MX2018012297A - Metodo para la produccion de acido lactico. - Google Patents

Metodo para la produccion de acido lactico.

Info

Publication number
MX2018012297A
MX2018012297A MX2018012297A MX2018012297A MX2018012297A MX 2018012297 A MX2018012297 A MX 2018012297A MX 2018012297 A MX2018012297 A MX 2018012297A MX 2018012297 A MX2018012297 A MX 2018012297A MX 2018012297 A MX2018012297 A MX 2018012297A
Authority
MX
Mexico
Prior art keywords
lactic acid
yeast
producing lactic
cultivated
activity
Prior art date
Application number
MX2018012297A
Other languages
English (en)
Inventor
Sauer Michael
Koppram Rakesh
Mattanovich Diethard
ASK Magnus
Original Assignee
Syconium Lactic Acid Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syconium Lactic Acid Gmbh filed Critical Syconium Lactic Acid Gmbh
Publication of MX2018012297A publication Critical patent/MX2018012297A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/395—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01027—L-Lactate dehydrogenase (1.1.1.27)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/01001—Pyruvate decarboxylase (4.1.1.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Botany (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención proporciona un método para producir ácido láctico en un cultivo celular de levadura recombinante mediante la utilización de glucosa como fuente de carbono que comprende una primera etapa de fermentación de semillas para producir biomasa, en donde la levadura se cultiva en un medio de cultivo a un pH de 5 a 7, seguido por una segunda etapa de fermentación de producción con biomasa de la fermentación de semillas para producir ácido láctico, en donde la levadura se cultiva en un medio de cultivo a un pH bajo mediante la utilización de una cepa de levadura que es modificada para tener una actividad de lactato deshidrogenasa (LDH) y opcionalmente tiene una actividad de piruvato descarboxilado (PDC) disminuida o inhibida.
MX2018012297A 2016-04-18 2017-04-14 Metodo para la produccion de acido lactico. MX2018012297A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16165772 2016-04-18
PCT/EP2017/059046 WO2017182403A1 (en) 2016-04-18 2017-04-14 Method for producing lactic acid

Publications (1)

Publication Number Publication Date
MX2018012297A true MX2018012297A (es) 2019-11-21

Family

ID=55808963

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018012297A MX2018012297A (es) 2016-04-18 2017-04-14 Metodo para la produccion de acido lactico.

Country Status (13)

Country Link
US (1) US10947571B2 (es)
EP (1) EP3445845A1 (es)
JP (1) JP7034088B2 (es)
CN (1) CN109715783A (es)
BR (1) BR112018071250A2 (es)
CA (1) CA3020061A1 (es)
CL (1) CL2018002968A1 (es)
CO (1) CO2018011096A2 (es)
IL (1) IL262149B (es)
MX (1) MX2018012297A (es)
UA (1) UA127433C2 (es)
WO (1) WO2017182403A1 (es)
ZA (1) ZA201806519B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019231393A1 (en) * 2018-05-31 2019-12-05 Ngee Ann Polytechnic D-psicose production using probiotic microorganisms
EP3898935A4 (en) * 2018-12-21 2022-10-12 PTT Global Chemical Public Company Limited MODIFIED MICROBIAL STRAINS FOR ENHANCED FRUCTOSE UTILIZATION
CN110305891B (zh) * 2019-07-12 2023-08-08 广东利世康低碳科技有限公司 一种验证CRISPR-Cas9系统敲除产朊假丝酵母目标基因的可行性的方法
WO2021034276A2 (en) * 2019-08-19 2021-02-25 Ptt Global Chemical Public Company Limited Yeast having improvement of lactic acid tolerance and use thereof
TWI730383B (zh) * 2019-08-21 2021-06-11 遠東新世紀股份有限公司 重組型假絲酵母菌菌株及其製備方法與用途
WO2021110870A1 (en) 2019-12-05 2021-06-10 Acib Gmbh Method for producing a fermentation product
CN110904162B (zh) * 2019-12-19 2021-03-23 河南金丹乳酸科技股份有限公司 在乳酸发酵中加快产酸的通气方法
CN113430127B (zh) * 2021-07-07 2024-01-12 江南大学 一种产l-乳酸的重组菌及其应用
WO2023004336A1 (en) * 2021-07-22 2023-01-26 Archer Daniels Midland Company A genetically engineered yeast producing lactic acid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1294728B1 (it) * 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
US7405068B2 (en) 2003-05-02 2008-07-29 Tate & Lyle Ingredients Americas, Inc. Pyruvate producing yeast strain
EP2158323A4 (en) * 2007-05-18 2011-06-22 Microbia Prec Engineering Inc PRODUCTION OF ORGANIC ACID BY PILZ CELLS
EP2128262A1 (en) * 2008-05-28 2009-12-02 Università Degli Studi Di Milano - Bicocca Improved yeast strains for organic acid production
KR102349954B1 (ko) * 2014-07-28 2022-01-11 삼성전자주식회사 산물 생산능이 향상된 효모 및 그를 이용한 산물을 생산하는 방법

