

Publication number
MX2020008925A
MX2020008925A MX2020008925A MX2020008925A MX2020008925A MX 2020008925 A MX2020008925 A MX 2020008925A MX 2020008925 A MX2020008925 A MX 2020008925A MX 2020008925 A MX2020008925 A MX 2020008925A MX 2020008925 A MX2020008925 A MX 2020008925A
Authority
MX
Mexico
Prior art keywords
cationic
copolymers
hydrolyzed
diquafosol
cationic polymer
Prior art date
Application number
MX2020008925A
Other languages
English (en)
Inventor
Asuka Kamimura
Kenichi Endo
Kyohei Takahashi
Hiroyuki Asada
Kenji Morishima
Yusuke Momokawa
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Publication of MX2020008925A publication Critical patent/MX2020008925A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Se proporciona una composición oftálmica que comprende dicuafosol o una sal del mismo y un polímero catiónico, siendo el polímero catiónico al menos uno seleccionado del grupo que consiste de quitosan, un derivado de quitosan, un copolímero de (met)acrilato catiónico, un polímero de silicona catiónica, un copolímero de sal de amonio cuaternario de dialiloacrilamida, queratina hidrolizada catiónica, seda hidrolizada catiónica, colágeno hidrolizado catiónico, caseína hidrolizada catiónica, proteína de soja hidrolizada catiónica, un copolímero de vinilpirrolidona catiónica, polivinilpirrolidona, un homopolímero de cloruro de dimetildiacrilamonio, un copolímero de ácido adípico-dimetilaminoh idroxipropildietilentriamina, un copolímero de ácido adípico-epoxipropildietilentriamina y un copolímero de sulfato de acrilamida-?-metacriloiloxietiltrimetil-amoniometilo.
MX2020008925A 2018-02-28 2019-02-27 Composicion oftalmica que comprende dicuafosol y polimero cationico. MX2020008925A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018035578 2018-02-28
PCT/JP2019/007542 WO2019168023A1 (ja) 2018-02-28 2019-02-27 ジクアホソルおよびカチオン性ポリマーを含有する眼科用組成物

Publications (1)

Publication Number Publication Date
MX2020008925A true MX2020008925A (es) 2020-10-01

Family

ID=67806273

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2020008925A MX2020008925A (es) 2018-02-28 2019-02-27 Composicion oftalmica que comprende dicuafosol y polimero cationico.
MX2022014791A MX2022014791A (es) 2018-02-28 2020-08-26 Composicion oftalmica que comprende dicuafosol y polimero cationico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2022014791A MX2022014791A (es) 2018-02-28 2020-08-26 Composicion oftalmica que comprende dicuafosol y polimero cationico.

Country Status (13)

Country Link
US (1) US20210000844A1 (es)
EP (1) EP3760207A4 (es)
JP (4) JP6716800B2 (es)
KR (2) KR20220163519A (es)
CN (2) CN117137866A (es)
BR (1) BR112020017661A2 (es)
CA (1) CA3091700A1 (es)
EA (1) EA202092030A1 (es)
MX (2) MX2020008925A (es)
PH (1) PH12020551313A1 (es)
SG (1) SG11202007977RA (es)
TW (2) TWI781296B (es)
WO (1) WO2019168023A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220163519A (ko) 2018-02-28 2022-12-09 산텐 세이야꾸 가부시키가이샤 디쿠아포솔 및 양이온성 폴리머를 함유하는 안과용 조성물
WO2020175525A1 (ja) * 2019-02-27 2020-09-03 参天製薬株式会社 ジクアホソルまたはその塩、ビニル系高分子およびセルロース系高分子を含有する眼科用組成物
KR20240049646A (ko) * 2019-08-27 2024-04-16 산텐 세이야꾸 가부시키가이샤 디쿠아포솔 또는 그 염 및 폴리비닐피롤리돈을 함유하는 수성 안과용 조성물
JP7230169B2 (ja) * 2020-12-25 2023-02-28 参天製薬株式会社 ジクアホソルまたはその塩、銀塩およびイオン性等張化剤を含有する水性点眼液
CN113712910A (zh) * 2021-08-05 2021-11-30 广州市桐晖药业有限公司 一种滴眼液及其制备方法
KR20230143117A (ko) 2022-04-04 2023-10-11 서울대학교산학협력단 감미 억제용 조성물 및 식품의 감미 억제 방법

