HK1247927A1 - 新型組合物、用途及其製備方法 - Google Patents
新型組合物、用途及其製備方法Info
- Publication number
- HK1247927A1 HK1247927A1 HK18107441.0A HK18107441A HK1247927A1 HK 1247927 A1 HK1247927 A1 HK 1247927A1 HK 18107441 A HK18107441 A HK 18107441A HK 1247927 A1 HK1247927 A1 HK 1247927A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- making
- methods
- novel compositions
- compositions
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562128208P | 2015-03-04 | 2015-03-04 | |
PCT/US2016/020418 WO2016141042A2 (en) | 2015-03-04 | 2016-03-02 | Novel compositions, uses and methods for making them |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1247927A1 true HK1247927A1 (zh) | 2018-10-05 |
Family
ID=56848519
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18107441.0A HK1247927A1 (zh) | 2015-03-04 | 2018-06-07 | 新型組合物、用途及其製備方法 |
Country Status (8)
Country | Link |
---|---|
US (9) | US9758518B2 (zh) |
EP (1) | EP3300501A4 (zh) |
JP (2) | JP6878288B2 (zh) |
CN (1) | CN107567448B (zh) |
CA (1) | CA2978571C (zh) |
HK (1) | HK1247927A1 (zh) |
MX (1) | MX2017011116A (zh) |
WO (1) | WO2016141042A2 (zh) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9758518B2 (en) | 2015-03-04 | 2017-09-12 | Pimera, Inc. | Compositions, uses and methods for making them |
CN106588920B (zh) * | 2016-12-27 | 2018-10-30 | 云南大学 | 1,3-二氮杂环并[1,2-a]喹啉类化合物及其制备方法和抗肿瘤应用 |
CN115583948A (zh) * | 2017-03-28 | 2023-01-10 | 皮梅拉股份有限公司 | Pol1抑制剂的新型晶体形式 |
US20220105083A1 (en) * | 2019-01-29 | 2022-04-07 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Uses of compounds having anti-hsv-1 activity |
US10947253B2 (en) | 2019-08-05 | 2021-03-16 | Ankh Life Sciences Limited | Fused polycyclic dimers |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
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US1042801A (en) | 1909-10-28 | 1912-10-29 | Isidor Kitsee | Protecting kinematographic films. |
NL7709746A (nl) | 1976-09-09 | 1978-03-13 | Hoechst Ag | Werkwijze ter bereiding van benzimidazo-(1,2-a)-chi- nolinen. |
DE2929414A1 (de) | 1979-07-20 | 1981-02-05 | Hoechst Ag | Pyrimido- eckige klammer auf 5',4' zu 5,6 eckige klammer zu -pyrido- eckige klammer auf 1,2-a eckige klammer zu -benzimidazole, verfahren zu ihrer herstellung und deren verwendung |
DE3502689A1 (de) | 1985-01-26 | 1986-07-31 | Hoechst Ag, 6230 Frankfurt | Elektrophotographisches aufzeichnungsmaterial |
DE19509043A1 (de) | 1995-03-03 | 1996-09-05 | Bayer Ag | Cyanierung von Doppelbindungssystemen |
US5624677A (en) | 1995-06-13 | 1997-04-29 | Pentech Pharmaceuticals, Inc. | Controlled release of drugs delivered by sublingual or buccal administration |
ES2260300T3 (es) * | 2000-10-03 | 2006-11-01 | Bristol-Myers Squibb Company | Compuestos tetraciclicos sustituidos con amino utiles como agentes antiinflamatorios y composiciones farmaceuticas que comprenden los mismos. |
NZ543006A (en) | 2003-04-07 | 2009-03-31 | Cylene Pharmaceuticals Inc | Substituted quinobenzoxazine analogs |
US7507727B2 (en) | 2003-04-07 | 2009-03-24 | Cylene Pharmaceuticals, Inc. | Substituted quinobenzoxazine analogs and methods of using thereof |
US7354916B2 (en) | 2003-04-07 | 2008-04-08 | Cylene Pharmaceuticals | Substituted quinobenzoxazine analogs |
US7652134B2 (en) | 2004-09-17 | 2010-01-26 | Cylene Pharmaceuticals, Inc. | Methods for converting quinolone esters into quinolone amides |
JP2008513485A (ja) | 2004-09-17 | 2008-05-01 | サイリーン ファーマシューティカルズ インコーポレーティッド | キノロンアナログ |
CA2604787A1 (en) | 2005-04-15 | 2006-10-26 | Cylene Pharmaceuticals, Inc. | Quinobenzoxazine analogs and methods of using thereof |
US7816524B2 (en) | 2005-08-05 | 2010-10-19 | Cylene Pharmaceuticals, Inc. | Methods of preparing quinolone analogs |
US20070149506A1 (en) | 2005-09-22 | 2007-06-28 | Arvanitis Argyrios G | Azepine inhibitors of Janus kinases |
US8142909B2 (en) | 2006-02-10 | 2012-03-27 | Universal Display Corporation | Blue phosphorescent imidazophenanthridine materials |
US7998978B2 (en) | 2006-05-01 | 2011-08-16 | Pfizer Inc. | Substituted 2-amino-fused heterocyclic compounds |
