MX2021002455A - Metodos para tratar tumores de celulas epitelioides. - Google Patents
Metodos para tratar tumores de celulas epitelioides.Info
- Publication number
- MX2021002455A MX2021002455A MX2021002455A MX2021002455A MX2021002455A MX 2021002455 A MX2021002455 A MX 2021002455A MX 2021002455 A MX2021002455 A MX 2021002455A MX 2021002455 A MX2021002455 A MX 2021002455A MX 2021002455 A MX2021002455 A MX 2021002455A
- Authority
- MX
- Mexico
- Prior art keywords
- cell tumors
- methods
- epithelioid cell
- treating
- treating epithelioid
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 210000003237 epithelioid cell Anatomy 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 102000009027 Albumins Human genes 0.000 abstract 1
- 108010088751 Albumins Proteins 0.000 abstract 1
- 208000000360 Perivascular Epithelioid Cell Neoplasms Diseases 0.000 abstract 1
- 229940124302 mTOR inhibitor Drugs 0.000 abstract 1
- 239000003628 mammalian target of rapamycin inhibitor Substances 0.000 abstract 1
- 239000002105 nanoparticle Substances 0.000 abstract 1
- 208000028732 neoplasm with perivascular epithelioid cell differentiation Diseases 0.000 abstract 1
- 201000005207 perivascular epithelioid cell tumor Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Nanotechnology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente invención proporciona métodos y composiciones para tratar tumores de células epitelioides (como PEComa) mediante la administración de una composición que comprende nanopartículas que comprenden un inhibidor mTOR y una albúmina.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562186252P | 2015-06-29 | 2015-06-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021002455A true MX2021002455A (es) | 2021-05-14 |
Family
ID=57609139
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017016322A MX2017016322A (es) | 2015-06-29 | 2016-06-29 | Metodos para tratar tumores de celulas epitelioides. |
MX2021002455A MX2021002455A (es) | 2015-06-29 | 2017-12-14 | Metodos para tratar tumores de celulas epitelioides. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017016322A MX2017016322A (es) | 2015-06-29 | 2016-06-29 | Metodos para tratar tumores de celulas epitelioides. |
Country Status (26)
Country | Link |
---|---|
US (2) | US10973806B2 (es) |
EP (2) | EP3998069A1 (es) |
JP (3) | JP6987644B2 (es) |
KR (2) | KR20230165356A (es) |
CN (3) | CN116585310A (es) |
AU (2) | AU2016285720C1 (es) |
BR (1) | BR112017027954B1 (es) |
CA (1) | CA2990693C (es) |
CL (1) | CL2017003456A1 (es) |
CY (1) | CY1124926T1 (es) |
DK (1) | DK3313401T3 (es) |
EA (2) | EA202092187A1 (es) |
ES (1) | ES2897991T3 (es) |
HK (1) | HK1247094A1 (es) |
HR (1) | HRP20211718T1 (es) |
HU (1) | HUE057175T2 (es) |
IL (1) | IL256274B2 (es) |
LT (1) | LT3313401T (es) |
MX (2) | MX2017016322A (es) |
PL (1) | PL3313401T3 (es) |
PT (1) | PT3313401T (es) |
RS (1) | RS62743B1 (es) |
SG (1) | SG10202107198SA (es) |
SI (1) | SI3313401T1 (es) |
WO (1) | WO2017004249A1 (es) |
