PL3565905T3 - Sekwencjonowanie kwasów nukleinowych z zastosowaniem odczynników powinowactwa - Google Patents
Sekwencjonowanie kwasów nukleinowych z zastosowaniem odczynników powinowactwaInfo
- Publication number
- PL3565905T3 PL3565905T3 PL18736171.2T PL18736171T PL3565905T3 PL 3565905 T3 PL3565905 T3 PL 3565905T3 PL 18736171 T PL18736171 T PL 18736171T PL 3565905 T3 PL3565905 T3 PL 3565905T3
- Authority
- PL
- Poland
- Prior art keywords
- nucleic acid
- acid sequencing
- affinity reagents
- affinity
- reagents
- Prior art date
Links
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 238000012163 sequencing technique Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Saccharide Compounds (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762442263P | 2017-01-04 | 2017-01-04 | |
| US201762490511P | 2017-04-26 | 2017-04-26 | |
| PCT/US2018/012425 WO2018129214A1 (en) | 2017-01-04 | 2018-01-04 | Stepwise sequencing by non-labeled reversible terminators or natural nucleotides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3565905T3 true PL3565905T3 (pl) | 2022-09-26 |
Family
ID=62791177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18736171.2T PL3565905T3 (pl) | 2017-01-04 | 2018-01-04 | Sekwencjonowanie kwasów nukleinowych z zastosowaniem odczynników powinowactwa |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US10851410B2 (pl) |
| EP (2) | EP4112741A1 (pl) |
| JP (2) | JP2020508037A (pl) |
| KR (1) | KR102349259B1 (pl) |
| CN (1) | CN110418847A (pl) |
| AU (2) | AU2018205472B2 (pl) |
| BR (1) | BR112019013715B1 (pl) |
| CA (1) | CA3048486A1 (pl) |
| DK (1) | DK3565905T3 (pl) |
| ES (1) | ES2924223T3 (pl) |
| HU (1) | HUE059673T2 (pl) |
| IL (1) | IL267836B2 (pl) |
| MX (2) | MX2019008016A (pl) |
| PL (1) | PL3565905T3 (pl) |
| PT (1) | PT3565905T (pl) |
| RS (1) | RS63419B1 (pl) |
| WO (1) | WO2018129214A1 (pl) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018129214A1 (en) | 2017-01-04 | 2018-07-12 | Complete Genomics, Inc. | Stepwise sequencing by non-labeled reversible terminators or natural nucleotides |
| WO2019067635A1 (en) | 2017-09-27 | 2019-04-04 | Ultima Genomics, Inc. | METHODS AND SYSTEMS FOR NUCLEIC ACID SEQUENCING |
| EP3878968A4 (en) * | 2018-11-07 | 2022-08-17 | EGI Tech (Shen Zhen) Co., Limited | POLYNUCLEOTIDE SEQUENCING METHOD |
| EP3877548A4 (en) * | 2018-11-09 | 2022-10-05 | MGI Tech Co., Ltd. | MASSIVE PARALLEL SEQUENCING USING UNLABELED NUCLEOTIDES |
| CN112805390B (zh) * | 2018-12-05 | 2024-04-05 | 青岛华大智造科技有限责任公司 | 滚环扩增方法、测序文库制备方法及制得的dna纳米球 |
| EP3702474A1 (en) * | 2019-02-26 | 2020-09-02 | QIAGEN GmbH | Sequencing method and kit |
| BR112021022809A2 (pt) * | 2019-05-15 | 2022-01-25 | Egi Tech Shen Zhen Co Ltd | Método de sequenciamento de canal único baseado em autoluminescência |
| JP2023506103A (ja) * | 2019-12-16 | 2023-02-15 | イルミナ インコーポレイテッド | キット及びフローセル |
| JP7500727B2 (ja) * | 2019-12-18 | 2024-06-17 | エフ． ホフマン－ラ ロシュ アーゲー | 連続的な標識スキームを使用した合成による配列決定方法 |
| US20210189483A1 (en) | 2019-12-23 | 2021-06-24 | Mgi Tech Co. Ltd. | Controlled strand-displacement for paired end sequencing |
| US12110548B2 (en) | 2020-02-03 | 2024-10-08 | 10X Genomics, Inc. | Bi-directional in situ analysis |
| WO2021185320A1 (en) | 2020-03-18 | 2021-09-23 | Mgi Tech Co., Ltd. | Restoring phase in massively parallel sequencing |
| CN113795595B (zh) | 2020-04-20 | 2023-02-28 | 深圳华大智造科技股份有限公司 | Dna成像缓冲液中的dna保护试剂 |
| EP4143333A1 (en) | 2020-04-30 | 2023-03-08 | Dimensiongen | Devices and methods for macromolecular manipulation |
