MX2018000305A - Anticuerpo anti-receptor de transferrina humana que penetra la barrera hematoencefalica. - Google Patents

Anticuerpo anti-receptor de transferrina humana que penetra la barrera hematoencefalica.

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Publication number
MX2018000305A
MX2018000305A MX2018000305A MX2018000305A MX2018000305A MX 2018000305 A MX2018000305 A MX 2018000305A MX 2018000305 A MX2018000305 A MX 2018000305A MX 2018000305 A MX2018000305 A MX 2018000305A MX 2018000305 A MX2018000305 A MX 2018000305A
Authority
MX
Mexico
Prior art keywords
brain barrier
receptor antibody
transferrin receptor
human transferrin
permeating
Prior art date
Application number
MX2018000305A
Other languages
English (en)
Inventor
Sonoda Hiroyuki
Takahashi Kenichi
Original Assignee
Japan Chem Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57585554&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2018000305(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Japan Chem Res filed Critical Japan Chem Res
Publication of MX2018000305A publication Critical patent/MX2018000305A/es

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    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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Abstract

Se da a conocer un medio para convertir compuestos, los cuales tienen actividad fisiológica o farmacológica y son incapaces de pasar a través de la barrera hematoencefálica, a una forma que les permite pasar a través de la barrera hematoencefálica, así como compuestos convertidos de ese modo. El medio es un anticuerpo anti-receptor de transferrina humana, y los compuestos convertidos son conjugados moleculares entre una proteína fisiológicamente activa o un compuesto de bajo peso molecular farmacológicamente activo y un anticuerpo anti-receptor de transferrina humana.
MX2018000305A 2015-06-24 2016-06-24 Anticuerpo anti-receptor de transferrina humana que penetra la barrera hematoencefalica. MX2018000305A (es)

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