ZA (1) | ZA201708567B (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2007334360B2 (en) | 2006-12-14 | 2013-10-17 | Abraxis Bioscience, Llc | Breast cancer therapy based on hormone receptor status with nanoparticles comprising taxane |
ME03596B (me) | 2009-04-15 | 2020-07-20 | Abraxis Bioscience Llc | Kompozicije nanočesтica bez priona i postupci povezani sa njima |
US10660965B2 (en) | 2010-03-29 | 2020-05-26 | Abraxis Bioscience, Llc | Methods of enhancing drug delivery and effectiveness of therapeutic agents |
SG194623A1 (en) | 2011-04-28 | 2013-12-30 | Abraxis Bioscience Llc | Intravascular delivery of nanoparticle compositions and uses thereof |
MX354859B (es) | 2011-12-14 | 2018-03-23 | Abraxis Bioscience Llc | Uso de excipientes polimericos para liofilizacion o congelacion de particulas. |
US9511046B2 (en) | 2013-01-11 | 2016-12-06 | Abraxis Bioscience, Llc | Methods of treating pancreatic cancer |
EP3698784A1 (en) | 2013-03-12 | 2020-08-26 | Abraxis BioScience, LLC | Methods of treating lung cancer |
CN110934852A (zh) | 2013-03-14 | 2020-03-31 | 阿布拉科斯生物科学有限公司 | 治疗膀胱癌的方法 |
US10527604B1 (en) | 2015-03-05 | 2020-01-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and paclitaxel |
US10705070B1 (en) | 2015-03-05 | 2020-07-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and poorly water soluble drug |
CN116585310A (zh) | 2015-06-29 | 2023-08-15 | 阿布拉科斯生物科学有限公司 | 治疗上皮样细胞肿瘤的方法 |
EP3768268A4 (en) | 2018-03-20 | 2022-02-23 | Abraxis BioScience, LLC | METHOD OF TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS BY ADMINISTRATION OF NANOPARTICLES OF AN MTOR INHIBITOR AND AN ALBUMINE |
WO2019226685A1 (en) * | 2018-05-22 | 2019-11-28 | Abraxis Bioscience, Llc | Methods and compositions for treating pulmonary hypertension |
CN109182519B (zh) * | 2018-09-17 | 2019-06-14 | 中国人民解放军南京军区南京总医院 | 一种用于诊断acta2-mitf易位性血管周上皮样细胞肿瘤的探针组合及其应用 |
WO2020191053A1 (en) * | 2019-03-19 | 2020-09-24 | Abraxis Bioscience, Llc | Subcutaneous administration of nanoparticles comprising an mtor inhibitor and albumin for treatment of diseases |
KR20220106758A (ko) | 2019-10-28 | 2022-07-29 | 아브락시스 바이오사이언스, 엘엘씨 | 알부민 및 라파마이신의 제약 조성물 |
US20230000844A1 (en) * | 2019-11-11 | 2023-01-05 | Abraxis Bioscience, Llc | Biomarkers for nanoparticle compositions |
WO2021096997A1 (en) * | 2019-11-11 | 2021-05-20 | Abraxis Bioscience, Llc | Biomarkers for nanoparticle compositions |
CN116600789A (zh) * | 2020-06-19 | 2023-08-15 | 耶鲁大学 | 用于诱导耐受性的聚合胆汁酸酯纳米颗粒 |
Family Cites Families (85)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6528067B1 (en) | 1993-02-22 | 2003-03-04 | American Bioscience, Inc. | Total nutrient admixtures as stable multicomponent liquids or dry powders and methods for the preparation thereof |
US5439686A (en) | 1993-02-22 | 1995-08-08 | Vivorx Pharmaceuticals, Inc. | Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor |
US6749868B1 (en) | 1993-02-22 | 2004-06-15 | American Bioscience, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
US5362478A (en) | 1993-03-26 | 1994-11-08 | Vivorx Pharmaceuticals, Inc. | Magnetic resonance imaging with fluorocarbons encapsulated in a cross-linked polymeric shell |
