JP2017532357A - ジヘテロアリールヒストンデアセチラーゼインヒビターおよび治療におけるその使用 - Google Patents

ジヘテロアリールヒストンデアセチラーゼインヒビターおよび治療におけるその使用 Download PDF

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JP2017532357A
JP2017532357A JP2017522844A JP2017522844A JP2017532357A JP 2017532357 A JP2017532357 A JP 2017532357A JP 2017522844 A JP2017522844 A JP 2017522844A JP 2017522844 A JP2017522844 A JP 2017522844A JP 2017532357 A JP2017532357 A JP 2017532357A
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alkyl
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compound according
heteroaryl
independently selected
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JP2017532357A5 (enExample
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スティーブン ジョセフ シャトルワース，
スティーブン ジョセフ シャトルワース，
アレクサンダー リチャード リアム セシル，
アレクサンダー リチャード リアム セシル，
ソマール マクコーミック，
ソマール マクコーミック，
ウィリアム ジョン ノーズ，
ウィリアム ジョン ノーズ，
シリル デイビー トマッシ，
シリル デイビー トマッシ，
フランク アレクサンドル シルバ，
フランク アレクサンドル シルバ，
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カルス セラピューティクス リミテッド
カルス セラピューティクス リミテッド
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Publication of JP2017532357A publication Critical patent/JP2017532357A/ja
Publication of JP2017532357A5 publication Critical patent/JP2017532357A5/ja
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    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
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JP2017522844A 2014-10-29 2015-10-29 ジヘテロアリールヒストンデアセチラーゼインヒビターおよび治療におけるその使用 Pending JP2017532357A (ja)

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GB1419228.0 2014-10-29
GBGB1419228.0A GB201419228D0 (en) 2014-10-29 2014-10-29 Compounds
PCT/GB2015/053260 WO2016067040A1 (en) 2014-10-29 2015-10-29 Diheteroaryl histone deacetylase inhibitors and their use in therapy

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JP2017532357A true JP2017532357A (ja) 2017-11-02
JP2017532357A5 JP2017532357A5 (enExample) 2018-08-30

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US (1) US10407435B2 (enExample)
EP (1) EP3212625A1 (enExample)
JP (1) JP2017532357A (enExample)
KR (1) KR20170081194A (enExample)
CN (1) CN107001340A (enExample)
AU (1) AU2015340305B2 (enExample)
BR (1) BR112017008794A2 (enExample)
CA (1) CA2966072A1 (enExample)
GB (1) GB201419228D0 (enExample)
IL (1) IL251860A0 (enExample)
MX (1) MX2017005422A (enExample)
SG (1) SG11201703492RA (enExample)
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US10407435B2 (en) 2019-09-10
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