| US11981964B2 (en) | 2020-07-28 | 2024-05-14 | Illumina Cambridge Limited | Substituted coumarin dyes and uses as fluorescent labels |
| US20230375556A1 (en) * | 2020-10-12 | 2023-11-23 | Mgi Tech Co., Ltd. | Protein detection and tracking using nucleoside tags |
| GB2599729A (en) * | 2020-10-12 | 2022-04-13 | Sumitomo Chemical Co | Method comprising light emitting marker |
| CN116507736A (zh) | 2020-10-21 | 2023-07-28 | 深圳华大生命科学研究院 | 修饰的核苷或核苷酸 |
| US20220195196A1 (en) | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Alkylpyridinium coumarin dyes and uses in sequencing applications |
| US20220195516A1 (en) | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Methods, systems and compositions for nucleic acid sequencing |
| US20220195517A1 (en) | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Long stokes shift chromenoquinoline dyes and uses in sequencing applications |
| US20220195518A1 (en) * | 2020-12-22 | 2022-06-23 | Illumina Cambridge Limited | Methods and compositions for nucleic acid sequencing |
| US20240158839A1 (en) | 2021-03-15 | 2024-05-16 | President And Fellows Of Harvard College | Methods for in situ sequencing |
| CN115197291A (zh) | 2021-04-01 | 2022-10-18 | 深圳华大生命科学研究院 | 用于测序的核苷酸类似物 |
| AU2022269804A1 (en) | 2021-05-05 | 2023-11-02 | Illumina Cambridge Limited | Fluorescent dyes containing bis-boron fused heterocycles and uses in sequencing |
| CN113372402A (zh) * | 2021-06-15 | 2021-09-10 | 中国人民解放军军事科学院军事医学研究院 | 3’-o-可逆封闭的核苷酸及其在无模板酶促核酸合成中的应用 |
| WO2023114896A1 (en) | 2021-12-16 | 2023-06-22 | Illumina Cambridge Limited | Methods for metal directed cleavage of surface-bound polynucleotides |
| CN117940577A (zh) | 2021-12-20 | 2024-04-26 | 因美纳有限公司 | 用于化学裂解表面结合的多核苷酸的高碘酸盐组合物和方法 |
| AU2022421156A1 (en) | 2021-12-20 | 2024-01-18 | Illumina, Inc. | Periodate compositions and methods for chemical cleavage of surface-bound polynucleotides |
| US20230314322A1 (en) | 2022-03-29 | 2023-10-05 | Illumina, Inc. | Systems and methods of sequencing polynucleotides |
| US20230313294A1 (en) | 2022-03-30 | 2023-10-05 | Illumina Cambridge Limited | Methods for chemical cleavage of surface-bound polynucleotides |
| AU2023244351A1 (en) * | 2022-03-31 | 2024-01-18 | Illumina, Inc. | Nucleosides and nucleotides with 3' vinyl blocking group useful in sequencing by synthesis |
| US20230357845A1 (en) | 2022-03-31 | 2023-11-09 | Illumina, Inc. | Compositions and methods for improving sequencing signals |
| US20230416279A1 (en) | 2022-06-28 | 2023-12-28 | Illumina Cambridge Limited | Fluorescent dyes containing fused tetracyclic bis-boron heterocycle and uses in sequencing |
| WO2024068889A2 (en) | 2022-09-30 | 2024-04-04 | Illumina, Inc. | Compositions and methods for reducing photo damage during sequencing |
| WO2024123866A1 (en) | 2022-12-09 | 2024-06-13 | Illumina, Inc. | Nucleosides and nucleotides with 3´ blocking groups and cleavable linkers |
| AU2023409138A1 (en) | 2022-12-22 | 2024-10-03 | Illumina, Inc. | Transition-metal catalyst compositions and methods for sequencing by synthesis |
| WO2024137774A1 (en) | 2022-12-22 | 2024-06-27 | Illumina, Inc. | Palladium catalyst compositions and methods for sequencing by synthesis |
| US20240271206A1 (en) | 2022-12-27 | 2024-08-15 | Illumina, Inc. | Methods of sequencing using 3' allyl blocked nucleotides |
| US20240327910A1 (en) | 2023-03-29 | 2024-10-03 | Illumina, Inc. | Naphthalimide dyes and uses in nucleic acid sequencing |