US20030068362A1 (en) | 1993-02-22 | 2003-04-10 | American Bioscience, Inc. | Methods and formulations for the delivery of pharmacologically active agents |
US6753006B1 (en) | 1993-02-22 | 2004-06-22 | American Bioscience, Inc. | Paclitaxel-containing formulations |
US20070122465A1 (en) | 1993-02-22 | 2007-05-31 | Desai Neil P | Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
US5916596A (en) | 1993-02-22 | 1999-06-29 | Vivorx Pharmaceuticals, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
US6537579B1 (en) | 1993-02-22 | 2003-03-25 | American Bioscience, Inc. | Compositions and methods for administration of pharmacologically active compounds |
US6096331A (en) | 1993-02-22 | 2000-08-01 | Vivorx Pharmaceuticals, Inc. | Methods and compositions useful for administration of chemotherapeutic agents |
US5997904A (en) | 1993-02-22 | 1999-12-07 | American Bioscience, Inc. | Total nutrient admixtures as stable multicomponent liquids or dry powders and methods for the preparation thereof |
ES2219646T5 (es) | 1993-02-22 | 2008-11-01 | Abraxis Bioscience, Inc. | Metodos para la administracion in vivo de compuestos biologicos y composiciones utiles para los mismos. |
US5665383A (en) | 1993-02-22 | 1997-09-09 | Vivorx Pharmaceuticals, Inc. | Methods for the preparation of immunostimulating agents for in vivo delivery |
US5650156A (en) | 1993-02-22 | 1997-07-22 | Vivorx Pharmaceuticals, Inc. | Methods for in vivo delivery of nutriceuticals and compositions useful therefor |
US5665382A (en) | 1993-02-22 | 1997-09-09 | Vivorx Pharmaceuticals, Inc. | Methods for the preparation of pharmaceutically active agents for in vivo delivery |
US6565842B1 (en) | 1995-06-07 | 2003-05-20 | American Bioscience, Inc. | Crosslinkable polypeptide compositions |
US20070092563A1 (en) | 1996-10-01 | 2007-04-26 | Abraxis Bioscience, Inc. | Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
US8853260B2 (en) | 1997-06-27 | 2014-10-07 | Abraxis Bioscience, Llc | Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
JP4865937B2 (ja) | 1997-06-27 | 2012-02-01 | アブラクシス バイオサイエンス、エルエルシー | パクリタキセル製剤 |
US20030199425A1 (en) | 1997-06-27 | 2003-10-23 | Desai Neil P. | Compositions and methods for treatment of hyperplasia |
AU777528B2 (en) | 1999-04-22 | 2004-10-21 | Abraxis Bioscience, Llc | Long term administration of pharmacologically active agents |
WO2000071079A2 (en) | 1999-05-21 | 2000-11-30 | American Bioscience, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
ITMI20001107A1 (it) | 2000-05-18 | 2001-11-18 | Acs Dobfar Spa | Metodo per il trattamento di tumori solici mediante microparticelle di albumina incorporanti paclitaxel |
ITMI20020681A1 (it) | 2002-03-29 | 2003-09-29 | Acs Dobfar Spa | Procedimento per la produzione di nanoparticelle di paclitaxel ed albumina |
ITMI20020680A1 (it) | 2002-03-29 | 2003-09-29 | Acs Dobfar Spa | Composizione antitumorale migliorata a base di paclitaxel e metodo per il suo ottenimento |
US20050004002A1 (en) | 2002-12-09 | 2005-01-06 | American Bioscience, Inc. | Compositions and methods of delivery of pharmacological agents |
