MX2020008925A - Composicion oftalmica que comprende dicuafosol y polimero cationico. - Google Patents

Composicion oftalmica que comprende dicuafosol y polimero cationico.

Info

Publication number
MX2020008925A
MX2020008925A MX2020008925A MX2020008925A MX2020008925A MX 2020008925 A MX2020008925 A MX 2020008925A MX 2020008925 A MX2020008925 A MX 2020008925A MX 2020008925 A MX2020008925 A MX 2020008925A MX 2020008925 A MX2020008925 A MX 2020008925A
Authority
MX
Mexico
Prior art keywords
cationic
copolymers
hydrolyzed
diquafosol
cationic polymer
Prior art date
Application number
MX2020008925A
Other languages
English (en)
Inventor
Asuka Kamimura
Kenichi Endo
Kyohei Takahashi
Hiroyuki Asada
Kenji Morishima
Yusuke Momokawa
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Publication of MX2020008925A publication Critical patent/MX2020008925A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Se proporciona una composición oftálmica que comprende dicuafosol o una sal del mismo y un polímero catiónico, siendo el polímero catiónico al menos uno seleccionado del grupo que consiste de quitosan, un derivado de quitosan, un copolímero de (met)acrilato catiónico, un polímero de silicona catiónica, un copolímero de sal de amonio cuaternario de dialiloacrilamida, queratina hidrolizada catiónica, seda hidrolizada catiónica, colágeno hidrolizado catiónico, caseína hidrolizada catiónica, proteína de soja hidrolizada catiónica, un copolímero de vinilpirrolidona catiónica, polivinilpirrolidona, un homopolímero de cloruro de dimetildiacrilamonio, un copolímero de ácido adípico-dimetilaminoh idroxipropildietilentriamina, un copolímero de ácido adípico-epoxipropildietilentriamina y un copolímero de sulfato de acrilamida-?-metacriloiloxietiltrimetil-amoniometilo.
MX2020008925A 2018-02-28 2019-02-27 Composicion oftalmica que comprende dicuafosol y polimero cationico. MX2020008925A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018035578 2018-02-28
PCT/JP2019/007542 WO2019168023A1 (ja) 2018-02-28 2019-02-27 ジクアホソルおよびカチオン性ポリマーを含有する眼科用組成物

Publications (1)

Publication Number Publication Date
MX2020008925A true MX2020008925A (es) 2020-10-01

Family

ID=67806273

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2020008925A MX2020008925A (es) 2018-02-28 2019-02-27 Composicion oftalmica que comprende dicuafosol y polimero cationico.
MX2022014791A MX2022014791A (es) 2018-02-28 2020-08-26 Composicion oftalmica que comprende dicuafosol y polimero cationico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2022014791A MX2022014791A (es) 2018-02-28 2020-08-26 Composicion oftalmica que comprende dicuafosol y polimero cationico.

Country Status (13)

Country Link
US (1) US20210000844A1 (es)
EP (1) EP3760207A4 (es)
JP (4) JP6716800B2 (es)
KR (2) KR102472773B1 (es)
CN (2) CN111757742B (es)
BR (1) BR112020017661A2 (es)
CA (1) CA3091700A1 (es)
EA (1) EA202092030A1 (es)
MX (2) MX2020008925A (es)
PH (1) PH12020551313A1 (es)
SG (1) SG11202007977RA (es)
TW (2) TWI833406B (es)
WO (1) WO2019168023A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI833406B (zh) 2018-02-28 2024-02-21 日商參天製藥股份有限公司 含有迪夸弗索（Ｄｉｑｕａｆｏｓｏｌ）及陽離子性聚合物之眼科用組合物
CN113518646B (zh) * 2019-02-27 2023-12-12 参天制药株式会社 含有地夸磷索或其盐，乙烯基系高分子及纤维素系高分子的眼科用组合物
TW202122094A (zh) * 2019-08-27 2021-06-16 日商參天製藥股份有限公司 含有迪夸弗索(diquafosol)或其鹽、及聚乙烯吡咯烷酮之水性眼科用組合物
JP7230169B2 (ja) * 2020-12-25 2023-02-28 参天製薬株式会社 ジクアホソルまたはその塩、銀塩およびイオン性等張化剤を含有する水性点眼液
CN113712910A (zh) * 2021-08-05 2021-11-30 广州市桐晖药业有限公司 一种滴眼液及其制备方法
KR20230143117A (ko) 2022-04-04 2023-10-11 서울대학교산학협력단 감미 억제용 조성물 및 식품의 감미 억제 방법

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TWI833406B (zh) 2018-02-28 2024-02-21 日商參天製藥股份有限公司 含有迪夸弗索（Ｄｉｑｕａｆｏｓｏｌ）及陽離子性聚合物之眼科用組合物
CN108853016A (zh) * 2018-09-26 2018-11-23 广州大光制药有限公司 一种地夸磷索钠滴眼液及其制备方法
CN113518646B (zh) * 2019-02-27 2023-12-12 参天制药株式会社 含有地夸磷索或其盐，乙烯基系高分子及纤维素系高分子的眼科用组合物

Also Published As

Publication number Publication date
MX2022014791A (es) 2023-01-16
TWI833406B (zh) 2024-02-21
US20210000844A1 (en) 2021-01-07
TWI781296B (zh) 2022-10-21
PH12020551313A1 (en) 2021-09-06
JP7297718B2 (ja) 2023-06-26
JP2020138980A (ja) 2020-09-03
BR112020017661A2 (pt) 2020-12-22
KR102472773B1 (ko) 2022-11-30
CN111757742B (zh) 2023-09-26
JP7472202B2 (ja) 2024-04-22
KR20200127002A (ko) 2020-11-09
JPWO2019168023A1 (ja) 2020-05-28
SG11202007977RA (en) 2020-09-29
EP3760207A1 (en) 2021-01-06
TW202000212A (zh) 2020-01-01
EA202092030A1 (ru) 2020-11-16
EP3760207A4 (en) 2023-10-04
KR20220163519A (ko) 2022-12-09
JP2022136152A (ja) 2022-09-15
CA3091700A1 (en) 2019-09-06
JP6716800B2 (ja) 2020-07-01
TW202306572A (zh) 2023-02-16
CN111757742A (zh) 2020-10-09
JP2024045506A (ja) 2024-04-02
CN117137866A (zh) 2023-12-01
WO2019168023A1 (ja) 2019-09-06

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