HK1247927A1 - 新型組合物、用途及其製備方法 - Google Patents

新型組合物、用途及其製備方法

Info

Publication number
HK1247927A1
HK1247927A1 HK18107441.0A HK18107441A HK1247927A1 HK 1247927 A1 HK1247927 A1 HK 1247927A1 HK 18107441 A HK18107441 A HK 18107441A HK 1247927 A1 HK1247927 A1 HK 1247927A1
Authority
HK
Hong Kong
Prior art keywords
making
methods
novel compositions
compositions
novel
Prior art date
Application number
HK18107441.0A
Other languages
English (en)
Inventor
M‧哈達徹
Original Assignee
皮梅拉股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 皮梅拉股份有限公司 filed Critical 皮梅拉股份有限公司
Publication of HK1247927A1 publication Critical patent/HK1247927A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK18107441.0A 2015-03-04 2018-06-07 新型組合物、用途及其製備方法 HK1247927A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562128208P 2015-03-04 2015-03-04
PCT/US2016/020418 WO2016141042A2 (en) 2015-03-04 2016-03-02 Novel compositions, uses and methods for making them

Publications (1)

Publication Number Publication Date
HK1247927A1 true HK1247927A1 (zh) 2018-10-05

Family

ID=56848519

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18107441.0A HK1247927A1 (zh) 2015-03-04 2018-06-07 新型組合物、用途及其製備方法

Country Status (8)

Country Link
US (9) US9758518B2 (zh)
EP (1) EP3300501A4 (zh)
JP (2) JP6878288B2 (zh)
CN (1) CN107567448B (zh)
CA (1) CA2978571C (zh)
HK (1) HK1247927A1 (zh)
MX (1) MX2017011116A (zh)
WO (1) WO2016141042A2 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9758518B2 (en) 2015-03-04 2017-09-12 Pimera, Inc. Compositions, uses and methods for making them
CN106588920B (zh) * 2016-12-27 2018-10-30 云南大学 1,3-二氮杂环并[1,2-a]喹啉类化合物及其制备方法和抗肿瘤应用
CN115583948A (zh) 2017-03-28 2023-01-10 皮梅拉股份有限公司 Pol1抑制剂的新型晶体形式
WO2020160174A1 (en) * 2019-01-29 2020-08-06 Universita Degli Studi Di Padova Uses of compounds having anti-hsv-1 activity
US10947253B2 (en) 2019-08-05 2021-03-16 Ankh Life Sciences Limited Fused polycyclic dimers