| US20240327909A1 (en) | 2023-03-30 | 2024-10-03 | Illumina, Inc. | Compositions and methods for nucleic acid sequencing |
| CN116536399A (zh) * | 2023-07-07 | 2023-08-04 | 之江实验室 | 一种基于微珠测序的基因芯片编解码方法及基因芯片 |
Family Cites Families (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2713102A (en) | 1952-06-25 | 1955-07-12 | Railroad Accessories Corp | Test terminal |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4351760A (en) | 1979-09-07 | 1982-09-28 | Syva Company | Novel alkyl substituted fluorescent compounds and polyamino acid conjugates |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| CA2020958C (en) | 1989-07-11 | 2005-01-11 | Daniel L. Kacian | Nucleic acid sequence amplification methods |
| US5053336A (en) * | 1989-07-17 | 1991-10-01 | Regents Of The University Of California | Monoclonal antibodies for the separate detection of halodeoxyuridines and method for their use |
| US5188934A (en) | 1989-11-14 | 1993-02-23 | Applied Biosystems, Inc. | 4,7-dichlorofluorescein dyes as molecular probes |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| US6401267B1 (en) | 1993-09-27 | 2002-06-11 | Radoje Drmanac | Methods and compositions for efficient nucleic acid sequencing |
| US6232465B1 (en) | 1994-09-02 | 2001-05-15 | Andrew C. Hiatt | Compositions for enzyme catalyzed template-independent creation of phosphodiester bonds using protected nucleotides |
| US5854033A (en) | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
| AU726501B2 (en) | 1996-06-04 | 2000-11-09 | University Of Utah Research Foundation | Monitoring hybridization during PCR |
| GB9620209D0 (en) | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
| GB9626815D0 (en) | 1996-12-23 | 1997-02-12 | Cemu Bioteknik Ab | Method of sequencing DNA |
| US6969488B2 (en) | 1998-05-22 | 2005-11-29 | Solexa, Inc. | System and apparatus for sequential processing of analytes |
| EP1028970A1 (en) | 1997-10-10 | 2000-08-23 | President And Fellows Of Harvard College | Replica amplification of nucleic acid arrays |
| US6743605B1 (en) | 1998-06-24 | 2004-06-01 | Enzo Life Sciences, Inc. | Linear amplification of specific nucleic acid sequences |
| US6787308B2 (en) | 1998-07-30 | 2004-09-07 | Solexa Ltd. | Arrayed biomolecules and their use in sequencing |
| US20030022207A1 (en) | 1998-10-16 | 2003-01-30 | Solexa, Ltd. | Arrayed polynucleotides and their use in genome analysis |
| AU770993B2 (en) | 1998-09-15 | 2004-03-11 | Yale University | Molecular cloning using rolling circle amplification |
| AR021833A1 (es) | 1998-09-30 | 2002-08-07 | Applied Research Systems | Metodos de amplificacion y secuenciacion de acido nucleico |
| GB9901475D0 (en) | 1999-01-22 | 1999-03-17 | Pyrosequencing Ab | A method of DNA sequencing |
| US20050181440A1 (en) | 1999-04-20 | 2005-08-18 | Illumina, Inc. | Nucleic acid sequencing using microsphere arrays |
| ATE338273T1 (de) | 1999-05-20 | 2006-09-15 | Illumina Inc | Vorrichtung zur halterung und präsentation von mindestens einer mikrokugelmatrix zu lösungen und/oder zu optischen abbildungssystemen |
| US6544732B1 (en) | 1999-05-20 | 2003-04-08 | Illumina, Inc. | Encoding and decoding of array sensors utilizing nanocrystals |
| US6818395B1 (en) | 1999-06-28 | 2004-11-16 | California Institute Of Technology | Methods and apparatus for analyzing polynucleotide sequences |
| US7244559B2 (en) | 1999-09-16 | 2007-07-17 | 454 Life Sciences Corporation | Method of sequencing a nucleic acid |
| US6274320B1 (en) | 1999-09-16 | 2001-08-14 | Curagen Corporation | Method of sequencing a nucleic acid |
