MX2017005422A - Inhibidores de histona desacetilasa y sus usos en terapia. - Google Patents

Inhibidores de histona desacetilasa y sus usos en terapia.

Info

Publication number
MX2017005422A
MX2017005422A MX2017005422A MX2017005422A MX2017005422A MX 2017005422 A MX2017005422 A MX 2017005422A MX 2017005422 A MX2017005422 A MX 2017005422A MX 2017005422 A MX2017005422 A MX 2017005422A MX 2017005422 A MX2017005422 A MX 2017005422A
Authority
MX
Mexico
Prior art keywords
histone deacetylase
diheteroaryl
therapy
deacetylase inhibitors
inhibitors
Prior art date
Application number
MX2017005422A
Other languages
English (en)
Spanish (es)
Inventor
Maccormick Somhairle
Joseph Shuttleworth Stephen
Davy Tomassi Cyrille
Richard Liam Cecil Alexander
John Nodes William
Alexandre Silva Franck
Original Assignee
Karus Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Karus Therapeutics Ltd filed Critical Karus Therapeutics Ltd
Publication of MX2017005422A publication Critical patent/MX2017005422A/es

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    • C07—ORGANIC CHEMISTRY
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    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Epidemiology (AREA)
  • Immunology (AREA)
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  • Diabetes (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
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  • Transplantation (AREA)
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  • Communicable Diseases (AREA)
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  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MX2017005422A 2014-10-29 2015-10-29 Inhibidores de histona desacetilasa y sus usos en terapia. MX2017005422A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1419228.0A GB201419228D0 (en) 2014-10-29 2014-10-29 Compounds
PCT/GB2015/053260 WO2016067040A1 (en) 2014-10-29 2015-10-29 Diheteroaryl histone deacetylase inhibitors and their use in therapy

Publications (1)

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MX2017005422A true MX2017005422A (es) 2017-08-24

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US (1) US10407435B2 (enExample)
EP (1) EP3212625A1 (enExample)
JP (1) JP2017532357A (enExample)
KR (1) KR20170081194A (enExample)
CN (1) CN107001340A (enExample)
AU (1) AU2015340305B2 (enExample)
BR (1) BR112017008794A2 (enExample)
CA (1) CA2966072A1 (enExample)
GB (1) GB201419228D0 (enExample)
IL (1) IL251860A0 (enExample)
MX (1) MX2017005422A (enExample)
SG (1) SG11201703492RA (enExample)
WO (1) WO2016067040A1 (enExample)

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IN2015DN03235A (enExample) 2012-11-07 2015-10-02 Karus Therapeutics Ltd
ES2688815T3 (es) 2013-05-10 2018-11-07 Karus Therapeutics Limited Inhibidores de histona desacetilasa novedosos
GB201419264D0 (en) 2014-10-29 2014-12-10 Karus Therapeutics Ltd Compounds
GB201419228D0 (en) 2014-10-29 2014-12-10 Karus Therapeutics Ltd Compounds
US20180141897A1 (en) 2014-12-08 2018-05-24 The Research Foundation For The State University Of New York Anti-fungals targeting the synthesis of fungal shingolipids
WO2018232298A1 (en) 2017-06-16 2018-12-20 The Research Foundation For The State University Of New York Anti-fungals compounds targeting the synthesis of fungal sphingolipids
BR112021026334A2 (pt) 2019-06-27 2022-05-10 Medstar Health Macrófagos ativados por hdac6, composições, e usos dos mesmos
US11850233B2 (en) 2019-10-28 2023-12-26 Matibur Rahaman Zamadar Reduced adaptive microbial resistance treatment for flesh eating disease (necrotizing fasciitis)
CN112237994B (zh) * 2020-09-21 2022-09-13 昆明冶金研究院有限公司 一种多金属硫化矿硫化锌抑制剂及其制备方法与应用

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CN107001340A (zh) 2017-08-01
BR112017008794A2 (pt) 2017-12-26
AU2015340305B2 (en) 2018-12-06
JP2017532357A (ja) 2017-11-02
CA2966072A1 (en) 2016-05-06
GB201419228D0 (en) 2014-12-10
KR20170081194A (ko) 2017-07-11
US10407435B2 (en) 2019-09-10
US20170313712A1 (en) 2017-11-02
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