PL3240777T3 - Inhibitory arginazy oraz ich zastosowania terapeutyczne - Google Patents

Inhibitory arginazy oraz ich zastosowania terapeutyczne

Info

Publication number
PL3240777T3
PL3240777T3 PL15823405T PL15823405T PL3240777T3 PL 3240777 T3 PL3240777 T3 PL 3240777T3 PL 15823405 T PL15823405 T PL 15823405T PL 15823405 T PL15823405 T PL 15823405T PL 3240777 T3 PL3240777 T3 PL 3240777T3
Authority
PL
Poland
Prior art keywords
therapeutic applications
arginase inhibitors
arginase
inhibitors
therapeutic
Prior art date
Application number
PL15823405T
Other languages
English (en)
Inventor
Roman Błaszczyk
Joanna Brzezińska
Adam A Gołębiowski
Jacek Olczak
Original Assignee
Oncoarendi Therapeutics Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncoarendi Therapeutics Sa filed Critical Oncoarendi Therapeutics Sa
Publication of PL3240777T3 publication Critical patent/PL3240777T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/96—Sulfur atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dentistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL15823405T 2014-12-29 2015-12-22 Inhibitory arginazy oraz ich zastosowania terapeutyczne PL3240777T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462097163P 2014-12-29 2014-12-29
PL410665A PL410665A1 (pl) 2014-12-29 2014-12-29 Inhibitory arginazy oraz ich zastosowania terapeutyczne
PCT/PL2015/050073 WO2016108707A1 (en) 2014-12-29 2015-12-22 Arginase inhibitors and their therapeutic applications
EP15823405.4A EP3240777B1 (en) 2014-12-29 2015-12-22 Arginase inhibitors and their therapeutic applications

Publications (1)

Publication Number Publication Date
PL3240777T3 true PL3240777T3 (pl) 2019-10-31

Family

ID=56234474

Family Applications (2)

Application Number Title Priority Date Filing Date
PL410665A PL410665A1 (pl) 2014-12-29 2014-12-29 Inhibitory arginazy oraz ich zastosowania terapeutyczne
PL15823405T PL3240777T3 (pl) 2014-12-29 2015-12-22 Inhibitory arginazy oraz ich zastosowania terapeutyczne

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL410665A PL410665A1 (pl) 2014-12-29 2014-12-29 Inhibitory arginazy oraz ich zastosowania terapeutyczne

Country Status (7)

Country Link
US (1) US10329310B2 (pl)
EP (1) EP3240777B1 (pl)
CN (1) CN107406464B (pl)
AU (1) AU2015372690A1 (pl)
CA (1) CA2973474A1 (pl)
PL (2) PL410665A1 (pl)
WO (1) WO2016108707A1 (pl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11845767B2 (en) 2019-06-14 2023-12-19 Rijksuniversiteit Groningen Arginase inhibitors

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL417066A1 (pl) 2016-05-04 2017-11-06 Oncoarendi Therapeutics Spółka Z Ograniczoną Odpowiedzialnością Inhibitory arginazy oraz ich zastosowania terapeutyczne
JP7317841B2 (ja) 2018-02-17 2023-07-31 アストラゼネカ・アクチエボラーグ アルギナーゼインヒビタ及びその使用方法
CA3091805A1 (en) 2018-03-05 2019-09-12 Arcus Biosciences, Inc. Arginase inhibitors
EP3765006A4 (en) 2018-03-13 2022-02-23 Merck Sharp & Dohme Corp. ARGINASE INHIBITORS AND METHODS OF USE
US10851099B2 (en) 2018-03-29 2020-12-01 Oncoarendi Therapeutics S.A. Dipeptide piperidine derivatives
US11274111B2 (en) 2018-06-20 2022-03-15 Merck Sharp & Dohme Corp. Arginase inhibitors and methods of use
DK3873903T3 (da) 2018-10-31 2024-04-02 Gilead Sciences Inc Substituerede 6-azabenzimidazolforbindelser som hpk1-hæmmere
WO2020092528A1 (en) 2018-10-31 2020-05-07 Gilead Sciences, Inc. Substituted 6-azabenzimidazole compounds having hpk1 inhibitory activity
TWI828800B (zh) * 2018-11-16 2024-01-11 美商阿克思生物科學有限公司 Arg1及/或arg2之抑制劑
WO2020131598A1 (en) 2018-12-18 2020-06-25 Merck Sharp & Dohme Corp. Arginase inhibitors and methods of use
SMT202300337T1 (it) 2019-02-08 2023-11-13 Astrazeneca Ab Inibitori di arginasi e relativi metodi d'uso
TWI826690B (zh) 2019-05-23 2023-12-21 美商基利科學股份有限公司 經取代之烯吲哚酮化物及其用途
US20220267356A1 (en) * 2019-07-23 2022-08-25 Astrazeneca Ab Arginase inhibitors and methods of use thereof
TW202228720A (zh) 2020-12-22 2022-08-01 波蘭商昂科艾倫迪治療法股份公司 精胺酸酶抑制劑及其使用方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3507486B2 (ja) 1991-03-15 2004-03-15 アムジエン・インコーポレーテツド 顆粒球コロニー刺激因子の肺内投与
US5451569A (en) 1994-04-19 1995-09-19 Hong Kong University Of Science And Technology R & D Corporation Limited Pulmonary drug delivery system
AU9797998A (en) 1997-10-10 1999-05-03 Trustees Of The University Of Pennsylvania, The Compositions and methods for inhibiting arginase activity
EP2083812B1 (en) 2006-11-21 2017-04-05 Rijksuniversiteit Groningen Use of arginase inhibitors in the treatment of asthma and allergic rhinitis
RS58965B1 (sr) * 2009-01-26 2019-08-30 Univ Pennsylvania Inhibitori arginaze i postupci upotrebe
BR112012027034B1 (pt) 2010-04-22 2020-10-13 Mars, Incorporated compostos inibidores de arginase, composição farmacêutica compreendendo o referido composto, método in vitro para inibição de arginase i e ii e uso do referido composto
HRP20160305T1 (hr) 2010-10-26 2016-07-01 Mars, Incorporated Borati kao inhibitori arginaze
US8894970B2 (en) 2010-12-31 2014-11-25 Corridor Pharmaceuticals, Inc. Arginase inhibitors and methods of use thereof
CN104244932B (zh) 2011-10-19 2017-02-22 马尔斯公司 精氨酸酶抑制剂和其治疗应用
EP2852598B3 (en) 2012-04-18 2016-10-19 Mars, Incorporated Ring constrained analogs as arginase inhibitors

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11845767B2 (en) 2019-06-14 2023-12-19 Rijksuniversiteit Groningen Arginase inhibitors

Also Published As

Publication number Publication date
EP3240777B1 (en) 2019-07-24
AU2015372690A1 (en) 2017-07-27
CN107406464B (zh) 2019-03-19
CN107406464A (zh) 2017-11-28
US10329310B2 (en) 2019-06-25
US20180009830A1 (en) 2018-01-11
WO2016108707A1 (en) 2016-07-07
CA2973474A1 (en) 2016-07-07
EP3240777A1 (en) 2017-11-08
PL410665A1 (pl) 2016-07-04
CN107406464A8 (zh) 2018-01-12

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