MX2017011116A - Composiciones novedosas, usos y metodos para hacerlas. - Google Patents

Composiciones novedosas, usos y metodos para hacerlas.

Info

Publication number
MX2017011116A
MX2017011116A MX2017011116A MX2017011116A MX2017011116A MX 2017011116 A MX2017011116 A MX 2017011116A MX 2017011116 A MX2017011116 A MX 2017011116A MX 2017011116 A MX2017011116 A MX 2017011116A MX 2017011116 A MX2017011116 A MX 2017011116A
Authority
MX
Mexico
Prior art keywords
methods
making
novel compositions
present
compounds
Prior art date
Application number
MX2017011116A
Other languages
English (en)
Inventor
Haddach Mustapha
Original Assignee
Pimera Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pimera Inc filed Critical Pimera Inc
Publication of MX2017011116A publication Critical patent/MX2017011116A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Generalmente, la invención actual proporciona compuestos de quinolona novedosos y la composición farmacéutica de los mismos que puede inhibir la proliferación celular e/o inducir la apoptosis celular. La invención actual también proporciona métodos para preparar tales compuestos y composiciones, y métodos para hacer y usar los mismos.
MX2017011116A 2015-03-04 2016-03-02 Composiciones novedosas, usos y metodos para hacerlas. MX2017011116A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562128208P 2015-03-04 2015-03-04
PCT/US2016/020418 WO2016141042A2 (en) 2015-03-04 2016-03-02 Novel compositions, uses and methods for making them

Publications (1)

Publication Number Publication Date
MX2017011116A true MX2017011116A (es) 2018-05-28

Family

ID=56848519

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017011116A MX2017011116A (es) 2015-03-04 2016-03-02 Composiciones novedosas, usos y metodos para hacerlas.

Country Status (8)

Country Link
US (9) US9758518B2 (es)
EP (1) EP3300501A4 (es)
JP (2) JP6878288B2 (es)
CN (1) CN107567448B (es)
CA (1) CA2978571C (es)
HK (1) HK1247927A1 (es)
MX (1) MX2017011116A (es)
WO (1) WO2016141042A2 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9758518B2 (en) 2015-03-04 2017-09-12 Pimera, Inc. Compositions, uses and methods for making them
CN106588920B (zh) * 2016-12-27 2018-10-30 云南大学 1,3-二氮杂环并[1,2-a]喹啉类化合物及其制备方法和抗肿瘤应用
WO2018183540A1 (en) 2017-03-28 2018-10-04 Pimera, Inc. Novel crystal forms of a pol1 inhibitor
WO2020160174A1 (en) * 2019-01-29 2020-08-06 Universita Degli Studi Di Padova Uses of compounds having anti-hsv-1 activity
US10947253B2 (en) 2019-08-05 2021-03-16 Ankh Life Sciences Limited Fused polycyclic dimers

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DE2929414A1 (de) 1979-07-20 1981-02-05 Hoechst Ag Pyrimido- eckige klammer auf 5',4' zu 5,6 eckige klammer zu -pyrido- eckige klammer auf 1,2-a eckige klammer zu -benzimidazole, verfahren zu ihrer herstellung und deren verwendung
DE3502689A1 (de) 1985-01-26 1986-07-31 Hoechst Ag, 6230 Frankfurt Elektrophotographisches aufzeichnungsmaterial
DE19509043A1 (de) 1995-03-03 1996-09-05 Bayer Ag Cyanierung von Doppelbindungssystemen
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EP1802306A2 (en) 2004-09-17 2007-07-04 Cylene Pharmaceuticals, Inc. Quinolone analog as cell proliferation inhibitors
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EP1874731A4 (en) 2005-04-15 2009-08-05 Cylene Pharmaceuticals Inc CHINOBENZOXAZINANALOGA AND METHOD FOR THE APPLICATION
WO2007019295A1 (en) 2005-08-05 2007-02-15 Cylene Pharmaceuticals, Inc. Methods of preparing quinolone analogs
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US8142909B2 (en) 2006-02-10 2012-03-27 Universal Display Corporation Blue phosphorescent imidazophenanthridine materials
JP2009535393A (ja) 2006-05-01 2009-10-01 ファイザー・プロダクツ・インク 置換２−アミノ縮合複素環式化合物
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US8124770B2 (en) 2009-04-01 2012-02-28 Beatriz Zayas Fluorescent cellular markers
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WO2018183540A1 (en) 2017-03-28 2018-10-04 Pimera, Inc. Novel crystal forms of a pol1 inhibitor

Also Published As

Publication number Publication date
US20190233422A1 (en) 2019-08-01
US20160257678A1 (en) 2016-09-08
US10590134B2 (en) 2020-03-17
CN107567448A (zh) 2018-01-09
EP3300501A2 (en) 2018-04-04
CN107567448B (zh) 2021-06-08
JP2021066741A (ja) 2021-04-30
HK1247927A1 (zh) 2018-10-05
US20210094952A1 (en) 2021-04-01
JP6878288B2 (ja) 2021-05-26
US20190389860A1 (en) 2019-12-26
WO2016141042A2 (en) 2016-09-09
US11618752B2 (en) 2023-04-04
EP3300501A4 (en) 2019-04-17
US20180079750A1 (en) 2018-03-22
WO2016141042A4 (en) 2016-12-15
US11866438B2 (en) 2024-01-09
US10975076B2 (en) 2021-04-13
WO2016141042A3 (en) 2016-11-03
JP2018507230A (ja) 2018-03-15
US9758518B2 (en) 2017-09-12
US11623928B2 (en) 2023-04-11
US10442801B2 (en) 2019-10-15
CA2978571A1 (en) 2016-09-09
US20170334905A1 (en) 2017-11-23
US9951066B2 (en) 2018-04-24
US20200361937A1 (en) 2020-11-19
US20180291020A1 (en) 2018-10-11
CA2978571C (en) 2023-10-03
US20210317120A1 (en) 2021-10-14
US10745403B2 (en) 2020-08-18

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