MX2019008016A - Secuenciacion gradual por terminadores reversibles no etiquetados o nucleotidos naturales. - Google Patents
Secuenciacion gradual por terminadores reversibles no etiquetados o nucleotidos naturales.Info
- Publication number
- MX2019008016A MX2019008016A MX2019008016A MX2019008016A MX2019008016A MX 2019008016 A MX2019008016 A MX 2019008016A MX 2019008016 A MX2019008016 A MX 2019008016A MX 2019008016 A MX2019008016 A MX 2019008016A MX 2019008016 A MX2019008016 A MX 2019008016A
- Authority
- MX
- Mexico
- Prior art keywords
- reversible terminators
- natural nucleotides
- sequencing
- labeled reversible
- stepwise sequencing
- Prior art date
Links
- 230000002441 reversible effect Effects 0.000 title abstract 3
- 238000012163 sequencing technique Methods 0.000 title abstract 3
- 239000002773 nucleotide Substances 0.000 title 1
- 125000003729 nucleotide group Chemical group 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000010348 incorporation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Abstract
La invención proporciona composiciones y métodos para secuenciar ácidos nucleicos y otras aplicaciones. En secuenciación por síntesis, se incorporan terminadores reversibles no etiquetados por una polimerasa en cada ciclo, entonces se etiquetan después de la incorporación al unir al terminador reversible un anticuerpo directamente o indirectamente etiquetado u otro reactivo de afinidad.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762442263P | 2017-01-04 | 2017-01-04 | |
US201762490511P | 2017-04-26 | 2017-04-26 | |
PCT/US2018/012425 WO2018129214A1 (en) | 2017-01-04 | 2018-01-04 | Stepwise sequencing by non-labeled reversible terminators or natural nucleotides |
Publications (1)
Publication Number | Publication Date |
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MX2019008016A true MX2019008016A (es) | 2019-10-15 |
Family
ID=62791177
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019008016A MX2019008016A (es) | 2017-01-04 | 2018-01-04 | Secuenciacion gradual por terminadores reversibles no etiquetados o nucleotidos naturales. |
Country Status (17)
Country | Link |
---|---|
US (3) | US10851410B2 (es) |
EP (2) | EP3565905B1 (es) |
JP (2) | JP2020508037A (es) |
KR (1) | KR102349259B1 (es) |
CN (1) | CN110418847A (es) |
AU (2) | AU2018205472B2 (es) |
BR (1) | BR112019013715B1 (es) |
CA (1) | CA3048486A1 (es) |
DK (1) | DK3565905T3 (es) |
ES (1) | ES2924223T3 (es) |
HU (1) | HUE059673T2 (es) |
IL (1) | IL267836B2 (es) |
MX (1) | MX2019008016A (es) |
PL (1) | PL3565905T3 (es) |
PT (1) | PT3565905T (es) |
RS (1) | RS63419B1 (es) |
WO (1) | WO2018129214A1 (es) |
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EP3565905B1 (en) | 2017-01-04 | 2022-05-25 | MGI Tech Co., Ltd. | Nucleic acid sequencing using affinity reagents |
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2018
- 2018-01-04 EP EP18736171.2A patent/EP3565905B1/en active Active
- 2018-01-04 DK DK18736171.2T patent/DK3565905T3/da active
- 2018-01-04 KR KR1020197022620A patent/KR102349259B1/ko active IP Right Review Request
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2020
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KR102349259B9 (ko) | 2022-07-20 |
IL267836A (en) | 2019-09-26 |
US20210254150A1 (en) | 2021-08-19 |
CA3048486A1 (en) | 2018-07-12 |
AU2023201547A1 (en) | 2023-04-13 |
JP2022046677A (ja) | 2022-03-23 |
CN110418847A (zh) | 2019-11-05 |
US10851410B2 (en) | 2020-12-01 |
EP4112741A1 (en) | 2023-01-04 |
HUE059673T2 (hu) | 2022-12-28 |
ES2924223T3 (es) | 2022-10-05 |
PT3565905T (pt) | 2022-08-02 |
PL3565905T3 (pl) | 2022-09-26 |
WO2018129214A1 (en) | 2018-07-12 |
AU2018205472B2 (en) | 2022-12-15 |
KR102349259B1 (ko) | 2022-01-07 |
EP3565905A1 (en) | 2019-11-13 |
JP7025595B1 (ja) | 2022-02-24 |
BR112019013715A2 (pt) | 2020-03-03 |
KR20190141120A (ko) | 2019-12-23 |
IL267836B1 (en) | 2023-05-01 |
JP2020508037A (ja) | 2020-03-19 |
US20180223358A1 (en) | 2018-08-09 |
US11788138B2 (en) | 2023-10-17 |
IL267836B2 (en) | 2023-09-01 |
US20240117425A1 (en) | 2024-04-11 |
DK3565905T3 (da) | 2022-07-25 |
AU2018205472A1 (en) | 2019-07-25 |
EP3565905B1 (en) | 2022-05-25 |
EP3565905A4 (en) | 2020-11-04 |
BR112019013715B1 (pt) | 2021-08-24 |
RS63419B1 (sr) | 2022-08-31 |
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