JP2015510392A - 低減したispa活性を有する宿主細胞を用いるイソプレン産生増強法 - Google Patents

低減したispa活性を有する宿主細胞を用いるイソプレン産生増強法 Download PDF

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JP2015510392A
JP2015510392A JP2014548993A JP2014548993A JP2015510392A JP 2015510392 A JP2015510392 A JP 2015510392A JP 2014548993 A JP2014548993 A JP 2014548993A JP 2014548993 A JP2014548993 A JP 2014548993A JP 2015510392 A JP2015510392 A JP 2015510392A
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polypeptide
cell
ispa
isoprene
nucleic acids
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JP2015510392A5 (enExample
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マコーリフ、ジョセフ・シー
ミューア、レイチェル・イー
ニールセン、アレックス・ティー
ペレス、キャロライン・エム
ヴァヴィリン、ドミトリ・ブイ
ウェルス、デレック・エイチ
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Goodyear Tire and Rubber Co
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Goodyear Tire and Rubber Co
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1085Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y205/00Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/01001Dimethylallyltranstransferase (2.5.1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/03Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03027Isoprene synthase (4.2.3.27)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Chemical & Material Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
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  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
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  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2014548993A 2011-12-23 2012-12-21 低減したispa活性を有する宿主細胞を用いるイソプレン産生増強法 Pending JP2015510392A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161580163P 2011-12-23 2011-12-23
US61/580,163 2011-12-23
US201261639855P 2012-04-27 2012-04-27
US61/639,855 2012-04-27
PCT/US2012/071518 WO2013096925A1 (en) 2011-12-23 2012-12-21 Enhanced production of isoprene using host cells having decreased ispa activity

Publications (2)

Publication Number Publication Date
JP2015510392A true JP2015510392A (ja) 2015-04-09
JP2015510392A5 JP2015510392A5 (enExample) 2016-02-12

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JP2014548993A Pending JP2015510392A (ja) 2011-12-23 2012-12-21 低減したispa活性を有する宿主細胞を用いるイソプレン産生増強法

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Country Link
US (2) US8975051B2 (enExample)
EP (1) EP2794863A1 (enExample)
JP (1) JP2015510392A (enExample)
CN (1) CN104245927A (enExample)
AU (1) AU2012358149A1 (enExample)
BR (1) BR112014014947A2 (enExample)
CA (1) CA2859885A1 (enExample)
MX (1) MX2014007623A (enExample)
SG (1) SG11201403163QA (enExample)
WO (1) WO2013096925A1 (enExample)

Cited By (2)

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JP2018014960A (ja) * 2016-07-29 2018-02-01 横浜ゴム株式会社 発現ベクター、形質転換された藻類、形質転換された珪藻、及び、ポリヌクレオチド
JP2023524097A (ja) * 2020-04-30 2023-06-08 ストロ バイオファーマ, インコーポレイテッド 大腸菌を用いた全長抗体の作製方法

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US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
CA2880962C (en) * 2012-08-17 2019-07-30 Evolva Sa Increased production of terpenes and terpenoids
WO2015083769A1 (ja) * 2013-12-04 2015-06-11 国立研究開発法人理化学研究所 光合成のみによるポリヒドロキシアルカン酸の生産
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
WO2018208116A1 (ko) * 2017-05-11 2018-11-15 경상대학교산학협력단 형질전환 생물체 선별용 마커 조성물, 형질전환 생물체 및 형질전환 방법
EP3623480A4 (en) 2017-05-11 2021-02-24 Industry-Academic Cooperation Foundation Gyeongsang National University COMPOSITION OF MARKER FOR SELECTING A LIVING MODIFIED ORGANISM, LIVING MODIFIED ORGANISM AND PROCESS OF TRANSFORMATION
CN110317765B (zh) * 2018-03-29 2020-11-20 中国科学院天津工业生物技术研究所 一种高产香叶醇葡萄糖苷的大肠杆菌表达菌株及其应用
CN113366009B (zh) * 2018-11-27 2025-02-11 科纳科学控股有限公司 用于生物合成大麻素的双向多酶支架
CN112553134B (zh) * 2020-12-30 2022-09-06 江南大学 一种在枯草芽孢杆菌中表达α-淀粉酶的方法

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US20110159557A1 (en) * 2009-12-23 2011-06-30 Danisco Us Inc. Compositions and methods of pgl for the increased production of isoprene

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US20050287655A1 (en) 2002-05-10 2005-12-29 Kyowa Hakko Kogyo Co., Ltd. Process for producing mevalonic acid
AU2003287028B2 (en) 2002-10-04 2008-09-04 E.I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high yield
RU2004124226A (ru) 2004-08-10 2006-01-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Использование фосфокетолазы для продукции полезных метаболитов
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018014960A (ja) * 2016-07-29 2018-02-01 横浜ゴム株式会社 発現ベクター、形質転換された藻類、形質転換された珪藻、及び、ポリヌクレオチド
JP2023524097A (ja) * 2020-04-30 2023-06-08 ストロ バイオファーマ, インコーポレイテッド 大腸菌を用いた全長抗体の作製方法
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SG11201403163QA (en) 2014-09-26
CA2859885A1 (en) 2013-06-27
EP2794863A1 (en) 2014-10-29
US9388431B2 (en) 2016-07-12
US20130164808A1 (en) 2013-06-27
US8975051B2 (en) 2015-03-10
CN104245927A (zh) 2014-12-24
US20150218590A1 (en) 2015-08-06
AU2012358149A1 (en) 2014-07-03
MX2014007623A (es) 2015-02-04
WO2013096925A1 (en) 2013-06-27
BR112014014947A2 (pt) 2020-10-27

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