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01294620A (ja) 1988-05-19 1989-11-28 Kissei Pharmaceut Co Ltd 水溶液製剤およびその製造方法
US5358706A (en) * 1992-09-30 1994-10-25 Union Carbide Chemicals & Plastics Technology Corporation Muco-adhesive polymers
US5422116A (en) * 1994-02-18 1995-06-06 Ciba-Geigy Corporation Liquid ophthalmic sustained release delivery system
JP3155689B2 (ja) * 1995-08-10 2001-04-16 昭和薬品化工株式会社 消炎点眼剤
US5900407A (en) 1997-02-06 1999-05-04 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with uridine triphosphates and related compounds
PT1012154E (pt) 1997-07-25 2004-08-31 Inspire Pharmaceuticals Inc Sais de di(5'-tetrafosfato de uridina), metodo para a sua preparacao, e suas utilizacoes
KR100832821B1 (ko) * 2000-05-30 2008-05-28 산텐 세이야꾸 가부시키가이샤 각막 상피 신장 촉진제
SG177132A1 (en) * 2005-02-14 2012-01-30 Johnson & Johnson Vision Care A comfortable ophthalmic device and methods of its production
JP4515960B2 (ja) 2005-05-19 2010-08-04 株式会社資生堂 整髪料洗浄剤及びその使用方法
KR100870104B1 (ko) * 2005-11-28 2008-11-26 주식회사 머젠스 안구건조증 치료 및 예방용 조성물
JP5421272B2 (ja) * 2007-10-12 2014-02-19 リゾルヴィクス・ファーマシューティカルズ・インコーポレイテッド 眼病治療のための組成物及び方法
US20110003816A1 (en) * 2008-03-07 2011-01-06 Sun Pharma Advanced Research Company Limited Ophthalmic composition
SG10201508591UA (en) * 2010-12-28 2015-11-27 Santen Pharmaceutical Co Ltd Ophthalmic solution comprising diquafosol, method for producing the same, and method for inhibiting formation of insoluble precipitate
MX353874B (es) * 2012-03-26 2018-02-01 Santen Pharmaceutical Co Ltd Gotas para los ojos que contienen diquafosol.
WO2015169728A1 (en) * 2014-05-07 2015-11-12 Croma-Pharma Gesellschaft M.B.H. Aqueous ophthalmic solution and method for treating dry eye syndrome
CN106456791B (zh) * 2014-06-10 2021-08-10 日本乐敦制药株式会社 眼科用水性组合物
SG11201705138QA (en) * 2014-12-25 2017-07-28 Santen Pharmaceutical Co Ltd Aqueous ophthalmic solution
KR101587385B1 (ko) 2015-07-29 2016-01-21 국제약품공업주식회사 사이클로스포린 함유 무자극성의 안약조성물 및 편리한 제조방법
TW201722419A (zh) * 2015-08-24 2017-07-01 參天製藥股份有限公司 眼科用膜製劑
JP6192130B2 (ja) 2015-12-09 2017-09-06 株式会社大一商会 遊技機
EP3266446B1 (en) * 2016-07-07 2018-11-21 Laboratorios SALVAT, S.A. Ophthalmic composition comprising castor oil and medium chain triglyceride
CN106772747B (zh) * 2016-12-26 2022-10-18 深圳市光科全息技术有限公司 一种光学膜及其制作方法
JP6582029B2 (ja) * 2017-10-03 2019-09-25 株式会社メニコン 眼科用組成液及びその使用方法
KR20220163519A (ko) 2018-02-28 2022-12-09 산텐 세이야꾸 가부시키가이샤 디쿠아포솔 및 양이온성 폴리머를 함유하는 안과용 조성물
CN108853016A (zh) * 2018-09-26 2018-11-23 广州大光制药有限公司 一种地夸磷索钠滴眼液及其制备方法
WO2020175525A1 (ja) * 2019-02-27 2020-09-03 参天製薬株式会社 ジクアホソルまたはその塩、ビニル系高分子およびセルロース系高分子を含有する眼科用組成物