| AU7537200A (en) | 1999-09-29 | 2001-04-30 | Solexa Ltd. | Polynucleotide sequencing |
| JP2001245698A (ja) * | 1999-11-22 | 2001-09-11 | Xiao Bing Wang | 核酸検出法 |
| GB0002389D0 (en) | 2000-02-02 | 2000-03-22 | Solexa Ltd | Molecular arrays |
| JP3852555B2 (ja) | 2000-09-01 | 2006-11-29 | 三菱電機株式会社 | 熱制御装置、宇宙機および熱制御方法 |
| WO2002027029A2 (en) | 2000-09-27 | 2002-04-04 | Lynx Therapeutics, Inc. | Method for determining relative abundance of nucleic acid sequences |
| ATE356222T1 (de) | 2000-10-06 | 2007-03-15 | Univ Columbia | Massives parallelverfahren zur dekodierung von dna und rna |
| GB0105831D0 (en) * | 2001-03-09 | 2001-04-25 | Toumaz Technology Ltd | Method for dna sequencing utilising enzyme linked field effect transistors |
| US20030124560A1 (en) * | 2001-06-14 | 2003-07-03 | Yoshihiko Makino | Method for analyzing a target nucleic acid fragment and a kit for analyzing a target nucleic acid fragment |
| AU2002303065B2 (en) * | 2001-06-14 | 2007-09-06 | Cavidi Tech Ab | A method for measuring DNA polymerization and applications of the method |
| JP4500540B2 (ja) * | 2001-06-29 | 2010-07-14 | ヴェリ‐キュー，インコーポレイテッド | 化学的に合成された核酸の純度を決定し、かつ化学的に合成された核酸を精製するための方法および組成物 |
| FR2836995B1 (fr) * | 2002-03-05 | 2006-09-22 | Centre Nat Rech Scient | Utilisation de derives de nucleosides comportant un groupement citrate pour la production d'anticorps ayant une affinite pour des nucleosides triphosphorylees et leurs applications |
| US7595883B1 (en) | 2002-09-16 | 2009-09-29 | The Board Of Trustees Of The Leland Stanford Junior University | Biological analysis arrangement and approach therefor |
| DE602004036672C5 (de) * | 2003-01-29 | 2012-11-29 | 454 Life Sciences Corporation | Nukleinsäureamplifikation auf Basis von Kügelchenemulsion |
| DE602004021235D1 (de) * | 2003-02-21 | 2009-07-09 | Geneform Technologies Ltd | Verfahren, kits und reagenzien zur nukleinsäuresequenzierung |
| CA2897376A1 (en) | 2003-02-26 | 2004-09-10 | Radoje T. Drmanac | Modular system and probes for dna analysis |
| GB0321306D0 (en) | 2003-09-11 | 2003-10-15 | Solexa Ltd | Modified polymerases for improved incorporation of nucleotide analogues |
| CA2557841A1 (en) | 2004-02-27 | 2005-09-09 | President And Fellows Of Harvard College | Polony fluorescent in situ sequencing beads |
| US20060024711A1 (en) | 2004-07-02 | 2006-02-02 | Helicos Biosciences Corporation | Methods for nucleic acid amplification and sequence determination |
| WO2006073504A2 (en) | 2004-08-04 | 2006-07-13 | President And Fellows Of Harvard College | Wobble sequencing |
| JP4990886B2 (ja) | 2005-05-10 | 2012-08-01 | ソレックサ リミテッド | 改良ポリメラーゼ |
| EP1904529B1 (en) | 2005-06-10 | 2010-08-11 | Medical Research Council | Use of stefin a as a scaffold protein |
| CA2611671C (en) | 2005-06-15 | 2013-10-08 | Callida Genomics, Inc. | Single molecule arrays for genetic and chemical analysis |
| US7960104B2 (en) | 2005-10-07 | 2011-06-14 | Callida Genomics, Inc. | Self-assembled single molecule arrays and uses thereof |
| WO2007120208A2 (en) | 2005-11-14 | 2007-10-25 | President And Fellows Of Harvard College | Nanogrid rolling circle dna sequencing |
| EP1994180A4 (en) | 2006-02-24 | 2009-11-25 | Callida Genomics Inc | GENOME SEQUENCING ON DNA ARRAYS WITH HIGH THROUGHPUT |
| SG170028A1 (en) | 2006-02-24 | 2011-04-29 | Callida Genomics Inc | High throughput genome sequencing on dna arrays |
| WO2008045575A2 (en) | 2006-10-13 | 2008-04-17 | J. Craig Venter Institute, Inc. | Sequencing method |