WO2004052401A2 (en) | 2002-12-09 | 2004-06-24 | American Bioscience, Inc. | Compositions and methods of delivery of pharmacological agents |
US20070166388A1 (en) | 2005-02-18 | 2007-07-19 | Desai Neil P | Combinations and modes of administration of therapeutic agents and combination therapy |
RU2452482C2 (ru) | 2005-02-18 | 2012-06-10 | АБРАКСИС БАЙОСАЙЕНС, ЭлЭлСи | Комбинация и способы введения терапевтических средств и комбинированной терапии |
US8735394B2 (en) | 2005-02-18 | 2014-05-27 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
TWI429452B (zh) | 2005-08-31 | 2014-03-11 | Abraxis Bioscience Llc | 包含弱水溶性藥劑及抗微生物劑之組合物 |
EP3527202A1 (en) | 2005-08-31 | 2019-08-21 | Abraxis BioScience, LLC | Compositions and methods for preparation of poorly water soluble drugs with increased stability |
MX2008012715A (es) | 2006-04-05 | 2008-10-14 | Novartis Ag | Combinaciones de agentes terapeuticos para el tratamiento de cancer. |
US20080280987A1 (en) | 2006-08-31 | 2008-11-13 | Desai Neil P | Methods of inhibiting angiogenesis and treating angiogenesis-associated diseases |
WO2008027055A1 (en) | 2006-08-31 | 2008-03-06 | Abraxis Bioscience, Llc | Methods of inhibiting angiogenesis and treating angiogenesis-associated diseases |
US20100112077A1 (en) | 2006-11-06 | 2010-05-06 | Abraxis Bioscience, Llc | Nanoparticles of paclitaxel and albumin in combination with bevacizumab against cancer |
AU2007334360B2 (en) | 2006-12-14 | 2013-10-17 | Abraxis Bioscience, Llc | Breast cancer therapy based on hormone receptor status with nanoparticles comprising taxane |
AU2013204187B2 (en) | 2007-03-07 | 2015-10-01 | Abraxis Bioscience, Llc | Nanoparticle comprising rapamycin and albumin as anticancer agent |
CN101730526A (zh) | 2007-03-07 | 2010-06-09 | 阿布拉科斯生物科学有限公司 | 作为抗癌剂的包含雷帕霉素和白蛋白的纳米颗粒 |
JP2010520289A (ja) | 2007-03-07 | 2010-06-10 | アブラクシス バイオサイエンス, エルエルシー | 抗癌剤としてラパマイシンおよびアルブミンを含むナノ粒子 |
WO2008137148A2 (en) | 2007-05-03 | 2008-11-13 | Abraxis Bioscience, Llc | Methods and compositions for treating pulmonary hypertension |
AU2008260447B2 (en) | 2007-06-01 | 2013-10-10 | Abraxis Bioscience, Llc | Methods and compositions for treating recurrent cancer |
KR20150136137A (ko) | 2008-04-10 | 2015-12-04 | 아브락시스 바이오사이언스, 엘엘씨 | 소수성 탁산 유도체의 조성물 및 그의 용도 |
CA2721153C (en) | 2008-04-10 | 2018-10-02 | Abraxis Bioscience, Llc | Compositions of hydrophobic taxane derivatives and uses thereof |
WO2010118365A1 (en) | 2009-04-10 | 2010-10-14 | Abraxis Bioscience, Llc | Nanoparticle formulations and uses therof |
ES2668837T3 (es) | 2008-12-11 | 2018-05-22 | Abraxis Bioscience, Llc | Terapia de combinación que incluye un taxano y un agente terapéutico adicional |
WO2010083298A1 (en) | 2009-01-14 | 2010-07-22 | Health Research Inc. | Methods and compositions containing mtor inhibitors for enhancing immune responses |
BRPI1008955A2 (pt) | 2009-03-13 | 2015-09-01 | Abraxis Bioscience Llc | Terapia de combinação com derivados de tiocolchicina. |