Also Published As

Publication number Publication date
US20210000844A1 (en) 2021-01-07
TWI781296B (zh) 2022-10-21
PH12020551313A1 (en) 2021-09-06
SG11202007977RA (en) 2020-09-29
CA3091700A1 (en) 2019-09-06
KR20220163519A (ko) 2022-12-09
EA202092030A1 (ru) 2020-11-16
MX2022014791A (es) 2023-01-16
BR112020017661A2 (pt) 2020-12-22
EP3760207A4 (en) 2023-10-04
CN111757742A (zh) 2020-10-09
JP6716800B2 (ja) 2020-07-01
KR20200127002A (ko) 2020-11-09
JP7472202B2 (ja) 2024-04-22
KR102472773B1 (ko) 2022-11-30
CN111757742B (zh) 2023-09-26
EP3760207A1 (en) 2021-01-06
TWI833406B (zh) 2024-02-21
TW202306572A (zh) 2023-02-16
CN117137866A (zh) 2023-12-01
WO2019168023A1 (ja) 2019-09-06
JP2022136152A (ja) 2022-09-15
JP2024045506A (ja) 2024-04-02
JP7297718B2 (ja) 2023-06-26
TW202000212A (zh) 2020-01-01
JP2020138980A (ja) 2020-09-03
JPWO2019168023A1 (ja) 2020-05-28

Similar Documents

Publication Publication Date Title
MX2022014791A (es) Composicion oftalmica que comprende dicuafosol y polimero cationico.
BR0114561A (pt) Derivados amida reticulados do acido hialurÈnico e método de produção dos mesmos
MA50746A (fr) Protéines de fusion comprenant des enzymes d'enzymothérapie substitutive
CL2018002825A1 (es) Vacuna contra vrs
WO2021125069A8 (en) Composition comprising hyaluronic acid-based polyion complex particle
EP3721816A3 (en) Improved tissue fixation devices
MXPA02012601A (es) Polimeros radicales cationicos o anfotericos autoadhesivos y su uso en cosmeticos.
RU2014109981A (ru) Способ и устройство для инкапсулирования жесткой вставки в контактную линзу с целью коррекции астигматизма у пациентов
WO2016113550A3 (en) Dressing
BR112018004455A2 (pt) composição formadora de película
SG11201810727SA (en) Elastomer
ATE452611T1 (de) Geräte zur veränderung der relativen krümmung des felds und der positionen von peripheren achsenverschobenen fokalpositionen
BRPI0109443B1 (pt) hidrogel de silicone umectÁvel, lentes oftÁlmicas e mÉtodo de preparaÇço de um hidrogel de silicone.
SG10201705219QA (en) Preparation of N,N-(di)alkylaminoalkyl(meth)acrylamide or N,N-(di)alkylaminoalkyl (meth)acrylate and the quaternary ammonium salts thereof as flocculating aids and gelling agents
EP2996172A3 (en) Biocompatibility of biomedical energization elements
EP3441049A3 (en) Ophthalmic treatment device, system, and method of use
BR112017018491A2 (pt) hidrolisados de proteína à base de leite e composições produzidas a partir dos mesmos
WO2017223261A3 (en) Hydrogels, articles comprising hydrogels, and methods thereof
EP3943076A3 (en) A modified release composition of orlistat and acarbose for the treatment of obesity and related metabolic disorders
BR112015015813A2 (pt) método e aparelho para ajustar a qualidade de vídeo com base em ambiente de rede
MX353032B (es) Sistema y método para programar una lente oftálmica energizada.
WO2004069888A3 (en) Block copolymers
KR20120099621A (ko) 연결 장치
MA49616A (fr) Mutations de protéine d'enveloppe du vih stabilisant la forme trimère
EP3958601A3 (en) Handover method, device, and system