IL251860A0 - Dithyroaryl histone deacetylase inhibitors and their use in therapy - Google Patents

Dithyroaryl histone deacetylase inhibitors and their use in therapy

Info

Publication number
IL251860A0
IL251860A0 IL251860A IL25186017A IL251860A0 IL 251860 A0 IL251860 A0 IL 251860A0 IL 251860 A IL251860 A IL 251860A IL 25186017 A IL25186017 A IL 25186017A IL 251860 A0 IL251860 A0 IL 251860A0
Authority
IL
Israel
Prior art keywords
diheteroaryl
therapy
histone deacetylase
deacetylase inhibitors
inhibitors
Prior art date
Application number
IL251860A
Other languages
English (en)
Hebrew (he)
Original Assignee
Karus Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Karus Therapeutics Ltd filed Critical Karus Therapeutics Ltd
Publication of IL251860A0 publication Critical patent/IL251860A0/en

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    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL251860A 2014-10-29 2017-04-23 Dithyroaryl histone deacetylase inhibitors and their use in therapy IL251860A0 (en)

Applications Claiming Priority (2)

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GBGB1419228.0A GB201419228D0 (en) 2014-10-29 2014-10-29 Compounds
PCT/GB2015/053260 WO2016067040A1 (en) 2014-10-29 2015-10-29 Diheteroaryl histone deacetylase inhibitors and their use in therapy

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EP (1) EP3212625A1 (enExample)
JP (1) JP2017532357A (enExample)
KR (1) KR20170081194A (enExample)
CN (1) CN107001340A (enExample)
AU (1) AU2015340305B2 (enExample)
BR (1) BR112017008794A2 (enExample)
CA (1) CA2966072A1 (enExample)
GB (1) GB201419228D0 (enExample)
IL (1) IL251860A0 (enExample)
MX (1) MX2017005422A (enExample)
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IN2015DN03235A (enExample) * 2012-11-07 2015-10-02 Karus Therapeutics Ltd
PT2994465T (pt) 2013-05-10 2018-10-25 Karus Therapeutics Ltd Novos inibidores de histona desacetilase
GB201419264D0 (en) 2014-10-29 2014-12-10 Karus Therapeutics Ltd Compounds
GB201419228D0 (en) 2014-10-29 2014-12-10 Karus Therapeutics Ltd Compounds
WO2016094307A1 (en) 2014-12-08 2016-06-16 The Research Foundation For The State University Of New York Anti-fungals targeting the synthesis of fungal shingolipids
US11414378B2 (en) 2017-06-16 2022-08-16 The Research Foundation For The State University Of New York Anti-fungals compounds targeting the synthesis of fungal sphingolipids
JP2022538284A (ja) 2019-06-27 2022-09-01 ザ ジョージ ワシントン ユニバーシティ， ア コングレッショナリー チャータード ノット－フォー－プロフィット コーポレイション Ｈｄａｃ６活性化マクロファージ、その組成物および使用
US11850233B2 (en) 2019-10-28 2023-12-26 Matibur Rahaman Zamadar Reduced adaptive microbial resistance treatment for flesh eating disease (necrotizing fasciitis)
CN112237994B (zh) * 2020-09-21 2022-09-13 昆明冶金研究院有限公司 一种多金属硫化矿硫化锌抑制剂及其制备方法与应用

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US20170313712A1 (en) 2017-11-02
WO2016067040A1 (en) 2016-05-06
KR20170081194A (ko) 2017-07-11
AU2015340305A1 (en) 2017-05-18
MX2017005422A (es) 2017-08-24
SG11201703492RA (en) 2017-05-30
CA2966072A1 (en) 2016-05-06
BR112017008794A2 (pt) 2017-12-26
CN107001340A (zh) 2017-08-01
US10407435B2 (en) 2019-09-10
EP3212625A1 (en) 2017-09-06
AU2015340305B2 (en) 2018-12-06
JP2017532357A (ja) 2017-11-02

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