MX2014007623A - Produccion mejorada de isopreno con el uso de celulas hospederas que tienen actividad de ispa reducida. - Google Patents
Produccion mejorada de isopreno con el uso de celulas hospederas que tienen actividad de ispa reducida.Info
- Publication number
- MX2014007623A MX2014007623A MX2014007623A MX2014007623A MX2014007623A MX 2014007623 A MX2014007623 A MX 2014007623A MX 2014007623 A MX2014007623 A MX 2014007623A MX 2014007623 A MX2014007623 A MX 2014007623A MX 2014007623 A MX2014007623 A MX 2014007623A
- Authority
- MX
- Mexico
- Prior art keywords
- isoprene
- host cells
- enhanced production
- production
- decreased
- Prior art date
Links
- RRHGJUQNOFWUDK-UHFFFAOYSA-N Isoprene Chemical compound CC(=C)C=C RRHGJUQNOFWUDK-UHFFFAOYSA-N 0.000 title abstract 10
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 230000003247 decreasing effect Effects 0.000 title abstract 2
- 230000000694 effects Effects 0.000 title 1
- 244000005700 microbiome Species 0.000 abstract 3
- 230000005714 functional activity Effects 0.000 abstract 2
- 101150064873 ispA gene Proteins 0.000 abstract 2
- 150000003505 terpenes Chemical class 0.000 abstract 2
- 238000009825 accumulation Methods 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
- C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
- C12Y205/01001—Dimethylallyltranstransferase (2.5.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
- C12Y402/03027—Isoprene synthase (4.2.3.27)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161580163P | 2011-12-23 | 2011-12-23 | |
| US201261639855P | 2012-04-27 | 2012-04-27 | |
| PCT/US2012/071518 WO2013096925A1 (en) | 2011-12-23 | 2012-12-21 | Enhanced production of isoprene using host cells having decreased ispa activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2014007623A true MX2014007623A (es) | 2015-02-04 |
Family
ID=47522963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014007623A MX2014007623A (es) | 2011-12-23 | 2012-12-21 | Produccion mejorada de isopreno con el uso de celulas hospederas que tienen actividad de ispa reducida. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8975051B2 (enExample) |
| EP (1) | EP2794863A1 (enExample) |
| JP (1) | JP2015510392A (enExample) |
| CN (1) | CN104245927A (enExample) |
| AU (1) | AU2012358149A1 (enExample) |
| BR (1) | BR112014014947A2 (enExample) |
| CA (1) | CA2859885A1 (enExample) |
| MX (1) | MX2014007623A (enExample) |
| SG (1) | SG11201403163QA (enExample) |
| WO (1) | WO2013096925A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
| CA2880962C (en) * | 2012-08-17 | 2019-07-30 | Evolva Sa | Increased production of terpenes and terpenoids |
| WO2015083769A1 (ja) * | 2013-12-04 | 2015-06-11 | 国立研究開発法人理化学研究所 | 光合成のみによるポリヒドロキシアルカン酸の生産 |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| JP2018014960A (ja) * | 2016-07-29 | 2018-02-01 | 横浜ゴム株式会社 | 発現ベクター、形質転換された藻類、形質転換された珪藻、及び、ポリヌクレオチド |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| WO2018208116A1 (ko) * | 2017-05-11 | 2018-11-15 | 경상대학교산학협력단 | 형질전환 생물체 선별용 마커 조성물, 형질전환 생물체 및 형질전환 방법 |
| EP3623480A4 (en) | 2017-05-11 | 2021-02-24 | Industry-Academic Cooperation Foundation Gyeongsang National University | COMPOSITION OF MARKER FOR SELECTING A LIVING MODIFIED ORGANISM, LIVING MODIFIED ORGANISM AND PROCESS OF TRANSFORMATION |
| CN110317765B (zh) * | 2018-03-29 | 2020-11-20 | 中国科学院天津工业生物技术研究所 | 一种高产香叶醇葡萄糖苷的大肠杆菌表达菌株及其应用 |
| CN113366009B (zh) * | 2018-11-27 | 2025-02-11 | 科纳科学控股有限公司 | 用于生物合成大麻素的双向多酶支架 |
| US12351850B2 (en) * | 2020-04-30 | 2025-07-08 | Sutro Biopharma, Inc. | Methods of producing full-length antibodies using E. coli |
| CN112553134B (zh) * | 2020-12-30 | 2022-09-06 | 江南大学 | 一种在枯草芽孢杆菌中表达α-淀粉酶的方法 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19629568C1 (de) | 1996-07-15 | 1998-01-08 | Fraunhofer Ges Forschung | Verfahren zur Herstellung von Isopren |
| US20050287655A1 (en) | 2002-05-10 | 2005-12-29 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing mevalonic acid |
| AU2003287028B2 (en) | 2002-10-04 | 2008-09-04 | E.I. Du Pont De Nemours And Company | Process for the biological production of 1,3-propanediol with high yield |
| RU2004124226A (ru) | 2004-08-10 | 2006-01-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | Использование фосфокетолазы для продукции полезных метаболитов |
