IL251860A0 - Dithyroaryl histone deacetylase inhibitors and their use in therapy - Google Patents

Dithyroaryl histone deacetylase inhibitors and their use in therapy

Info

Publication number
IL251860A0
IL251860A0 IL251860A IL25186017A IL251860A0 IL 251860 A0 IL251860 A0 IL 251860A0 IL 251860 A IL251860 A IL 251860A IL 25186017 A IL25186017 A IL 25186017A IL 251860 A0 IL251860 A0 IL 251860A0
Authority
IL
Israel
Prior art keywords
diheteroaryl
therapy
histone deacetylase
deacetylase inhibitors
inhibitors
Prior art date
Application number
IL251860A
Other languages
English (en)
Hebrew (he)
Original Assignee
Karus Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Karus Therapeutics Ltd filed Critical Karus Therapeutics Ltd
Publication of IL251860A0 publication Critical patent/IL251860A0/en

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    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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IL251860A 2014-10-29 2017-04-23 Dithyroaryl histone deacetylase inhibitors and their use in therapy IL251860A0 (en)

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GBGB1419228.0A GB201419228D0 (en) 2014-10-29 2014-10-29 Compounds
PCT/GB2015/053260 WO2016067040A1 (en) 2014-10-29 2015-10-29 Diheteroaryl histone deacetylase inhibitors and their use in therapy

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KR (1) KR20170081194A (enExample)
CN (1) CN107001340A (enExample)
AU (1) AU2015340305B2 (enExample)
BR (1) BR112017008794A2 (enExample)
CA (1) CA2966072A1 (enExample)
GB (1) GB201419228D0 (enExample)
IL (1) IL251860A0 (enExample)
MX (1) MX2017005422A (enExample)
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US9676765B2 (en) * 2012-11-07 2017-06-13 Karus Therapeutics Limited Histone deacetylase inhibitors and their use in therapy
NZ714283A (en) 2013-05-10 2020-04-24 Karus Therapeutics Ltd Novel histone deacetylase inhibitors
GB201419228D0 (en) 2014-10-29 2014-12-10 Karus Therapeutics Ltd Compounds
GB201419264D0 (en) 2014-10-29 2014-12-10 Karus Therapeutics Ltd Compounds
WO2016094307A1 (en) 2014-12-08 2016-06-16 The Research Foundation For The State University Of New York Anti-fungals targeting the synthesis of fungal shingolipids
EP3638649A4 (en) 2017-06-16 2021-03-17 The Research Foundation for The State University of New York Anti-fungals compounds targeting the synthesis of fungal sphingolipids
CA3144985A1 (en) 2019-06-27 2020-12-30 The George Washington University, A Congressionally Chartered Not-For-Profit Corporation Hdac6-activated macrophages, compositions, and uses thereof
US11850233B2 (en) 2019-10-28 2023-12-26 Matibur Rahaman Zamadar Reduced adaptive microbial resistance treatment for flesh eating disease (necrotizing fasciitis)
CN112237994B (zh) * 2020-09-21 2022-09-13 昆明冶金研究院有限公司 一种多金属硫化矿硫化锌抑制剂及其制备方法与应用

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EP3212625A1 (en) 2017-09-06
US10407435B2 (en) 2019-09-10
WO2016067040A1 (en) 2016-05-06
KR20170081194A (ko) 2017-07-11
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