ME03596B (me) | 2009-04-15 | 2020-07-20 | Abraxis Bioscience Llc | Kompozicije nanočesтica bez priona i postupci povezani sa njima |
SG178873A1 (en) | 2009-08-25 | 2012-04-27 | Abraxis Bioscience Llc | Combination therapy with nanoparticle compositions of taxane and hedgehog inhibitors |
NZ602382A (en) | 2010-03-26 | 2014-11-28 | Abraxis Bioscience Llc | Methods of treatment of hepatocellular carcinoma |
US10660965B2 (en) | 2010-03-29 | 2020-05-26 | Abraxis Bioscience, Llc | Methods of enhancing drug delivery and effectiveness of therapeutic agents |
SI2552415T1 (sl) | 2010-03-29 | 2017-03-31 | Abraxis Bioscience, Llc | Metode za zdravljenje raka |
JP2013527232A (ja) | 2010-06-02 | 2013-06-27 | アブラクシス バイオサイエンス, エルエルシー | 膀胱がんの処置方法 |
SG186112A1 (en) | 2010-06-04 | 2013-01-30 | Abraxis Bioscience Llc | Methods of treatment of pancreatic cancer |
CA2801891C (en) | 2010-06-07 | 2020-10-27 | Abraxis Bioscience, Llc | Combination therapy methods for treating proliferative diseases |
SG194623A1 (en) | 2011-04-28 | 2013-12-30 | Abraxis Bioscience Llc | Intravascular delivery of nanoparticle compositions and uses thereof |
MX354859B (es) | 2011-12-14 | 2018-03-23 | Abraxis Bioscience Llc | Uso de excipientes polimericos para liofilizacion o congelacion de particulas. |
US9212224B2 (en) | 2012-05-15 | 2015-12-15 | Bristol-Myers Squibb Company | Antibodies that bind PD-L1 and uses thereof |
US9149455B2 (en) | 2012-11-09 | 2015-10-06 | Abraxis Bioscience, Llc | Methods of treating melanoma |
US20140186447A1 (en) | 2012-12-28 | 2014-07-03 | Abraxis Bioscience, Llc | Nanoparticle compositions of albumin and paclitaxel |
US9511046B2 (en) | 2013-01-11 | 2016-12-06 | Abraxis Bioscience, Llc | Methods of treating pancreatic cancer |
US20140199404A1 (en) | 2013-01-11 | 2014-07-17 | Abraxis Bioscience, Llc | Method for treating cancer based on level of a nucleoside transporter |
US20140199405A1 (en) | 2013-01-11 | 2014-07-17 | Abraxis Bioscience, Llc | Method for treating cancer based on mutation status of k-ras |
NZ630239A (en) | 2013-02-11 | 2017-08-25 | Abraxis Bioscience Llc | Methods of treating melanoma |
EP3698784A1 (en) | 2013-03-12 | 2020-08-26 | Abraxis BioScience, LLC | Methods of treating lung cancer |
EP2968253A4 (en) | 2013-03-13 | 2016-11-02 | Abraxis Bioscience Llc | METHODS OF TREATING PEDIATRIC SOLID TUMOR |
CN110934852A (zh) | 2013-03-14 | 2020-03-31 | 阿布拉科斯生物科学有限公司 | 治疗膀胱癌的方法 |
US20160015691A1 (en) | 2013-03-15 | 2016-01-21 | The Board Of Regents Of The University Of Texas System | Use of mtor inhibitors for prevention of neuroendocrine tumor development and growth |
JP6389241B2 (ja) | 2013-04-17 | 2018-09-12 | シグナル ファーマシューティカルズ,エルエルシー | 癌を治療するためのTORキナーゼ阻害剤及びIMiD化合物を含む組合せ療法 |
WO2015157120A1 (en) | 2014-04-06 | 2015-10-15 | Abraxis Bioscience, Llc | Combination therapy comprising nanoparticles of a taxane and albumin with abt-263 in methods for treating cancer |
US10705070B1 (en) | 2015-03-05 | 2020-07-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and poorly water soluble drug |
