PL3240777T3 - Inhibitory arginazy oraz ich zastosowania terapeutyczne - Google Patents

Inhibitory arginazy oraz ich zastosowania terapeutyczne

Info

Publication number
PL3240777T3
PL3240777T3 PL15823405T PL15823405T PL3240777T3 PL 3240777 T3 PL3240777 T3 PL 3240777T3 PL 15823405 T PL15823405 T PL 15823405T PL 15823405 T PL15823405 T PL 15823405T PL 3240777 T3 PL3240777 T3 PL 3240777T3
Authority
PL
Poland
Prior art keywords
therapeutic applications
arginase inhibitors
arginase
inhibitors
therapeutic
Prior art date
Application number
PL15823405T
Other languages
English (en)
Inventor
Roman Błaszczyk
Joanna Brzezińska
Adam A Gołębiowski
Jacek Olczak
Original Assignee
Oncoarendi Therapeutics Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncoarendi Therapeutics Sa filed Critical Oncoarendi Therapeutics Sa
Publication of PL3240777T3 publication Critical patent/PL3240777T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/96—Sulfur atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dentistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
PL15823405T 2014-12-29 2015-12-22 Inhibitory arginazy oraz ich zastosowania terapeutyczne PL3240777T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462097163P 2014-12-29 2014-12-29
PL410665A PL410665A1 (pl) 2014-12-29 2014-12-29 Inhibitory arginazy oraz ich zastosowania terapeutyczne
PCT/PL2015/050073 WO2016108707A1 (en) 2014-12-29 2015-12-22 Arginase inhibitors and their therapeutic applications
EP15823405.4A EP3240777B1 (en) 2014-12-29 2015-12-22 Arginase inhibitors and their therapeutic applications

Publications (1)

Publication Number Publication Date
PL3240777T3 true PL3240777T3 (pl) 2019-10-31

Family

ID=56234474

Family Applications (2)

Application Number Title Priority Date Filing Date
PL410665A PL410665A1 (pl) 2014-12-29 2014-12-29 Inhibitory arginazy oraz ich zastosowania terapeutyczne
PL15823405T PL3240777T3 (pl) 2014-12-29 2015-12-22 Inhibitory arginazy oraz ich zastosowania terapeutyczne

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL410665A PL410665A1 (pl) 2014-12-29 2014-12-29 Inhibitory arginazy oraz ich zastosowania terapeutyczne

Country Status (7)

Country Link
US (1) US10329310B2 (pl)
EP (1) EP3240777B1 (pl)
CN (1) CN107406464B (pl)
AU (1) AU2015372690A1 (pl)
CA (1) CA2973474A1 (pl)
PL (2) PL410665A1 (pl)
WO (1) WO2016108707A1 (pl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11845767B2 (en) 2019-06-14 2023-12-19 Rijksuniversiteit Groningen Arginase inhibitors

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL417066A1 (pl) 2016-05-04 2017-11-06 Oncoarendi Therapeutics Spółka Z Ograniczoną Odpowiedzialnością Inhibitory arginazy oraz ich zastosowania terapeutyczne
PT3752251T (pt) 2018-02-17 2026-01-13 Astrazeneca Ab Inibidores da arginase e métodos de utilização destes
SG11202008113RA (en) 2018-03-05 2020-09-29 Arcus Biosciences Inc Arginase inhibitors
US12215116B2 (en) 2018-03-13 2025-02-04 Merck Sharp & Dohme Llc Arginase inhibitors and methods of use
AU2019246728A1 (en) 2018-03-29 2020-08-27 Oncoarendi Therapeutics S.A. Dipeptide piperidine derivatives
US11274111B2 (en) 2018-06-20 2022-03-15 Merck Sharp & Dohme Corp. Arginase inhibitors and methods of use
KR102658602B1 (ko) 2018-10-31 2024-04-19 길리애드 사이언시즈, 인코포레이티드 Hpk1 억제 활성을 갖는 치환된 6-아자벤즈이미다졸 화합물
SG11202103839UA (en) 2018-10-31 2021-05-28 Gilead Sciences Inc Substituted 6-azabenzimidazole compounds as hpk1 inhibitors
CA3120196A1 (en) * 2018-11-16 2020-05-22 Arcus Biosciences, Inc. Inhibitors of arg1 and/or arg2
WO2020131598A1 (en) 2018-12-18 2020-06-25 Merck Sharp & Dohme Corp. Arginase inhibitors and methods of use
BR112021015581A2 (pt) * 2019-02-08 2021-10-05 Astrazeneca Ab Inibidores de arginase e seus métodos de uso
US11453681B2 (en) 2019-05-23 2022-09-27 Gilead Sciences, Inc. Substituted eneoxindoles and uses thereof
CN119119095A (zh) * 2019-07-23 2024-12-13 阿斯利康(瑞典)有限公司 精氨酸酶抑制剂及其使用方法
TW202228720A (zh) 2020-12-22 2022-08-01 波蘭商昂科艾倫迪治療法股份公司 精胺酸酶抑制劑及其使用方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU643141B2 (en) 1991-03-15 1993-11-04 Amgen, Inc. Pulmonary administration of granulocyte colony stimulating factor
US5451569A (en) 1994-04-19 1995-09-19 Hong Kong University Of Science And Technology R & D Corporation Limited Pulmonary drug delivery system
AU9797998A (en) 1997-10-10 1999-05-03 Trustees Of The University Of Pennsylvania, The Compositions and methods for inhibiting arginase activity
CA2669300A1 (en) 2006-11-21 2008-05-29 Rijksuniversiteit Groningen Use of arginase inhibitors in the treatment of asthma and allergic rhinitis
RS58965B1 (sr) * 2009-01-26 2019-08-30 Univ Pennsylvania Inhibitori arginaze i postupci upotrebe
MX348422B (es) 2010-04-22 2017-06-12 Mars Inc Inhibidores de arginasa y sus aplicaciones terapeuticas.
MX336381B (es) 2010-10-26 2016-01-18 Mars Inc Boronatos como inhibidores de arginasa.
RU2019121905A (ru) 2010-12-31 2019-09-03 Астразенека Юкей Лимитед Ингибиторы аргиназы и способы их применения
MX343534B (es) 2011-10-19 2016-11-09 Mars Inc Inhibidores de arginasa y sus aplicaciones terapeuticas.
JP6152167B2 (ja) 2012-04-18 2017-06-21 マーズ インコーポレイテッド アルギナーゼ阻害剤としての環拘束性類似体

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11845767B2 (en) 2019-06-14 2023-12-19 Rijksuniversiteit Groningen Arginase inhibitors

Also Published As

Publication number Publication date
PL410665A1 (pl) 2016-07-04
EP3240777A1 (en) 2017-11-08
WO2016108707A1 (en) 2016-07-07
US20180009830A1 (en) 2018-01-11
AU2015372690A1 (en) 2017-07-27
CN107406464A8 (zh) 2018-01-12
CN107406464A (zh) 2017-11-28
CN107406464B (zh) 2019-03-19
CA2973474A1 (en) 2016-07-07
US10329310B2 (en) 2019-06-25
EP3240777B1 (en) 2019-07-24

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