WO2008060693A2 (en) | 2006-05-17 | 2008-05-22 | Cylene Pharmaceuticals, Inc. | Tetracyclic imidazole analogs |
PL3092901T3 (pl) * | 2007-10-05 | 2020-10-19 | Senhwa Biosciences, Inc. | Analogi chinolonu i sposoby z nimi związane |
CA2731368C (en) | 2008-08-06 | 2013-05-14 | Pfizer Inc. | 6 substituted 2-heterocyclylamino pyrazine compounds as chk-1 inhibitors |
CN102119158B (zh) | 2008-11-03 | 2015-09-09 | 株式会社Lg化学 | 含氮杂环化合物及使用该化合物的有机电子器件 |
US8124770B2 (en) | 2009-04-01 | 2012-02-28 | Beatriz Zayas | Fluorescent cellular markers |
CN101781312B (zh) | 2009-12-30 | 2012-09-26 | 中国科学院广州生物医药与健康研究院 | 一种吲哚衍生物的合成方法 |
US8637529B2 (en) | 2010-06-11 | 2014-01-28 | AbbYie Inc. | Pyrazolo[3,4-d]pyrimidine compounds |
KR101567610B1 (ko) | 2010-11-04 | 2015-11-09 | 주식회사 엘지화학 | 신규한 질소 함유 헤테로환 화합물 및 이를 이용한 유기 전자 소자 |
EA201490610A1 (ru) | 2011-10-21 | 2014-09-30 | ГЛАКСОСМИТКЛАЙН ЭлЭлСи | Соединения и способы усиления врожденных иммунных ответов |
KR101561730B1 (ko) | 2012-02-06 | 2015-10-22 | 주식회사 엘지화학 | 질소원소를 함유한 헤테로고리 유도체 및 이를 이용한 유기 전자 소자 |
ES2754207T3 (es) | 2013-11-28 | 2020-04-16 | Tel Hashomer Medical Res Infrastructure & Services Ltd | Inhibidores de la ARN polimerasa I y usos de los mismos |
US9758518B2 (en) | 2015-03-04 | 2017-09-12 | Pimera, Inc. | Compositions, uses and methods for making them |
PL3140305T3 (pl) | 2014-05-09 | 2018-10-31 | Pimera, Inc. | Nowe kompozycje, ich zastosowania i sposoby wytwarzania |
CN106349244B (zh) | 2015-07-13 | 2018-07-27 | 首都医科大学 | 苯并咪唑并喹唑啉二甲氧苯氧乙酰-AA-OBzl,其合成,活性和应用 |
WO2017087235A1 (en) | 2015-11-20 | 2017-05-26 | Senhwa Biosciences, Inc. | Combination therapy of tetracyclic quinolone analogs for treating cancer |
CN115583948A (zh) | 2017-03-28 | 2023-01-10 | 皮梅拉股份有限公司 | Pol1抑制剂的新型晶体形式 |
-
2015
- 2015-11-06 US US14/935,155 patent/US9758518B2/en active Active
-
2016
- 2016-03-02 CA CA2978571A patent/CA2978571C/en active Active
- 2016-03-02 US US15/555,024 patent/US10975076B2/en active Active
- 2016-03-02 EP EP16759401.9A patent/EP3300501A4/en active Pending
- 2016-03-02 JP JP2017546121A patent/JP6878288B2/ja active Active
- 2016-03-02 CN CN201680022357.7A patent/CN107567448B/zh active Active
- 2016-03-02 MX MX2017011116A patent/MX2017011116A/es unknown
- 2016-03-02 WO PCT/US2016/020418 patent/WO2016141042A2/en active Application Filing
-
2017
- 2017-04-11 US US15/485,106 patent/US9951066B2/en active Active
- 2017-07-27 US US15/661,770 patent/US10590134B2/en active Active
-
2018
- 2018-01-08 US US15/864,965 patent/US10442801B2/en active Active
- 2018-06-07 HK HK18107441.0A patent/HK1247927A1/zh unknown
-
2019
- 2019-06-03 US US16/430,129 patent/US10745403B2/en active Active
-
2020
- 2020-01-10 US US16/739,354 patent/US11618752B2/en active Active
- 2020-07-09 US US16/925,220 patent/US11623928B2/en active Active
-
2021
- 2021-02-02 JP JP2021014802A patent/JP2021066741A/ja active Pending
- 2021-03-17 US US17/204,459 patent/US11866438B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20210094952A1 (en) | 2021-04-01 |
WO2016141042A3 (en) | 2016-11-03 |
US10975076B2 (en) | 2021-04-13 |
US20200361937A1 (en) | 2020-11-19 |
US20190233422A1 (en) | 2019-08-01 |
WO2016141042A4 (en) | 2016-12-15 |
US10590134B2 (en) | 2020-03-17 |
US10745403B2 (en) | 2020-08-18 |
JP2021066741A (ja) | 2021-04-30 |
US10442801B2 (en) | 2019-10-15 |
US11866438B2 (en) | 2024-01-09 |
CN107567448A (zh) | 2018-01-09 |
CA2978571C (en) | 2023-10-03 |
US20190389860A1 (en) | 2019-12-26 |
WO2016141042A2 (en) | 2016-09-09 |
US9951066B2 (en) | 2018-04-24 |
US20170334905A1 (en) | 2017-11-23 |
JP2018507230A (ja) | 2018-03-15 |
US11618752B2 (en) | 2023-04-04 |
US20180291020A1 (en) | 2018-10-11 |
CN107567448B (zh) | 2021-06-08 |
EP3300501A2 (en) | 2018-04-04 |
JP6878288B2 (ja) | 2021-05-26 |
CA2978571A1 (en) | 2016-09-09 |
US9758518B2 (en) | 2017-09-12 |
US20180079750A1 (en) | 2018-03-22 |
MX2017011116A (es) | 2018-05-28 |
EP3300501A4 (en) | 2019-04-17 |
US11623928B2 (en) | 2023-04-11 |
US20160257678A1 (en) | 2016-09-08 |
US20210317120A1 (en) | 2021-10-14 |
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