US20180064679A1 (en) | 2015-03-05 | 2018-03-08 | Abraxis Bioscience, Llc | Method for treating cancer based on level of glucocorticoid receptor |
US10527604B1 (en) | 2015-03-05 | 2020-01-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and paclitaxel |
CN107921050A (zh) | 2015-06-29 | 2018-04-17 | 阿布拉科斯生物科学有限公司 | 使用纳米颗粒mtor抑制剂联合疗法治疗血液学恶性肿瘤的方法 |
AU2016285727B9 (en) | 2015-06-29 | 2021-09-30 | Abraxis Bioscience, Llc | Biomarkers for nanoparticle compositions |
CN116585310A (zh) | 2015-06-29 | 2023-08-15 | 阿布拉科斯生物科学有限公司 | 治疗上皮样细胞肿瘤的方法 |
KR20180019229A (ko) | 2015-06-29 | 2018-02-23 | 아브락시스 바이오사이언스, 엘엘씨 | 나노입자 mTOR 억제제 조합 요법을 사용하여 고형 종양을 치료하는 방법 |
US20170181988A1 (en) | 2015-12-23 | 2017-06-29 | Cipla Limited | Methods for the treatment of bladder cancer |
US20190147986A1 (en) | 2016-05-17 | 2019-05-16 | Abraxis Bioscience, Llc | Methods for assessing neoadjuvant therapies |
KR102475256B1 (ko) | 2016-09-28 | 2022-12-08 | 아브락시스 바이오사이언스, 엘엘씨 | 미토콘드리아 및 대사 장애를 치료하는 방법 |
BR112019006329A2 (pt) | 2016-10-07 | 2019-06-25 | Abraxis Bioscience Llc | métodos de tratamento de câncer do trato biliar |
WO2018071399A1 (en) | 2016-10-10 | 2018-04-19 | Abraxis Bioscience, Llc | Nanoparticle formulations and methods of making and using thereof |
US20180374583A1 (en) | 2017-05-16 | 2018-12-27 | Abraxis Bioscience, Llc | Nomogram and survival predictions for pancreatic cancer |
CN111683657A (zh) | 2017-12-19 | 2020-09-18 | 阿布拉科斯生物科学有限公司 | 利用纳米颗粒mTOR抑制剂联合疗法治疗结肠癌的方法 |
-
2016
- 2016-06-29 CN CN202310469088.0A patent/CN116585310A/zh active Pending
- 2016-06-29 CN CN201680047512.0A patent/CN108024999A/zh active Pending
- 2016-06-29 PL PL16818717T patent/PL3313401T3/pl unknown
- 2016-06-29 ES ES16818717T patent/ES2897991T3/es active Active
- 2016-06-29 PT PT168187177T patent/PT3313401T/pt unknown
- 2016-06-29 EP EP21200495.6A patent/EP3998069A1/en active Pending
- 2016-06-29 EP EP16818717.7A patent/EP3313401B1/en active Active
- 2016-06-29 DK DK16818717.7T patent/DK3313401T3/da active
- 2016-06-29 AU AU2016285720A patent/AU2016285720C1/en active Active
- 2016-06-29 JP JP2017568129A patent/JP6987644B2/ja active Active
- 2016-06-29 WO PCT/US2016/040170 patent/WO2017004249A1/en active Application Filing
- 2016-06-29 SI SI201631392T patent/SI3313401T1/sl unknown
- 2016-06-29 EA EA202092187A patent/EA202092187A1/ru unknown
- 2016-06-29 EA EA201890157A patent/EA036790B1/ru not_active IP Right Cessation
- 2016-06-29 SG SG10202107198SA patent/SG10202107198SA/en unknown
- 2016-06-29 LT LTEPPCT/US2016/040170T patent/LT3313401T/lt unknown
- 2016-06-29 US US15/737,936 patent/US10973806B2/en active Active
- 2016-06-29 MX MX2017016322A patent/MX2017016322A/es unknown
- 2016-06-29 CA CA2990693A patent/CA2990693C/en active Active
- 2016-06-29 KR KR1020237040035A patent/KR20230165356A/ko not_active Application Discontinuation
- 2016-06-29 RS RS20211383A patent/RS62743B1/sr unknown
- 2016-06-29 BR BR112017027954-1A patent/BR112017027954B1/pt active IP Right Grant
- 2016-06-29 HU HUE16818717A patent/HUE057175T2/hu unknown
- 2016-06-29 CN CN202310468556.2A patent/CN116473964A/zh active Pending
