MX2016006316A - Inhibidores de mtor para potenciar la respuesta inmunitaria. - Google Patents

Inhibidores de mtor para potenciar la respuesta inmunitaria.

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Publication number
MX2016006316A
MX2016006316A MX2016006316A MX2016006316A MX2016006316A MX 2016006316 A MX2016006316 A MX 2016006316A MX 2016006316 A MX2016006316 A MX 2016006316A MX 2016006316 A MX2016006316 A MX 2016006316A MX 2016006316 A MX2016006316 A MX 2016006316A
Authority
MX
Mexico
Prior art keywords
immune response
enhancing
mtor inhibitors
mtor
immune
Prior art date
Application number
MX2016006316A
Other languages
English (en)
Inventor
Leon Murphy
Joan Mannick
David Jonathan Glass
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2016006316A publication Critical patent/MX2016006316A/es

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
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Abstract

La presente invención se refiere, en parte, a composiciones y métodos para potenciar una respuesta inmunitaria mediante la inhibición parcial de mTOR, por ejemplo, con bajas dosis inmunopotenciadoras de un inhibidor de mTOR, tal como RAD001.
MX2016006316A 2013-11-13 2014-11-13 Inhibidores de mtor para potenciar la respuesta inmunitaria. MX2016006316A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361903636P 2013-11-13 2013-11-13
US201462027121P 2014-07-21 2014-07-21
US201462052629P 2014-09-19 2014-09-19
US201462076142P 2014-11-06 2014-11-06
PCT/US2014/065408 WO2015073644A1 (en) 2013-11-13 2014-11-13 Mtor inhibitors for enhancing the immune response

Publications (1)

Publication Number Publication Date
MX2016006316A true MX2016006316A (es) 2016-07-26

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016006316A MX2016006316A (es) 2013-11-13 2014-11-13 Inhibidores de mtor para potenciar la respuesta inmunitaria.

Country Status (12)

Country Link
US (4) US20150140036A1 (es)
EP (1) EP3068435A1 (es)
JP (2) JP2016537345A (es)
KR (1) KR20160084438A (es)
CN (1) CN105899232A (es)
AU (3) AU2014348657A1 (es)
BR (1) BR112016010716A8 (es)
CA (1) CA2929181A1 (es)
EA (1) EA201690987A1 (es)
MX (1) MX2016006316A (es)
TW (1) TWI679976B (es)
WO (1) WO2015073644A1 (es)

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