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NL7709746A (nl) 1976-09-09 1978-03-13 Hoechst Ag Werkwijze ter bereiding van benzimidazo-(1,2-a)-chi- nolinen.
DE2929414A1 (de) 1979-07-20 1981-02-05 Hoechst Ag Pyrimido- eckige klammer auf 5',4' zu 5,6 eckige klammer zu -pyrido- eckige klammer auf 1,2-a eckige klammer zu -benzimidazole, verfahren zu ihrer herstellung und deren verwendung
DE3502689A1 (de) 1985-01-26 1986-07-31 Hoechst Ag, 6230 Frankfurt Elektrophotographisches aufzeichnungsmaterial
DE19509043A1 (de) 1995-03-03 1996-09-05 Bayer Ag Cyanierung von Doppelbindungssystemen
US5624677A (en) 1995-06-13 1997-04-29 Pentech Pharmaceuticals, Inc. Controlled release of drugs delivered by sublingual or buccal administration
HUP0302925A3 (en) * 2000-10-03 2004-10-28 Bristol Myers Squibb Co Amino-substituted tetracyclic compouds useful as anti-inflammatory agents and pharmaceutical compositions comprising same
US7507727B2 (en) 2003-04-07 2009-03-24 Cylene Pharmaceuticals, Inc. Substituted quinobenzoxazine analogs and methods of using thereof
US7354916B2 (en) 2003-04-07 2008-04-08 Cylene Pharmaceuticals Substituted quinobenzoxazine analogs
KR100944600B1 (ko) 2003-04-07 2010-02-25 사일린 파마슈티칼스, 인크 치환된 퀴노벤족사진 유사체
US7816406B2 (en) 2004-09-17 2010-10-19 Cylene Pharmaceuticals, Inc. Quinolone analogs
US7652134B2 (en) 2004-09-17 2010-01-26 Cylene Pharmaceuticals, Inc. Methods for converting quinolone esters into quinolone amides
WO2006113509A2 (en) 2005-04-15 2006-10-26 Cylene Pharmaceuticals, Inc. Quinobenzoxazine analogs and methods of using thereof
PL1928887T3 (pl) 2005-08-05 2015-05-29 Senhwa Biosciences Inc Sposoby otrzymywania analogów chinolonowych
EP1926735A1 (en) 2005-09-22 2008-06-04 Incyte Corporation Tetracyclic inhibitors of janus kinases
EP2024342A2 (en) 2006-05-01 2009-02-18 Pfizer Products Incorporated Substituted 2-amino-fused heterocyclic compounds
WO2008060693A2 (en) 2006-05-17 2008-05-22 Cylene Pharmaceuticals, Inc. Tetracyclic imidazole analogs
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US8518952B2 (en) 2008-08-06 2013-08-27 Pfizer Inc. 6 substituted 2-heterocyclylamino pyrazine compounds as CHK-1 inhibitors
JP5801193B2 (ja) 2008-11-03 2015-10-28 エルジー・ケム・リミテッド 新しい含窒素複素環化合物およびそれを用いた有機電子素子
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WO2011156698A2 (en) 2010-06-11 2011-12-15 Abbott Laboratories NOVEL PYRAZOLO[3,4-d]PYRIMIDINE COMPOUNDS
KR101567610B1 (ko) 2010-11-04 2015-11-09 주식회사 엘지화학 신규한 질소 함유 헤테로환 화합물 및 이를 이용한 유기 전자 소자
CN103957910A (zh) 2011-10-21 2014-07-30 葛兰素史克有限责任公司 增加先天免疫反应的化合物和方法
KR101561730B1 (ko) 2012-02-06 2015-10-22 주식회사 엘지화학 질소원소를 함유한 헤테로고리 유도체 및 이를 이용한 유기 전자 소자
ES2754207T3 (es) 2013-11-28 2020-04-16 Tel Hashomer Medical Res Infrastructure & Services Ltd Inhibidores de la ARN polimerasa I y usos de los mismos
TR201809990T4 (en) 2014-05-09 2018-08-27 Pimera Inc NEW COMPOSITIONS, USES AND METHODS FOR THEIR MAKING.
US9758518B2 (en) 2015-03-04 2017-09-12 Pimera, Inc. Compositions, uses and methods for making them
CN106349244B (zh) 2015-07-13 2018-07-27 首都医科大学 苯并咪唑并喹唑啉二甲氧苯氧乙酰-AA-OBzl,其合成,活性和应用
CA3005730A1 (en) 2015-11-20 2017-05-26 Senhwa Biosciences, Inc. Combination therapy of tetracyclic quinolone analogs for treating cancer
CN115583948A (zh) 2017-03-28 2023-01-10 皮梅拉股份有限公司 Pol1抑制剂的新型晶体形式

Also Published As

Publication number Publication date
WO2016141042A2 (en) 2016-09-09
US11623928B2 (en) 2023-04-11
JP2018507230A (ja) 2018-03-15
MX2017011116A (es) 2018-05-28
WO2016141042A4 (en) 2016-12-15
EP3300501A2 (en) 2018-04-04
US20180291020A1 (en) 2018-10-11
US20180079750A1 (en) 2018-03-22
CA2978571A1 (en) 2016-09-09
US20160257678A1 (en) 2016-09-08
CA2978571C (en) 2023-10-03
EP3300501A4 (en) 2019-04-17
US9758518B2 (en) 2017-09-12
US11866438B2 (en) 2024-01-09
US10442801B2 (en) 2019-10-15
US9951066B2 (en) 2018-04-24
US20190389860A1 (en) 2019-12-26
CN107567448B (zh) 2021-06-08
CN107567448A (zh) 2018-01-09
US20170334905A1 (en) 2017-11-23
US20200361937A1 (en) 2020-11-19
US20210094952A1 (en) 2021-04-01
JP2021066741A (ja) 2021-04-30
US11618752B2 (en) 2023-04-04
US20210317120A1 (en) 2021-10-14
US10975076B2 (en) 2021-04-13
US20190233422A1 (en) 2019-08-01
US10745403B2 (en) 2020-08-18
WO2016141042A3 (en) 2016-11-03
JP6878288B2 (ja) 2021-05-26
US10590134B2 (en) 2020-03-17

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