- 2016-06-29 KR KR1020187002290A patent/KR102606071B1/ko active IP Right Grant
- 2016-06-29 HR HRP20211718TT patent/HRP20211718T1/hr unknown
-
2017
- 2017-12-12 IL IL256274A patent/IL256274B2/en unknown
- 2017-12-14 MX MX2021002455A patent/MX2021002455A/es unknown
- 2017-12-15 ZA ZA2017/08567A patent/ZA201708567B/en unknown
- 2017-12-28 CL CL2017003456A patent/CL2017003456A1/es unknown
-
2018
- 2018-05-21 HK HK18106583.0A patent/HK1247094A1/zh unknown
-
2021
- 2021-02-02 US US17/165,652 patent/US20210322391A1/en active Pending
- 2021-11-05 CY CY20211100959T patent/CY1124926T1/el unknown
- 2021-12-01 JP JP2021195392A patent/JP7351888B2/ja active Active
- 2021-12-13 AU AU2021286245A patent/AU2021286245B2/en active Active
-
2023
- 2023-09-14 JP JP2023149163A patent/JP2023175811A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2021002455A (es) | Metodos para tratar tumores de celulas epitelioides. | |
MX2015011753A (es) | Metodos para tratar cancer de vegija. | |
MX2018006217A (es) | Agonistas del receptor de apelina y metodos de uso. | |
MX2023013010A (es) | Composiciones con nanoparticulas que comprenden sirolimus y albumina para usarse en el tratamiento de cancer relacionado con una aberracion activante de m-tor. | |
MX2015008889A (es) | Metodo para tratar cancer con base en el estado de la mutacion k-ras. | |
MX2021002406A (es) | Composiciones farmaceuticas que comprenden un inhibidor de il-4r para usarse en el tratamiento de la esofagitis eosinofilica. | |
PH12017500660A1 (en) | Novel compositions, uses and methods for making them | |
MX2015008999A (es) | Inhibidores mk2 y usos de los mismos. | |
MY189454A (en) | 6-hydroxy-4-oxo-1,4-dihydropyrimidine-5-carboxamides as apj agonists | |
MX2015008888A (es) | Metodo para tratar el cancer basado en el nivel de un transportador de nucleosido. | |
MX2016006316A (es) | Inhibidores de mtor para potenciar la respuesta inmunitaria. | |
MX2018004344A (es) | 2,4-dihidroxi-nicotinamidas como agonistas del recepor de apelina (apj). | |
MX2020005213A (es) | Inhibidores de proteina cinasa 2 activada por proteina cinasa activada por mitogeno (mk2) y sus usos. | |
MX2018007155A (es) | Heteroarilhidroxipirimidinonas como agonistas del receptor de apelina (apj). | |
MX2015011783A (es) | Metodos para tratar tumores solidos pediatricos. | |
TR201900071T4 (tr) | Kontrollü Over Stimülasyonuna Yönelik Bileşim | |
MX2016009590A (es) | Composiciones de apilimod y métodos para usar las mismas. | |
MX2018000715A (es) | Metodos para tratar cancer usando apilimod. | |
PH12017501864A1 (en) | Compositions and methods for treating autism | |
MX2017013360A (es) | Métodos para tratar el cáncer. | |
PH12016500347A1 (en) | Triazolopyridine compounds, compositions and methods of use thereof | |
BR112015023383A2 (pt) | compostocomposição farmacêutica; e método de modulação | |
MX2017011116A (es) | Composiciones novedosas, usos y metodos para hacerlas. | |
MX2021008225A (es) | Composiciones y metodos para tratamiento de crecimiento celular anormal. | |
MX2017017119A (es) | Formulacion de alta concentracion. |