MX2009005370A - Uso de inhibidores de arginasa en el tratamiento de asma y rinitis alergica. - Google Patents

Uso de inhibidores de arginasa en el tratamiento de asma y rinitis alergica.

Info

Publication number
MX2009005370A
MX2009005370A MX2009005370A MX2009005370A MX2009005370A MX 2009005370 A MX2009005370 A MX 2009005370A MX 2009005370 A MX2009005370 A MX 2009005370A MX 2009005370 A MX2009005370 A MX 2009005370A MX 2009005370 A MX2009005370 A MX 2009005370A
Authority
MX
Mexico
Prior art keywords
allergic rhinitis
asthma
treatment
arginase inhibitors
asthmatic
Prior art date
Application number
MX2009005370A
Other languages
English (en)
Inventor
Hermanus Meurs
Johan Zaagsma
Harm Maarsingh
Michel Van Duin
Original Assignee
Univ Groningen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Groningen filed Critical Univ Groningen
Publication of MX2009005370A publication Critical patent/MX2009005370A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

La presente invención se refiere al uso de un inhibidor de arginasa para la preparación de un medicamento para terapia de mantenimiento profiláctico de un paciente asmático o alérgico previniendo la obstrucción de vías respiratorias superiores e inferiores, en particular la obstrucción bronquial y/o hiperactividad de las vías respiratorias inducidas por alérgeno. Los pacientes son asmáticos o tienen rinitis alérgica. Preferiblemente, el inhibidor de arginasa es ácido 2(S)-amino-6-boronohexanoico (ABH).
MX2009005370A 2006-11-21 2007-10-30 Uso de inhibidores de arginasa en el tratamiento de asma y rinitis alergica. MX2009005370A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06024111 2006-11-21
PCT/EP2007/009449 WO2008061612A1 (en) 2006-11-21 2007-10-30 Use of arginase inhibitors in the treatment of asthma and allergic rhinitis

Publications (1)

Publication Number Publication Date
MX2009005370A true MX2009005370A (es) 2009-10-16

Family

ID=38824483

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009005370A MX2009005370A (es) 2006-11-21 2007-10-30 Uso de inhibidores de arginasa en el tratamiento de asma y rinitis alergica.

Country Status (7)

Country Link
US (2) US20100056480A1 (es)
EP (1) EP2083812B1 (es)
JP (3) JP2010510257A (es)
CA (1) CA2669300A1 (es)
ES (1) ES2633094T3 (es)
MX (1) MX2009005370A (es)
WO (1) WO2008061612A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2488390C2 (ru) * 2008-12-29 2013-07-27 Тартуский Университет Ингибиторы аргиназы для лечения депрессии
SI2389352T1 (sl) * 2009-01-26 2019-08-30 The Trustees Of The University Of Pennsylvania, Center For Technology Transfer Inhibitorji arginaze in postopki uporabe
RS54750B1 (sr) 2010-10-26 2016-10-31 Mars Inc Borati kao inhibitori arginaze
KR101613252B1 (ko) * 2013-05-03 2016-04-18 고려대학교 산학협력단 아르기나아제 억제제를 함유하는 비만 및 지방간 예방 또는 치료용 조성물
PL410665A1 (pl) 2014-12-29 2016-07-04 Oncoarendi Therapeutics Spółka Z Ograniczoną Odpowiedzialnością Inhibitory arginazy oraz ich zastosowania terapeutyczne
PL417066A1 (pl) 2016-05-04 2017-11-06 Oncoarendi Therapeutics Spółka Z Ograniczoną Odpowiedzialnością Inhibitory arginazy oraz ich zastosowania terapeutyczne
AU2019211067A1 (en) 2018-01-28 2020-08-13 Universite De Geneve Arginase suppression for cancer treatment
CA3094939A1 (en) 2018-03-29 2019-10-03 Oncoarendi Therapeutics S.A. Dipeptide piperidine derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2778562B1 (fr) * 1998-05-14 2000-08-04 Sephra Composition pharmaceutique, hygienique et/ou cosmetique contenant de l'eau de mer et de l'arginine
WO2003073990A2 (en) * 2002-03-01 2003-09-12 Children's Hospital Medical Center Treatment for asthma or allergies
CA2515929C (en) * 2003-02-14 2013-11-19 Children's Hospital & Research Center At Oakland Treatment of conditions associated with decreased nitric oxide bioavailability, including elevated arginase conditions
MXPA05009251A (es) * 2003-03-04 2005-10-19 Wyeth Corp Composiciones y metodos para diagnosticar y tratar asma u otras enfermedades alergicas o inflamatorias.

Also Published As

Publication number Publication date
EP2083812A1 (en) 2009-08-05
US20100056480A1 (en) 2010-03-04
JP6234899B2 (ja) 2017-11-22
WO2008061612A1 (en) 2008-05-29
JP2014237703A (ja) 2014-12-18
EP2083812B1 (en) 2017-04-05
CA2669300A1 (en) 2008-05-29
JP2010510257A (ja) 2010-04-02
US20150164930A1 (en) 2015-06-18
JP2017061515A (ja) 2017-03-30
ES2633094T3 (es) 2017-09-19

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