| CA2651747C (en) * | 2006-05-26 | 2017-10-24 | Amyris Biotechnologies, Inc. | Production of isoprenoids |
| US7947478B2 (en) | 2006-06-29 | 2011-05-24 | The Regents Of The University Of California | Short chain volatile hydrocarbon production using genetically engineered microalgae, cyanobacteria or bacteria |
| JP4986547B2 (ja) | 2006-09-04 | 2012-07-25 | 株式会社Ａｄｅｋａ | 新規なアセトアセチルＣｏＡ合成酵素、それをコードするＤＮＡ配列、当該酵素の製造方法および当該酵素を利用したメバロン酸の製造方法 |
| BRPI0823506A8 (pt) | 2007-12-13 | 2018-05-15 | Danisco Us Inc Genencor Div | composições e métodos para a produção de isoprene |
| WO2009100231A2 (en) | 2008-02-06 | 2009-08-13 | The Regents Of The University Of California | Short chain volatile isoprene hydrocarbon production using the mevalonic acid pathway in genetically engineered yeast and fungi |
| JP2011518564A (ja) | 2008-04-23 | 2011-06-30 | ダニスコ・ユーエス・インク | 改良された微生物によるイソプレン産出用のイソプレンシンターゼ変異体 |
| US7632995B2 (en) | 2008-05-09 | 2009-12-15 | Monsanto Technology Llc | Plants and seeds of hybrid corn variety CH852179 |
| EP2310490B1 (en) | 2008-07-02 | 2019-01-02 | Danisco US Inc. | Methods for producing isoprene |
| BRPI0918936A2 (pt) | 2008-09-15 | 2019-09-24 | Danisco Us Inc | conversão de derivados de prenila em isopreno |
| MY156562A (en) | 2008-09-15 | 2016-02-26 | Danisco Us Inc | Increased isoprene production using the archaeal lower mevalonate pathway |
| CA2737223A1 (en) | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Reduction of carbon dioxide emission during isoprene production by fermentation |
| WO2010031079A1 (en) | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Systems using cell culture for production of isoprene |
| CN102333866B (zh) | 2008-12-30 | 2015-04-29 | 丹尼斯科美国公司 | 生产异戊二烯和共同产物的方法 |
| US20100297749A1 (en) | 2009-04-21 | 2010-11-25 | Sapphire Energy, Inc. | Methods and systems for biofuel production |
| EP2421966A2 (en) | 2009-04-23 | 2012-02-29 | Danisco US Inc. | Three-dimensional structure of isoprene synthase and its use thereof for generating variants |
| JP4760951B2 (ja) | 2009-05-08 | 2011-08-31 | トヨタ自動車株式会社 | ブタノール生産能を有する組換え微生物及びブタノールの製造方法 |
| TW201412988A (zh) | 2009-06-17 | 2014-04-01 | Danisco Us Inc | 使用ｄｘｐ及ｍｖａ途徑之改良之異戊二烯製造 |
| TWI434921B (zh) | 2009-06-17 | 2014-04-21 | Danisco Us Inc | 從生物異戊二烯組合物製造燃料成分之方法及系統 |
| CA2773675A1 (en) | 2009-09-15 | 2011-03-24 | Sapphire Energy, Inc. | A system for transformation of the chloroplast genome of scenedesmus sp. and dunaliella sp. |
| CN102884028B (zh) | 2009-12-18 | 2015-08-19 | 丹尼斯科美国公司 | 从可再生资源中纯化异戊二烯 |
| AU2010336342B2 (en) * | 2009-12-23 | 2015-02-26 | Danisco Us Inc. | Compositions and methods for the increased production of isoprene and other products with 6 - phosphogluconolactonase (PGL) |
| US8871488B2 (en) | 2010-06-18 | 2014-10-28 | Butamax Advanced Biofuels Llc | Recombinant host cells comprising phosphoketolases |
| JP2014502148A (ja) | 2010-10-27 | 2014-01-30 | ダニスコ・ユーエス・インク | イソプレン生産の向上を目的としたイソプレン合成酵素変異体 |
-
2012
- 2012-12-21 US US13/725,929 patent/US8975051B2/en not_active Expired - Fee Related
- 2012-12-21 CN CN201280070444.1A patent/CN104245927A/zh active Pending
- 2012-12-21 MX MX2014007623A patent/MX2014007623A/es unknown
- 2012-12-21 SG SG11201403163QA patent/SG11201403163QA/en unknown
- 2012-12-21 CA CA2859885A patent/CA2859885A1/en not_active Abandoned
- 2012-12-21 BR BR112014014947-0A patent/BR112014014947A2/pt not_active Application Discontinuation
- 2012-12-21 EP EP12813234.7A patent/EP2794863A1/en not_active Withdrawn
- 2012-12-21 JP JP2014548993A patent/JP2015510392A/ja active Pending
- 2012-12-21 WO PCT/US2012/071518 patent/WO2013096925A1/en not_active Ceased
- 2012-12-21 AU AU2012358149A patent/AU2012358149A1/en not_active Abandoned
-
2015
- 2015-01-09 US US14/593,860 patent/US9388431B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| SG11201403163QA (en) | 2014-09-26 |
| CA2859885A1 (en) | 2013-06-27 |
| EP2794863A1 (en) | 2014-10-29 |
| US9388431B2 (en) | 2016-07-12 |
| US20130164808A1 (en) | 2013-06-27 |
| JP2015510392A (ja) | 2015-04-09 |
| US8975051B2 (en) | 2015-03-10 |
| CN104245927A (zh) | 2014-12-24 |
| US20150218590A1 (en) | 2015-08-06 |
| AU2012358149A1 (en) | 2014-07-03 |
| WO2013096925A1 (en) | 2013-06-27 |
| BR112014014947A2 (pt) | 2020-10-27 |
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