| US7910354B2 (en) | 2006-10-27 | 2011-03-22 | Complete Genomics, Inc. | Efficient arrays of amplified polynucleotides |
| US8262900B2 (en) | 2006-12-14 | 2012-09-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| US8349167B2 (en) | 2006-12-14 | 2013-01-08 | Life Technologies Corporation | Methods and apparatus for detecting molecular interactions using FET arrays |
| EP2653861B1 (en) | 2006-12-14 | 2014-08-13 | Life Technologies Corporation | Method for sequencing a nucleic acid using large-scale FET arrays |
| US8518640B2 (en) | 2007-10-29 | 2013-08-27 | Complete Genomics, Inc. | Nucleic acid sequencing and process |
| US7897344B2 (en) | 2007-11-06 | 2011-03-01 | Complete Genomics, Inc. | Methods and oligonucleotide designs for insertion of multiple adaptors into library constructs |
| US7901890B2 (en) | 2007-11-05 | 2011-03-08 | Complete Genomics, Inc. | Methods and oligonucleotide designs for insertion of multiple adaptors employing selective methylation |
| US8415099B2 (en) | 2007-11-05 | 2013-04-09 | Complete Genomics, Inc. | Efficient base determination in sequencing reactions |
| WO2009073629A2 (en) | 2007-11-29 | 2009-06-11 | Complete Genomics, Inc. | Efficient shotgun sequencing methods |
| WO2009097368A2 (en) | 2008-01-28 | 2009-08-06 | Complete Genomics, Inc. | Methods and compositions for efficient base calling in sequencing reactions |
| WO2009120374A2 (en) | 2008-03-28 | 2009-10-01 | Pacific Biosciences Of California, Inc. | Methods and compositions for nucleic acid sample preparation |
| GB0807065D0 (en) | 2008-04-18 | 2008-05-21 | Univ Leeds | Novel scaffolds |
| EP2297344B1 (en) * | 2008-05-16 | 2018-03-14 | Life Technologies Corporation | Dual labeling methods for measuring cellular proliferation |
| US20100137143A1 (en) | 2008-10-22 | 2010-06-03 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
| WO2010075188A2 (en) | 2008-12-23 | 2010-07-01 | Illumina Inc. | Multibase delivery for long reads in sequencing by synthesis protocols |
| US20140228223A1 (en) | 2010-05-10 | 2014-08-14 | Andreas Gnirke | High throughput paired-end sequencing of large-insert clone libraries |
| US9005565B2 (en) | 2010-06-24 | 2015-04-14 | Hamid-Reza Jahangiri-Famenini | Method and apparatus for forming graphene |
| US9051263B2 (en) | 2010-08-25 | 2015-06-09 | Pacific Biosciences Of California, Inc. | Functionalized cyanine dyes (PEG) |
| US9453258B2 (en) * | 2011-09-23 | 2016-09-27 | Illumina, Inc. | Methods and compositions for nucleic acid sequencing |
| US8671811B2 (en) | 2011-09-30 | 2014-03-18 | Robert Bosch Gmbh | Pivoting saw system |
| GB201301178D0 (en) * | 2013-01-23 | 2013-03-06 | Dynamic Biosensors Gmbh | Method for sequencing a template nucleic acid immobilized on a substrate |
| US9650406B2 (en) * | 2013-02-28 | 2017-05-16 | Centrillion Technology Holdings Corporation | Reversible terminator molecules and methods of their use |
| US9944924B2 (en) | 2014-01-16 | 2018-04-17 | Illumina, Inc. | Polynucleotide modification on solid support |
| CN107074904B (zh) | 2014-10-23 | 2022-12-23 | 深圳华大智造科技股份有限公司 | 信号约束测序(scs)和用于信号约束测序的核苷酸类似物 |
| CN104448001A (zh) | 2014-11-14 | 2015-03-25 | 杭州博谱医药科技有限公司 | 抗5-甲基-胞嘧啶单克隆抗体及其应用 |
| WO2016133764A1 (en) | 2015-02-17 | 2016-08-25 | Complete Genomics, Inc. | Dna sequencing using controlled strand displacement |
| US20170240961A1 (en) | 2016-02-23 | 2017-08-24 | Complete Genomics, Inc. | Affinity tag labeled nucleosides and uses |