Also Published As

Publication number Publication date
US10947571B2 (en) 2021-03-16
JP7034088B2 (ja) 2022-03-11
CO2018011096A2 (es) 2019-04-30
WO2017182403A1 (en) 2017-10-26
IL262149A (en) 2018-11-29
EP3445845A1 (en) 2019-02-27
CA3020061A1 (en) 2017-10-26
CN109715783A (zh) 2019-05-03
UA127433C2 (uk) 2023-08-23
IL262149B (en) 2021-12-01
ZA201806519B (en) 2022-09-28
JP2019513408A (ja) 2019-05-30
US20190127766A1 (en) 2019-05-02
BR112018071250A2 (pt) 2019-02-05
CL2018002968A1 (es) 2019-02-22

Similar Documents

Publication Publication Date Title
MX2018012297A (es) Metodo para la produccion de acido lactico.
MX2021010518A (es) Medios y metodos de fermentacion para producir polisacarido en cultivo celular bacteriano.
MX2009004659A (es) Procedimiento para la produccion biologica de 1,3-propanodiol a partir de glicerina con un alto rendimiento.
NZ603467A (en) Supplementation of fatty acids for improving alcohol productivity
MX2009010224A (es) Microorganismos y metodos para la produccion de 1,2-propanodiol y acetol.
WO2014004616A3 (en) Engineered yeast with improved growth under low aeration
AR082114A1 (es) Metodo para la preparacion de 1,3-propanodiol a partir de sacarosa
PH12021550473A1 (en) Fermentative production of oligosaccharides by total fermentation utilizing a mixed feedstock
MY148450A (en) Process for the preparation of citric acid employing filamentous fungi in a culture medium comprising glycerol
MY172440A (en) A microorganism having enhanced productivity of lactic acid and a process for producing lactic acid using the same
WO2011115439A3 (ko) 5'-크산틸산 및 5'-구아닐산 생산능이 향상된 미생물 및 이를 이용한 5'-크산틸산 또는 5'-구아닐산의 생산방법
WO2011130725A3 (en) Production of organic acids from xylose rich hydrolysate by bacterial fermentation
WO2011106576A3 (en) Methods and compositions for enhanced enzyme activity in fermenting microorganisms
MX2010008812A (es) Produccion aumentada de etanol por celulas bacterianas.
BR112014026172A2 (pt) método para a produção de ácido láctico
AU2016288656A8 (en) Process for producing lactic acid or its salts from fermentation using thermotolerance bacillus bacteria
WO2012161522A3 (ko) Ｌ-오르니틴 생산능이 향상된 코리네박테리움 속 미생물 및 이를 이용한 ｌ-오르니틴의 제조방법
WO2019013493A3 (ko) 고농도 세포 배양 방법을 이용한 다당체의 생산 방법
WO2013012293A3 (ko) 글리세롤 발효 미생물 변이체를 이용하여 디올화합물을 고수율로 생산하는 방법
MY194236A (en) Yeast strain having improved capability for fermenting xylose in the presence of acetic acid
MY200560A (en) Process for producing an organic compound
ES2352633B8 (es) Cepa mutante de lactococcus lactis lactis y método para la producción industrial de acetoína.
PH12018502640A1 (en) A recombinant yeast and a method for producing ethanol using the same
TH128187B (th) วิธีการเตรียม 1,3-โพรเพนไดออลจากซูโครส (Method for the preparation of 1,3-propanediol from sucrose)
TH128187A (th) วิธีการเตรียม 1,3-โพรเพนไดออลจากซูโครส (Method for the preparation of 1,3-propanediol from sucrose)