ATE542915T1 - Cst-ii-modifzierungen für erhöhte proteinexpression - Google Patents

Cst-ii-modifzierungen für erhöhte proteinexpression

Info

Publication number
ATE542915T1
ATE542915T1 AT07762625T AT07762625T ATE542915T1 AT E542915 T1 ATE542915 T1 AT E542915T1 AT 07762625 T AT07762625 T AT 07762625T AT 07762625 T AT07762625 T AT 07762625T AT E542915 T1 ATE542915 T1 AT E542915T1
Authority
AT
Austria
Prior art keywords
cst
modifications
protein expression
increased protein
sialyltransferase proteins
Prior art date
Application number
AT07762625T
Other languages
English (en)
Inventor
Karl Johnson
Aliakbar Mobasseri
Xiaomei Bai
Kyle Kinealy
Original Assignee
Biogenerix Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogenerix Ag filed Critical Biogenerix Ag
Application granted granted Critical
Publication of ATE542915T1 publication Critical patent/ATE542915T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT07762625T 2006-02-01 2007-02-01 Cst-ii-modifzierungen für erhöhte proteinexpression ATE542915T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US76462506P 2006-02-01 2006-02-01
US76449906P 2006-02-01 2006-02-01
US77408806P 2006-02-15 2006-02-15
US77394106P 2006-02-15 2006-02-15
PCT/US2007/002878 WO2007089923A2 (en) 2006-02-01 2007-02-01 Modifications of cst-ii for increased protein expression

Publications (1)

Publication Number Publication Date
ATE542915T1 true ATE542915T1 (de) 2012-02-15

Family

ID=38328065

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07762625T ATE542915T1 (de) 2006-02-01 2007-02-01 Cst-ii-modifzierungen für erhöhte proteinexpression

Country Status (6)

Country Link
US (1) US7968310B2 (de)
EP (1) EP1984013B1 (de)
AT (1) ATE542915T1 (de)
CA (1) CA2638910A1 (de)
ES (1) ES2381504T3 (de)
WO (1) WO2007089923A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101750458B (zh) * 2009-11-05 2013-04-17 香港科技大学 一种检测人体中毒品残留的方法
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US20210087599A1 (en) * 2017-07-26 2021-03-25 Jennewein Biotechnologie Gmbh Sialyltransferases and their use in producing sialylated oligosaccharides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096529A (en) 1996-06-10 2000-08-01 National Research Council Of Canada Recombinant α-2,3-sialyltransferases and their uses
US6689604B1 (en) * 1998-03-20 2004-02-10 National Research Council Of Canada Lipopolysaccharide α-2,3 sialyltransferase of Campylobacter jejuni and its uses
US6699705B2 (en) * 1999-02-01 2004-03-02 National Research Council Of Canada Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics
US6503744B1 (en) * 1999-02-01 2003-01-07 National Research Council Of Canada Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics
CA2547140A1 (en) 2003-11-24 2005-06-09 Neose Technologies, Inc. Glycopegylated erythropoietin
CA2579368A1 (en) 2004-09-17 2006-03-23 National Research Council Of Canada Sialyltransferases comprising conserved sequence motifs

Also Published As

Publication number Publication date
EP1984013B1 (de) 2012-01-25
ES2381504T3 (es) 2012-05-28
WO2007089923A3 (en) 2008-10-09
CA2638910A1 (en) 2007-08-09
US7968310B2 (en) 2011-06-28
EP1984013A4 (de) 2010-01-27
WO2007089923A2 (en) 2007-08-09
US20090186377A1 (en) 2009-07-23
EP1984013A2 (de) 2008-10-29

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