| WO2017185026A1 (en) * | 2016-04-22 | 2017-10-26 | Complete Genomics, Inc. | Reversibly blocked nucleoside analogues and their use |
| JP6828140B2 (ja) | 2016-08-15 | 2021-02-10 | オムニオム インコーポレイテッドＯｍｎｉｏｍｅ， Ｉｎｃ． | 核酸をシーケンシングするための方法及びシステム |
| WO2018129214A1 (en) | 2017-01-04 | 2018-07-12 | Complete Genomics, Inc. | Stepwise sequencing by non-labeled reversible terminators or natural nucleotides |
-
2018
- 2018-01-04 WO PCT/US2018/012425 patent/WO2018129214A1/en unknown
- 2018-01-04 KR KR1020197022620A patent/KR102349259B1/ko active IP Right Review Request
- 2018-01-04 CA CA3048486A patent/CA3048486A1/en active Pending
- 2018-01-04 EP EP22174722.3A patent/EP4112741A1/en active Pending
- 2018-01-04 CN CN201880005910.5A patent/CN110418847A/zh active Pending
- 2018-01-04 PT PT187361712T patent/PT3565905T/pt unknown
- 2018-01-04 MX MX2019008016A patent/MX2019008016A/es unknown
- 2018-01-04 PL PL18736171.2T patent/PL3565905T3/pl unknown
- 2018-01-04 BR BR112019013715-7A patent/BR112019013715B1/pt active IP Right Grant
- 2018-01-04 JP JP2019536551A patent/JP2020508037A/ja not_active Withdrawn
- 2018-01-04 EP EP18736171.2A patent/EP3565905B1/en active Active
- 2018-01-04 HU HUE18736171A patent/HUE059673T2/hu unknown
- 2018-01-04 IL IL267836A patent/IL267836B2/en unknown
- 2018-01-04 US US15/862,566 patent/US10851410B2/en active Active
- 2018-01-04 AU AU2018205472A patent/AU2018205472B2/en active Active
- 2018-01-04 RS RS20220695A patent/RS63419B1/sr unknown
- 2018-01-04 DK DK18736171.2T patent/DK3565905T3/da active
- 2018-01-04 ES ES18736171T patent/ES2924223T3/es active Active
-
2019
- 2019-07-03 MX MX2024006412A patent/MX2024006412A/es unknown
-
2020
- 2020-10-29 US US17/084,482 patent/US11788138B2/en active Active
-
2021
- 2021-12-27 JP JP2021212172A patent/JP7025595B1/ja active Active
-
2023
- 2023-03-14 AU AU2023201547A patent/AU2023201547A1/en active Pending
- 2023-09-07 US US18/462,652 patent/US20240117425A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RS63419B1 (sr) | Sekvenciranje nukleinske kiseline upotrebom afinitetnih reagenasa | |
| EP3472359A4 (en) | NUCLEIC ACID SEQUENCING | |
| SG11201911430PA (en) | Novel nucleic acid molecules | |
| HK1250757A1 (zh) | 來自單細胞的核酸序列分析 | |
| GB201704402D0 (en) | Single cell DNA sequencing | |
| HK1250051A1 (zh) | 核酸測序方法和系統 | |
| EP3545076A4 (en) | NUCLEIC ACID SEQUENCING DEVICE WITH GRAPHEN | |
| IL254000A0 (en) | Nucleic acid sequence composition | |
| EP3371194A4 (en) | METHODS AND REAGENTS FOR SEQUENCING PROTEINS | |
| HK1256342A1 (zh) | 環境或生物樣本中的核酸純化 | |
| SG11202003885UA (en) | Reagents and adapters for nucleic acid sequencing and methods for making such reagents and adapters | |
| SG10201913820TA (en) | Nucleic Acid Analysis Apparatus | |
| IL290274A (en) | Methods and reagents for nucleic acid sequencing and related applications | |
| IL273426A (en) | Systems and methods for nucleic acid sequencing | |
| GB2589159B (en) | Nucleic acid sequencing apparatus | |
| EP3277845A4 (en) | Beads for nucleic acid sequencing | |
| GB201506669D0 (en) | Nucleic acid sample enrichment | |
| GB201812474D0 (en) | Nucleic acid construct | |
| EP3508587A4 (en) | DNA SEQUENCING METHOD | |
| GB201721053D0 (en) | DNA polymerases | |
| GB2553907B (en) | Nucleic acid analyzer | |
| RS64086B1 (sr) | Postupak za sekvenciranje nukleinske kiseline | |
| SG11202112704TA (en) | Nucleic acid analysis | |
| IL271510A (en) | Determining the ratio between nucleic acids | |
| GB201701790D0 (en) | Methods for nucleic acid enrichment |